Harvard Catalyst Profiles

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Robert Lawrence Dilley, M.D., Ph.D.

Title
Institution
Department
Address

Biography
Johns Hopkins University, Baltimore, USABS12/2011Molecular/cell biology
University of Pennsylvania, Philadelphia, USAPhD12/2018Molecular/cell biology
University of Pennsylvania, Philadelphia, USAMD05/2021

Research
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. F30GM120905 (DILLEY, ROBERT LAWRENCE) Aug 1, 2016 - Jul 31, 2018
    NIH
    Mechanisms of DNA synthesis during alternative lengthening of telomeres
    Role: Principal Investigator

Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Zhang H, Zhao R, Tones J, Liu M, Dilley RL, Chenoweth DM, Greenberg RA, Lampson MA. Nuclear body phase separation drives telomere clustering in ALT cancer cells. Mol Biol Cell. 2020 08 15; 31(18):2048-2056. PMID: 32579423.
    Citations: 47     Fields:    Translation:HumansCells
  2. Verma P, Dilley RL, Zhang T, Gyparaki MT, Li Y, Greenberg RA. RAD52 and SLX4 act nonepistatically to ensure telomere stability during alternative telomere lengthening. Genes Dev. 2019 02 01; 33(3-4):221-235. PMID: 30692206; PMCID: PMC6362809.
    Citations: 51     Fields:    Translation:HumansCells
  3. Poh W, Dilley RL, Moliterno AR, Maciejewski JP, Pratz KW, McDevitt MA, Herman JG. BRCA1 Promoter Methylation Is Linked to Defective Homologous Recombination Repair and Elevated miR-155 to Disrupt Myeloid Differentiation in Myeloid Malignancies. Clin Cancer Res. 2019 04 15; 25(8):2513-2522. PMID: 30692098.
    Citations: 6     Fields:    Translation:HumansCells
  4. Verma P, Dilley RL, Gyparaki MT, Greenberg RA. Direct Quantitative Monitoring of Homology-Directed DNA Repair of Damaged Telomeres. Methods Enzymol. 2018; 600:107-134. PMID: 29458755.
    Citations: 5     Fields:    Translation:HumansCells
  5. Dilley RL, Verma P, Cho NW, Winters HD, Wondisford AR, Greenberg RA. Break-induced telomere synthesis underlies alternative telomere maintenance. Nature. 2016 11 03; 539(7627):54-58. PMID: 27760120; PMCID: PMC5384111.
    Citations: 192     Fields:    Translation:HumansCells
  6. Pratz KW, Koh BD, Patel AG, Flatten KS, Poh W, Herman JG, Dilley R, Harrell MI, Smith BD, Karp JE, Swisher EM, McDevitt MA, Kaufmann SH. Poly (ADP-Ribose) Polymerase Inhibitor Hypersensitivity in Aggressive Myeloproliferative Neoplasms. Clin Cancer Res. 2016 08 01; 22(15):3894-902. PMID: 26979391; PMCID: PMC5041297.
    Citations: 15     Fields:    Translation:HumansCells
  7. Dilley RL, Greenberg RA. ALTernative Telomere Maintenance and Cancer. Trends Cancer. 2015 Oct 01; 1(2):145-156. PMID: 26645051.
    Citations: 112     Fields:    
  8. Cho NW, Dilley RL, Lampson MA, Greenberg RA. Interchromosomal homology searches drive directional ALT telomere movement and synapsis. Cell. 2014 Sep 25; 159(1):108-121. PMID: 25259924.
    Citations: 178     Fields:    Translation:HumansCells
  9. Dilley RL, Poh W, Gladstone DE, Herman JG, Showel MM, Karp JE, McDevitt MA, Pratz KW. Poly(ADP-ribose) polymerase inhibitor CEP-8983 synergizes with bendamustine in chronic lymphocytic leukemia cells in vitro. Leuk Res. 2014 Mar; 38(3):411-7. PMID: 24439051.
    Citations: 2     Fields:    Translation:HumansCells
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.