Harvard Catalyst Profiles

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Natalie Kofler, Ph.D.

Other Positions

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Kofler N, Grogan CM. Giving Voice to the Voiceless in Environmental Gene Editing. Hastings Cent Rep. 2021 Nov; 51 Suppl 2:S66-S73. PMID: 34905241.
    Citations:    Fields:    Translation:Humans
  2. Baylis F, Kofler N. Vaccination certificates could entrench inequality. Nature. 2021 03; 591(7851):529. PMID: 33742178.
    Citations:    Fields:    
  3. Baylis F, Kofler N. A public health ethic should inform policies on COVID-19 immunity passports. Lancet Infect Dis. 2021 04; 21(4):456. PMID: 33301726.
    Citations: 3     Fields:    Translation:HumansCellsPHPublic Health
  4. Kofler N, Baylis F. Ten reasons why immunity passports are a bad idea. Nature. 2020 05; 581(7809):379-381. PMID: 32439992.
    Citations: 35     Fields:    
  5. Chen D, Zhu X, Kofler N, Wang Y, Zhou B, Simons M. FRS2a-dependent cell fate transition during endocardial cushion morphogenesis. Dev Biol. 2020 02 01; 458(1):88-97. PMID: 31669335.
    Citations: 1     Fields:    Translation:AnimalsCells
  6. Kofler N, Naiche LA, Zimmerman LD, Kitajewski JK. Inhibition of Jagged-Specific Notch Activation Reduces Luteal Angiogenesis and Causes Luteal Hemorrhaging of Hormonally Stimulated Ovaries. ACS Pharmacol Transl Sci. 2019 Oct 11; 2(5):325-332. PMID: 32259066; PMCID: PMC7088973.
  7. Kofler N. Why were scientists silent over gene-edited babies? Nature. 2019 02; 566(7745):427. PMID: 30809071.
    Citations: 2     Fields:    Translation:Humans
  8. Kofler N. Gene drives: yelling match drowns out marginalized voices. Nature. 2019 01; 565(7737):25. PMID: 30602747.
    Citations: 1     Fields:    Translation:HumansAnimals
  9. Kofler N, Collins JP, Kuzma J, Marris E, Esvelt K, Nelson MP, Newhouse A, Rothschild LJ, Vigliotti VS, Semenov M, Jacobsen R, Dahlman JE, Prince S, Caccone A, Brown T, Schmitz OJ. Editing nature: Local roots of global governance. Science. 2018 11 02; 362(6414):527-529. PMID: 30385564.
    Citations: 13     Fields:    Translation:Animals
  10. Kraschel KL, Kofler N. Introduction. Semin Perinatol. 2018 12; 42(8):485-486. PMID: 30420295.
    Citations:    Fields:    Translation:Humans
  11. Kofler N, Kraschel KL. Treatment of heritable diseases using CRISPR: Hopes, fears, and reality. Semin Perinatol. 2018 Dec; 42(8):515-521. PMID: 30420296.
    Citations: 1     Fields:    Translation:Humans
  12. Kofler N, Corti F, Rivera-Molina F, Deng Y, Toomre D, Simons M. The Rab-effector protein RABEP2 regulates endosomal trafficking to mediate vascular endothelial growth factor receptor-2 (VEGFR2)-dependent signaling. J Biol Chem. 2018 03 30; 293(13):4805-4817. PMID: 29425100; PMCID: PMC5880142.
    Citations: 13     Fields:    Translation:AnimalsCells
  13. Kofler N, Simons M. The expanding role of neuropilin: regulation of transforming growth factor-ß and platelet-derived growth factor signaling in the vasculature. Curr Opin Hematol. 2016 May; 23(3):260-7. PMID: 26849476; PMCID: PMC4957701.
    Citations: 22     Fields:    Translation:HumansAnimalsCells
  14. Kofler NM, Cuervo H, Uh MK, Murtomäki A, Kitajewski J. Combined deficiency of Notch1 and Notch3 causes pericyte dysfunction, models CADASIL, and results in arteriovenous malformations. Sci Rep. 2015 Nov 13; 5:16449. PMID: 26563570.
    Citations: 49     Fields:    Translation:HumansAnimalsCells
  15. Volz KS, Jacobs AH, Chen HI, Poduri A, McKay AS, Riordan DP, Kofler N, Kitajewski J, Weissman I, Red-Horse K. Pericytes are progenitors for coronary artery smooth muscle. Elife. 2015 Oct 19; 4. PMID: 26479710.
