Harvard Catalyst Profiles

Contact, publication, and social network information about Harvard faculty and fellows.

Keith Alan Johnson, M.D.

Co-Author

This page shows the publications co-authored by Keith Johnson and Aaron Schultz.
Connection Strength

7.949
  1. The cortical origin and initial spread of medial temporal tauopathy in Alzheimer's disease assessed with positron emission tomography. Sci Transl Med. 2021 01 20; 13(577).
    View in: PubMed
    Score: 0.236
  2. Resting-state functional connectivity and amyloid burden influence longitudinal cortical thinning in the default mode network in preclinical Alzheimer's disease. Neuroimage Clin. 2020; 28:102407.
    View in: PubMed
    Score: 0.230
  3. Inferior temporal tau is associated with accelerated prospective cortical thinning in clinically normal older adults. Neuroimage. 2020 10 15; 220:116991.
    View in: PubMed
    Score: 0.226
  4. The presubiculum links incipient amyloid and tau pathology to memory function in older persons. Neurology. 2020 05 05; 94(18):e1916-e1928.
    View in: PubMed
    Score: 0.223
  5. Longitudinal degradation of the default/salience network axis in symptomatic individuals with elevated amyloid burden. Neuroimage Clin. 2020; 26:102052.
    View in: PubMed
    Score: 0.216
  6. Amyloid imaging of dutch-type hereditary cerebral amyloid angiopathy carriers. Ann Neurol. 2019 10; 86(4):616-625.
    View in: PubMed
    Score: 0.213
  7. Association of Amyloid and Tau With Cognition in Preclinical Alzheimer Disease: A Longitudinal Study. JAMA Neurol. 2019 Aug 01; 76(8):915-924.
    View in: PubMed
    Score: 0.213
  8. The impact of amyloid-beta and tau on prospective cognitive decline in older individuals. Ann Neurol. 2019 02; 85(2):181-193.
    View in: PubMed
    Score: 0.205
  9. Regional Tau Correlates of Instrumental Activities of Daily Living and Apathy in Mild Cognitive Impairment and Alzheimer's Disease Dementia. J Alzheimers Dis. 2019; 67(2):757-768.
    View in: PubMed
    Score: 0.204
  10. Nonlinear Distributional Mapping (NoDiM) for harmonization across amyloid-PET radiotracers. Neuroimage. 2019 02 01; 186:446-454.
    View in: PubMed
    Score: 0.203
  11. Association Between Amyloid and Tau Accumulation in Young Adults With Autosomal Dominant Alzheimer Disease. JAMA Neurol. 2018 05 01; 75(5):548-556.
    View in: PubMed
    Score: 0.195
  12. Structural tract alterations predict downstream tau accumulation in amyloid-positive older individuals. Nat Neurosci. 2018 03; 21(3):424-431.
    View in: PubMed
    Score: 0.192
  13. 18F-Flortaucipir Binding in Choroid Plexus: Related to Race and Hippocampus Signal. J Alzheimers Dis. 2018; 62(4):1691-1702.
    View in: PubMed
    Score: 0.191
  14. Hierarchical Organization of Tau and Amyloid Deposits in the Cerebral Cortex. JAMA Neurol. 2017 07 01; 74(7):813-820.
    View in: PubMed
    Score: 0.184
  15. The association between tau PET and retrospective cortical thinning in clinically normal elderly. Neuroimage. 2017 08 15; 157:612-622.
    View in: PubMed
    Score: 0.183
  16. Fluorodeoxyglucose metabolism associated with tau-amyloid interaction predicts memory decline. Ann Neurol. 2017 Apr; 81(4):583-596.
    View in: PubMed
    Score: 0.181
  17. Phases of Hyperconnectivity and Hypoconnectivity in the Default Mode and Salience Networks Track with Amyloid and Tau in Clinically Normal Individuals. J Neurosci. 2017 04 19; 37(16):4323-4331.
