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Shaun Deane Rawson, Ph.D.

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Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Schnell HM, Walsh RM, Rawson S, Hanna J. Chaperone-mediated assembly of the proteasome core particle - recent developments and structural insights. J Cell Sci. 2022 04 15; 135(8). PMID: 35451017; PMCID: PMC9080555.
    Citations:    Fields:    Translation:AnimalsCells
  2. Schnell HM, Ang J, Rawson S, Walsh RM, Micoogullari Y, Hanna J. Mechanism of proteasome gate modulation by assembly chaperones Pba1 and Pba2. J Biol Chem. 2022 05; 298(5):101906. PMID: 35398095; PMCID: PMC9065996.
    Citations:    Fields:    Translation:AnimalsCells
  3. Zheng W, Shen C, Wang L, Rawson S, Xie WJ, Nist-Lund C, Wu J, Shen Z, Xia S, Holt JR, Wu H, Fu TM. pH regulates potassium conductance and drives a constitutive proton current in human TMEM175. Sci Adv. 2022 Mar 25; 8(12):eabm1568. PMID: 35333573; PMCID: PMC8956256.
    Citations: 1     Fields:    
  4. Andreeva L, David L, Rawson S, Shen C, Pasricha T, Pelegrin P, Wu H. NLRP3 cages revealed by full-length mouse NLRP3 structure control pathway activation. Cell. 2021 12 22; 184(26):6299-6312.e22. PMID: 34861190; PMCID: PMC8763037.
    Citations: 12     Fields:    Translation:HumansAnimalsCells
  5. Cai Y, Zhang J, Xiao T, Lavine CL, Rawson S, Peng H, Zhu H, Anand K, Tong P, Gautam A, Lu S, Sterling SM, Walsh RM, Rits-Volloch S, Lu J, Wesemann DR, Yang W, Seaman MS, Chen B. Structural basis for enhanced infectivity and immune evasion of SARS-CoV-2 variants. Science. 2021 08 06; 373(6555):642-648. PMID: 34168070; PMCID: PMC9245151.
    Citations: 70     Fields:    Translation:HumansCells
  6. Cai Y, Zhang J, Xiao T, Lavine CL, Rawson S, Peng H, Zhu H, Anand K, Tong P, Gautam A, Lu S, Sterling SM, Walsh RM, Rits-Volloch S, Lu J, Wesemann DR, Yang W, Seaman MS, Chen B. Structural basis for enhanced infectivity and immune evasion of SARS-CoV-2 variants. bioRxiv. 2021 Apr 14. PMID: 33880477; PMCID: PMC8057242.
    Citations:    
  7. Schnell HM, Walsh RM, Rawson S, Kaur M, Bhanu MK, Tian G, Prado MA, Guerra-Moreno A, Paulo JA, Gygi SP, Roelofs J, Finley D, Hanna J. Structures of chaperone-associated assembly intermediates reveal coordinated mechanisms of proteasome biogenesis. Nat Struct Mol Biol. 2021 05; 28(5):418-425. PMID: 33846632.
    Citations: 5     Fields:    Translation:AnimalsCells
  8. Susa KJ, Rawson S, Kruse AC, Blacklow SC. Cryo-EM structure of the B cell co-receptor CD19 bound to the tetraspanin CD81. Science. 2021 01 15; 371(6526):300-305. PMID: 33446559.
    Citations: 8     Fields:    Translation:HumansCells
  9. Cai Y, Zhang J, Xiao T, Peng H, Sterling SM, Walsh RM, Rawson S, Rits-Volloch S, Chen B. Distinct conformational states of SARS-CoV-2 spike protein. Science. 2020 09 25; 369(6511):1586-1592. PMID: 32694201.
    Citations: 365     Fields:    Translation:HumansCells
  10. Tomasek D, Rawson S, Lee J, Wzorek JS, Harrison SC, Li Z, Kahne D. Structure of a nascent membrane protein as it folds on the BAM complex. Nature. 2020 07; 583(7816):473-478. PMID: 32528179; PMCID: PMC7367713.
    Citations: 37     Fields:    Translation:Cells
  11. Cai Y, Zhang J, Xiao T, Peng H, Sterling SM, Walsh RM, Rawson S, Rits-Volloch S, Chen B. Distinct conformational states of SARS-CoV-2 spike protein. bioRxiv. 2020 May 17. PMID: 32511405.
    Citations:    
  12. Madej M, White JBR, Nowakowska Z, Rawson S, Scavenius C, Enghild JJ, Bereta GP, Pothula K, Kleinekathoefer U, Baslé A, Ranson NA, Potempa J, van den Berg B. Structural and functional insights into oligopeptide acquisition by the RagAB transporter from Porphyromonas gingivalis. Nat Microbiol. 2020 08; 5(8):1016-1025. PMID: 32393857.
    Citations:    
  13. Park E, Rawson S, Li K, Kim BW, Ficarro SB, Pino GG, Sharif H, Marto JA, Jeon H, Eck MJ. Architecture of autoinhibited and active BRAF-MEK1-14-3-3 complexes. Nature. 2019 11; 575(7783):545-550. PMID: 31581174; PMCID: PMC7014971.
    Citations: 70     Fields:    Translation:HumansCells
  14. Winkler MBL, Kidmose RT, Szomek M, Thaysen K, Rawson S, Muench SP, Wüstner D, Pedersen BP. Structural Insight into Eukaryotic Sterol Transport through Niemann-Pick Type C Proteins. Cell. 2019 10 03; 179(2):485-497.e18. PMID: 31543266.
