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Neil Dalvie, Ph.D.

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Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Dalvie NC, Naranjo CA, Rodriguez-Aponte SA, Johnston RS, Christopher Love J. Steric accessibility of the N-terminus improves the titer and quality of recombinant proteins secreted from Komagataella phaffii. Microb Cell Fact. 2022 Sep 05; 21(1):180. PMID: 36064410; PMCID: PMC9444097.
    Citations:    Fields:    
  2. Wong TY, Russ BP, Lee KS, Miller OA, Kang J, Cooper M, Winters MT, Rodriguez-Aponte SA, Dalvie NC, Johnston RS, Rader NA, Wong ZY, Cyphert HA, Martinez I, Shaligram U, Batwal S, Lothe R, Chandrasekaran R, Nagar G, Rajurkar M, Rao H, Bevere JR, Barbier M, Love JC, Damron FH. RBD-VLP Vaccines Adjuvanted with Alum or SWE Protect K18-hACE2 Mice against SARS-CoV-2 VOC Challenge. mSphere. 2022 08 31; 7(4):e0024322. PMID: 35968964; PMCID: PMC9429941.
    Citations:    Fields:    
  3. Hartwell BL, Melo MB, Xiao P, Lemnios AA, Li N, Chang JYH, Yu J, Gebre MS, Chang A, Maiorino L, Carter C, Moyer TJ, Dalvie NC, Rodriguez-Aponte SA, Rodrigues KA, Silva M, Suh H, Adams J, Fontenot J, Love JC, Barouch DH, Villinger F, Ruprecht RM, Irvine DJ. Intranasal vaccination with lipid-conjugated immunogens promotes antigen transmucosal uptake to drive mucosal and systemic immunity. Sci Transl Med. 2022 07 20; 14(654):eabn1413. PMID: 35857825.
    Citations:    Fields:    Translation:AnimalsCellsPHPublic Health
  4. Bajoria S, Kaur K, Kumru OS, Van Slyke G, Doering J, Novak H, Rodriguez Aponte SA, Dalvie NC, Naranjo CA, Johnston RS, Silverman JM, Kleanthous H, Love JC, Mantis NJ, Joshi SB, Volkin DB. Antigen-adjuvant interactions, stability, and immunogenicity profiles of a SARS-CoV-2 receptor-binding domain (RBD) antigen formulated with aluminum salt and CpG adjuvants. Hum Vaccin Immunother. 2022 11 30; 18(5):2079346. PMID: 35666264; PMCID: PMC9621007.
    Citations:    Fields:    
  5. Dalvie NC, Tostanoski LH, Rodriguez-Aponte SA, Kaur K, Bajoria S, Kumru OS, Martinot AJ, Chandrashekar A, McMahan K, Mercado NB, Yu J, Chang A, Giffin VM, Nampanya F, Patel S, Bowman L, Naranjo CA, Yun D, Flinchbaugh Z, Pessaint L, Brown R, Velasco J, Teow E, Cook A, Andersen H, Lewis MG, Camp DL, Silverman JM, Nagar GS, Rao HD, Lothe RR, Chandrasekharan R, Rajurkar MP, Shaligram US, Kleanthous H, Joshi SB, Volkin DB, Biswas S, Love JC, Barouch DH. SARS-CoV-2 receptor binding domain displayed on HBsAg virus-like particles elicits protective immunity in macaques. Sci Adv. 2022 Mar 18; 8(11):eabl6015. PMID: 35294244; PMCID: PMC8926328.
    Citations: 4     Fields:    
  6. Dalvie NC, Lorgeree T, Biedermann AM, Love KR, Love JC. Simplified Gene Knockout by CRISPR-Cas9-Induced Homologous Recombination. ACS Synth Biol. 2022 01 21; 11(1):497-501. PMID: 34882409; PMCID: PMC8787811.
    Citations:    Fields:    Translation:Cells
  7. Rodrigues KA, Rodriguez-Aponte SA, Dalvie NC, Lee JH, Abraham W, Carnathan DG, Jimenez LE, Ngo JT, Chang JYH, Zhang Z, Yu J, Chang A, Nakao C, Goodwin B, Naranjo CA, Zhang L, Silva M, Barouch DH, Silvestri G, Crotty S, Love JC, Irvine DJ. Phosphate-mediated coanchoring of RBD immunogens and molecular adjuvants to alum potentiates humoral immunity against SARS-CoV-2. Sci Adv. 2021 Dec 10; 7(50):eabj6538. PMID: 34878851; PMCID: PMC8654298.