    View in: PubMed
    Score: 0.181
  18. Tau Positron Emission Tomographic Imaging in the Lewy Body Diseases. JAMA Neurol. 2016 Nov 01; 73(11):1334-1341.
    View in: PubMed
    Score: 0.176
  19. Temporal T807 binding correlates with CSF tau and phospho-tau in normal elderly. Neurology. 2016 Aug 30; 87(9):920-6.
    View in: PubMed
    Score: 0.173
  20. In Vivo Tau, Amyloid, and Gray Matter Profiles in the Aging Brain. J Neurosci. 2016 07 13; 36(28):7364-74.
    View in: PubMed
    Score: 0.172
  21. Decreased hippocampal metabolism in high-amyloid mild cognitive impairment. Alzheimers Dement. 2016 12; 12(12):1288-1296.
    View in: PubMed
    Score: 0.172
  22. Different partial volume correction methods lead to different conclusions: An (18)F-FDG-PET study of aging. Neuroimage. 2016 05 15; 132:334-343.
    View in: PubMed
    Score: 0.168
  23. Tau positron emission tomographic imaging in aging and early Alzheimer disease. Ann Neurol. 2016 Jan; 79(1):110-9.
    View in: PubMed
    Score: 0.166
  24. Cognitive activity relates to cognitive performance but not to Alzheimer disease biomarkers. Neurology. 2015 Jul 07; 85(1):48-55.
    View in: PubMed
    Score: 0.160
  25. Harvard Aging Brain Study: Dataset and accessibility. Neuroimage. 2017 01; 144(Pt B):255-258.
    View in: PubMed
    Score: 0.158
  26. Unsupervised mobile cognitive testing for use in preclinical Alzheimer's disease. Alzheimers Dement (Amst). 2021; 13(1):e12243.
    View in: PubMed
    Score: 0.062
  27. Association of cortical microstructure with amyloid-ß and tau: impact on cognitive decline, neurodegeneration, and clinical progression in older adults. Mol Psychiatry. 2021 Sep 29.
    View in: PubMed
    Score: 0.062
  28. Plasma IL-12/IFN-? axis predicts cognitive trajectories in cognitively unimpaired older adults. Alzheimers Dement. 2021 Jun 23.
    View in: PubMed
    Score: 0.061
  29. Comparing PET and MRI Biomarkers Predicting Cognitive Decline in Preclinical Alzheimer Disease. Neurology. 2021 May 05.
    View in: PubMed
    Score: 0.060
  30. 18F-AV-1451 positron emission tomography in neuropathological substrates of corticobasal syndrome. Brain. 2021 02 12; 144(1):266-277.
    View in: PubMed
    Score: 0.059
  31. Longitudinal amyloid and tau accumulation in autosomal dominant Alzheimer's disease: findings from the Colombia-Boston (COLBOS) biomarker study. Alzheimers Res Ther. 2021 01 15; 13(1):27.
    View in: PubMed
    Score: 0.059
  32. Diminished Learning Over Repeated Exposures (LORE) in preclinical Alzheimer's disease. Alzheimers Dement (Amst). 2020; 12(1):e12132.
    View in: PubMed
    Score: 0.059
  33. Plasma N-terminal tau fragment levels predict future cognitive decline and neurodegeneration in healthy elderly individuals. Nat Commun. 2020 11 27; 11(1):6024.
    View in: PubMed
    Score: 0.058
  34. Defining the Lowest Threshold for Amyloid-PET to Predict Future Cognitive Decline and Amyloid Accumulation. Neurology. 2021 01 26; 96(4):e619-e631.
    View in: PubMed
    Score: 0.058
  35. Decline in cognitively complex everyday activities accelerates along the Alzheimer's disease continuum. Alzheimers Res Ther. 2020 10 29; 12(1):138.
    View in: PubMed
    Score: 0.058
  36. The neurophysiology and seizure outcomes of late onset unexplained epilepsy. Clin Neurophysiol. 2020 11; 131(11):2667-2672.
