Harvard Catalyst Profiles

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Tina Lebar, Ph.D.


Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Lebar T, Jerala R. Concatenated Coiled-Coil Tag for Highly Efficient, Small Molecule-Inducible Upregulation of Endogenous Mammalian Genes. Methods Mol Biol. 2023; 2577:197-209. PMID: 36173575.
    Citations:    Fields:    Translation:AnimalsCells
  2. Rihtar E, Lebar T, Lainšcek D, Kores K, Lešnik S, Bren U, Jerala R. Chemically inducible split protein regulators for mammalian cells. Nat Chem Biol. 2022 Sep 26. PMID: 36163385.
    Citations:    Fields:    
  3. Chao G, Wannier TM, Gutierrez C, Borders NC, Appleton E, Chadha A, Lebar T, Church GM. helixCAM: A platform for programmable cellular assembly in bacteria and human cells. Cell. 2022 Sep 15; 185(19):3551-3567.e39. PMID: 36055250; PMCID: PMC9481732.
    Citations:    Fields:    Translation:HumansCells
  4. Leben K, Strmšek Ž, Lebar T, Verbic A, Dragovan M, Omersa N, Anderluh G, Jerala R. Binding of the transcription activator-like effector augments transcriptional regulation by another transcription factor. Nucleic Acids Res. 2022 06 24; 50(11):6562-6574. PMID: 35670660; PMCID: PMC9226504.
    Citations:    Fields:    
  5. Meško M, Lebar T, Dekleva P, Jerala R, Bencina M. Engineering and Rewiring of a Calcium-Dependent Signaling Pathway. ACS Synth Biol. 2020 08 21; 9(8):2055-2065. PMID: 32643923.
    Citations: 4     Fields:    Translation:HumansAnimalsCells
  6. Lebar T, Lainšcek D, Merljak E, Aupic J, Jerala R. A tunable orthogonal coiled-coil interaction toolbox for engineering mammalian cells. Nat Chem Biol. 2020 05; 16(5):513-519. PMID: 31907374.
    Citations: 17     Fields:    Translation:HumansAnimalsCells
  7. Forstneric V, Oven I, Ogorevc J, Lainšcek D, Praznik A, Lebar T, Jerala R, Horvat S. CRISPRa-mediated FOXP3 gene upregulation in mammalian cells. Cell Biosci. 2019; 9:93. PMID: 31832140; PMCID: PMC6873431.
    Citations: 11     
  8. Fink T, Lonzaric J, Praznik A, Plaper T, Merljak E, Leben K, Jerala N, Lebar T, Strmšek Ž, Lapenta F, Bencina M, Jerala R. Design of fast proteolysis-based signaling and logic circuits in mammalian cells. Nat Chem Biol. 2019 02; 15(2):115-122. PMID: 30531965.
    Citations: 34     Fields:    Translation:HumansAnimalsCells
  9. Lebar T, Verbic A, Ljubetic A, Jerala R. Polarized displacement by transcription activator-like effectors for regulatory circuits. Nat Chem Biol. 2019 01; 15(1):80-87. PMID: 30455466.
    Citations: 5     Fields:    Translation:HumansCells
  10. Lebar T, Jerala R. Designed Transcriptional Regulation in Mammalian Cells Based on TALE- and CRISPR/dCas9. Methods Mol Biol. 2018; 1772:191-203. PMID: 29754229.
    Citations: 2     Fields:    Translation:HumansAnimalsCells
  11. Lainšcek D, Lebar T, Jerala R. Transcription activator-like effector-mediated regulation of gene expression based on the inducible packaging and delivery via designed extracellular vesicles. Biochem Biophys Res Commun. 2017 02 26; 484(1):15-20. PMID: 28111345.
    Citations:    Fields:    Translation:HumansCells
  12. Lebar T, Jerala R. Benchmarking of TALE- and CRISPR/dCas9-Based Transcriptional Regulators in Mammalian Cells for the Construction of Synthetic Genetic Circuits. ACS Synth Biol. 2016 10 21; 5(10):1050-1058. PMID: 27344932.
    Citations: 11     Fields:    Translation:HumansAnimalsCells
  13. Lonzaric J, Lebar T, Majerle A, Mancek-Keber M, Jerala R. Locked and proteolysis-based transcription activator-like effector (TALE) regulation. Nucleic Acids Res. 2016 Feb 18; 44(3):1471-81. PMID: 26748097; PMCID: PMC4756844.
    Citations: 8     Fields:    Translation:HumansCells
  14. Lebar T, Bezeljak U, Golob A, Jerala M, Kadunc L, Pirš B, Stražar M, Vucko D, Zupancic U, Bencina M, Forstneric V, Gaber R, Lonzaric J, Majerle A, Oblak A, Smole A, Jerala R. A bistable genetic switch based on designable DNA-binding domains. Nat Commun. 2014 Sep 29; 5:5007. PMID: 25264186.
    Citations: 23     Fields:    Translation:HumansCells
  15. Gaber R, Lebar T, Majerle A, Šter B, Dobnikar A, Bencina M, Jerala R. Designable DNA-binding domains enable construction of logic circuits in mammalian cells. Nat Chem Biol. 2014 Mar; 10(3):203-8. PMID: 24413461.
    Citations: 37     Fields:    Translation:HumansAnimalsCells
  16. Conrado RJ, Wu GC, Boock JT, Xu H, Chen SY, Lebar T, Turnšek J, Tomšic N, Avbelj M, Gaber R, Koprivnjak T, Mori J, Glavnik V, Vovk I, Bencina M, Hodnik V, Anderluh G, Dueber JE, Jerala R, DeLisa MP. DNA-guided assembly of biosynthetic pathways promotes improved catalytic efficiency. Nucleic Acids Res. 2012 Feb; 40(4):1879-89. PMID: 22021385.
    Citations: 72     Fields:    Translation:Cells
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.