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Jakob Wollborn, M.D.

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Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Goebel U, Scheid S, Spassov S, Schallner N, Wollborn J, Buerkle H, Ulbrich F. Argon reduces microglial activation and inflammatory cytokine expression in retinal ischemia/reperfusion injury. Neural Regen Res. 2021 Jan; 16(1):192-198. PMID: 32788476.
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  2. Wollborn J, Jung C, Göbel U, Bruno RR. [Evaluation of the microcirculation in critically ill patients : Relevance, practical possibilities and scientific evidence]. Anaesthesist. 2020 Oct; 69(10):753-757. PMID: 32803320.
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  3. Bruno RR, Schemmelmann M, Wollborn J, Kelm M, Jung C. Evaluation of a shorter algorithm in an automated analysis of sublingual microcirculation. Clin Hemorheol Microcirc. 2020 Sep 07. PMID: 32925005.
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  4. Watchorn JC, Fargaly H, Gilani M, Assadi J, Deitchman AR, Naumann DN, Wollborn J, Goebel U, McCurdy MT, Hutchings SD. The Reproducibility of the Point of Care Microcirculation (POEM) Score When Used to Assess Critically Ill Patients: A Multicenter Prospective Observational Study. Shock. 2020 07; 54(1):15-20. PMID: 31764623.
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  5. Wollborn J, Steiger C, Doostkam S, Schallner N, Schroeter N, Kari FA, Meinel L, Buerkle H, Schick MA, Goebel U. Carbon Monoxide Exerts Functional Neuroprotection After Cardiac Arrest Using Extracorporeal Resuscitation in Pigs. Crit Care Med. 2020 Apr; 48(4):e299-e307. PMID: 32205620.
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  6. Schmidt J, Wenzel C, Spassov S, Borgmann S, Lin Z, Wollborn J, Weber J, Haberstroh J, Meckel S, Eiden S, Wirth S, Schumann S. Flow-Controlled Ventilation Attenuates Lung Injury in a Porcine Model of Acute Respiratory Distress Syndrome: A Preclinical Randomized Controlled Study. Crit Care Med. 2020 03; 48(3):e241-e248. PMID: 31856000.
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  7. Goebel U, Wollborn J. Carbon monoxide in intensive care medicine-time to start the therapeutic application?! Intensive Care Med Exp. 2020 Jan 09; 8(1):2. PMID: 31919605.
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  8. Wollborn J, Steiger C, Ruetten E, Benk C, Kari FA, Wunder C, Meinel L, Buerkle H, Schick MA, Goebel U. Carbon monoxide improves haemodynamics during extracorporeal resuscitation in pigs. Cardiovasc Res. 2020 01 01; 116(1):158-170. PMID: 30873524.
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  9. Kaiser S, Frase S, Selzner L, Lieberum JL, Wollborn J, Niesen WD, Foit NA, Heiland DH, Schallner N. Neuroprotection after Hemorrhagic Stroke Depends on Cerebral Heme Oxygenase-1. Antioxidants (Basel). 2019 Oct 19; 8(10). PMID: 31635102.
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  10. Wollborn J, Schlueter B, Steiger C, Hermann C, Wunder C, Schmidt J, Diel P, Meinel L, Buerkle H, Goebel U, Schick MA. Extracorporeal resuscitation with carbon monoxide improves renal function by targeting inflammatory pathways in cardiac arrest in pigs. Am J Physiol Renal Physiol. 2019 12 01; 317(6):F1572-F1581. PMID: 31482730.
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  11. Hopper CP, Wollborn J. Delivery of carbon monoxide via halogenated ether anesthetics. Nitric Oxide. 2019 08 01; 89:93-95. PMID: 31125687.
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  12. Wollborn J, Siemering S, Steiger C, Buerkle H, Goebel U, Schick MA. Phosphodiesterase-4 inhibition reduces ECLS-induced vascular permeability and improves microcirculation in a rodent model of extracorporeal resuscitation. . 2019 03 01; 316(3):H751-H761. PMID: 30681364.
