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George Charles Linderman, M.D.


Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Linderman GC, Zhao J, Roulis M, Bielecki P, Flavell RA, Nadler B, Kluger Y. Zero-preserving imputation of single-cell RNA-seq data. Nat Commun. 2022 01 11; 13(1):192. PMID: 35017482; PMCID: PMC8752663.
    Citations: 1     Fields:    Translation:HumansAnimalsCells
  2. Linderman GC, Schuster KM. Authors' response to the letter to the editor by McDonough and Dimitrakoff. J Trauma Acute Care Surg. 2021 11 01; 91(5):e128. PMID: 34254957.
    Citations:    Fields:    
  3. Linderman GC, Lin W, Becher RD, Maung AA, Bhattacharya B, Davis KA, Schuster KM. Increased mortality with resuscitative endovascular balloon occlusion of the aorta only mitigated by strong unmeasured confounding: An expanded analysis using the National Trauma Data Bank. J Trauma Acute Care Surg. 2021 11 01; 91(5):790-797. PMID: 33951027; PMCID: PMC8547242.
    Citations:    Fields:    Translation:Humans
  4. Linderman GC, Lin W, Sanghvi MR, Becher RD, Maung AA, Bhattacharya B, Davis KA, Schuster KM. Improved outcomes using laparoscopy for emergency colectomy after mitigating bias by negative control exposure analysis. Surgery. 2022 02; 171(2):305-311. PMID: 34332782.
    Citations:    Fields:    Translation:HumansPHPublic Health
  5. Kobak D, Linderman GC. Initialization is critical for preserving global data structure in both t-SNE and UMAP. Nat Biotechnol. 2021 02; 39(2):156-157. PMID: 33526945.
    Citations: 17     Fields:    
  6. Linderman GC. Dimensionality Reduction of Single-Cell RNA-Seq Data. Methods Mol Biol. 2021; 2284:331-342. PMID: 33835451.
    Citations: 1     Fields:    Translation:HumansAnimals
  7. Mori M, Brooks C, Spatz E, Mortazavi BJ, Dhruva SS, Linderman GC, Grab LA, Zhang Y, Geirsson A, Chaudhry SI, Krumholz HM. Protocol for project recovery after cardiac surgery: a single-center cohort study leveraging digital platform to characterise longitudinal patient-reported postoperative recovery patterns. BMJ Open. 2020 09 01; 10(9):e036959. PMID: 32873671.
    Citations: 1     Fields:    Translation:Humans
  8. Linderman GC, Mishne G, Jaffe A, Kluger Y, Steinerberger S. Randomized near-neighbor graphs, giant components and applications in data science. J Appl Probab. 2020 Jun; 57(2):458-476. PMID: 32913373.
    Citations: 1     
  9. Kobak D, Linderman G, Steinerberger S, Kluger Y, Berens P. Heavy-tailed kernels reveal a finer cluster structure in t-SNE visualisations. Mach Learn Knowl Discov Databases. 2020; 11906:124-139. PMID: 33103160.
  10. Linderman GC, Steinerberger S. NUMERICAL INTEGRATION ON GRAPHS: WHERE TO SAMPLE AND HOW TO WEIGH. Math Comput. 2020; 89(324):1933-1952. PMID: 33927452.
  11. Raredon MSB, Adams TS, Suhail Y, Schupp JC, Poli S, Neumark N, Leiby KL, Greaney AM, Yuan Y, Horien C, Linderman G, Engler AJ, Boffa DJ, Kluger Y, Rosas IO, Levchenko A, Kaminski N, Niklason LE. Single-cell connectomic analysis of adult mammalian lungs. Sci Adv. 2019 12; 5(12):eaaw3851. PMID: 31840053.
    Citations: 55     Fields:    Translation:HumansAnimalsCells
  12. Li DT, Linderman GC, Cui JJ, DeVries S, Nicholson AD, Li E, Petit L, Kahan JB, Talty R, Kluger Y, Cooperman DR, Smith BG. The Proximal Humeral Ossification System Improves Assessment of Maturity in Patients with Scoliosis. J Bone Joint Surg Am. 2019 Oct 16; 101(20):1868-1874. PMID: 31626012; PMCID: PMC7515481.
    Citations: 5     Fields:    Translation:Humans
  13. Linderman GC, Steinerberger S. Clustering with t-SNE, provably. SIAM J Math Data Sci. 2019; 1(2):313-332. PMID: 33073204.
    Citations: 8     
  14. Linderman GC, Rachh M, Hoskins JG, Steinerberger S, Kluger Y. Fast interpolation-based t-SNE for improved visualization of single-cell RNA-seq data. Nat Methods. 2019 03; 16(3):243-245. PMID: 30742040.
    Citations: 90     Fields:    Translation:AnimalsCells
  15. Gupta K, Levinsohn J, Linderman G, Chen D, Sun TY, Dong D, Taketo MM, Bosenberg M, Kluger Y, Choate K, Myung P. Single-Cell Analysis Reveals a Hair Follicle Dermal Niche Molecular Differentiation Trajectory that Begins Prior to Morphogenesis. Dev Cell. 2019 01 07; 48(1):17-31.e6. PMID: 30595533; PMCID: PMC6361530.
    Citations: 23     Fields:    Translation:Cells
  16. Linderman GC, Lu J, Lu Y, Sun X, Xu W, Nasir K, Schulz W, Jiang L, Krumholz HM. Association of Body Mass Index With Blood Pressure Among 1.7 Million Chinese Adults. JAMA Netw Open. 2018 08 03; 1(4):e181271. PMID: 30646115; PMCID: PMC6324286.
    Citations: 28     Fields:    Translation:Humans
  17. Lu J, Lu Y, Wang X, Li X, Linderman GC, Wu C, Cheng X, Mu L, Zhang H, Liu J, Su M, Zhao H, Spatz ES, Spertus JA, Masoudi FA, Krumholz HM, Jiang L. Prevalence, awareness, treatment, and control of hypertension in China: data from 1·7 million adults in a population-based screening study (China PEACE Million Persons Project). Lancet. 2017 Dec 09; 390(10112):2549-2558. PMID: 29102084.
    Citations: 299     Fields:    Translation:HumansPHPublic Health
  18. Li H, Linderman GC, Szlam A, Stanton KP, Kluger Y, Tygert M. Algorithm 971: An Implementation of a Randomized Algorithm for Principal Component Analysis. ACM Trans Math Softw. 2017 Jan; 43(3). PMID: 28983138; PMCID: PMC5625842.
    Citations: 4     
  19. Jenkins MW, Linderman GC, Bezerra HG, Fujino Y, Costa MA, Wilson DL, Rollins AM. 3-D Stent Detection in Intravascular OCT Using a Bayesian Network and Graph Search. IEEE Trans Med Imaging. 2015 Jul; 34(7):1549-1561. PMID: 25751863.
    Citations: 11     Fields:    
  20. Linderman GC, Chance MR, Bebek G. MAGNET: MicroArray Gene expression and Network Evaluation Toolkit. Nucleic Acids Res. 2012 Jul; 40(Web Server issue):W152-6. PMID: 22669910.
    Citations: 7     Fields:    Translation:Cells
  21. Linderman GC, Patel VN, Chance MR, Bebek G. BiC: a web server for calculating bimodality of coexpression between gene and protein networks. Bioinformatics. 2011 Apr 15; 27(8):1174-5. PMID: 21345871.
    Citations:    Fields:    
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.