Harvard Catalyst Profiles

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Conghui Yao, Ph.D.

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Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Weiss-Sadan T, Ge M, Hayashi M, Gohar M, Yao CH, de Groot A, Harry S, Carlin A, Fischer H, Shi L, Wei TY, Adelmann CH, Wolf K, Vornbäumen T, Dürr BR, Takahashi M, Richter M, Zhang J, Yang TY, Vijay V, Fisher DE, Hata AN, Haigis MC, Mostoslavsky R, Bardeesy N, Papagiannakopoulos T, Bar-Peled L. NRF2 activation induces NADH-reductive stress, providing a metabolic vulnerability in lung cancer. Cell Metab. 2023 Feb 22. PMID: 36841242.
    Citations:    Fields:    
  2. Zee BM, Poels KE, Yao CH, Kawabata KC, Wu G, Duy C, Jacobus WD, Senior E, Endress JE, Jambhekar A, Lovitch SB, Ma J, Dhall A, Harris IS, Blanco MA, Sykes DB, Licht JD, Weinstock DM, Melnick A, Haigis MC, Michor F, Shi Y. Combined epigenetic and metabolic treatments overcome differentiation blockade in acute myeloid leukemia. iScience. 2021 Jun 25; 24(6):102651. PMID: 34151238.
    Citations:    
  3. Ringel AE, Drijvers JM, Baker GJ, Catozzi A, García-Cañaveras JC, Gassaway BM, Miller BC, Juneja VR, Nguyen TH, Joshi S, Yao CH, Yoon H, Sage PT, LaFleur MW, Trombley JD, Jacobson CA, Maliga Z, Gygi SP, Sorger PK, Rabinowitz JD, Sharpe AH, Haigis MC. Obesity Shapes Metabolism in the Tumor Microenvironment to Suppress Anti-Tumor Immunity. Cell. 2020 12 23; 183(7):1848-1866.e26. PMID: 33301708; PMCID: PMC8064125.
    Citations: 99     Fields:    Translation:HumansAnimalsCells
  4. Drijvers JM, Gillis JE, Muijlwijk T, Nguyen TH, Gaudiano EF, Harris IS, LaFleur MW, Ringel AE, Yao CH, Kurmi K, Juneja VR, Trombley JD, Haigis MC, Sharpe AH. Pharmacologic Screening Identifies Metabolic Vulnerabilities of CD8+ T Cells. Cancer Immunol Res. 2021 02; 9(2):184-199. PMID: 33277233; PMCID: PMC7864883.
    Citations: 13     Fields:    Translation:HumansAnimalsCells
  5. Ke W, Saba JA, Yao CH, Hilzendeger MA, Drangowska-Way A, Joshi C, Mony VK, Benjamin SB, Zhang S, Locasale J, Patti GJ, Lewis N, O'Rourke EJ. Dietary serine-microbiota interaction enhances chemotherapeutic toxicity without altering drug conversion. Nat Commun. 2020 05 22; 11(1):2587. PMID: 32444616; PMCID: PMC7244588.
    Citations: 11     Fields:    Translation:AnimalsCells
  6. Chen H, Shi Z, Guo J, Chang KJ, Chen Q, Yao CH, Haigis MC, Shi Y. The human mitochondrial 12S rRNA m4C methyltransferase METTL15 is required for mitochondrial function. J Biol Chem. 2020 06 19; 295(25):8505-8513. PMID: 32371392.
    Citations: 16     Fields:    Translation:HumansCells
  7. Yao CH, Wang L, Stancliffe E, Sindelar M, Cho K, Yin W, Wang Y, Patti GJ. Dose-Response Metabolomics To Understand Biochemical Mechanisms and Off-Target Drug Effects with the TOXcms Software. Anal Chem. 2020 01 21; 92(2):1856-1864. PMID: 31804057.
    Citations: 6     Fields:    Translation:HumansCells
  8. Yao CH, Wang R, Wang Y, Kung CP, Weber JD, Patti GJ. Mitochondrial fusion supports increased oxidative phosphorylation during cell proliferation. Elife. 2019 01 29; 8. PMID: 30694178; PMCID: PMC6351101.
    Citations: 77     Fields:    Translation:HumansAnimalsCells
  9. Lam WY, Jash A, Yao CH, D'Souza L, Wong R, Nunley RM, Meares GP, Patti GJ, Bhattacharya D. Metabolic and Transcriptional Modules Independently Diversify Plasma Cell Lifespan and Function. Cell Rep. 2018 08 28; 24(9):2479-2492.e6. PMID: 30157439.
    Citations: 40     Fields:    Translation:HumansCells
  10. Yao CH, Liu GY, Wang R, Moon SH, Gross RW, Patti GJ. Identifying off-target effects of etomoxir reveals that carnitine palmitoyltransferase I is essential for cancer cell proliferation independent of ß-oxidation. PLoS Biol. 2018 03; 16(3):e2003782. PMID: 29596410; PMCID: PMC5892939.
    Citations: 65     Fields:    Translation:HumansCells
  11. Yao CH, Liu GY, Yang K, Gross RW, Patti GJ. Inaccurate quantitation of palmitate in metabolomics and isotope tracer studies due to plastics. Metabolomics. 2016 Sep; 12. PMID: 27721678.
    Citations: 20     Fields:    
  12. Leamy AK, Hasenour CM, Egnatchik RA, Trenary IA, Yao CH, Patti GJ, Shiota M, Young JD. Knockdown of triglyceride synthesis does not enhance palmitate lipotoxicity or prevent oleate-mediated rescue in rat hepatocytes. Biochim Biophys Acta. 2016 09; 1861(9 Pt A):1005-1014. PMID: 27249207; PMCID: PMC4947436.
    Citations: 11     Fields:    Translation:AnimalsCells
  13. Yao CH, Fowle-Grider R, Mahieu NG, Liu GY, Chen YJ, Wang R, Singh M, Potter GS, Gross RW, Schaefer J, Johnson SL, Patti GJ. Exogenous Fatty Acids Are the Preferred Source of Membrane Lipids in Proliferating Fibroblasts. Cell Chem Biol. 2016 04 21; 23(4):483-93. PMID: 27049668.
    Citations: 54     Fields:    Translation:HumansAnimalsCells
  14. Lei T, Dou JH, Ma ZJ, Yao CH, Liu CJ, Wang JY, Pei J. Ambipolar polymer field-effect transistors based on fluorinated isoindigo: high performance and improved ambient stability. J Am Chem Soc. 2012 Dec 12; 134(49):20025-8. PMID: 23194175.
    Citations: 6     Fields:    
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.