Harvard Catalyst Profiles

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Chongzhao Ran, Ph.D.

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The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. S10OD028609 (RAN, CHONGZHAO) Aug 1, 2020 - Jul 31, 2021
    Upgrade and replacement of IVIS Spectrum imaging system
    Role: Principal Investigator
  2. R21AG065826 (RAN, CHONGZHAO) Mar 1, 2020 - Feb 28, 2022
    Imaging active plaques of Alzheimers disease
    Role: Principal Investigator
  3. R56AG059814 (RAN, CHONGZHAO) Sep 1, 2019 - Aug 31, 2021
    Fluorescence ocular imaging for preliminarily screening of Alzheimer's
    Role: Principal Investigator
  4. R21AG059134 (RAN, CHONGZHAO) Aug 15, 2018 - May 31, 2021
    Near infrared Fluorescence Ocular Imaging of Soluble Amyloid Beta Species
    Role: Principal Investigator
  5. R01AG055413 (RAN, CHONGZHAO) Jan 1, 2018 - Dec 31, 2022
    Near infrared fluorescence imaging of reactive oxygen species in Alzheimer's disease
    Role: Principal Investigator

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Zhu B, Yang J, Van R, Yang F, Yu Y, Yu A, Ran K, Yin K, Liang Y, Shen X, Yin W, Choi SH, Lu Y, Wang C, Shao Y, Shi L, Tanzi RE, Zhang C, Cheng Y, Zhang Z, Ran C. Epitope alteration by small molecules and applications in drug discovery. Chem Sci. 2022 Jul 13; 13(27):8104-8116. PMID: 35919434; PMCID: PMC9278120.
  2. Rai H, Gupta S, Kumar S, Yang J, Singh SK, Ran C, Modi G. Near-Infrared Fluorescent Probes as Imaging and Theranostic Modalities for Amyloid-Beta and Tau Aggregates in Alzheimer's Disease. J Med Chem. 2022 07 14; 65(13):8550-8595. PMID: 35759679.
    Citations:    Fields:    Translation:HumansAnimals
  3. Yang H, Zeng F, Luo Y, Zheng C, Ran C, Yang J. Curcumin Scaffold as a Multifunctional Tool for Alzheimer's Disease Research. Molecules. 2022 Jun 17; 27(12). PMID: 35745002; PMCID: PMC9227459.
    Citations:    Fields:    Translation:HumansCells
  4. Satalkar V, Benassi E, Mao Y, Pan X, Ran C, Chen X, Shao Y. Computational Investigation of Substituent Effects on the Fluorescence Wavelengths of Oxyluciferin Analogs. J Photochem Photobiol A Chem. 2022 Oct 01; 431. PMID: 36407037; PMCID: PMC9673899.
  5. Liang Y, Lee DYW, Zhen S, Sun H, Zhu B, Liu J, Lei D, Lin CJ, Zhang S, Jacques NA, Quinti L, Ran C, Wang C, Griciuc A, Choi SH, Dai RH, Efferth T, Tanzi RE, Zhang C. Natural medicine HLXL targets multiple pathways of amyloid-mediated neuroinflammation and immune response in treating alzheimer's disease. Phytomedicine. 2022 Sep; 104:154158. PMID: 35728383.
    Citations:    Fields:    
  6. Cheng R, Fujinaga M, Yang J, Rong J, Haider A, Ogasawara D, Van RS, Shao T, Chen Z, Zhang X, Calderon Leon ER, Zhang Y, Mori W, Kumata K, Yamasaki T, Xie L, Sun S, Wang L, Ran C, Shao Y, Cravatt B, Josephson L, Zhang MR, Liang SH. A novel monoacylglycerol lipase-targeted 18F-labeled probe for positron emission tomography imaging of brown adipose tissue in the energy network. Acta Pharmacol Sin. 2022 Nov; 43(11):3002-3010. PMID: 35513432; PMCID: PMC9622914.
    Citations:    Fields:    
  7. Oh S, Lee C, Yang W, Li A, Mukherjee A, Basan M, Ran C, Yin W, Tabin CJ, Fu D, Xie XS, Kirschner MW. Protein and lipid mass concentration measurement in tissues by stimulated Raman scattering microscopy. Proc Natl Acad Sci U S A. 2022 04 26; 119(17):e2117938119. PMID: 35452314; PMCID: PMC9169924.
