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Steven A. Lubitz, M.D.

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Mentoring
Available: 08/19/19, Expires: 08/16/22

Atrial fibrillation is a leading cause of stroke, morbidity, and economic costs. Atrial fibrillation related strokes can be prevented using anticoagulation. However subclinical, or undiagnosed, atrial fibrillation is common and may lead to strokes. Screening may help identify individuals with subclinical atrial fibrillation and lead to stroke prevention, but the effectiveness of screening is unclear. We seek to examine how atrial fibrillation risk prediction (using clinical and genetic risk factors), and traditional and novel mobile health technologies, can improve atrial fibrillation detection and stroke prevention. The student will have access to available data including clinical and genetic data, electronic health records, and data from a previously conducted randomized clinical trial of screening for atrial fibrillation. It is expected that the student will participate in data curation, data analysis, and manuscript preparation.

Available: 08/19/19, Expires: 08/16/22

Inherited arrhythmia syndromes such as the long QT syndrome, Brugada syndrome, catecholaminergic polymorphic ventricular tachycardia, and others are collectively associated with substantial morbidity and risks of sudden cardiac arrest. The long-term clinical outcomes associated with these conditions and opportunities for risk stratification remain limited. In this project, we seek to identify individuals with inherited arrhythmia syndromes and determine which clinical factors relate to long term adverse outcomes.

The student will be responsible for assisting with developing and will work with a prospectively collected database of patients with genetic arrhythmia syndromes, identifying individuals with such conditions through electronic medical record review, ascertaining candidate risk factors of interest, and ascertaining long-term clinical outcomes. It is expected that the student will participate in data management, data analysis, and manuscript preparation.

Available: 08/17/19, Expires: 08/16/22

Cardiovascular disease is a leading cause of morbidity, mortality, and economic costs. Cardiovascular disease is also heritable, and over the past decade we and others have demonstrated reported a substantial genetic basis for forms of cardiovascular disease. Examination of the genetic basis of cardiovascular disease can lead to a better understanding of the biological mechanisms of disease, improved prediction of individuals at risk for disease and related morbidity, and identification of novel therapeutic targets. The current opportunity will focus on studying the relations between genetic factors and cardiovascular disease, with a focus on arrhythmias, heart failure, and stroke. The student will have access to large-scale biorepositories with dense phenotyping data, electronic health record data, and comprehensive genome-wide genotyping and sequence data. It is expected that the student will participate in data curation, electronic phenotype validation, data analysis, and manuscript preparation. The student will work with a team of investigators including computational biologists, epidemiologists, statisticians, and clinician investigators. The project is suitable for students with an understanding and interest in genetics / biology, and proficiency with computational analysis.


Research
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. R01HL139731 (LUBITZ, STEVEN A) Jan 15, 2018 - Dec 31, 2022
    NIH
    Genomics of Cardiac Arrhythmias
    Role: Principal Investigator
  2. K23HL114724 (LUBITZ, STEVEN A) Jun 1, 2013 - Mar 31, 2018
    NIH
    Atrial Fibrillation: Bridging genetic discovery and clinical associations
    Role: Principal Investigator

Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Khurshid S, Chen W, Singer DE, Atlas SJ, Ashburner JM, Choi JG, Hur C, Ellinor PT, McManus DD, Chhatwal J, Lubitz SA. Comparative Clinical Effectiveness of Population-Based Atrial Fibrillation Screening Using Contemporary Modalities: A Decision-Analytic Model. J Am Heart Assoc. 2021 Sep 03; e020330. PMID: 34476979.