    Citations: 1     Fields:    
  8. Dalvie NC, Biedermann AM, Rodriguez-Aponte SA, Naranjo CA, Rao HD, Rajurkar MP, Lothe RR, Shaligram US, Johnston RS, Crowell LE, Castelino S, Tracey MK, Whittaker CA, Love JC. Scalable, methanol-free manufacturing of the SARS-CoV-2 receptor-binding domain in engineered Komagataella phaffii. Biotechnol Bioeng. 2022 02; 119(2):657-662. PMID: 34780057; PMCID: PMC8653030.
    Citations: 5     Fields:    
  9. Dalvie NC, Rodriguez-Aponte SA, Hartwell BL, Tostanoski LH, Biedermann AM, Crowell LE, Kaur K, Kumru OS, Carter L, Yu J, Chang A, McMahan K, Courant T, Lebas C, Lemnios AA, Rodrigues KA, Silva M, Johnston RS, Naranjo CA, Tracey MK, Brady JR, Whittaker CA, Yun D, Brunette N, Wang JY, Walkey C, Fiala B, Kar S, Porto M, Lok M, Andersen H, Lewis MG, Love KR, Camp DL, Silverman JM, Kleanthous H, Joshi SB, Volkin DB, Dubois PM, Collin N, King NP, Barouch DH, Irvine DJ, Love JC. Engineered SARS-CoV-2 receptor binding domain improves manufacturability in yeast and immunogenicity in mice. Proc Natl Acad Sci U S A. 2021 09 21; 118(38). PMID: 34493582.
    Citations: 23     Fields:    Translation:HumansAnimalsCells
  10. Dalvie NC, Tostanoski LH, Rodriguez-Aponte SA, Kaur K, Bajoria S, Kumru OS, Martinot AJ, Chandrashekar A, McMahan K, Mercado NB, Yu J, Chang A, Giffin VM, Nampanya F, Patel S, Bowman L, Naranjo CA, Yun D, Flinchbaugh Z, Pessaint L, Brown R, Velasco J, Teow E, Cook A, Andersen H, Lewis MG, Camp DL, Silverman JM, Kleanthous H, Joshi SB, Volkin DB, Biswas S, Love JC, Barouch DH. A modular protein subunit vaccine candidate produced in yeast confers protection against SARS-CoV-2 in non-human primates. bioRxiv. 2021 Jul 14. PMID: 34282417.
    Citations:    
  11. Dalvie NC, Brady JR, Crowell LE, Tracey MK, Biedermann AM, Kaur K, Hickey JM, Kristensen DL, Bonnyman AD, Rodriguez-Aponte SA, Whittaker CA, Bok M, Vega C, Mukhopadhyay TK, Joshi SB, Volkin DB, Parreño V, Love KR, Love JC. Molecular engineering improves antigen quality and enables integrated manufacturing of a trivalent subunit vaccine candidate for rotavirus. Microb Cell Fact. 2021 May 01; 20(1):94. PMID: 33933073; PMCID: PMC8088319.
    Citations: 5     Fields:    Translation:AnimalsCells
  12. Dalvie NC, Biedermann AM, Rodriguez-Aponte SA, Naranjo CA, Rao HD, Rajurkar MP, Lothe RR, Shaligram US, Johnston RS, Crowell LE, Castelino S, Tracey MK, Whittaker CA, Love JC. Scalable, methanol-free manufacturing of the SARS-CoV-2 receptor binding domain in engineered Komagataella phaffii. bioRxiv. 2021 Apr 15. PMID: 33880471; PMCID: PMC8057236.
    Citations:    
  13. Crowell LE, Goodwine C, Holt CS, Rocha L, Vega C, Rodriguez SA, Dalvie NC, Tracey MK, Puntel M, Wigdorovitz A, Parreño V, Love KR, Cramer SM, Love JC. Development of a platform process for the production and purification of single-domain antibodies. Biotechnol Bioeng. 2021 09; 118(9):3348-3358. PMID: 33624832; PMCID: PMC8451865.
    Citations: 4     Fields:    Translation:AnimalsCells
  14. Dalvie NC, Rodriguez-Aponte SA, Hartwell BL, Tostanoski LH, Biedermann AM, Crowell LE, Kaur K, Kumru O, Carter L, Yu J, Chang A, McMahan K, Courant T, Lebas C, Lemnios AA, Rodrigues KA, Silva M, Johnston RS, Naranjo CA, Tracey MK, Brady JR, Whittaker CA, Yun D, Kar S, Porto M, Lok M, Andersen H, Lewis MG, Love KR, Camp DL, Silverman JM, Kleanthous H, Joshi SB, Volkin DB, Dubois PM, Collin N, King NP, Barouch DH, Irvine DJ, Love JC. Engineered SARS-CoV-2 receptor binding domain improves immunogenicity in mice and elicits protective immunity in hamsters. bioRxiv. 2021 Mar 04. PMID: 33688647.
