Harvard Catalyst Profiles

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Takeshi Okada, Ph.D., M.D.

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Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Kanno K, Koseki M, Chang J, Saga A, Inui H, Okada T, Tanaka K, Asaji M, Zhu Y, Ide S, Saito S, Higo T, Okuzaki D, Ohama T, Nishida M, Kamada Y, Ono M, Saibara T, Yamashita S, Sakata Y. Pemafibrate suppresses NLRP3 inflammasome activation in the liver and heart in a novel mouse model of steatohepatitis-related cardiomyopathy. Sci Rep. 2022 02 22; 12(1):2996. PMID: 35194060.
    Citations: 1     Fields:    Translation:Animals
  2. Tanaka K, Koseki M, Kato H, Miyashita K, Okada T, Kanno K, Saga A, Chang J, Omatsu T, Inui H, Ohama T, Nishida M, Yamashita S, Sakata Y. Anti-GPIHBP1 Antibody-Positive Autoimmune Hyperchylomicronemia and Immune Thrombocytopenia. J Atheroscler Thromb. 2022 Feb 18. PMID: 35185060.
    Citations:    Fields:    
  3. Chang J, Koseki M, Saga A, Kanno K, Higo T, Okuzaki D, Okada T, Inui H, Tanaka K, Asaji M, Zhu Y, Kamada Y, Ono M, Saibara T, Ichi I, Ohama T, Nishida M, Yamashita S, Sakata Y. Dietary Oxysterol, 7-Ketocholesterol Accelerates Hepatic Lipid Accumulation and Macrophage Infiltration in Obese Mice. Front Endocrinol (Lausanne). 2020; 11:614692. PMID: 33776901.
    Citations: 4     Fields:    Translation:AnimalsCells
  4. Nishikawa R, Furuhashi M, Hori M, Ogura M, Harada-Shiba M, Okada T, Koseki M, Kujiraoka T, Hattori H, Ito R, Muranaka A, Kokubu N, Miura T. A Resuscitated Case of Acute Myocardial Infarction with both Familial Hypercholesterolemia Phenotype Caused by Possibly Oligogenic Variants of the PCSK9 and ABCG5 Genes and Type I CD36 Deficiency. J Atheroscler Thromb. 2022 Apr 01; 29(4):551-557. PMID: 33642439; PMCID: PMC9090482.
    Citations: 1     Fields:    Translation:Humans
  5. Yamashita S, Okazaki M, Okada T, Masuda D, Yokote K, Arai H, Araki E, Ishibashi S. Distinct Differences in Lipoprotein Particle Number Evaluation between GP-HPLC and NMR: Analysis in Dyslipidemic Patients Administered a Selective PPARa Modulator, Pemafibrate. J Atheroscler Thromb. 2021 Sep 01; 28(9):974-996. PMID: 33536398.
    Citations: 4     Fields:    Translation:HumansCTClinical Trials
  6. Okada T, Sumida M, Ohama T, Katayama Y, Saga A, Inui H, Kanno K, Masuda D, Koseki M, Nishida M, Sakata Y, Yamashita S. Development and Clinical Application of an Enzyme-Linked Immunosorbent Assay for Oxidized High-Density Lipoprotein. J Atheroscler Thromb. 2021 Jul 01; 28(7):703-715. PMID: 33028763; PMCID: PMC8265427.
    Citations: 3     Fields:    Translation:HumansCells
  7. Zhu Y, Ohama T, Kawase R, Chang J, Inui H, Kanno K, Okada T, Masuda D, Koseki M, Nishida M, Sakata Y, Yamashita S. Progranulin deficiency leads to enhanced age-related cardiac hypertrophy through complement C1q-induced ß-catenin activation. J Mol Cell Cardiol. 2020 01; 138:197-211. PMID: 31866375.
    Citations: 5     Fields:    Translation:AnimalsCells
  8. Liu J, Nishida M, Inui H, Chang J, Zhu Y, Kanno K, Matsuda H, Sairyo M, Okada T, Nakaoka H, Ohama T, Masuda D, Koseki M, Yamashita S, Sakata Y. Rivaroxaban Suppresses the Progression of Ischemic Cardiomyopathy in a Murine Model of Diet-Induced Myocardial Infarction. J Atheroscler Thromb. 2019 Oct 01; 26(10):915-930. PMID: 30867376.
    Citations: 10     Fields:    Translation:Animals
  9. Okada T, Ohama T, Takafuji K, Kanno K, Matsuda H, Sairyo M, Zhu Y, Saga A, Kobayashi T, Masuda D, Koseki M, Nishida M, Sakata Y, Yamashita S. Shotgun proteomic analysis reveals proteome alterations in HDL of patients with cholesteryl ester transfer protein deficiency. J Clin Lipidol. 2019 Mar - Apr; 13(2):317-325. PMID: 30745272.
    Citations: 7     Fields:    Translation:Humans
  10. Nakatani K, Masuda D, Kobayashi T, Sairyo M, Zhu Y, Okada T, Naito AT, Ohama T, Koseki M, Oka T, Akazawa H, Nishida M, Komuro I, Sakata Y, Yamashita S. Pressure Overload Impairs Cardiac Function in Long-Chain Fatty Acid Transporter CD36-Knockout Mice. Int Heart J. 2019 Jan 25; 60(1):159-167. PMID: 30518717.