    Citations:    Fields:    
  2. Lumbers RT, Shah S, Lin H, Czuba T, Henry A, Swerdlow DI, Mälarstig A, Andersson C, Verweij N, Holmes MV, Ärnlöv J, Svensson P, Hemingway H, Sallah N, Almgren P, Aragam KG, Asselin G, Backman JD, Biggs ML, Bloom HL, Boersma E, Brandimarto J, Brown MR, Brunner-La Rocca HP, Carey DJ, Chaffin MD, Chasman DI, Chazara O, Chen X, Chen X, Chung JH, Chutkow W, Cleland JGF, Cook JP, de Denus S, Dehghan A, Delgado GE, Denaxas S, Doney AS, Dörr M, Dudley SC, Engström G, Esko T, Fatemifar G, Felix SB, Finan C, Ford I, Fougerousse F, Fouodjio R, Ghanbari M, Ghasemi S, Giedraitis V, Giulianini F, Gottdiener JS, Gross S, Guðbjartsson DF, Gui H, Gutmann R, Haggerty CM, van der Harst P, Hedman ÅK, Helgadottir A, Hillege H, Hyde CL, Jacob J, Jukema JW, Kamanu F, Kardys I, Kavousi M, Khaw KT, Kleber ME, Køber L, Koekemoer A, Kraus B, Kuchenbaecker K, Langenberg C, Lind L, Lindgren CM, London B, Lotta LA, Lovering RC, Luan J, Magnusson P, Mahajan A, Mann D, Margulies KB, Marston NA, März W, McMurray JJV, Melander O, Melloni G, Mordi IR, Morley MP, Morris AD, Morris AP, Morrison AC, Nagle MW, Nelson CP, Newton-Cheh C, Niessner A, Niiranen T, Nowak C, O'Donoghue ML, Owens AT, Palmer CNA, Paré G, Perola M, Perreault LL, Portilla-Fernandez E, Psaty BM, Rice KM, Ridker PM, Romaine SPR, Roselli C, Rotter JI, Ruff CT, Sabatine MS, Salo P, Salomaa V, van Setten J, Shalaby AA, Smelser DT, Smith NL, Stefansson K, Stender S, Stott DJ, Sveinbjörnsson G, Tammesoo ML, Tardif JC, Taylor KD, Teder-Laving M, Teumer A, Thorgeirsson G, Thorsteinsdottir U, Torp-Pedersen C, Trompet S, Tuckwell D, Tyl B, Uitterlinden AG, Vaura F, Veluchamy A, Visscher PM, Völker U, Voors AA, Wang X, Wareham NJ, Weeke PE, Weiss R, White HD, Wiggins KL, Xing H, Yang J, Yang Y, Yerges-Armstrong LM, Yu B, Zannad F, Zhao F, Wilk JB, Holm H, Sattar N, Lubitz SA, Lanfear DE, Shah S, Dunn ME, Wells QS, Asselbergs FW, Hingorani AD, Dubé MP, Samani NJ, Lang CC, Cappola TP, Ellinor PT, Vasan RS, Smith JG. The genomics of heart failure: design and rationale of the HERMES consortium. ESC Heart Fail. 2021 Sep 03. PMID: 34480422.
    Citations:    Fields:    
  3. Foulkes AS, Selvaggi C, Shinnick D, Lumish H, Kim E, Cao T, Thaweethai T, Qian J, Lu F, Yan J, Cheng D, He W, Clerkin KJ, Madhavan MV, Meigs JB, Triant VA, Lubitz SA, Gupta A, Bassett IV, Reilly MP. Understanding the link between obesity and severe COVID-19 outcomes: Causal mediation by systemic inflammatory response. J Clin Endocrinol Metab. 2021 Sep 02. PMID: 34473294.
    Citations:    Fields:    
  4. Khurshid S, Mars N, Haggerty CM, Huang Q, Weng LC, Hartzel DN, Lunetta KL, Ashburner JM, Anderson CD, Benjamin EJ, Salomaa V, Ellinor PT, Fornwalt BK, Ripatti S, Trinquart L, Lubitz SA. Predictive Accuracy of a Clinical and Genetic Risk Model for Atrial Fibrillation. Circ Genom Precis Med. 2021 Aug 31; CIRCGEN121003355. PMID: 34463125.