    Citations: 87     Fields:    Translation:AnimalsCells
  16. Kofler NM, Simons M. Angiogenesis versus arteriogenesis: neuropilin 1 modulation of VEGF signaling. F1000Prime Rep. 2015; 7:26. PMID: 25926977; PMCID: PMC4371373.
    Citations: 27     
  17. Kangsamaksin T, Murtomaki A, Kofler NM, Cuervo H, Chaudhri RA, Tattersall IW, Rosenstiel PE, Shawber CJ, Kitajewski J. NOTCH decoys that selectively block DLL/NOTCH or JAG/NOTCH disrupt angiogenesis by unique mechanisms to inhibit tumor growth. Cancer Discov. 2015 Feb; 5(2):182-97. PMID: 25387766.
    Citations: 70     Fields:    Translation:HumansAnimalsCells
  18. Poulos MG, Guo P, Kofler NM, Pinho S, Gutkin MC, Tikhonova A, Aifantis I, Frenette PS, Kitajewski J, Rafii S, Butler JM. Endothelial Jagged-1 is necessary for homeostatic and regenerative hematopoiesis. Cell Rep. 2013 Sep 12; 4(5):1022-34. PMID: 24012753.
    Citations: 130     Fields:    Translation:AnimalsCells
  19. Kofler NM, Shawber CJ, Kangsamaksin T, Reed HO, Galatioto J, Kitajewski J. Notch signaling in developmental and tumor angiogenesis. Genes Cancer. 2011 Dec; 2(12):1106-16. PMID: 22866202.
    Citations: 60     
  20. Banks AS, Kim-Muller JY, Mastracci TL, Kofler NM, Qiang L, Haeusler RA, Jurczak MJ, Laznik D, Heinrich G, Samuel VT, Shulman GI, Papaioannou VE, Accili D. Dissociation of the glucose and lipid regulatory functions of FoxO1 by targeted knockin of acetylation-defective alleles in mice. Cell Metab. 2011 Nov 02; 14(5):587-97. PMID: 22055502.
    Citations: 45     Fields:    Translation:AnimalsCells
  21. Outtz HH, Tattersall IW, Kofler NM, Steinbach N, Kitajewski J. Notch1 controls macrophage recruitment and Notch signaling is activated at sites of endothelial cell anastomosis during retinal angiogenesis in mice. Blood. 2011 Sep 22; 118(12):3436-9. PMID: 21795743; PMCID: PMC3179407.
    Citations: 58     Fields:    Translation:AnimalsCells
  22. Schwarzer C, Kofler N, Sperk G. Up-regulation of neuropeptide Y-Y2 receptors in an animal model of temporal lobe epilepsy. Mol Pharmacol. 1998 Jan; 53(1):6-13. PMID: 9443927.
    Citations: 20     Fields:    Translation:AnimalsCells
  23. Kofler N, Ruedl C, Rieser C, Wick G, Wolf H. Oral immunization with poly-(D,L-lactide-co-glycolide) and poly-(L-lactic acid) microspheres containing pneumotropic bacterial antigens. Int Arch Allergy Immunol. 1997 Aug; 113(4):424-31. PMID: 9250588.
    Citations: 3     Fields:    Translation:AnimalsCellsPHPublic Health
  24. Kofler N, Kirchmair E, Schwarzer C, Sperk G. Altered expression of NPY-Y1 receptors in kainic acid induced epilepsy in rats. Neurosci Lett. 1997 Jul 18; 230(2):129-32. PMID: 9259481.
    Citations: 10     Fields:    Translation:AnimalsCells
  25. Kofler N, Ruedl C, Klima J, Recheis H, Böck G, Wick G, Wolf H. Preparation and characterization of poly-(D,L-lactide-co-glycolide) and poly-(L-lactic acid) microspheres with entrapped pneumotropic bacterial antigens. J Immunol Methods. 1996 Jun 10; 192(1-2):25-35. PMID: 8699019.
    Citations: 3     Fields:    Translation:Animals
  26. Ruedl C, Rieser C, Kofler N, Wick G, Wolf H. Humoral and cellular immune responses in the murine respiratory tract following oral immunization with cholera toxin or Escherichia coli heat-labile enterotoxin. Vaccine. 1996 Jun; 14(8):792-8. PMID: 8817827.
    Citations: 4     Fields:    Translation:AnimalsCells
  27. Kofler N, Wolf H. [Stimulation of synthesis of secretory immunoglobulin A in the lung by oral immunization: an approach with therapeutic relevance?]. Wien Klin Wochenschr. 1996; 108(14):432-7. PMID: 8928514.
    Citations:    Fields:    Translation:Animals
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.