    View in: PubMed
    Score: 0.058
  37. Sex Mediates Relationships Between Regional Tau Pathology and Cognitive Decline. Ann Neurol. 2020 11; 88(5):921-932.
    View in: PubMed
    Score: 0.057
  38. Multiple markers contribute to risk of progression from normal to mild cognitive impairment. Neuroimage Clin. 2020; 28:102400.
    View in: PubMed
    Score: 0.057
  39. Visual short-term memory relates to tau and amyloid burdens in preclinical autosomal dominant Alzheimer's disease. Alzheimers Res Ther. 2020 08 21; 12(1):99.
    View in: PubMed
    Score: 0.057
  40. Associative memory and in vivo brain pathology in asymptomatic presenilin-1 E280A carriers. Neurology. 2020 09 08; 95(10):e1312-e1321.
    View in: PubMed
    Score: 0.057
  41. Functional and Pathological Correlates of Judgments of Learning in Cognitively Unimpaired Older Adults. Cereb Cortex. 2020 03 14; 30(3):1974-1983.
    View in: PubMed
    Score: 0.056
  42. Amyloid-beta burden predicts prospective decline in body mass index in clinically normal adults. Neurobiol Aging. 2020 09; 93:124-130.
    View in: PubMed
    Score: 0.055
  43. Association of subjective cognitive decline with markers of brain pathology in preclinical autosomal dominant Alzheimer's disease. J Neurol Neurosurg Psychiatry. 2020 03; 91(3):330-332.
    View in: PubMed
    Score: 0.055
  44. Resistance to autosomal dominant Alzheimer's disease in an APOE3 Christchurch homozygote: a case report. Nat Med. 2019 11; 25(11):1680-1683.
    View in: PubMed
    Score: 0.054
  45. Associations of Physical Activity and ß-Amyloid With Longitudinal Cognition and Neurodegeneration in Clinically Normal Older Adults. JAMA Neurol. 2019 Oct 01; 76(10):1203-1210.
    View in: PubMed
    Score: 0.054
  46. Using subjective cognitive decline to identify high global amyloid in community-based samples: A cross-cohort study. Alzheimers Dement (Amst). 2019 Dec; 11:670-678.
    View in: PubMed
    Score: 0.054
  47. Anticholinergic Amnesia is Mediated by Alterations in Human Network Connectivity Architecture. Cereb Cortex. 2019 07 22; 29(8):3445-3456.
    View in: PubMed
    Score: 0.053
  48. Neuropathologic correlates of amyloid and dopamine transporter imaging in Lewy body disease. Neurology. 2019 07 30; 93(5):e476-e484.
    View in: PubMed
    Score: 0.053
  49. Visual cognition in non-amnestic Alzheimer's disease: Relations to tau, amyloid, and cortical atrophy. Neuroimage Clin. 2019; 23:101889.
    View in: PubMed
    Score: 0.053
  50. Sex Differences in the Association of Global Amyloid and Regional Tau Deposition Measured by Positron Emission Tomography in Clinically Normal Older Adults. JAMA Neurol. 2019 05 01; 76(5):542-551.
    View in: PubMed
    Score: 0.052
  51. Associations between baseline amyloid, sex, and APOE on subsequent tau accumulation in cerebrospinal fluid. Neurobiol Aging. 2019 06; 78:178-185.
    View in: PubMed
    Score: 0.052
  52. Striatal amyloid is associated with tauopathy and memory decline in familial Alzheimer's disease. Alzheimers Res Ther. 2019 02 04; 11(1):17.
    View in: PubMed
    Score: 0.051
  53. Vascular Risk and ß-Amyloid Are Synergistically Associated with Cortical Tau. Ann Neurol. 2019 02; 85(2):272-279.
    View in: PubMed
    Score: 0.051
  54. An UNC5C Allele Predicts Cognitive Decline and Hippocampal Atrophy in Clinically Normal Older Adults. J Alzheimers Dis. 2019; 68(3):1161-1170.
