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Josephine Ann Carew, Ph.D.

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Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Chaudhury A, Cristofaro V, Carew JA, Goyal RK, Sullivan MP. Myosin Va plays a role in nitrergic smooth muscle relaxation in gastric fundus and corpora cavernosa of penis. PLoS One. 2014; 9(2):e86778. PMID: 24516539.
    Citations: 7     Fields:    Translation:Animals
  2. Cronin KR, Mangan TP, Carew JA. Upregulation of the coagulation factor VII gene during glucose deprivation is mediated by activating transcription factor 4. PLoS One. 2012; 7(7):e40994. PMID: 22848420.
    Citations: 1     Fields:    Translation:HumansCells
  3. Lopaciuk S, Windyga J, Watala CW, Bykowska K, Pietrucha T, Kwiecinski H, Czlonkowska A, Kuczynska-Zardzewialy A, Jackson AA, Carew JA, Bauer KA. Polymorphisms in the factor VII gene and ischemic stroke in young adults. Blood Coagul Fibrinolysis. 2010 Jul; 21(5):442-7. PMID: 20453637.
    Citations: 1     Fields:    Translation:Humans
  4. Jackson AA, Cronin KR, Zachariah R, Carew JA. CCAAT/enhancer-binding protein-beta participates in insulin-responsive expression of the factor VII gene. J Biol Chem. 2007 Oct 26; 282(43):31156-65. PMID: 17675296.
    Citations: 4     Fields:    Translation:HumansAnimalsCells
  5. Carew JA, Basso F, Miller GJ, Hawe E, Jackson AA, Humphries SE, Bauer KA. A functional haplotype in the 5' flanking region of the factor VII gene is associated with an increased risk of coronary heart disease. J Thromb Haemost. 2003 Oct; 1(10):2179-85. PMID: 14521602.
    Citations: 7     Fields:    Translation:HumansCells
  6. Carew JA, Jackson AA, Bauer KA. ARP1 interacts with the 5' flanking region of the coagulation factor VII gene. J Thromb Haemost. 2003 Jun; 1(6):1220-7. PMID: 12871323.
    Citations:    Fields:    Translation:HumansCells
  7. Peyvandi F, De Cristofaro R, Akhavan S, Carew JA, Landolfi R, Bauer KA, Mannucci PM. Two naturally occurring mutations on FVII gene (S363I-W364C) altering intrinsic catalytic activity. Thromb Haemost. 2002 Nov; 88(5):750-5. PMID: 12428089.
    Citations:    Fields:    Translation:HumansCells
  8. Peyvandi F, Carew JA, Perry DJ, Hunault M, Khanduri U, Perkins SJ, Mannucci PM, Bauer KA. Abnormal secretion and function of recombinant human factor VII as the result of modification to a calcium binding site caused by a 15-base pair insertion in the F7 gene. Blood. 2001 Feb 15; 97(4):960-5. PMID: 11159523.
    Citations:    Fields:    Translation:HumansCells
  9. Carew JA, Pollak ES, Lopaciuk S, Bauer KA. A new mutation in the HNF4 binding region of the factor VII promoter in a patient with severe factor VII deficiency. Blood. 2000 Dec 15; 96(13):4370-2. PMID: 11110717.
    Citations: 2     Fields:    Translation:HumansCells
  10. Hunault M, Arbini AA, Carew JA, Bauer KA. Mechanism underlying factor VII deficiency in Jewish populations with the Ala244Val mutation. Br J Haematol. 1999 Jun; 105(4):1101-8. PMID: 10554827.
    Citations:    Fields:    Translation:Humans
  11. Hunault M, Arbini AA, Carew JA, Peyvandi F, Bauer KA. Characterization of two naturally occurring mutations in the second epidermal growth factor-like domain of factor VII. Blood. 1999 Feb 15; 93(4):1237-44. PMID: 9949166.
    Citations: 3     Fields:    Translation:HumansAnimalsCells
  12. Carew JA, Pollak ES, High KA, Bauer KA. Severe factor VII deficiency due to a mutation disrupting an Sp1 binding site in the factor VII promoter. Blood. 1998 Sep 01; 92(5):1639-45. PMID: 9716591.
    Citations: 5     Fields:    Translation:HumansCells
  13. Hunault M, Arbini AA, Lopaciuk S, Carew JA, Bauer KA. The Arg353Gln polymorphism reduces the level of coagulation factor VII. In vivo and in vitro studies. Arterioscler Thromb Vasc Biol. 1997 Nov; 17(11):2825-9. PMID: 9409261.
    Citations: 9     Fields:    Translation:HumansAnimalsCells
  14. Luo C, Burgeon E, Carew JA, McCaffrey PG, Badalian TM, Lane WS, Hogan PG, Rao A. Recombinant NFAT1 (NFATp) is regulated by calcineurin in T cells and mediates transcription of several cytokine genes. Mol Cell Biol. 1996 Jul; 16(7):3955-66. PMID: 8668213.
    Citations: 55     Fields:    Translation:HumansAnimalsCells
  15. Loh C, Carew JA, Kim J, Hogan PG, Rao A. T-cell receptor stimulation elicits an early phase of activation and a later phase of deactivation of the transcription factor NFAT1. Mol Cell Biol. 1996 Jul; 16(7):3945-54. PMID: 8668212.
    Citations: 34     Fields:    Translation:AnimalsCells
  16. Loh C, Shaw KT, Carew J, Viola JP, Luo C, Perrino BA, Rao A. Calcineurin binds the transcription factor NFAT1 and reversibly regulates its activity. J Biol Chem. 1996 May 03; 271(18):10884-91. PMID: 8631904.
    Citations: 71     Fields:    Translation:AnimalsCells
  17. Carew JA, Quinn SM, Stoddart JH, Lynch DC. O-linked carbohydrate of recombinant von Willebrand factor influences ristocetin-induced binding to platelet glycoprotein 1b. J Clin Invest. 1992 Dec; 90(6):2258-67. PMID: 1469086.
    Citations: 10     Fields:    Translation:HumansCells
  18. Carew JA, Browning PJ, Lynch DC. Sulfation of von Willebrand factor. Blood. 1990 Dec 15; 76(12):2530-9. PMID: 2265247.
    Citations: 5     Fields:    Translation:Humans
  19. St Clair WH, Billings PC, Carew JA, Keller-McGandy C, Newberne P, Kennedy AR. Suppression of dimethylhydrazine-induced carcinogenesis in mice by dietary addition of the Bowman-Birk protease inhibitor. Cancer Res. 1990 Feb 01; 50(3):580-6. PMID: 2297699.
    Citations: 6     Fields:    Translation:Animals
  20. Carew JA, Kennedy AR. Identification of a proteolytic activity which responds to anticarcinogenic protease inhibitors in C3H-10T1/2 cells. Cancer Lett. 1990 Feb; 49(2):153-63. PMID: 2306709.
    Citations: 1     Fields:    Translation:AnimalsCells
  21. Carew JA, Collins MF, Kennedy AR. Inhibition of radiation-induced transformation in vitro by bacterial endotoxins. Carcinogenesis. 1988 May; 9(5):725-9. PMID: 3365832.
    Citations:    Fields:    Translation:AnimalsCells
  22. Billings PC, Carew JA, Keller-McGandy CE, Goldberg AL, Kennedy AR. A serine protease activity in C3H/10T1/2 cells that is inhibited by anticarcinogenic protease inhibitors. Proc Natl Acad Sci U S A. 1987 Jul; 84(14):4801-5. PMID: 3299374.
    Citations: 4     Fields:    Translation:AnimalsCells
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.