    Citations:    Fields:    
  5. Khurshid S, Chen W, Bode WD, Wasfy JH, Chhatwal J, Lubitz SA. Comparative Effectiveness of Implantable Defibrillators for Asymptomatic Brugada Syndrome: A Decision-Analytic Model. J Am Heart Assoc. 2021 Aug 17; 10(16):e021144. PMID: 34387130.
    Citations:    Fields:    
  6. Kornej J, Huang Q, Preis SR, Lubitz SA, Ko D, Murabito JM, Benjamin EJ, Trinquart L. Temporal trends in cause-specific mortality among individuals with newly diagnosed atrial fibrillation in the Framingham Heart Study. BMC Med. 2021 Jul 29; 19(1):170. PMID: 34320976.
    Citations:    Fields:    
  7. Choi SH, Jurgens SJ, Haggerty CM, Hall AW, Halford JL, Morrill VN, Weng LC, Lagerman B, Mirshahi T, Pettinger M, Guo X, Lin HJ, Alonso A, Soliman EZ, Kornej J, Lin H, Moscati A, Nadkarni GN, Brody JA, Wiggins KL, Cade BE, Lee J, Austin-Tse C, Blackwell T, Chaffin MD, Lee CJ, Rehm HL, Roselli C, Redline S, Mitchell BD, Sotoodehnia N, Psaty BM, Heckbert SR, Loos RJF, Vasan RS, Benjamin EJ, Correa A, Boerwinkle E, Arking DE, Rotter JI, Rich SS, Whitsel EA, Perez M, Kooperberg C, Fornwalt BK, Lunetta KL, Ellinor PT, Lubitz SA. Rare Coding Variants Associated With Electrocardiographic Intervals Identify Monogenic Arrhythmia Susceptibility Genes: A Multi-Ancestry Analysis. Circ Genom Precis Med. 2021 Aug; 14(4):e003300. PMID: 34319147.
    Citations:    Fields:    
  8. Hsu JC, Reynolds MR, Song Y, Doros G, Lubitz SA, Gehi AK, Turakhia MP, Maddox TM. Outpatient Prescription Practices in Patients with Atrial Fibrillation (From the NCDR PINNACLE Registry). Am J Cardiol. 2021 Sep 15; 155:32-39. PMID: 34284863.
    Citations:    Fields:    
  9. Kaufman ES, Eckhardt LL, Ackerman MJ, Aziz PF, Behr ER, Cerrone M, Chung MK, Cutler MJ, Etheridge SP, Krahn AD, Lubitz SA, Perez MV, Priori SG, Roberts JD, Roden DM, Schulze-Bahr E, Schwartz PJ, Shimizu W, Shoemaker MB, Sy RW, Towbin JA, Viskin S, A M Wilde A, Zareba W. Management of Congenital Long-QT Syndrome: Commentary From the Experts. Circ Arrhythm Electrophysiol. 2021 Jul; 14(7):e009726. PMID: 34238011.
    Citations:    Fields:    
  10. Khurshid S, Weng LC, Al-Alusi MA, Halford JL, Haimovich JS, Benjamin EJ, Trinquart L, Ellinor PT, McManus DD, Lubitz SA. Accelerometer-derived physical activity and risk of atrial fibrillation. Eur Heart J. 2021 07 01; 42(25):2472-2483. PMID: 34037209.
    Citations: 1     Fields:    Translation:Humans
  11. Khurshid S, Friedman S, Pirruccello JP, Di Achille P, Diamant N, Anderson CD, Ellinor PT, Batra P, Ho JE, Philippakis AA, Lubitz SA. Deep Learning to Predict Cardiac Magnetic Resonance-Derived Left Ventricular Mass and Hypertrophy From 12-Lead ECGs. Circ Cardiovasc Imaging. 2021 Jun; 14(6):e012281. PMID: 34126762.