    View in: PubMed
    Score: 0.051
  55. Regional tau pathology and loneliness in cognitively normal older adults. Transl Psychiatry. 2018 12 18; 8(1):282.
    View in: PubMed
    Score: 0.051
  56. Tau Accumulation in Clinically Normal Older Adults Is Associated with Hippocampal Hyperactivity. J Neurosci. 2019 01 16; 39(3):548-556.
    View in: PubMed
    Score: 0.051
  57. Learnings about the complexity of extracellular tau aid development of a blood-based screen for Alzheimer's disease. Alzheimers Dement. 2019 03; 15(3):487-496.
    View in: PubMed
    Score: 0.051
  58. Interactive Associations of Vascular Risk and ß-Amyloid Burden With Cognitive Decline in Clinically Normal Elderly Individuals: Findings From the Harvard Aging Brain Study. JAMA Neurol. 2018 09 01; 75(9):1124-1131.
    View in: PubMed
    Score: 0.050
  59. Sex, amyloid, and APOE e4 and risk of cognitive decline in preclinical Alzheimer's disease: Findings from three well-characterized cohorts. Alzheimers Dement. 2018 09; 14(9):1193-1203.
    View in: PubMed
    Score: 0.049
  60. PET staging of amyloidosis using striatum. Alzheimers Dement. 2018 10; 14(10):1281-1292.
    View in: PubMed
    Score: 0.049
  61. Preferential degradation of cognitive networks differentiates Alzheimer's disease from ageing. Brain. 2018 05 01; 141(5):1486-1500.
    View in: PubMed
    Score: 0.049
  62. Region-Specific Association of Subjective Cognitive Decline With Tauopathy Independent of Global ß-Amyloid Burden. JAMA Neurol. 2017 12 01; 74(12):1455-1463.
    View in: PubMed
    Score: 0.047
  63. Interactive versus additive relationships between regional cortical thinning and amyloid burden in predicting clinical decline in mild AD and MCI individuals. Neuroimage Clin. 2018; 17:388-396.
    View in: PubMed
    Score: 0.047
  64. Flortaucipir tau PET imaging in semantic variant primary progressive aphasia. J Neurol Neurosurg Psychiatry. 2018 10; 89(10):1024-1031.
    View in: PubMed
    Score: 0.047
  65. Functional network integrity presages cognitive decline in preclinical Alzheimer disease. Neurology. 2017 Jul 04; 89(1):29-37.
    View in: PubMed
    Score: 0.046
  66. Neuroimaging markers associated with maintenance of optimal memory performance in late-life. Neuropsychologia. 2017 06; 100:164-170.
    View in: PubMed
    Score: 0.046
  67. Association of In Vivo [18F]AV-1451 Tau PET Imaging Results With Cortical Atrophy and Symptoms in Typical and Atypical Alzheimer Disease. JAMA Neurol. 2017 04 01; 74(4):427-436.
    View in: PubMed
    Score: 0.045
  68. Cued memory decline in biomarker-defined preclinical Alzheimer disease. Neurology. 2017 Apr 11; 88(15):1431-1438.
    View in: PubMed
    Score: 0.045
  69. Early and late change on the preclinical Alzheimer's cognitive composite in clinically normal older individuals with elevated amyloid ß. Alzheimers Dement. 2017 Sep; 13(9):1004-1012.
    View in: PubMed
    Score: 0.045
  70. Depressive Symptoms and Tau Accumulation in the Inferior Temporal Lobe and Entorhinal Cortex in Cognitively Normal Older Adults: A Pilot Study. J Alzheimers Dis. 2017; 59(3):975-985.
    View in: PubMed
    Score: 0.045
  71. Alzheimer's Disease Biomarkers and Future Decline in Cognitive Normal Older Adults. J Alzheimers Dis. 2017; 60(4):1451-1459.
