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Ole Isacson, Dr.Med.Sci, M.B.

Co-Author

This page shows the publications co-authored by Ole Isacson and Xandra Breakefield.
Connection Strength

0.742
  1. Isacson O, Breakefield XO. Benefits and risks of hosting animal cells in the human brain. Nat Med. 1997 Sep; 3(9):964-9.
    View in: PubMed
    Score: 0.206
  2. Costantini LC, Fraefel C, Breakefield XO, Isacson O. Herpes simplex virus/adeno-associated virus hybrid vectors for gene transfer to neurons. Preparation and use. Methods Mol Med. 2002; 69:461-79.
    View in: PubMed
    Score: 0.069
  3. Costantini LC, Bakowska JC, Breakefield XO, Isacson O. Gene therapy in the CNS. Gene Ther. 2000 Jan; 7(2):93-109.
    View in: PubMed
    Score: 0.060
  4. Costantini LC, Jacoby DR, Wang S, Fraefel C, Breakefield XO, Isacson O. Gene transfer to the nigrostriatal system by hybrid herpes simplex virus/adeno-associated virus amplicon vectors. Hum Gene Ther. 1999 Oct 10; 10(15):2481-94.
    View in: PubMed
    Score: 0.059
  5. Isacson O, Frim DM, Galpern WR, Tatter SB, Breakefield XO, Schumacher JM. Cell-mediated delivery of neurotrophic factors and neuroprotection in the neostriatum and substantia nigra. Restor Neurol Neurosci. 1995 Jan 01; 8(1):59-61.
    View in: PubMed
    Score: 0.043
  6. Andersen JK, Frim DM, Isacson O, Beal MF, Breakefield XO. Elevation of neuronal MAO-B activity in a transgenic mouse model does not increase sensitivity to the neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP). Brain Res. 1994 Sep 05; 656(1):108-14.
    View in: PubMed
    Score: 0.042
  7. Frim DM, Uhler TA, Galpern WR, Beal MF, Breakefield XO, Isacson O. Implanted fibroblasts genetically engineered to produce brain-derived neurotrophic factor prevent 1-methyl-4-phenylpyridinium toxicity to dopaminergic neurons in the rat. Proc Natl Acad Sci U S A. 1994 May 24; 91(11):5104-8.
    View in: PubMed
    Score: 0.041
  8. Andersen JK, Frim DM, Isacson O, Breakefield XO. Herpesvirus-mediated gene delivery into the rat brain: specificity and efficiency of the neuron-specific enolase promoter. Cell Mol Neurobiol. 1993 Oct; 13(5):503-15.
    View in: PubMed
    Score: 0.039
  9. Frim DM, Simpson J, Uhler TA, Short MP, Bossi SR, Breakefield XO, Isacson O. Striatal degeneration induced by mitochondrial blockade is prevented by biologically delivered NGF. J Neurosci Res. 1993 Jul 01; 35(4):452-8.
    View in: PubMed
    Score: 0.038
  10. Frim DM, Uhler TA, Short MP, Ezzedine ZD, Klagsbrun M, Breakefield XO, Isacson O. Effects of biologically delivered NGF, BDNF and bFGF on striatal excitotoxic lesions. Neuroreport. 1993 Apr; 4(4):367-70.
    View in: PubMed
    Score: 0.038
  11. Frim DM, Short MP, Rosenberg WS, Simpson J, Breakefield XO, Isacson O. Local protective effects of nerve growth factor-secreting fibroblasts against excitotoxic lesions in the rat striatum. J Neurosurg. 1993 Feb; 78(2):267-73.
    View in: PubMed
    Score: 0.037
  12. Rosenberg WS, Breakefield XO, DeAntonio C, Isacson O. Authentic and artifactual detection of the E. coli lacZ gene product in the rat brain by histochemical methods. Brain Res Mol Brain Res. 1992 Dec; 16(3-4):311-5.
    View in: PubMed
    Score: 0.037
  13. Schumacher JM, Short MP, Hyman BT, Breakefield XO, Isacson O. Intracerebral implantation of nerve growth factor-producing fibroblasts protects striatum against neurotoxic levels of excitatory amino acids. Neuroscience. 1991; 45(3):561-70.
    View in: PubMed
    Score: 0.032
Connection Strength
The connection strength for co-authors is the sum of the scores for each of their shared publications.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.
Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.