    Citations:    Fields:    
  8. Wang Z, Ye J, Zhang K, Ding L, Granzier-Nakajima T, Ranasinghe JC, Xue Y, Sharma S, Biase I, Terrones M, Choi SH, Ran C, Tanzi RE, Huang SX, Zhang C, Huang S. Rapid Biomarker Screening of Alzheimer's Disease by Interpretable Machine Learning and Graphene-Assisted Raman Spectroscopy. ACS Nano. 2022 04 26; 16(4):6426-6436. PMID: 35333038.
    Citations: 1     Fields:    
  9. Shi K, Liu Y, Zhang Q, Ran CP, Hou J, Zhang Y, Wang XB. Severe Type of COVID-19: Pathogenesis, Warning Indicators and Treatment. Chin J Integr Med. 2022 Jan; 28(1):3-11. PMID: 34962616; PMCID: PMC8713541.
    Citations:    Fields:    Translation:HumansCells
  10. Haider A, Xiao Z, Xia X, Chen J, Van RS, Kuang S, Zhao C, Rong J, Shao T, Ramesh P, Aravind A, Shao Y, Ran C, Young LJ, Liang SH. Development of a triazolobenzodiazepine-based PET probe for subtype-selective vasopressin 1A receptor imaging. Pharmacol Res. 2021 11; 173:105886. PMID: 34536549; PMCID: PMC8581590.
    Citations: 1     Fields:    Translation:AnimalsCells
  11. Yang J, Zhang H, Parhat K, Xu H, Li M, Wang X, Ran C. Molecular Imaging of Brown Adipose Tissue Mass. Int J Mol Sci. 2021 Aug 30; 22(17). PMID: 34502347; PMCID: PMC8431742.
    Citations: 5     Fields:    Translation:HumansAnimals
  12. Ni R, Villois A, Dean-Ben XL, Chen Z, Vaas M, Stavrakis S, Shi G, deMello A, Ran C, Razansky D, Arosio P, Klohs J. In-vitro and in-vivo characterization of CRANAD-2 for multi-spectral optoacoustic tomography and fluorescence imaging of amyloid-beta deposits in Alzheimer mice. Photoacoustics. 2021 Sep; 23:100285. PMID: 34354924.
    Citations: 7     
  13. Zheng C, Yu Y, Kuang S, Zhu B, Zhou H, Zhang SQ, Yang J, Shi L, Ran C. ß-Amyloid Peptides Manipulate Switching Behaviors of Donor-Acceptor Stenhouse Adducts. Anal Chem. 2021 07 20; 93(28):9887-9896. PMID: 34235921.
    Citations:    Fields:    Translation:Cells
  14. Xu Y, Wang C, Wey HY, Liang Y, Chen Z, Choi SH, Ran C, Rynearson KD, Bernales DR, Koegel RE, Fiedler SA, Striar R, Wagner SL, Tanzi RE, Zhang C. Molecular imaging of Alzheimer's disease-related gamma-secretase in mice and nonhuman primates. J Exp Med. 2020 12 07; 217(12). PMID: 32936886.
    Citations: 11     Fields:    Translation:HumansAnimals
  15. Yang J, Yin W, Van R, Yin K, Wang P, Zheng C, Zhu B, Ran K, Zhang C, Kumar M, Shao Y, Ran C. Turn-on chemiluminescence probes and dual-amplification of signal for detection of amyloid beta species in vivo. Nat Commun. 2020 08 13; 11(1):4052. PMID: 32792510; PMCID: PMC7426431.
    Citations: 1     Fields:    Translation:Animals
  16. Panagia M, Yang J, Gale E, Wang H, Luptak I, Chen HH, Patel D, Croteau D, Pimentel DR, Bachschmid MM, Colucci WS, Ran C, Sosnovik DE. A novel tracer for in vivo optical imaging of fatty acid metabolism in the heart and brown adipose tissue. Sci Rep. 2020 07 08; 10(1):11209. PMID: 32641756; PMCID: PMC7343860.
    Citations:    Fields:    Translation:AnimalsCells
  17. Zeng F, Yang J, Li X, Peng K, Ran C, Xu Y, Li Y. Versatile near-infrared fluorescent probe for in vivo detection of Aß oligomers. Bioorg Med Chem. 2020 07 01; 28(13):115559. PMID: 32546301.