    Citations: 39     Fields:    Translation:AnimalsCells
  15. Thompson RF, Iadanza MG, Hesketh EL, Rawson S, Ranson NA. Collection, pre-processing and on-the-fly analysis of data for high-resolution, single-particle cryo-electron microscopy. Nat Protoc. 2019 01; 14(1):100-118. PMID: 30487656.
    Citations:    
  16. Agip AA, Blaza JN, Bridges HR, Viscomi C, Rawson S, Muench SP, Hirst J. Cryo-EM structures of complex I from mouse heart mitochondria in two biochemically defined states. Nat Struct Mol Biol. 2018 07; 25(7):548-556. PMID: 29915388; PMCID: PMC6054875.
    Citations: 84     Fields:    Translation:AnimalsCells
  17. Vasilca V, Sadeghpour A, Rawson S, Hawke LE, Baldwin SA, Wilkinson T, Bannister D, Postis VLG, Rappolt M, Muench SP, Jeuken LJC. Spherical-supported membranes as platforms for screening against membrane protein targets. Anal Biochem. 2018 05 15; 549:58-65. PMID: 29545094.
    Citations:    
  18. Amporndanai K, Johnson RM, O'Neill PM, Fishwick CWG, Jamson AH, Rawson S, Muench SP, Hasnain SS, Antonyuk SV. X-ray and cryo-EM structures of inhibitor-bound cytochrome bc1 complexes for structure-based drug discovery. IUCrJ. 2018 Mar 01; 5(Pt 2):200-210. PMID: 29765610.
    Citations: 11     
  19. Rawson S, Bisson C, Hurdiss DL, Fazal A, McPhillie MJ, Sedelnikova SE, Baker PJ, Rice DW, Muench SP. Elucidating the structural basis for differing enzyme inhibitor potency by cryo-EM. Proc Natl Acad Sci U S A. 2018 02 20; 115(8):1795-1800. PMID: 29434040; PMCID: PMC5828572.
    Citations: 7     Fields:    Translation:AnimalsCells
  20. Johnson RM, Rawson S, McPhillie MJ, Fishwick CWG, Muench SP. The Growing Role of Electron Microscopy in Anti-parasitic Drug Discovery. Curr Med Chem. 2018; 25(39):5279-5290. PMID: 29119913.
    Citations:    
  21. Parmar M, Rawson S, Scarff CA, Goldman A, Dafforn TR, Muench SP, Postis VLG. Using a SMALP platform to determine a sub-nm single particle cryo-EM membrane protein structure. Biochim Biophys Acta Biomembr. 2018 Feb; 1860(2):378-383. PMID: 28993151.
    Citations: 36     Fields:    Translation:Cells
  22. Rawson S, McPhillie MJ, Johnson RM, Fishwick CWG, Muench SP. The potential use of single-particle electron microscopy as a tool for structure-based inhibitor design. Acta Crystallogr D Struct Biol. 2017 Jun 01; 73(Pt 6):534-540. PMID: 28580915.
    Citations:    
  23. Rawson S, Davies S, Lippiat JD, Muench SP. The changing landscape of membrane protein structural biology through developments in electron microscopy. Mol Membr Biol. 2016 03; 33(1-2):12-22. PMID: 27608730.
    Citations:    
  24. Rawson S, Harrison MA, Muench SP. Rotating with the brakes on and other unresolved features of the vacuolar ATPase. Biochem Soc Trans. 2016 06 15; 44(3):851-5. PMID: 27284051.
    Citations:    
  25. Rawson S, Iadanza MG, Ranson NA, Muench SP. Methods to account for movement and flexibility in cryo-EM data processing. Methods. 2016 05 01; 100:35-41. PMID: 27016144.
    Citations:    
  26. Rawson S, Phillips C, Huss M, Tiburcy F, Wieczorek H, Trinick J, Harrison MA, Muench SP. Structure of the vacuolar H+-ATPase rotary motor reveals new mechanistic insights. Structure. 2015 Mar 03; 23(3):461-471. PMID: 25661654.
    Citations:    
  27. Postis V, Rawson S, Mitchell JK, Lee SC, Parslow RA, Dafforn TR, Baldwin SA, Muench SP. The use of SMALPs as a novel membrane protein scaffold for structure study by negative stain electron microscopy. Biochim Biophys Acta. 2015 Feb; 1848(2):496-501. PMID: 25450810.
    Citations:    
  28. Muench SP, Rawson S, Eyraud V, Delmas AF, Da Silva P, Phillips C, Trinick J, Harrison MA, Gressent F, Huss M. PA1b inhibitor binding to subunits c and e of the vacuolar ATPase reveals its insecticidal mechanism. J Biol Chem. 2014 Jun 06; 289(23):16399-408. PMID: 24795045.
    Citations:    
  29. Wilkinson C, McPhillie MJ, Zhou Y, Woods S, Afanador GA, Rawson S, Khaliq F, Prigge ST, Roberts CW, Rice DW, McLeod R, Fishwick CW, Muench SP. The benzimidazole based drugs show good activity against T. gondii but poor activity against its proposed enoyl reductase enzyme target. Bioorg Med Chem Lett. 2014 Feb 01; 24(3):911-6. PMID: 24398298.
    Citations:    
  30. Song CF, Papachristos K, Rawson S, Huss M, Wieczorek H, Paci E, Trinick J, Harrison MA, Muench SP. Flexibility within the rotor and stators of the vacuolar H+-ATPase. PLoS One. 2013; 8(12):e82207. PMID: 24312643.
    Citations:    
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.