Harvard Catalyst Profiles

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Kow Akaa Essuman, Ph.D., M.D.


Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Essuman K, Milbrandt J, Dangl JL, Nishimura MT. Shared TIR enzymatic functions regulate cell death and immunity across the tree of life. Science. 2022 07 29; 377(6605):eabo0001. PMID: 35857622.
    Citations:    Fields:    
  2. Brace EJ, Essuman K, Mao X, Palucki J, Sasaki Y, Milbrandt J, DiAntonio A. Distinct developmental and degenerative functions of SARM1 require NAD+ hydrolase activity. PLoS Genet. 2022 06; 18(6):e1010246. PMID: 35737728; PMCID: PMC9223315.
    Citations: 1     Fields:    Translation:AnimalsCells
  3. Awad A, Essuman K, Regenhardt RW, Leslie-Mazwi TM, Patel AB, Stapleton CJ. Extensive Cerebral Arteriovenous Malformation-Associated Intraventricular Hemorrhage. Neurohospitalist. 2022 Apr; 12(2):418-419. PMID: 35419120; PMCID: PMC8995612.
  4. Wan L, Essuman K, Anderson RG, Sasaki Y, Monteiro F, Chung EH, Osborne Nishimura E, DiAntonio A, Milbrandt J, Dangl JL, Nishimura MT. TIR domains of plant immune receptors are NAD+-cleaving enzymes that promote cell death. Science. 2019 08 23; 365(6455):799-803. PMID: 31439793; PMCID: PMC7045805.
    Citations: 91     Fields:    Translation:AnimalsCells
  5. Essuman K, Summers DW, Sasaki Y, Mao X, Yim AKY, DiAntonio A, Milbrandt J. TIR Domain Proteins Are an Ancient Family of NAD+-Consuming Enzymes. Curr Biol. 2018 02 05; 28(3):421-430.e4. PMID: 29395922.
    Citations: 65     Fields:    Translation:AnimalsCells
  6. Essuman K, Summers DW, Sasaki Y, Mao X, DiAntonio A, Milbrandt J. The SARM1 Toll/Interleukin-1 Receptor Domain Possesses Intrinsic NAD+ Cleavage Activity that Promotes Pathological Axonal Degeneration. Neuron. 2017 Mar 22; 93(6):1334-1343.e5. PMID: 28334607.
    Citations: 179     Fields:    Translation:HumansAnimalsCells
  7. Schug J, McKenna LB, Walton G, Hand N, Mukherjee S, Essuman K, Shi Z, Gao Y, Markley K, Nakagawa M, Kameswaran V, Vourekas A, Friedman JR, Kaestner KH, Greenbaum LE. Dynamic recruitment of microRNAs to their mRNA targets in the regenerating liver. BMC Genomics. 2013 Apr 18; 14:264. PMID: 23597149.
    Citations: 41     Fields:    Translation:Animals
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.