    Citations: 2     Fields:    Translation:HumansAnimalsCells
  18. Yang J, Zhu B, Yin W, Han Z, Zheng C, Wang P, Ran C. Differentiating Aß40 and Aß42 in amyloid plaques with a small molecule fluorescence probe. Chem Sci. 2020 May 11; 11(20):5238-5245. PMID: 34122980; PMCID: PMC8159352.
    Citations: 4     
  19. Xiao Z, Wang L, Wei J, Ran C, Liang SH, Shang J, Chen GY, Zheng C. Visible-light induced decarboxylative coupling of redox-active esters with disulfides to construct C-S bonds. Chem Commun (Camb). 2020 Apr 14; 56(30):4164-4167. PMID: 32207477.
    Citations: 1     Fields:    
  20. Ran K, Yang J, Nair AV, Zhu B, Ran C. CRANAD-28: A Robust Fluorescent Compound for Visualization of Amyloid Beta Plaques. Molecules. 2020 Feb 16; 25(4). PMID: 32079064; PMCID: PMC7070309.
    Citations: 3     Fields:    Translation:HumansAnimalsCells
  21. Yang J, Yang J, Wang H, Wang J, Xiong J, Qiao C, Ran C. An atom-economical design of PET tracer for imaging avß3 integrin via utilizing the three-in-one function of 64Copper. Chem Commun (Camb). 2020 Feb 11; 56(12):1788-1791. PMID: 31960841.
    Citations:    Fields:    Translation:HumansCells
  22. Yang J, Zeng F, Li X, Ran C, Xu Y, Li Y. Highly specific detection of Aß oligomers in early Alzheimer's disease by a near-infrared fluorescent probe with a "V-shaped" spatial conformation. Chem Commun (Camb). 2020 Jan 14; 56(4):583-586. PMID: 31830165.
    Citations: 5     Fields:    Translation:AnimalsCells
  23. Yu HJ, Zhao W, Zhou Y, Cheng GJ, Sun M, Wang L, Yu L, Liang SH, Ran C. Salen-based bifunctional chemosensor for copper (II) ions: Inhibition of copper-induced amyloid-ß aggregation. Anal Chim Acta. 2020 Feb 08; 1097:144-152. PMID: 31910954.
    Citations:    Fields:    Translation:HumansCells
  24. Lan Y, Bai P, Chen Z, Neelamegam R, Placzek MS, Wang H, Fiedler SA, Yang J, Yuan G, Qu X, Schmidt HR, Song J, Normandin MD, Ran C, Wang C. Novel radioligands for imaging sigma-1 receptor in brain using positron emission tomography (PET). Acta Pharm Sin B. 2019 Nov; 9(6):1204-1215. PMID: 31867166; PMCID: PMC6900558.
    Citations: 7     
  25. Zeng Y, Li B, Li T, Liu W, Ran C, Penson RT, Poznansky MC, Du Y, Chen H. CD90low MSCs modulate intratumoral immunity to confer antitumor activity in a mouse model of ovarian cancer. Oncotarget. 2019 Jul 09; 10(43):4479-4491. PMID: 31320999.
    Citations: 2     Fields:    
  26. Lin SY, Dan X, Du XX, Ran CL, Lu X, Ren SJ, Tang ZT, Yin LZ, He CL, Yuan ZX, Fu HL, Zhao XL, Shu G. Protective Effects of Salidroside against Carbon Tetrachloride (CCl4)-Induced Liver Injury by Initiating Mitochondria to Resist Oxidative Stress in Mice. Int J Mol Sci. 2019 Jun 28; 20(13). PMID: 31261843.
    Citations: 11     Fields:    Translation:AnimalsCells
  27. Wang L, Yang J, Wang H, Ran C, Su Y, Zhao L. A Highly Selective Turn-on Fluorescent Probe for the Detection of Aluminum and Its Application to Bio-Imaging. Sensors (Basel). 2019 May 28; 19(11). PMID: 31141876; PMCID: PMC6603591.
    Citations: 1     Fields:    
  28. Yang J, Cheng R, Fu H, Yang J, Kumar M, Lu J, Xu Y, Liang SH, Cui M, Ran C. Half-curcumin analogues as PET imaging probes for amyloid beta species. Chem Commun (Camb). 2019 Mar 21; 55(25):3630-3633. PMID: 30849141.
