Harvard Catalyst Profiles

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Laxman Ghimire, Ph.D.

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Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Balasubramanian A, Ghimire L, Hsu AY, Kambara H, Liu X, Hasegawa T, Xu R, Tahir M, Yu H, Lieberman J, Luo HR. Palmitoylation of gasdermin D directs its membrane translocation and pore formation in pyroptosis. bioRxiv. 2023 Feb 21. PMID: 36865189; PMCID: PMC9980122.
  2. Liu F, Ghimire L, Balasubramanian A, Hsu AY, Zhang Z, Yu H, Ma F, Luo HR. Neutrophil-specific depletion of gasdermin D does not protect against murine sepsis. Blood. 2023 02 02; 141(5):550-554. PMID: 36332166; PMCID: PMC9936303.
    Citations:    Fields:    Translation:HumansAnimalsCells
  3. Paudel S, Ghimire L, Jin L, Jeansonne D, Jeyaseelan S. Regulation of emergency granulopoiesis during infection. Front Immunol. 2022; 13:961601. PMID: 36148240; PMCID: PMC9485265.
    Citations:    Fields:    Translation:Cells
  4. Rangasamy T, Ghimire L, Jin L, Le J, Periasamy S, Paudel S, Cai S, Jeyaseelan S. Host Defense against Klebsiella pneumoniae Pneumonia Is Augmented by Lung-Derived Mesenchymal Stem Cells. J Immunol. 2021 08 15; 207(4):1112-1127. PMID: 34341173; PMCID: PMC8355100.
    Citations: 1     Fields:    Translation:AnimalsCells
  5. Cai S, Paudel S, Jin L, Ghimire L, Taylor CM, Wakamatsu N, Bhattarai D, Jeyaseelan S. NLRP6 modulates neutrophil homeostasis in bacterial pneumonia-derived sepsis. Mucosal Immunol. 2021 05; 14(3):574-584. PMID: 33230225; PMCID: PMC8084869.
    Citations: 13     Fields:    Translation:HumansAnimalsCells
  6. Ghimire L, Jeyaseelan S. Kiss of Death: Ring Finger 216 Regulates Toll-like Receptor 8 Stability through Ubiquitination. Am J Respir Cell Mol Biol. 2020 02; 62(2):125-127. PMID: 31414897; PMCID: PMC6993538.
    Citations: 1     Fields:    Translation:Cells
  7. Ghimire L, Paudel S, Jin L, Jeyaseelan S. The NLRP6 inflammasome in health and disease. Mucosal Immunol. 2020 05; 13(3):388-398. PMID: 31988468; PMCID: PMC7493825.
    Citations: 33     Fields:    Translation:HumansAnimalsCells
  8. Paudel S, Baral P, Ghimire L, Bergeron S, Jin L, DeCorte JA, Le JT, Cai S, Jeyaseelan S. CXCL1 regulates neutrophil homeostasis in pneumonia-derived sepsis caused by Streptococcus pneumoniae serotype 3. Blood. 2019 03 21; 133(12):1335-1345. PMID: 30723078; PMCID: PMC6428667.
    Citations: 39     Fields:    Translation:AnimalsCells
  9. Paudel S, Ghimire L, Jin L, Baral P, Cai S, Jeyaseelan S. NLRC4 suppresses IL-17A-mediated neutrophil-dependent host defense through upregulation of IL-18 and induction of necroptosis during Gram-positive pneumonia. Mucosal Immunol. 2019 01; 12(1):247-257. PMID: 30279514; PMCID: PMC6301100.
    Citations: 19     Fields:    Translation:HumansAnimalsCells
  10. Ghimire L, Paudel S, Jin L, Baral P, Cai S, Jeyaseelan S. NLRP6 negatively regulates pulmonary host defense in Gram-positive bacterial infection through modulating neutrophil recruitment and function. PLoS Pathog. 2018 09; 14(9):e1007308. PMID: 30248149; PMCID: PMC6171945.
    Citations: 35     Fields:    Translation:HumansAnimalsCells
  11. Ravi Kumar S, Paudel S, Ghimire L, Bergeron S, Cai S, Zemans RL, Downey GP, Jeyaseelan S. Emerging Roles of Inflammasomes in Acute Pneumonia. Am J Respir Crit Care Med. 2018 01 15; 197(2):160-171. PMID: 28930487; PMCID: PMC5768907.
    Citations: 22     Fields:    Translation:Humans
  12. Marasini BP, Baral P, Aryal P, Ghimire KR, Neupane S, Dahal N, Singh A, Ghimire L, Shrestha K. Evaluation of antibacterial activity of some traditionally used medicinal plants against human pathogenic bacteria. Biomed Res Int. 2015; 2015:265425. PMID: 25738151.
    Citations: 20     Fields:    Translation:HumansAnimalsCells
  13. Ghimire L, Singh DK, Basnet HB, Bhattarai RK, Dhakal S, Sharma B. Prevalence, antibiogram and risk factors of thermophilic Campylobacter spp. in dressed porcine carcass of Chitwan, Nepal. BMC Microbiol. 2014 Apr 05; 14:85. PMID: 24708489.
    Citations: 9     Fields:    Translation:AnimalsCells
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.