Harvard Catalyst Profiles

University College London UCL Queen Square Institute of Neurology, National Hospital for Neurology and Neurosurgery	Fellowship	01/2018	Functional Neurosurgery - Deep Brain Stimulation in Neurology and Psychiatry
Harvard Medical School, BIDMC-Berenson-Allen Center for Noninvasive Brain Stimulation	Fellowship	09/2020	Cognitive Behavioral Neurology - Neuromodulation in Dementia
Harvard Medical School, Hebrew Rehabilitation Center-Marcus Institute for Aging Research	Fellowship	01/2022	Geriatric Neuropsychiatry & Behavioral Neurology

Davide Balos Cappon, MS, PhD is Principal Investigator, Clinician-Scientist currently working at the Hinda and Arthur Marcus Institute for Aging Research, and a board-certified psychologist specialized in clinical neuropsychology practicing at the Deanna and Sidney Wolk Center for Memory Health at Hebrew SeniorLife (HSL).

Dr. Cappon, as a clinician-scientist, has a multidisciplinary background with specific training and expertise in clinical translational research involving device-based brain stimulation techniques such as transcranial magnetic stimulation (TMS), transcranial electrical stimulation (tES) and deep brain stimulation (DBS). He conducted numerous studies examining the mechanisms, safety, and efficacy of these novel noninvasive therapeutic approaches to improve psychiatric symptoms and cognitive functions in aging and neurodegenerative diseases.

A major focus of Dr. Cappon’s research is on making precise symptom-specific circuit-based neuromodulation therapy more accessible to older adults with cognitive and mood disorders. He has developed novel methods and procedures for the safe, remotely monitored, multi-channel application of tES to older adults in their homes (HB-tES). Dr. Cappon is now investigating the use of a personalized novel and scalable home-based neuromodulation interventions that address the undertreatment of depression and other psychiatric symptoms in the context of dementia.

At HSL, another central theme of Dr. Cappon's research is preserving and lengthening healthy aging across the lifespan. Serving on the executive committee of the HSL's Healthy Aging Initiative in collaboration with investigators from the Marcus Institute, Dr. Cappon is working on expanding our understanding of multimodal factors determining lifelong health. The initiative will identify physical and mental health markers across the lifespan and promote multimodal interventions that support health and prevent age-related cognitive decline, adopting a whole-person approach to health, aging, and well-being.

Prior to coming to Hebrew SeniorLife, Dr. Cappon was trained at the UCL's Functional Neurosurgery Unit at the National Hospital of Neurology and Neurosurgery in Queen Square London UK and has been engaged in translational research at HMS since January 2018, where he has completed Fellowships in Neuromodulation in dementia at the Berenson Allen Center-Beth Israel Deaconess Medical Center and in geriatric neuropsychiatry at the Marcus Institute for Aging Research at Hebrew Rehabilitation Center.