    Citations: 7     Fields:    Translation:Animals
  29. Li B, Ohtomo R, Thunemann M, Adams SR, Yang J, Fu B, Yaseen MA, Ran C, Polimeni JR, Boas DA, Devor A, Lo EH, Arai K, Sakadžic S. Two-photon microscopic imaging of capillary red blood cell flux in mouse brain reveals vulnerability of cerebral white matter to hypoperfusion. J Cereb Blood Flow Metab. 2020 03; 40(3):501-512. PMID: 30829101; PMCID: PMC7026840.
    Citations: 12     Fields:    Translation:AnimalsCells
  30. Zeng Y, Li B, Liang Y, Reeves PM, Qu X, Ran C, Liu Q, Callahan MV, Sluder AE, Gelfand JA, Chen H, Poznansky MC. Dual blockade of CXCL12-CXCR4 and PD-1-PD-L1 pathways prolongs survival of ovarian tumor-bearing mice by prevention of immunosuppression in the tumor microenvironment. FASEB J. 2019 05; 33(5):6596-6608. PMID: 30802149; PMCID: PMC6463916.
    Citations: 52     Fields:    Translation:AnimalsCells
  31. Yang J, Yang J, Li Y, Xu Y, Ran C. Near-infrared Fluorescence Ocular Imaging (NIRFOI) of Alzheimer's Disease. Mol Imaging Biol. 2019 02; 21(1):35-43. PMID: 29802553.
    Citations: 9     Fields:    Translation:HumansAnimals
  32. Wan Y, Liang Y, Liang F, Shen N, Shinozuka K, Yu JT, Ran C, Quan Q, Tanzi RE, Zhang C. A Curcumin Analog Reduces Levels of the Alzheimer's Disease-Associated Amyloid-ß Protein by Modulating AßPP Processing and Autophagy. J Alzheimers Dis. 2019; 72(3):761-771. PMID: 31640096.
    Citations: 9     Fields:    Translation:HumansAnimalsCells
  33. Verwer EE, Kavanagh TR, Mischler WJ, Feng Y, Takahashi K, Wang S, Shoup TM, Neelamegam R, Yang J, Guehl NJ, Ran C, Massefski W, Cui Y, El-Chemaly S, Sadow PM, Oldham WM, Kijewski MF, El Fakhri G, Normandin MD, Priolo C. [18F]Fluorocholine and [18F]Fluoroacetate PET as Imaging Biomarkers to Assess Phosphatidylcholine and Mitochondrial Metabolism in Preclinical Models of TSC and LAM. Clin Cancer Res. 2018 12 01; 24(23):5925-5938. PMID: 30054282; PMCID: PMC6816044.
    Citations: 3     Fields:    Translation:HumansAnimalsCells
  34. Zhou Y, Lu J, Ran C, Zhang J. Recent Advances in Quantitative Nuclear Medicine and Molecular Imaging. Contrast Media Mol Imaging. 2018; 2018:3613156. PMID: 30046294.
    Citations:    Fields:    Translation:Humans
  35. Cao WH, Li MH, Pan CQ, Lu Y, Zhang L, Ran CP, Wu SL, Hua WH, Liu SA, Shen G, Chang M, Liu RY, Hao HX, Hu LP, Xie Y. Quantitation of Plasmacytoid Dendritic Cells in Chronic Hepatitis B Patients with HBeAg Positivity During PEG-IFN and Entecavir Therapy. J Interferon Cytokine Res. 2018 05; 38(5):197-205. PMID: 29791282.
    Citations: 5     Fields:    Translation:HumansCells
  36. Ran C, Albrecht DS, Bredella MA, Yang J, Yang J, Liang SH, Cypess AM, Loggia ML, Atassi N, Moore A. PET Imaging of Human Brown Adipose Tissue with the TSPO Tracer [11C]PBR28. Mol Imaging Biol. 2018 04; 20(2):188-193. PMID: 28983743; PMCID: PMC6394407.
