Harvard Catalyst Profiles

Contact, publication, and social network information about Harvard faculty and fellows.

HMS faculty, help us improve the algorithms in Profiles by uploading your CV!

Sung-Hyun Moon, Ph.D.


Seoul National University, Seoul, KoreaPh.D.08/2016Radiochemistry
Seoul National University, Seoul, KoreaMS02/2005Medicinal Chemistry
Hanyang University, Seoul, KoreaBS02/2003Chemical Engineering
SRS Bursary Award (ISRS 2017)
Oral presentation Award
SRS Bursary Award (ISRS 2015)
SRS Bursary Award (TERACHEM 2014)
2013 - 2014
Brain Korea 21 Plus Scholar

Research interests;
* Development of new radiopharmaceuticals, especially PET tracers
* Development of specific targeting new compounds using medicinal chemistry based radiochemistry
* Multimodality radiopharmaceuticals; Theragnosis, PET/MR, Radioisotope/Fluorescence (not only small molecule but also nanoparticle)

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Yuan G, Dhaynaut M, Guehl NJ, Afshar S, Huynh D, Moon SH, Iyengar SM, Jain MK, Pickett JE, Kang HJ, Ondrechen MJ, El Fakhri G, Normandin MD, Brownell AL. Design, Synthesis, and Characterization of [18F]mG2P026 as a High-Contrast PET Imaging Ligand for Metabotropic Glutamate Receptor 2. J Med Chem. 2022 07 28; 65(14):9939-9954. PMID: 35802702; PMCID: PMC9434700.
    Citations:    Fields:    Translation:Animals
  2. Detmer FJ, Alpert NM, Moon SH, Dhaynaut M, Guerrero JL, Guehl NJ, Xing F, Brugarolas P, Shoup TM, Normandin MD, Pelletier-Galarneau M, El Fakhri G, Petibon Y. PET imaging of mitochondrial function in acute doxorubicin-induced cardiotoxicity: a proof-of-principle study. Sci Rep. 2022 04 12; 12(1):6122. PMID: 35414642; PMCID: PMC9005533.
    Citations:    Fields:    Translation:AnimalsCells
  3. Yuan G, Dhaynaut M, Lan Y, Guehl NJ, Huynh D, Iyengar SM, Afshar S, Jain MK, Pickett JE, Kang HJ, Wang H, Moon SH, Ondrechen MJ, Wang C, Shoup TM, El Fakhri G, Normandin MD, Brownell AL. Synthesis and Characterization of 5-(2-Fluoro-4-[11C]methoxyphenyl)-2,2-dimethyl-3,4-dihydro-2H-pyrano[2,3-b]pyridine-7-carboxamide as a PET Imaging Ligand for Metabotropic Glutamate Receptor 2. J Med Chem. 2022 02 10; 65(3):2593-2609. PMID: 35089713; PMCID: PMC9434702.
    Citations:    Fields:    Translation:Animals
  4. Yuan G, Guehl NJ, Zheng B, Qu X, Moon SH, Dhaynaut M, Shoup TM, Afshar S, Kang HJ, Zhang Z, El Fakhri G, Normandin MD, Brownell AL. Synthesis and Characterization of [18F]JNJ-46356479 as the First 18F-Labeled PET Imaging Ligand for Metabotropic Glutamate Receptor 2. Mol Imaging Biol. 2021 08; 23(4):527-536. PMID: 33559035; PMCID: PMC8277681.
    Citations: 1     Fields:    Translation:Animals
  5. Guehl NJ, Neelamegam R, Zhou YP, Moon SH, Dhaynaut M, El Fakhri G, Normandin MD, Brugarolas P. Radiochemical Synthesis and Evaluation in Non-Human Primates of 3-[11C]methoxy-4-aminopyridine: A Novel PET Tracer for Imaging Potassium Channels in the CNS. ACS Chem Neurosci. 2021 02 17; 12(4):756-765. PMID: 33539063; PMCID: PMC8060895.
    Citations: 2     Fields:    Translation:Animals
  6. Shoup TM, Griciuc A, Normandin MD, Quinti L, Walsh LV, Dhaynaut M, Moon SH, Guehl NJ, Brugarolas P, Elmaleh DR, Fakhri GE, Tanzi RE. Evaluation of Fluorinated Cromolyn Derivatives as Potential Therapeutics for Alzheimer's Disease. J Alzheimers Dis. 2021; 80(2):775-786. PMID: 33579853.
    Citations: 3     Fields:    Translation:AnimalsCells
  7. Guehl NJ, Ramos-Torres KM, Linnman C, Moon SH, Dhaynaut M, Wilks MQ, Han PK, Ma C, Neelamegam R, Zhou YP, Popko B, Correia JA, Reich DS, Fakhri GE, Herscovitch P, Normandin MD, Brugarolas P. Evaluation of the potassium channel tracer [18F]3F4AP in rhesus macaques. J Cereb Blood Flow Metab. 2021 07; 41(7):1721-1733. PMID: 33090071; PMCID: PMC8221756.
    Citations: 4     Fields:    Translation:Animals
