Harvard Catalyst Profiles

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Daniel Christopher Rabe, Ph.D.


The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. F32CA236417 (RABE, DANIEL CHRISTOPHER) Dec 24, 2019 - Dec 23, 2022
    The role of extracellular vesicles in regulating response to immunotherapy
    Role: Principal Investigator
  2. F31CA192780 (RABE, DANIEL CHRISTOPHER) Sep 29, 2015 - Sep 28, 2017
    The role of macrophages in triple-negative breast cancer invasion and metastasis
    Role: Principal Investigator

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Tessier SN, Bookstaver LD, Angpraseuth C, Stannard CJ, Marques B, Ho UK, Muzikansky A, Aldikacti B, Reátegui E, Rabe DC, Toner M, Stott SL. Isolation of intact extracellular vesicles from cryopreserved samples. PLoS One. 2021; 16(5):e0251290. PMID: 33983964.
    Citations:    Fields:    
  2. Mishra A, Dubash TD, Edd JF, Jewett MK, Garre SG, Karabacak NM, Rabe DC, Mutlu BR, Walsh JR, Kapur R, Stott SL, Maheswaran S, Haber DA, Toner M. Ultrahigh-throughput magnetic sorting of large blood volumes for epitope-agnostic isolation of circulating tumor cells. Proc Natl Acad Sci U S A. 2020 07 21; 117(29):16839-16847. PMID: 32641515.
    Citations: 8     Fields:    Translation:HumansCells
  3. Lee J, Yesilkanal AE, Wynne JP, Frankenberger C, Liu J, Yan J, Elbaz M, Rabe DC, Rustandy FD, Tiwari P, Grossman EA, Hart PC, Kang C, Sanderson SM, Andrade J, Nomura DK, Bonini MG, Locasale JW, Rosner MR. Effective breast cancer combination therapy targeting BACH1 and mitochondrial metabolism. Nature. 2019 04; 568(7751):254-258. PMID: 30842661.
    Citations: 49     Fields:    Translation:HumansAnimalsCells
  4. Bainer R, Frankenberger C, Rabe D, An G, Gilad Y, Rosner MR. Gene expression in local stroma reflects breast tumor states and predicts patient outcome. Sci Rep. 2016 12 16; 6:39240. PMID: 27982086.
    Citations: 5     Fields:    Translation:HumansAnimalsCells
  5. Kaye DR, Pinto PA, Cecchi F, Reilly J, Semerjian A, Rabe DC, Gupta G, Choyke PL, Bottaro DP. Tumor and Plasma Met Levels in Non-Metastatic Prostate Cancer. PLoS One. 2016; 11(6):e0157130. PMID: 27300295.
    Citations: 1     Fields:    Translation:Humans
  6. Shapiro GI, McCallum S, Adams LM, Sherman L, Weller S, Swann S, Keer H, Miles D, Müller T, Rabe DC, Cecchi F, Bottaro DP, LoRusso P. Erratum to: A Phase 1 dose-escalation study of the safety and pharmacokinetics of once-daily oral foretinib, a multi-kinase inhibitor, in patients with solid tumors. Invest New Drugs. 2015 Dec; 33(6):1292. PMID: 26407571.
    Citations: 1     Fields:    
  7. Frankenberger C, Rabe D, Bainer R, Sankarasharma D, Chada K, Krausz T, Gilad Y, Becker L, Rosner MR. Metastasis Suppressors Regulate the Tumor Microenvironment by Blocking Recruitment of Prometastatic Tumor-Associated Macrophages. Cancer Res. 2015 Oct 01; 75(19):4063-73. PMID: 26238785.
    Citations: 34     Fields:    Translation:HumansAnimalsCells
  8. Cecchi F, Lih CJ, Lee YH, Walsh W, Rabe DC, Williams PM, Bottaro DP. Expression array analysis of the hepatocyte growth factor invasive program. Clin Exp Metastasis. 2015 Oct; 32(7):659-76. PMID: 26231668.
    Citations: 1     Fields:    Translation:HumansAnimalsCells
  9. Shah MA, Wainberg ZA, Catenacci DV, Hochster HS, Ford J, Kunz P, Lee FC, Kallender H, Cecchi F, Rabe DC, Keer H, Martin AM, Liu Y, Gagnon R, Bonate P, Liu L, Gilmer T, Bottaro DP. Phase II study evaluating 2 dosing schedules of oral foretinib (GSK1363089), cMET/VEGFR2 inhibitor, in patients with metastatic gastric cancer. PLoS One. 2013; 8(3):e54014. PMID: 23516391.
    Citations: 77     Fields:    Translation:HumansAnimalsCTClinical Trials
  10. McKee TC, Rabe D, Bokesch HR, Grkovic T, Whitson EL, Diyabalanage T, Van Wyk AW, Marcum SR, Gardella RS, Gustafson KR, Linehan WM, McMahon JB, Bottaro DP. Inhibition of hypoxia inducible factor-2 transcription: isolation of active modulators from marine sponges. J Nat Prod. 2012 Sep 28; 75(9):1632-6. PMID: 22928967.
    Citations: 4     Fields:    Translation:HumansAnimalsCells
  11. Cecchi F, Pajalunga D, Fowler CA, Uren A, Rabe DC, Peruzzi B, Macdonald NJ, Blackman DK, Stahl SJ, Byrd RA, Bottaro DP. Targeted disruption of heparan sulfate interaction with hepatocyte and vascular endothelial growth factors blocks normal and oncogenic signaling. Cancer Cell. 2012 Aug 14; 22(2):250-62. PMID: 22897854.
    Citations: 15     Fields:    Translation:HumansAnimalsCells
  12. Cecchi F, Rabe DC, Bottaro DP. Targeting the HGF/Met signaling pathway in cancer therapy. Expert Opin Ther Targets. 2012 Jun; 16(6):553-72. PMID: 22530990.
    Citations: 75     Fields:    Translation:HumansAnimalsCells
  13. Grkovic T, Whitson EL, Rabe DC, Gardella RS, Bottaro DP, Linehan WM, McMahon JB, Gustafson KR, McKee TC. Identification and evaluation of soft coral diterpenes as inhibitors of HIF-2a induced gene expression. Bioorg Med Chem Lett. 2011 Apr 01; 21(7):2113-5. PMID: 21353547.
    Citations: 6     Fields:    Translation:Animals
  14. Cecchi F, Rabe DC, Bottaro DP. The Hepatocyte Growth Factor Receptor: Structure, Function and Pharmacological Targeting in Cancer. Curr Signal Transduct Ther. 2011; 6(2):146-151. PMID: 25197268.
    Citations: 7     
  15. Bokesch HR, Gardella RS, Rabe DC, Bottaro DP, Linehan WM, McMahon JB, McKee TC. A new hypoxia inducible factor-2 inhibitory pyrrolinone alkaloid from roots and stems of Piper sarmentosum. Chem Pharm Bull (Tokyo). 2011; 59(9):1178-9. PMID: 21881266.
    Citations: 7     Fields:    Translation:HumansAnimalsCells
  16. Cecchi F, Rabe DC, Bottaro DP. Targeting the HGF/Met signalling pathway in cancer. Eur J Cancer. 2010 May; 46(7):1260-70. PMID: 20303741.
    Citations: 83     Fields:    Translation:Humans
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.