    Citations: 12     Fields:    Translation:Humans
  37. Li B, Zeng Y, Reeves PM, Ran C, Liu Q, Qu X, Liang Y, Liu Z, Yuan J, Leblanc PR, Ye Z, Sluder AE, Gelfand JA, Brauns TA, Chen H, Poznansky MC. AMD3100 Augments the Efficacy of Mesothelin-Targeted, Immune-Activating VIC-008 in Mesothelioma by Modulating Intratumoral Immunosuppression. Cancer Immunol Res. 2018 05; 6(5):539-551. PMID: 29511032.
    Citations: 17     Fields:    Translation:AnimalsCells
  38. Panagia M, Chen HH, Croteau D, Iris Chen YC, Ran C, Luptak I, Josephson L, Colucci WS, Sosnovik DE. Multiplexed Optical Imaging of Energy Substrates Reveals That Left Ventricular Hypertrophy Is Associated With Brown Adipose Tissue Activation. Circ Cardiovasc Imaging. 2018 03; 11(3):e007007. PMID: 29555834.
    Citations: 4     Fields:    Translation:Animals
  39. Krishnan HS, Bernard-Gauthier V, Placzek MS, Dahl K, Narayanaswami V, Livni E, Chen Z, Yang J, Collier TL, Ran C, Hooker JM, Liang SH, Vasdev N. Metal Protein-Attenuating Compound for PET Neuroimaging: Synthesis and Preclinical Evaluation of [11C]PBT2. Mol Pharm. 2018 02 05; 15(2):695-702. PMID: 29298483.
    Citations: 4     Fields:    Translation:HumansAnimals
  40. Zhang C, Griciuc A, Hudry E, Wan Y, Quinti L, Ward J, Forte AM, Shen X, Ran C, Elmaleh DR, Tanzi RE. Cromolyn Reduces Levels of the Alzheimer's Disease-Associated Amyloid ß-Protein by Promoting Microglial Phagocytosis. Sci Rep. 2018 01 18; 8(1):1144. PMID: 29348604.
    Citations: 24     Fields:    Translation:HumansAnimalsCells
  41. Yang J, Yang J, Ran C. Spectral Unmixing Imaging for Differentiating Brown Adipose Tissue Mass and Its Activation. Contrast Media Mol Imaging. 2018; 2018:6134186. PMID: 29531505.
    Citations: 2     Fields:    Translation:HumansAnimalsCells
  42. Yang J, Zhang X, Yuan P, Yang J, Xu Y, Grutzendler J, Shao Y, Moore A, Ran C. Oxalate-curcumin-based probe for micro- and macroimaging of reactive oxygen species in Alzheimer's disease. Proc Natl Acad Sci U S A. 2017 11 21; 114(47):12384-12389. PMID: 29109280; PMCID: PMC5703278.
    Citations: 17     Fields:    Translation:HumansAnimals
  43. Li Y, Yang J, Liu H, Yang J, Du L, Feng H, Tian Y, Cao J, Ran C. Tuning the stereo-hindrance of a curcumin scaffold for the selective imaging of the soluble forms of amyloid beta species. Chem Sci. 2017 Nov 01; 8(11):7710-7717. PMID: 29568434; PMCID: PMC5851342.
    Citations: 12     
  44. Yang J, Yang J, Wang L, Moore A, Liang SH, Ran C. Synthesis-free PET imaging of brown adipose tissue and TSPO via combination of disulfiram and 64CuCl2. Sci Rep. 2017 08 15; 7(1):8298. PMID: 28811616.
    Citations: 5     Fields:    Translation:AnimalsCells
  45. Shen S, Lim G, You Z, Ding W, Huang P, Ran C, Doheny J, Caravan P, Tate S, Hu K, Kim H, McCabe M, Huang B, Xie Z, Kwon D, Chen L, Mao J. Gut microbiota is critical for the induction of chemotherapy-induced pain. Nat Neurosci. 2017 Sep; 20(9):1213-1216. PMID: 28714953; PMCID: PMC5575957.
    Citations: 68     Fields:    Translation:AnimalsCells
  46. Yang J, Zhang X, Zhu Y, Lenczowski E, Tian Y, Yang J, Zhang C, Hardt M, Qiao C, Tanzi RE, Moore A, Ye H, Ran C. The double-edged role of copper in the fate of amyloid beta in the presence of anti-oxidants. Chem Sci. 2017 Sep 01; 8(9):6155-6164. PMID: 28989646; PMCID: PMC5627602.