  8. Yuan G, Shoup TM, Moon SH, Brownell AL. A concise method for fully automated radiosyntheses of [18F]JNJ-46356479 and [18F]FITM via Cu-mediated 18F-fluorination of organoboranes. RSC Adv. 2020 Jul 02; 10(42):25223-25227. PMID: 33014351; PMCID: PMC7497470.
    Citations: 2     
  9. Guehl NJ, Wooten DW, Yokell DL, Moon SH, Dhaynaut M, Katz S, Moody KA, Gharagouzloo C, Kas A, Johnson KA, El Fakhri G, Normandin MD. Evaluation of pharmacokinetic modeling strategies for in-vivo quantification of tau with the radiotracer [18F]MK6240 in human subjects. Eur J Nucl Med Mol Imaging. 2019 Sep; 46(10):2099-2111. PMID: 31332496.
    Citations: 12     Fields:    Translation:Humans
  10. Moon SH, Hong MK, Kim YJ, Lee YS, Lee DS, Chung JK, Jeong JM. Development of a Ga-68 labeled PET tracer with short linker for prostate-specific membrane antigen (PSMA) targeting. Bioorg Med Chem. 2018 05 15; 26(9):2501-2507. PMID: 29655611.
    Citations: 3     Fields:    Translation:HumansAnimalsCells
  11. Moon SH, Lee YS, Lee DS, Chung JK, Jeong JM. A study of 99mTc-sestamibi labeling condition using radio-chromatography. J Radiopharm Mol Probes. 2017; 3(1):38-43. View Publication.
  12. Moon SH, Yang BY, Kim YJ, Hong MK, Lee YS, Lee DS, Chung JK, Jeong JM. Development of a complementary PET/MR dual-modal imaging probe for targeting prostate-specific membrane antigen (PSMA). Nanomedicine. 2016 May; 12(4):871-879. PMID: 26739097.
    Citations: 18     Fields:    Translation:HumansAnimalsCells
  13. Yang BY, Moon SH, Seelam SR, Jeon MJ, Lee YS, Lee DS, Chung JK, Kim YI, Jeong JM. Development of a multimodal imaging probe by encapsulating iron oxide nanoparticles with functionalized amphiphiles for lymph node imaging. Nanomedicine (Lond). 2015 Jul; 10(12):1899-910. PMID: 26139125.
    Citations: 14     Fields:    Translation:Animals
  14. Banka VK, Moon SH, Jeong JM, Seelam SR, Lee YS, Kim YJ, Lee DS, Chung JK. Development of 4-hexadecyl-4,7-diaza-1,10-decanedithiol (HDD) kit for the preparation of the liver cancer therapeutic agent Re-188-HDD/lipiodol. Nucl Med Biol. 2015 Mar; 42(3):317-22. PMID: 25537725.
    Citations: 3     Fields:    Translation:Animals
  15. Suh YG, Kim NJ, Koo BW, Lee KO, Moon SH, Shin DH, Jung JW, Paek SM, Chang DJ, Li F, Kang HJ, Le TV, Chae YN, Shin CY, Kim MK, Lim JI, Ryu JS, Park HJ. Design, synthesis, and biological evaluation of novel constrained meta-substituted phenyl propanoic acids as peroxisome proliferator-activated receptor alpha and gamma dual agonists. J Med Chem. 2008 Oct 23; 51(20):6318-33. PMID: 18826205.
    Citations: 2     Fields:    Translation:HumansAnimalsCells
  16. Suh YG, Lee KO, Moon SH, Seo SY, Lee YS, Kim SH, Paek SM, Kim YH, Lee YS, Jeong JM, Lee SJ, Kim SG. Synthesis and anti-inflammatory effects of novel pimarane diterpenoid analogs. Bioorg Med Chem Lett. 2004 Jul 05; 14(13):3487-90. PMID: 15177458.
    Citations:    Fields:    Translation:AnimalsCells
  17. Lee KO, Park HJ, Kim YH, Seo SY, Lee YS, Moon SH, Kim NJ, Choi NS, Suh YG. CoMFA and CoMSIA 3D QSAR studies on pimarane cyclooxygenase-2 (COX-2) inhibitors. Arch Pharm Res. 2004 May; 27(5):467-70. PMID: 15202549.
    Citations:    Fields:    
Local representatives can answer questions about the Profiles website or help with editing a profile or issues with profile data. For assistance with this profile: HMS/HSDM faculty should contact contactcatalyst.harvard.edu. For faculty or fellow appointment updates and changes, please ask your appointing department to contact HMS. For fellow personal and demographic information, contact HMS Human Resources at human_resourceshms.harvard.edu. For faculty personal and demographic information, contact HMS Office for Faculty Affairs at facappthms.harvard.edu.
Moon's Networks
Click the
buttons for more information and interactive visualizations!
Concepts (105)
Co-Authors (25)
Similar People (60)
Same Department 
Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.