    Citations: 1     Fields:    
  12. Kwong AM, Blackwell TW, LeFaive J, de Andrade M, Barnard J, Barnes KC, Blangero J, Boerwinkle E, Burchard EG, Cade BE, Chasman DI, Chen H, Conomos MP, Cupples LA, Ellinor PT, Eng C, Gao Y, Guo X, Irvin MR, Kelly TN, Kim W, Kooperberg C, Lubitz SA, Mak ACY, Manichaikul AW, Mathias RA, Montasser ME, Montgomery CG, Musani S, Palmer ND, Peloso GM, Qiao D, Reiner AP, Roden DM, Shoemaker MB, Smith JA, Smith NL, Su JL, Tiwari HK, Weeks DE, Weiss ST, Scott LJ, Smith AV, Abecasis GR, Boehnke M, Kang HM. Robust, flexible, and scalable tests for Hardy-Weinberg equilibrium across diverse ancestries. Genetics. 2021 May 17; 218(1). PMID: 33720349.
    Citations:    Fields:    
  13. Qin D, Bode WD, Heist EK, Lubitz SA, Santangeli P, Ruskin J, Mansour M. Catheter Ablation for Brugada Syndrome. J Innov Card Rhythm Manag. 2021 May; 12(5):4520-4524. PMID: 34035984.
    Citations:    
  14. Lau ES, McNeill JN, Paniagua SM, Liu EE, Wang JK, Bassett IV, Selvaggi CA, Lubitz SA, Foulkes AS, Ho JE. Sex differences in inflammatory markers in patients hospitalized with COVID-19 infection: Insights from the MGH COVID-19 patient registry. PLoS One. 2021; 16(4):e0250774. PMID: 33909684.
    Citations: 1     Fields:    Translation:Humans
  15. Lubitz SA, Faranesh AZ, Atlas SJ, McManus DD, Singer DE, Pagoto S, Pantelopoulos A, Foulkes AS. Rationale and design of a large population study to validate software for the assessment of atrial fibrillation from data acquired by a consumer tracker or smartwatch: The Fitbit heart study. Am Heart J. 2021 08; 238:16-26. PMID: 33865810.
    Citations:    Fields:    Translation:HumansCTClinical Trials
  16. Natarajan P, Pampana A, Graham SE, Ruotsalainen SE, Perry JA, de Vries PS, Broome JG, Pirruccello JP, Honigberg MC, Aragam K, Wolford B, Brody JA, Antonacci-Fulton L, Arden M, Aslibekyan S, Assimes TL, Ballantyne CM, Bielak LF, Bis JC, Cade BE, Do R, Doddapaneni H, Emery LS, Hung YJ, Irvin MR, Khan AT, Lange L, Lee J, Lemaitre RN, Martin LW, Metcalf G, Montasser ME, Moon JY, Muzny D, O'Connell JR, Palmer ND, Peralta JM, Peyser PA, Stilp AM, Tsai M, Wang FF, Weeks DE, Yanek LR, Wilson JG, Abecasis G, Arnett DK, Becker LC, Blangero J, Boerwinkle E, Bowden DW, Chang YC, Chen YI, Choi WJ, Correa A, Curran JE, Daly MJ, Dutcher SK, Ellinor PT, Fornage M, Freedman BI, Gabriel S, Germer S, Gibbs RA, He J, Hveem K, Jarvik GP, Kaplan RC, Kardia SLR, Kenny E, Kim RW, Kooperberg C, Laurie CC, Lee S, Lloyd-Jones DM, Loos RJF, Lubitz SA, Mathias RA, Martinez KAV, McGarvey ST, Mitchell BD, Nickerson DA, North KE, Palotie A, Park CJ, Psaty BM, Rao DC, Redline S, Reiner AP, Seo D, Seo JS, Smith AV, Tracy RP, Vasan RS, Kathiresan S, Cupples LA, Rotter JI, Morrison AC, Rich SS, Ripatti S, Willer C, Peloso GM. Chromosome Xq23 is associated with lower atherogenic lipid concentrations and favorable cardiometabolic indices. Nat Commun. 2021 04 12; 12(1):2182. PMID: 33846329.