    Citations: 2     
  47. Wang L, Cheng R, Fujinaga M, Yang J, Zhang Y, Hatori A, Kumata K, Yang J, Vasdev N, Du Y, Ran C, Zhang MR, Liang SH. A Facile Radiolabeling of [18F]FDPA via Spirocyclic Iodonium Ylides: Preliminary PET Imaging Studies in Preclinical Models of Neuroinflammation. J Med Chem. 2017 06 22; 60(12):5222-5227. PMID: 28530834; PMCID: PMC5576052.
    Citations: 16     Fields:    Translation:Animals
  48. Kumar AT, Carp SA, Yang J, Ross A, Medarova Z, Ran C. Fluorescence lifetime-based contrast enhancement of indocyanine green-labeled tumors. J Biomed Opt. 2017 04 01; 22(4):40501. PMID: 28397959.
    Citations: 5     Fields:    Translation:HumansAnimals
  49. Wang P, Ross A, Yoo B, Yang J, Farrar C, Ran C, Pantazopoulos P, Medarova Z, Moore A. Magnetic resonance imaging of intra-pancreatic ductal nanoparticle delivery to islet cells. Diabetes Metab Res Rev. 2017 07; 33(5). PMID: 28032446.
    Citations:    Fields:    Translation:Animals
  50. Yang J, Tu Z, Xu X, Luo J, Yan X, Ran C, Mao X, Ding K, Qiao C. Novel conjugates of endoperoxide and 4-anilinoquinazoline as potential anticancer agents. Bioorg Med Chem Lett. 2017 03 15; 27(6):1341-1345. PMID: 28236592.
    Citations: 1     Fields:    Translation:HumansCells
  51. Liu H, Yang J, Wang L, Xu Y, Zhang S, Lv J, Ran C, Li Y. Targeting ß-amyloid plaques and oligomers: development of near-IR fluorescence imaging probes. Future Med Chem. 2017 02; 9(2):179-198. PMID: 28127995.
    Citations: 4     Fields:    Translation:HumansCells
  52. Yang J, Yang J, Liang SH, Xu Y, Moore A, Ran C. Imaging hydrogen peroxide in Alzheimer's disease via cascade signal amplification. Sci Rep. 2016 10 20; 6:35613. PMID: 27762326.
    Citations: 13     Fields:    Translation:Animals
  53. Kwok SJ, Choi M, Bhayana B, Zhang X, Ran C, Yun SH. Two-photon excited photoconversion of cyanine-based dyes. Sci Rep. 2016 Mar 31; 6:23866. PMID: 27029524.
    Citations: 5     Fields:    Translation:HumansAnimalsCells
  54. Meimetis LG, Boros E, Carlson JC, Ran C, Caravan P, Weissleder R. Bioorthogonal Fluorophore Linked DFO-Technology Enabling Facile Chelator Quantification and Multimodal Imaging of Antibodies. Bioconjug Chem. 2016 Jan 20; 27(1):257-63. PMID: 26684717; PMCID: PMC4858350.
    Citations: 18     Fields:    Translation:HumansAnimals
  55. Wang L, Yui J, Wang Q, Zhang Y, Mori W, Shimoda Y, Fujinaga M, Kumata K, Yamasaki T, Hatori A, Rotstein BH, Collier TL, Ran C, Vasdev N, Zhang MR, Liang SH. Synthesis and Preliminary PET Imaging Studies of a FAAH Radiotracer ([¹¹C]MPPO) Based on a-Ketoheterocyclic Scaffold. ACS Chem Neurosci. 2016 Jan 20; 7(1):109-18. PMID: 26505525.
    Citations: 9     Fields:    Translation:Animals
  56. Zhang X, Tian Y, Zhang H, Kavishwar A, Lynes M, Brownell AL, Sun H, Tseng YH, Moore A, Ran C. Curcumin analogues as selective fluorescence imaging probes for brown adipose tissue and monitoring browning. Sci Rep. 2015 Aug 13; 5:13116. PMID: 26269357.
    Citations: 19     Fields:    Translation:AnimalsCells
  57. Zhang X, Tian Y, Zhang C, Tian X, Ross AW, Moir RD, Sun H, Tanzi RE, Moore A, Ran C. Near-infrared fluorescence molecular imaging of amyloid beta species and monitoring therapy in animal models of Alzheimer's disease. Proc Natl Acad Sci U S A. 2015 Aug 04; 112(31):9734-9. PMID: 26199414; PMCID: PMC4534214.
