Available: 11/23/20, Expires: 10/29/21
Oncolytic viruses are a new class of cancer immunotherapy but the mechanism of action and biomarkers of response are not known. This project will test the hypothesis that intracellular gene expression of specific viral machinery factors are predictive of oncolytic virus therapeutic effectiveness.
Students with an interest in evaluating genomic databases for characterizing the status of anti-viral machinery in specific cancers are wanted. The PI is Dr. Howard Kaufman who is an expert in oncolytic virus treatment of melanoma and his lab is located at MGH main campus.