    Citations:    Fields:    Translation:HumansCells
  17. Stiles MK, Wilde AAM, Abrams DJ, Ackerman MJ, Albert CM, Behr ER, Chugh SS, Cornel MC, Gardner K, Ingles J, James CA, Juang JJ, Kääb S, Kaufman ES, Krahn AD, Lubitz SA, MacLeod H, Morillo CA, Nademanee K, Probst V, Saarel EV, Sacilotto L, Semsarian C, Sheppard MN, Shimizu W, Skinner JR, Tfelt-Hansen J, Wang DW. 2020 APHRS/HRS expert consensus statement on the investigation of decedents with sudden unexplained death and patients with sudden cardiac arrest, and of their families. J Arrhythm. 2021 Jun; 37(3):481-534. PMID: 34141003.
    Citations:    
  18. Bick AG, Weinstock JS, Nandakumar SK, Fulco CP, Bao EL, Zekavat SM, Szeto MD, Liao X, Leventhal MJ, Nasser J, Chang K, Laurie C, Burugula BB, Gibson CJ, Niroula A, Lin AE, Taub MA, Aguet F, Ardlie K, Mitchell BD, Barnes KC, Moscati A, Fornage M, Redline S, Psaty BM, Silverman EK, Weiss ST, Palmer ND, Vasan RS, Burchard EG, Kardia SLR, He J, Kaplan RC, Smith NL, Arnett DK, Schwartz DA, Correa A, de Andrade M, Guo X, Konkle BA, Custer B, Peralta JM, Gui H, Meyers DA, McGarvey ST, Chen IY, Shoemaker MB, Peyser PA, Broome JG, Gogarten SM, Wang FF, Wong Q, Montasser ME, Daya M, Kenny EE, North KE, Launer LJ, Cade BE, Bis JC, Cho MH, Lasky-Su J, Bowden DW, Cupples LA, Mak ACY, Becker LC, Smith JA, Kelly TN, Aslibekyan S, Heckbert SR, Tiwari HK, Yang IV, Heit JA, Lubitz SA, Johnsen JM, Curran JE, Wenzel SE, Weeks DE, Rao DC, Darbar D, Moon JY, Tracy RP, Buth EJ, Rafaels N, Loos RJF, Durda P, Liu Y, Hou L, Lee J, Kachroo P, Freedman BI, Levy D, Bielak LF, Hixson JE, Floyd JS, Whitsel EA, Ellinor PT, Irvin MR, Fingerlin TE, Raffield LM, Armasu SM, Wheeler MM, Sabino EC, Blangero J, Williams LK, Levy BD, Sheu WH, Roden DM, Boerwinkle E, Manson JE, Mathias RA, Desai P, Taylor KD, Johnson AD, Auer PL, Kooperberg C, Laurie CC, Blackwell TW, Smith AV, Zhao H, Lange E, Lange L, Rich SS, Rotter JI, Wilson JG, Scheet P, Kitzman JO, Lander ES, Engreitz JM, Ebert BL, Reiner AP, Jaiswal S, Abecasis G, Sankaran VG, Kathiresan S, Natarajan P. Author Correction: Inherited causes of clonal haematopoiesis in 97,691 whole genomes. Nature. 2021 Mar; 591(7851):E27. PMID: 33707633.
    Citations: 1     Fields:    
  19. Ashburner JM, Lee PR, Rivet CM, Barr Vermilya H, Lubitz SA, Zai AH. The Implementation and Acceptability of a Mobile Application for Screening for Atrial Fibrillation at Home. Telemed J E Health. 2021 Feb 22. PMID: 33606553.