    View in: PubMed
    Score: 0.045
  72. Epicenters of dynamic connectivity in the adaptation of the ventral visual system. Hum Brain Mapp. 2017 04; 38(4):1965-1976.
    View in: PubMed
    Score: 0.044
  73. Heterogeneity in Suspected Non-Alzheimer Disease Pathophysiology Among Clinically Normal Older Individuals. JAMA Neurol. 2016 Oct 01; 73(10):1185-1191.
    View in: PubMed
    Score: 0.044
  74. Lower Late-Life Body-Mass Index is Associated with Higher Cortical Amyloid Burden in Clinically Normal Elderly. J Alzheimers Dis. 2016 06 18; 53(3):1097-105.
    View in: PubMed
    Score: 0.043
  75. Cortical atrophy in patients with cerebral amyloid angiopathy: a case-control study. Lancet Neurol. 2016 07; 15(8):811-819.
    View in: PubMed
    Score: 0.043
  76. Biomarker validation of a decline in semantic processing in preclinical Alzheimer's disease. Neuropsychology. 2016 07; 30(5):624-30.
    View in: PubMed
    Score: 0.041
  77. Odor identification and Alzheimer disease biomarkers in clinically normal elderly. Neurology. 2015 May 26; 84(21):2153-60.
    View in: PubMed
    Score: 0.040
  78. Amyloid-ß deposition in mild cognitive impairment is associated with increased hippocampal activity, atrophy and clinical progression. Brain. 2015 Apr; 138(Pt 4):1023-35.
    View in: PubMed
    Score: 0.039
  79. Depressive Symptoms and Biomarkers of Alzheimer's Disease in Cognitively Normal Older Adults. J Alzheimers Dis. 2015; 46(1):63-73.
    View in: PubMed
    Score: 0.039
  80. Neuropsychiatric Symptoms and Functional Connectivity in Mild Cognitive Impairment. J Alzheimers Dis. 2015; 46(3):727-35.
    View in: PubMed
    Score: 0.039
  81. Apathy is associated with lower inferior temporal cortical thickness in mild cognitive impairment and normal elderly individuals. J Neuropsychiatry Clin Neurosci. 2015; 27(1):e22-7.
    View in: PubMed
    Score: 0.038
  82. Structural network alterations and neurological dysfunction in cerebral amyloid angiopathy. Brain. 2015 Jan; 138(Pt 1):179-88.
    View in: PubMed
    Score: 0.038
  83. Synergistic effect of ß-amyloid and neurodegeneration on cognitive decline in clinically normal individuals. JAMA Neurol. 2014 Nov; 71(11):1379-85.
    View in: PubMed
    Score: 0.038
  84. Multiple Brain Markers are Linked to Age-Related Variation in Cognition. Cereb Cortex. 2016 Apr; 26(4):1388-400.
    View in: PubMed
    Score: 0.038
  85. Amyloid and APOE e4 interact to influence short-term decline in preclinical Alzheimer disease. Neurology. 2014 May 20; 82(20):1760-7.
    View in: PubMed
    Score: 0.037
  86. Amyloid deposition is linked to aberrant entorhinal activity among cognitively normal older adults. J Neurosci. 2014 Apr 09; 34(15):5200-10.
    View in: PubMed
    Score: 0.037
  87. Impaired default network functional connectivity in autosomal dominant Alzheimer disease. Neurology. 2013 Aug 20; 81(8):736-44.
    View in: PubMed
    Score: 0.035
  88. Cognitive profile of amyloid burden and white matter hyperintensities in cognitively normal older adults. J Neurosci. 2012 Nov 14; 32(46):16233-42.
    View in: PubMed
    Score: 0.033
  89. Neuronal dysfunction and disconnection of cortical hubs in non-demented subjects with elevated amyloid burden. Brain. 2011 Jun; 134(Pt 6):1635-46.
    View in: PubMed
    Score: 0.030
Connection Strength
The connection strength for co-authors is the sum of the scores for each of their shared publications.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.
Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.