    Citations: 4     
  15. Lu AE, Maloney AJ, Dalvie NC, Brady JR, Love KR, Love JC, Braatz RD. Modeling of copy number variability in Pichia pastoris. Biotechnol Bioeng. 2021 05; 118(5):1832-1839. PMID: 33527350.
    Citations:    Fields:    Translation:Animals
  16. Sawant N, Kaur K, Holland DA, Hickey JM, Agarwal S, Brady JR, Dalvie NC, Tracey MK, Velez-Suberbie ML, Morris SA, Jacob SI, Bracewell DG, Mukhopadhyay TK, Love KR, Love JC, Joshi SB, Volkin DB. Rapid Developability Assessments to Formulate Recombinant Protein Antigens as Stable, Low-Cost, Multi-Dose Vaccine Candidates: Case-Study With Non-Replicating Rotavirus (NRRV) Vaccine Antigens. J Pharm Sci. 2021 03; 110(3):1042-1053. PMID: 33285182; PMCID: PMC7884052.
    Citations: 4     Fields:    Translation:AnimalsCells
  17. Kaur K, Xiong J, Sawant N, Agarwal S, Hickey JM, Holland DA, Mukhopadhyay TK, Brady JR, Dalvie NC, Tracey MK, Love KR, Love JC, Weis DD, Joshi SB, Volkin DB. Mechanism of Thimerosal-Induced Structural Destabilization of a Recombinant Rotavirus P[4] Protein Antigen Formulated as a Multi-Dose Vaccine. J Pharm Sci. 2021 03; 110(3):1054-1066. PMID: 33278412; PMCID: PMC7884053.
    Citations: 2     Fields:    Translation:Cells
  18. Brady JR, Tan MC, Whittaker CA, Colant NA, Dalvie NC, Love KR, Love JC. Identifying Improved Sites for Heterologous Gene Integration Using ATAC-seq. ACS Synth Biol. 2020 09 18; 9(9):2515-2524. PMID: 32786350; PMCID: PMC7506950.
    Citations: 3     Fields:    Translation:Animals
  19. Dalvie NC, Leal J, Whittaker CA, Yang Y, Brady JR, Love KR, Love JC. Host-Informed Expression of CRISPR Guide RNA for Genomic Engineering in Komagataella phaffii. ACS Synth Biol. 2020 01 17; 9(1):26-35. PMID: 31825599; PMCID: PMC7814401.
    Citations: 17     Fields:    Translation:AnimalsCells
  20. Brady JR, Whittaker CA, Tan MC, Kristensen DL, Ma D, Dalvie NC, Love KR, Love JC. Comparative genome-scale analysis of Pichia pastoris variants informs selection of an optimal base strain. Biotechnol Bioeng. 2020 02; 117(2):543-555. PMID: 31654411; PMCID: PMC7003935.
    Citations: 14     Fields:    Translation:AnimalsCells
  21. Crowell LE, Lu AE, Love KR, Stockdale A, Timmick SM, Wu D, Wang YA, Doherty W, Bonnyman A, Vecchiarello N, Goodwine C, Bradbury L, Brady JR, Clark JJ, Colant NA, Cvetkovic A, Dalvie NC, Liu D, Liu Y, Mascarenhas CA, Matthews CB, Mozdzierz NJ, Shah KA, Wu SL, Hancock WS, Braatz RD, Cramer SM, Love JC. On-demand manufacturing of clinical-quality biopharmaceuticals. Nat Biotechnol. 2018 Oct 01. PMID: 30272677; PMCID: PMC6443493.
    Citations: 20     Fields:    
  22. Love KR, Dalvie NC, Love JC. The yeast stands alone: the future of protein biologic production. Curr Opin Biotechnol. 2018 10; 53:50-58. PMID: 29277062.
    Citations: 23     Fields:    Translation:Animals
  23. Younger AK, Dalvie NC, Rottinghaus AG, Leonard JN. Engineering Modular Biosensors to Confer Metabolite-Responsive Regulation of Transcription. ACS Synth Biol. 2017 Feb 17; 6(2):311-325. PMID: 27744683.
    Citations: 10     Fields:    Translation:Cells
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.