    Citations:    Fields:    
  20. Khurshid S, Li X, Ashburner JM, Lipsanopoulos ATT, Lee PR, Lin AK, Ko D, Ellinor PT, Schwamm LH, Benjamin EJ, Atlas SJ, Singer DE, Anderson CD, Trinquart L, Lubitz SA. Usefulness of Rhythm Monitoring Following Acute Ischemic Stroke. Am J Cardiol. 2021 05 15; 147:44-51. PMID: 33617814.
    Citations:    Fields:    Translation:Humans
  21. Taliun D, Harris DN, Kessler MD, Carlson J, Szpiech ZA, Torres R, Taliun SAG, Corvelo A, Gogarten SM, Kang HM, Pitsillides AN, LeFaive J, Lee SB, Tian X, Browning BL, Das S, Emde AK, Clarke WE, Loesch DP, Shetty AC, Blackwell TW, Smith AV, Wong Q, Liu X, Conomos MP, Bobo DM, Aguet F, Albert C, Alonso A, Ardlie KG, Arking DE, Aslibekyan S, Auer PL, Barnard J, Barr RG, Barwick L, Becker LC, Beer RL, Benjamin EJ, Bielak LF, Blangero J, Boehnke M, Bowden DW, Brody JA, Burchard EG, Cade BE, Casella JF, Chalazan B, Chasman DI, Chen YI, Cho MH, Choi SH, Chung MK, Clish CB, Correa A, Curran JE, Custer B, Darbar D, Daya M, de Andrade M, DeMeo DL, Dutcher SK, Ellinor PT, Emery LS, Eng C, Fatkin D, Fingerlin T, Forer L, Fornage M, Franceschini N, Fuchsberger C, Fullerton SM, Germer S, Gladwin MT, Gottlieb DJ, Guo X, Hall ME, He J, Heard-Costa NL, Heckbert SR, Irvin MR, Johnsen JM, Johnson AD, Kaplan R, Kardia SLR, Kelly T, Kelly S, Kenny EE, Kiel DP, Klemmer R, Konkle BA, Kooperberg C, Köttgen A, Lange LA, Lasky-Su J, Levy D, Lin X, Lin KH, Liu C, Loos RJF, Garman L, Gerszten R, Lubitz SA, Lunetta KL, Mak ACY, Manichaikul A, Manning AK, Mathias RA, McManus DD, McGarvey ST, Meigs JB, Meyers DA, Mikulla JL, Minear MA, Mitchell BD, Mohanty S, Montasser ME, Montgomery C, Morrison AC, Murabito JM, Natale A, Natarajan P, Nelson SC, North KE, O'Connell JR, Palmer ND, Pankratz N, Peloso GM, Peyser PA, Pleiness J, Post WS, Psaty BM, Rao DC, Redline S, Reiner AP, Roden D, Rotter JI, Ruczinski I, Sarnowski C, Schoenherr S, Schwartz DA, Seo JS, Seshadri S, Sheehan VA, Sheu WH, Shoemaker MB, Smith NL, Smith JA, Sotoodehnia N, Stilp AM, Tang W, Taylor KD, Telen M, Thornton TA, Tracy RP, Van Den Berg DJ, Vasan RS, Viaud-Martinez KA, Vrieze S, Weeks DE, Weir BS, Weiss ST, Weng LC, Willer CJ, Zhang Y, Zhao X, Arnett DK, Ashley-Koch AE, Barnes KC, Boerwinkle E, Gabriel S, Gibbs R, Rice KM, Rich SS, Silverman EK, Qasba P, Gan W, Papanicolaou GJ, Nickerson DA, Browning SR, Zody MC, Zöllner S, Wilson JG, Cupples LA, Laurie CC, Jaquish CE, Hernandez RD, O'Connor TD, Abecasis GR. Sequencing of 53,831 diverse genomes from the NHLBI TOPMed Program. Nature. 2021 02; 590(7845):290-299. PMID: 33568819.