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  13. Maier S, Goebel U, Krause S, Benk C, Schick MA, Buerkle H, Beyersdorf F, Kari FA, Wollborn J. Somatosensory and transcranial motor evoked potential monitoring in a porcine model for experimental procedures. PLoS One. 2018; 13(10):e0205410. PMID: 30296297.
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  14. Wollborn J, Hermann C, Goebel U, Merget B, Wunder C, Maier S, Schäfer T, Heuler D, Müller-Buschbaum K, Buerkle H, Meinel L, Schick MA, Steiger C. Overcoming safety challenges in CO therapy - Extracorporeal CO delivery under precise feedback control of systemic carboxyhemoglobin levels. J Control Release. 2018 06 10; 279:336-344. PMID: 29655987.
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  15. Wollborn J, Ruetten E, Schlueter B, Haberstroh J, Goebel U, Schick MA. Standardized model of porcine resuscitation using a custom-made resuscitation board results in optimal hemodynamic management. Am J Emerg Med. 2018 10; 36(10):1738-1744. PMID: 29395757.
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  16. Wollborn J, Schlegel N, Schick MA. [Phosphodiesterase 4 inhibition for treatment of endothelial barrier and microcirculation disorders in sepsis]. Anaesthesist. 2017 May; 66(5):347-352. PMID: 28429038.
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  17. Rosenbaum C, Schick MA, Wollborn J, Heider A, Scholz CJ, Cecil A, Niesler B, Hirrlinger J, Walles H, Metzger M. Activation of Myenteric Glia during Acute Inflammation In Vitro and In Vivo. PLoS One. 2016; 11(3):e0151335. PMID: 26964064.
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  18. Steiger C, Wollborn J, Gutmann M, Zehe M, Wunder C, Meinel L. Controlled therapeutic gas delivery systems for quality-improved transplants. Eur J Pharm Biopharm. 2015 Nov; 97(Pt A):96-106. PMID: 26527426.
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  19. Schick MA, Baar W, Bruno RR, Wollborn J, Held C, Schneider R, Flemming S, Schlegel N, Roewer N, Neuhaus W, Wunder C. Balanced Hydroxyethylstarch (HES 130/0.4) Impairs Kidney Function In-Vivo without Inflammation. PLoS One. 2015; 10(9):e0137247. PMID: 26340751.
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  20. Wollborn J, Wunder C, Stix J, Neuhaus W, Bruno RR, Baar W, Flemming S, Roewer N, Schlegel N, Schick MA. Phosphodiesterase-4 inhibition with rolipram attenuates hepatocellular injury in hyperinflammation in vivo and in vitro without influencing inflammation and HO-1 expression. J Pharmacol Pharmacother. 2015 Jan-Mar; 6(1):13-23. PMID: 25709347.
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  21. Schick MA, Baar W, Flemming S, Schlegel N, Wollborn J, Held C, Schneider R, Brock RW, Roewer N, Wunder C. Sepsis-induced acute kidney injury by standardized colon ascendens stent peritonitis in rats - a simple, reproducible animal model. Intensive Care Med Exp. 2014 Dec; 2(1):34. PMID: 26266931.
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  22. Flemming S, Schlegel N, Wunder C, Meir M, Baar W, Wollborn J, Roewer N, Germer CT, Schick MA. Phosphodiesterase 4 inhibition dose dependently stabilizes microvascular barrier functions and microcirculation in a rodent model of polymicrobial sepsis. Shock. 2014 Jun; 41(6):537-45. PMID: 24569506.
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  23. Schick MA, Wunder C, Wollborn J, Roewer N, Waschke J, Germer CT, Schlegel N. Phosphodiesterase-4 inhibition as a therapeutic approach to treat capillary leakage in systemic inflammation. J Physiol. 2012 Jun 01; 590(11):2693-708. PMID: 22495586.
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.