    Citations: 39     Fields:    Translation:HumansAnimals
  58. Patel V, Zhang X, Tautiva NA, Nyabera AN, Owa OO, Baidya M, Sung HC, Taunk PS, Abdollahi S, Charles S, Gonnella RA, Gadi N, Duong KT, Fawver JN, Ran C, Jalonen TO, Murray IV. Small molecules and Alzheimer's disease: misfolding, metabolism and imaging. Curr Alzheimer Res. 2015; 12(5):445-61. PMID: 25938871.
    Citations: 3     Fields:    Translation:HumansAnimalsCells
  59. Cheng C, Gao N, Yu C, Wang Z, Wang J, Hao E, Wei Y, Mu X, Tian Y, Ran C, Jiao L. Diversity-oriented facile access to highly fluorescent membrane-permeable benz[c,d]indole N-heteroarene BF2 dyes. Org Lett. 2015 Jan 16; 17(2):278-81. PMID: 25551331.
    Citations: 2     Fields:    Translation:Cells
  60. Tian Y, Zhang X, Li Y, Shoup TM, Teng X, Elmaleh DR, Moore A, Ran C. Crown ethers attenuate aggregation of amyloid beta of Alzheimer's disease. Chem Commun (Camb). 2014 Dec 25; 50(99):15792-5. PMID: 25372154.
    Citations: 4     Fields:    Translation:Animals
  61. Zhang X, Tian Y, Yuan P, Li Y, Yaseen MA, Grutzendler J, Moore A, Ran C. A bifunctional curcumin analogue for two-photon imaging and inhibiting crosslinking of amyloid beta in Alzheimer's disease. Chem Commun (Camb). 2014 Oct 09; 50(78):11550-3. PMID: 25134928.
    Citations: 19     Fields:    Translation:HumansAnimalsCells
  62. Zhang X, Kuo C, Moore A, Ran C. Cerenkov luminescence imaging of interscapular brown adipose tissue. J Vis Exp. 2014 Oct 07; (92):e51790. PMID: 25349986.
    Citations: 4     Fields:    Translation:Animals
  63. Zheng X, Zhang X, Kang A, Ran C, Wang G, Hao H. Thinking outside the brain for cognitive improvement: Is peripheral immunomodulation on the way? Neuropharmacology. 2015 Sep; 96(Pt A):94-104. PMID: 24978103.
    Citations: 9     Fields:    Translation:HumansAnimals
  64. Zhang X, Tian Y, Li Z, Tian X, Sun H, Liu H, Moore A, Ran C. Design and synthesis of curcumin analogues for in vivo fluorescence imaging and inhibiting copper-induced cross-linking of amyloid beta species in Alzheimer's disease. J Am Chem Soc. 2013 Nov 06; 135(44):16397-409. PMID: 24116384.
    Citations: 50     Fields:    Translation:AnimalsCells
  65. Zhang X, Kuo C, Moore A, Ran C. In vivo optical imaging of interscapular brown adipose tissue with (18)F-FDG via Cerenkov luminescence imaging. PLoS One. 2013; 8(4):e62007. PMID: 23637947.
    Citations: 23     Fields:    Translation:Animals
  66. Zhang X, Ran C. Dual Functional Small Molecule Probes as Fluorophore and Ligand for Misfolding Proteins. Curr Org Chem. 2013 Mar 01; 17(6). PMID: 24363605.
    Citations: 6     
  67. Wang P, Yigit MV, Ran C, Ross A, Wei L, Dai G, Medarova Z, Moore A. A theranostic small interfering RNA nanoprobe protects pancreatic islet grafts from adoptively transferred immune rejection. Diabetes. 2012 Dec; 61(12):3247-54. PMID: 22923469; PMCID: PMC3501867.
    Citations: 20     Fields:    Translation:HumansAnimals
  68. Ran C, Moore A. Spectral unmixing imaging of wavelength-responsive fluorescent probes: an application for the real-time report of amyloid Beta species in Alzheimer's disease. Mol Imaging Biol. 2012 Jun; 14(3):293-300. PMID: 21739354.