    Citations: 64     Fields:    Translation:Humans
  22. Wu P, Wang B, Lubitz SA, Benjamin EJ, Meigs JB, Dupuis J. Approximate conditional phenotype analysis based on genome wide association summary statistics. Sci Rep. 2021 01 28; 11(1):2518. PMID: 33510268.
    Citations:    Fields:    
  23. Benjamin EJ, Go AS, Desvigne-Nickens P, Anderson CD, Casadei B, Chen LY, Crijns HJGM, Freedman B, Hills MT, Healey JS, Kamel H, Kim DY, Link MS, Lopes RD, Lubitz SA, McManus DD, Noseworthy PA, Perez MV, Piccini JP, Schnabel RB, Singer DE, Tieleman RG, Turakhia MP, Van Gelder IC, Cooper LS, Al-Khatib SM. Research Priorities in Atrial Fibrillation Screening: A Report From a National Heart, Lung, and Blood Institute Virtual Workshop. Circulation. 2021 Jan 26; 143(4):372-388. PMID: 33493033.
    Citations: 3     Fields:    
  24. Marston NA, Melloni GEM, Gurmu Y, Bonaca MP, Kamanu FK, Roselli C, Lee C, Cavallari I, Giugliano RP, Scirica BM, Bhatt DL, Steg PG, Cohen M, Storey RF, Keech AC, Raz I, Mosenzon O, Braunwald E, Lubitz SA, Ellinor PT, Sabatine MS, Ruff CT. Genetic Risk Score to Identify Risk of Venous Thromboembolism in Patients With Cardiometabolic Disease. Circ Genom Precis Med. 2021 02; 14(1):e003006. PMID: 33434447.
    Citations:    Fields:    
  25. Nauffal V, Trinquart L, Osho A, Sundt TM, Lubitz SA, Ellinor PT. Non-Vitamin K Antagonist Oral Anticoagulant vs Warfarin for Post Cardiac Surgery Atrial Fibrillation. Ann Thorac Surg. 2021 Jan 10. PMID: 33440173.
    Citations:    Fields:    
  26. Orkaby AR, Kornej J, Lubitz SA, McManus DD, Travison TG, Sherer JA, Trinquart L, Murabito JM, Benjamin EJ, Preis SR. Association Between Frailty and Atrial Fibrillation in Older Adults: The Framingham Heart Study Offspring Cohort. J Am Heart Assoc. 2021 01 05; 10(1):e018557. PMID: 33372538.
    Citations: 1     Fields:    
  27. McNeill JN, Lau ES, Paniagua SM, Liu EE, Wang JK, Bassett IV, Selvaggi CA, Lubitz SA, Foulkes AS, Ho JE. The role of obesity in inflammatory markers in COVID-19 patients. Obes Res Clin Pract. 2021 Jan-Feb; 15(1):96-99. PMID: 33390322.
    Citations: 1     Fields:    Translation:Humans
  28. Bassett IV, Triant VA, Bunda BA, Selvaggi CA, Shinnick DJ, He W, Lu F, Porneala BC, Cao T, Lubitz SA, Meigs JB, Hsu J, Foulkes AS. Massachusetts general hospital Covid-19 registry reveals two distinct populations of hospitalized patients by race and ethnicity. PLoS One. 2020; 15(12):e0244270. PMID: 33351826.
