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Hossein Estiri, Ph.D.

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Available: 12/01/20, Expires: 11/30/22

Alzheimer's (AD) and related dementias (ADRD) are two of the most critical clinical conditions in an aging world. Our team at MGH lab of computer science has developed novel AI algorithms that are both predictive and interpretable.

You will be involved in developing portable, interpretable, and transferable AI algorithms to identify cohorts of AD patients (and ADRD subpopulations) and predicting risks of AD/ADRD using both EHR and claims data. Only very minimal background in computational methodologies is required.

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Estiri H, Strasser ZH, Murphy SN. High-throughput phenotyping with temporal sequences. J Am Med Inform Assoc. 2021 Mar 18; 28(4):772-781. PMID: 33313899.
    Citations:    Fields:    
  2. Estiri H, Strasser ZH, Murphy SN. Individualized prediction of COVID-19 adverse outcomes with MLHO. Sci Rep. 2021 03 05; 11(1):5322. PMID: 33674708.
    Citations:    Fields:    Translation:HumansPHPublic Health
  3. Estiri H, Vasey S, Murphy SN. Generative transfer learning for measuring plausibility of EHR diagnosis records. J Am Med Inform Assoc. 2021 Mar 01; 28(3):559-568. PMID: 33043366.
    Citations: 1     Fields:    
  4. Klann JG, Weber GM, Estiri H, Moal B, Avillach P, Hong C, Castro V, Maulhardt T, Tan ALM, Geva A, Beaulieu-Jones BK, Malovini A, South AM, Visweswaran S, Omenn GS, Ngiam KY, Mandl KD, Boeker M, Olson KL, Mowery DL, Morris M, Follett RW, Hanauer DA, Bellazzi R, Moore JH, Loh NW, Bell DS, Wagholikar KB, Chiovato L, Tibollo V, Rieg S, Li ALLJ, Jouhet V, Schriver E, Samayamuthu MJ, Xia Z, Hutch M, Luo Y, Kohane IS, Brat GA, Murphy SN. Validation of an Internationally Derived Patient Severity Phenotype to Support COVID-19 Analytics from Electronic Health Record Data. J Am Med Inform Assoc. 2021 Feb 10. PMID: 33566082.
    Citations: 1     Fields:    
  5. Estiri H, Strasser ZH, Klann JG, Naseri P, Wagholikar KB, Murphy SN. Predicting COVID-19 mortality with electronic medical records. NPJ Digit Med. 2021 Feb 04; 4(1):15. PMID: 33542473.
    Citations: 2     
  6. Estiri H, Strasser ZH, Klann JG, McCoy TH, Wagholikar KB, Vasey S, Castro VM, Murphy ME, Murphy SN. Transitive Sequencing Medical Records for Mining Predictive and Interpretable Temporal Representations. Patterns (N Y). 2020 Jul 10; 1(4):100051. PMID: 32835307.
    Citations: 3     
  7. Wagholikar KB, Estiri H, Murphy M, Murphy SN. Polar labeling: silver standard algorithm for training disease classifiers. Bioinformatics. 2020 05 01; 36(10):3200-3206. PMID: 32049335.
    Citations: 3     Fields:    Translation:Humans
  8. Estiri H, Klann JG, Murphy SN. A clustering approach for detecting implausible observation values in electronic health records data. BMC Med Inform Decis Mak. 2019 07 23; 19(1):142. PMID: 31337390.
    Citations: 2     Fields:    Translation:Humans
  9. Estiri H, Klann JG, Weiler SR, Alema-Mensah E, Joseph Applegate R, Lozinski G, Patibandla N, Wei K, Adams WG, Natter MD, Ofili EO, Ostasiewski B, Quarshie A, Rosenthal GE, Bernstam EV, Mandl KD, Murphy SN. A federated EHR network data completeness tracking system. J Am Med Inform Assoc. 2019 07 01; 26(7):637-645. PMID: 30925587.
    Citations: 1     Fields:    Translation:Humans
  10. Estiri H, Murphy SN. Semi-supervised encoding for outlier detection in clinical observation data. Comput Methods Programs Biomed. 2019 Nov; 181:104830. PMID: 30658851.
    Citations: 1     Fields:    Translation:Humans
  11. Estiri H, Patel CJ, Murphy SN. Informatics can help providers incorporate context into care. JAMIA Open. 2018 Jul; 1(1):3-6. PMID: 31984312.
    Citations: 4     
  12. Raisaro JL, Klann JG, Wagholikar KB, Estiri H, Hubaux JP, Murphy SN. Feasibility of Homomorphic Encryption for Sharing I2B2 Aggregate-Level Data in the Cloud. AMIA Jt Summits Transl Sci Proc. 2018; 2017:176-185. PMID: 29888067.
    Citations: 2     
  13. Estiri H, Stephens KA, Klann JG, Murphy SN. Exploring completeness in clinical data research networks with DQe-c. J Am Med Inform Assoc. 2018 01 01; 25(1):17-24. PMID: 29069394.
    Citations: 4     Fields:    Translation:Humans
  14. Estiri H, Stephens K. DQe-v: A Database-Agnostic Framework for Exploring Variability in Electronic Health Record Data Across Time and Site Location. EGEMS (Wash DC). 2017 May 10; 5(1):3. PMID: 29930954.
    Citations: 6     
  15. Kahn MG, Callahan TJ, Barnard J, Bauck AE, Brown J, Davidson BN, Estiri H, Goerg C, Holve E, Johnson SG, Liaw ST, Hamilton-Lopez M, Meeker D, Ong TC, Ryan P, Shang N, Weiskopf NG, Weng C, Zozus MN, Schilling L. A Harmonized Data Quality Assessment Terminology and Framework for the Secondary Use of Electronic Health Record Data. EGEMS (Wash DC). 2016; 4(1):1244. PMID: 27713905.
    Citations: 66     
  16. Estiri H, Lovins T, Afzalan N, Stephens KA. Applying a Participatory Design Approach to Define Objectives and Properties of a "Data Profiling" Tool for Electronic Health Data. AMIA Jt Summits Transl Sci Proc. 2016; 2016:60-7. PMID: 27570651.
    Citations: 2     
  17. Stephens KA, Anderson N, Lin CP, Estiri H. Implementing partnership-driven clinical federated electronic health record data sharing networks. Int J Med Inform. 2016 09; 93:26-33. PMID: 27435944.
    Citations: 6     Fields:    Translation:Humans
  18. Cole AM, Stephens KA, Keppel GA, Estiri H, Baldwin LM. Extracting Electronic Health Record Data in a Practice-Based Research Network: Processes to Support Translational Research across Diverse Practice Organizations. EGEMS (Wash DC). 2016; 4(2):1206. PMID: 27141519.
    Citations: 6     
  19. Stephens KA, Lee ES, Estiri H, Jung H. Examining Researcher Needs and Barriers for using Electronic Health Data for Translational Research. AMIA Jt Summits Transl Sci Proc. 2015; 2015:168-72. PMID: 26306262.
    Citations: 1     
  20. Estiri H, Chan YF, Baldwin LM, Jung H, Cole A, Stephens KA. Visualizing Anomalies in Electronic Health Record Data: The Variability Explorer Tool. AMIA Jt Summits Transl Sci Proc. 2015; 2015:56-60. PMID: 26306237.
    Citations: 3     
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.