    Citations: 13     Fields:    Translation:Animals
  69. Ran C, Zhang Z, Hooker J, Moore A. In vivo photoactivation without "light": use of Cherenkov radiation to overcome the penetration limit of light. Mol Imaging Biol. 2012 Apr; 14(2):156-62. PMID: 21538154.
    Citations: 19     Fields:    Translation:HumansAnimalsCells
  70. Ran C, Zhao W, Moir RD, Moore A. Non-conjugated small molecule FRET for differentiating monomers from higher molecular weight amyloid beta species. PLoS One. 2011 Apr 29; 6(4):e19362. PMID: 21559413.
    Citations: 19     Fields:    Translation:HumansCells
  71. Ran C, Xu X, Raymond SB, Ferrara BJ, Neal K, Bacskai BJ, Medarova Z, Moore A. Design, synthesis, and testing of difluoroboron-derivatized curcumins as near-infrared probes for in vivo detection of amyloid-beta deposits. J Am Chem Soc. 2009 Oct 28; 131(42):15257-61. PMID: 19807070.
    Citations: 81     Fields:    Translation:AnimalsCells
  72. Ran C, Xu D, Dai Q, Penning TM, Blair IA, Harvey RG. Synthesis of 13C2-Benzo[a]pyrene and its 7,8-Dihydrodiol and 7,8-Dione Implicated as Carcinogenic Metabolites. Tetrahedron Lett. 2008 Jul 21; 49(29-30):4531-4533. PMID: 24155502.
    Citations: 7     Fields:    
  73. Ran C, Dai Q, Ruan Q, Penning TM, Blair IA, Harvey RG. Strategies for synthesis of adducts of omicron-quinone metabolites of carcinogenic polycyclic aromatic hydrocarbons with 2'-deoxyribonucleosides. J Org Chem. 2008 Feb 01; 73(3):992-1003. PMID: 18181642.
    Citations: 1     Fields:    Translation:Cells
  74. Ran C, Pantazopoulos P, Medarova Z, Moore A. Synthesis and testing of beta-cell-specific streptozotocin-derived near-infrared imaging probes. Angew Chem Int Ed Engl. 2007; 46(47):8998-9001. PMID: 17957665.
    Citations: 5     Fields:    Translation:HumansCells
  75. Zhang Y, Ran C, Zhou G, Sayre LM. Highly potent 3-pyrroline mechanism-based inhibitors of bovine plasma amine oxidase and mass spectrometric confirmation of cofactor derivatization. Bioorg Med Chem. 2007 Feb 15; 15(4):1868-77. PMID: 17150363.
    Citations: 4     Fields:    Translation:AnimalsCells
  76. Kim J, Zhang Y, Ran C, Sayre LM. Inactivation of bovine plasma amine oxidase by haloallylamines. Bioorg Med Chem. 2006 Mar 01; 14(5):1444-53. PMID: 16266805.
    Citations: 3     Fields:    Translation:AnimalsCells
  77. Ran C, Dai Q, Harvey RG. N6-Arylation of 2'-deoxyadenosine via copper-catalyzed direct coupling with aryl halides. J Org Chem. 2005 Apr 29; 70(9):3724-6. PMID: 15845015.
    Citations: 1     Fields:    Translation:Cells
  78. Dai Q, Ran C, Harvey RG. Synthesis of adducts of o-quinone metabolites of carcinogenic polycyclic aromatic hydrocarbons with 2'-deoxyribonucleosides. Org Lett. 2005 Mar 17; 7(6):999-1002. PMID: 15760123.
    Citations: 3     Fields:    Translation:Cells
  79. Harvey RG, Dai Q, Ran C, Penning TM. Synthesis of the o-quinones and other oxidized metabolites of polycyclic aromatic hydrocarbons implicated in carcinogenesis. J Org Chem. 2004 Mar 19; 69(6):2024-32. PMID: 15058949.
    Citations: 21     Fields:    Translation:Cells
  80. Liu H, Ran CZ, Xia L, Ni PZ. [Synthesis and anti alpha-adrenoceptor activity in vitro of 4-((4-((2-substitutedphenoxy)ethyl)-1-piperazinyl) methyl)- 1,2-dihydro-quinoline-2-one compounds]. Yao Xue Xue Bao. 2002 Mar; 37(3):181-5. PMID: 12579757.
    Citations:    Fields:    Translation:AnimalsCells
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.