    Citations: 5     Fields:    Translation:Humans
  29. Nielsen JB, Rom O, Surakka I, Graham SE, Zhou W, Roychowdhury T, Fritsche LG, Gagliano Taliun SA, Sidore C, Liu Y, Gabrielsen ME, Skogholt AH, Wolford B, Overton W, Zhao Y, Chen J, Zhang H, Hornsby WE, Acheampong A, Grooms A, Schaefer A, Zajac GJM, Villacorta L, Zhang J, Brumpton B, Løset M, Rai V, Lundegaard PR, Olesen MS, Taylor KD, Palmer ND, Chen YD, Choi SH, Lubitz SA, Ellinor PT, Barnes KC, Daya M, Rafaels N, Weiss ST, Lasky-Su J, Tracy RP, Vasan RS, Cupples LA, Mathias RA, Yanek LR, Becker LC, Peyser PA, Bielak LF, Smith JA, Aslibekyan S, Hidalgo BA, Arnett DK, Irvin MR, Wilson JG, Musani SK, Correa A, Rich SS, Guo X, Rotter JI, Konkle BA, Johnsen JM, Ashley-Koch AE, Telen MJ, Sheehan VA, Blangero J, Curran JE, Peralta JM, Montgomery C, Sheu WH, Chung RH, Schwander K, Nouraie SM, Gordeuk VR, Zhang Y, Kooperberg C, Reiner AP, Jackson RD, Bleecker ER, Meyers DA, Li X, Das S, Yu K, LeFaive J, Smith A, Blackwell T, Taliun D, Zollner S, Forer L, Schoenherr S, Fuchsberger C, Pandit A, Zawistowski M, Kheterpal S, Brummett CM, Natarajan P, Schlessinger D, Lee S, Kang HM, Cucca F, Holmen OL, Åsvold BO, Boehnke M, Kathiresan S, Abecasis GR, Chen YE, Willer CJ, Hveem K. Loss-of-function genomic variants highlight potential therapeutic targets for cardiovascular disease. Nat Commun. 2020 12 18; 11(1):6417. PMID: 33339817.
    Citations: 2     Fields:    Translation:Humans
  30. Guan W, Ko D, Khurshid S, Trisini Lipsanopoulos AT, Ashburner JM, Harrington LX, Rost NS, Atlas SJ, Singer DE, McManus DD, Anderson CD, Lubitz SA. Automated Electronic Phenotyping of Cardioembolic Stroke. Stroke. 2021 01; 52(1):181-189. PMID: 33297865.
    Citations:    Fields:    Translation:Humans
  31. Khurshid S, Kartoun U, Ashburner JM, Trinquart L, Philippakis A, Khera AV, Ellinor PT, Ng K, Lubitz SA. Performance of Atrial Fibrillation Risk Prediction Models in Over 4 Million Individuals. Circ Arrhythm Electrophysiol. 2021 01; 14(1):e008997. PMID: 33295794.
    Citations: 1     Fields:    Translation:Humans
  32. Marston NA, Patel PN, Kamanu FK, Nordio F, Melloni GM, Roselli C, Gurmu Y, Weng LC, Bonaca MP, Giugliano RP, Scirica BM, O'Donoghue ML, Cannon CP, Anderson CD, Bhatt DL, Gabriel Steg P, Cohen M, Storey RF, Sever P, Keech AC, Raz I, Mosenzon O, Antman EM, Braunwald E, Ellinor PT, Lubitz SA, Sabatine MS, Ruff CT. Clinical Application of a Novel Genetic Risk Score for Ischemic Stroke in Patients With Cardiometabolic Disease. Circulation. 2021 Feb 02; 143(5):470-478. PMID: 33185476.
    Citations: 2     Fields:    
  33. Halford JL, Weng LC, Choi SH, Jurgens SJ, Morrill VN, Khurshid S, Trinquart L, Benjamin EJ, Ellinor PT, Lubitz SA. Associations Between Alcohol Intake and Genetic Predisposition With Atrial Fibrillation Risk in a National Biobank. Circ Genom Precis Med. 2020 12; 13(6):e003111. PMID: 33156697.
    Citations:    Fields:    
  34. Hall AW, Chaffin M, Roselli C, Lin H, Lubitz SA, Bianchi V, Geeven G, Bedi K, Margulies KB, de Laat W, Tucker NR, Ellinor PT. Epigenetic Analyses of Human Left Atrial Tissue Identifies Gene Networks Underlying Atrial Fibrillation. Circ Genom Precis Med. 2020 12; 13(6):e003085. PMID: 33155827.
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