    Citations: 5     Fields:    Translation:AnimalsCells
  11. Okada T, Ohama T, Okazaki M, Kanno K, Matsuda H, Sairyo M, Zhu Y, Saga A, Kobayashi T, Masuda D, Koseki M, Nishida M, Sakata Y, Yamashita S. Particle number analysis of lipoprotein subclasses by gel permeation HPLC in patients with cholesteryl ester transfer protein deficiency. PLoS One. 2018; 13(1):e0190875. PMID: 29304079.
    Citations: 5     Fields:    Translation:Humans
  12. Sairyo M, Kobayashi T, Masuda D, Kanno K, Zhu Y, Okada T, Koseki M, Ohama T, Nishida M, Sakata Y, Yamashita S. A Novel Selective PPARa Modulator (SPPARMa), K-877 (Pemafibrate), Attenuates Postprandial Hypertriglyceridemia in Mice. J Atheroscler Thromb. 2018 Feb 01; 25(2):142-152. PMID: 28781340.
    Citations: 24     Fields:    Translation:Animals
  13. Nakatani K, Watabe T, Masuda D, Imaizumi M, Shimosegawa E, Kobayashi T, Sairyo M, Zhu Y, Okada T, Kawase R, Nakaoka H, Naito A, Ohama T, Koseki M, Oka T, Akazawa H, Nishida M, Komuro I, Sakata Y, Hatazawa J, Yamashita S. Myocardial energy provision is preserved by increased utilization of glucose and ketone bodies in CD36 knockout mice. Metabolism. 2015 Sep; 64(9):1165-74. PMID: 26130608.
    Citations: 11     Fields:    Translation:Animals
  14. Nakaoka H, Nakagawa-Toyama Y, Nishida M, Okada T, Kawase R, Yamashita T, Yuasa-Kawase M, Nakatani K, Masuda D, Ohama T, Sonobe T, Shirai M, Komuro I, Yamashita S. Establishment of a novel murine model of ischemic cardiomyopathy with multiple diffuse coronary lesions. PLoS One. 2013; 8(8):e70755. PMID: 23950999.
    Citations: 6     Fields:    Translation:Animals
  15. Kawase R, Ohama T, Matsuyama A, Matsuwaki T, Okada T, Yamashita T, Yuasa-Kawase M, Nakaoka H, Nakatani K, Inagaki M, Tsubakio-Yamamoto K, Masuda D, Nakagawa-Toyama Y, Nishida M, Ohmoto Y, Nishihara M, Komuro I, Yamashita S. Deletion of progranulin exacerbates atherosclerosis in ApoE knockout mice. Cardiovasc Res. 2013 Oct 01; 100(1):125-33. PMID: 23847387.
    Citations: 41     Fields:    Translation:HumansAnimalsCells
  16. Ueda H, Yamada T, Masuda M, Morita T, Furukawa Y, Tanaka K, Iwasaki Y, Okada T, Kawasaki M, Kuramoto Y, Naito T, Fujimoto T, Komuro I, Fukunami M. Kidney enhancement on X-rays following emergency percutaneous coronary procedure predicts poor short- and long-term clinical outcomes. Circ J. 2013; 77(4):982-7. PMID: 23258216.
    Citations:    Fields:    Translation:HumansCTClinical Trials
  17. Furukawa Y, Yamada T, Okuyama Y, Morita T, Tanaka K, Iwasaki Y, Ueda H, Okada T, Kawasaki M, Kuramoto Y, Fukunami M. Increased intraatrial conduction abnormality assessed by P-wave signal-averaged electrocardiogram in patients with Brugada syndrome. Pacing Clin Electrophysiol. 2011 Sep; 34(9):1138-46. PMID: 21605130.
    Citations: 5     Fields:    Translation:Humans
  18. Ueda H, Yamada T, Masuda M, Okuyama Y, Morita T, Furukawa Y, Koji T, Iwasaki Y, Okada T, Kawasaki M, Kuramoto Y, Naito T, Fujimoto T, Komuro I, Fukunami M. Prevention of contrast-induced nephropathy by bolus injection of sodium bicarbonate in patients with chronic kidney disease undergoing emergent coronary procedures. Am J Cardiol. 2011 Apr 15; 107(8):1163-7. PMID: 21349483.
    Citations: 20     Fields:    Translation:Humans
  19. Kuramoto Y, Yamada T, Tamaki S, Okuyama Y, Morita T, Furukawa Y, Tanaka K, Iwasaki Y, Yasui T, Ueda H, Okada T, Kawasaki M, Levy WC, Komuro I, Fukunami M. Usefulness of cardiac iodine-123 meta-iodobenzylguanidine imaging to improve prognostic power of Seattle heart failure model in patients with chronic heart failure. Am J Cardiol. 2011 Apr 15; 107(8):1185-90. PMID: 21349482.
    Citations: 7     Fields:    Translation:Humans
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.