Harvard Catalyst Profiles

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Steven Siegel, M.D.


University of Pennsylvania, Philadelphia, PAPhD12/2014Cell and Molecular Biology
University of Pennsylvania, Philadelphia, PAMD05/2016
Boston Children's Hospital and Boston Medical Center, Boston, MA06/2018Pediatric residency
Boston Children's Hospital, Boston, MA07/2022Pediatric Infectious Diseases fellowship

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Zhang RV, Featherstone RE, Melynchenko O, Gifford R, Weger R, Liang Y, Siegel SJ. High-beta/low-gamma frequency activity reflects top-down predictive coding during a spatial working memory test. Exp Brain Res. 2019 Jul; 237(7):1881-1888. PMID: 31093716.
    Citations: 3     Fields:    Translation:Animals
  2. Ward KR, Featherstone RE, Naschek MJ, Melnychenko O, Banerjee A, Yi J, Gifford RL, Borgmann-Winter KE, Salter MW, Hahn CG, Siegel SJ. Src deficient mice demonstrate behavioral and electrophysiological alterations relevant to psychiatric and developmental disease. Prog Neuropsychopharmacol Biol Psychiatry. 2019 07 13; 93:84-92. PMID: 30826459.
    Citations: 5     Fields:    Translation:Animals
  3. Forrest AD, Bang J, Featherstone RE, Bloom JH, Luminais MS, Zhang RV, Gajewski CR, McMullen MF, Liang Y, Siegel SJ. Pyramidal cell-selective GluN1 knockout causes impairments in salience attribution and related EEG activity. Exp Brain Res. 2018 03; 236(3):837-846. PMID: 29350251.
    Citations: 1     Fields:    Translation:AnimalsCells
  4. Port RG, Gajewski C, Krizman E, Dow HC, Hirano S, Brodkin ES, Carlson GC, Robinson MB, Roberts TPL, Siegel SJ. Protocadherin 10 alters ? oscillations, amino acid levels, and their coupling; baclofen partially restores these oscillatory deficits. Neurobiol Dis. 2017 Dec; 108:324-338. PMID: 28844789.
    Citations: 10     Fields:    Translation:Animals
  5. Mihara T, Mensah-Brown K, Sobota R, Lin R, Featherstone R, Siegel SJ. Amygdala activity associated with social choice in mice. Behav Brain Res. 2017 08 14; 332:84-89. PMID: 28438555.
    Citations: 5     Fields:    Translation:Animals
  6. Harrison JD, Dochney JA, Blazekovic S, Leone F, Metzger D, Frank I, Gross R, Hole A, Mounzer K, Siegel S, Schnoll RA, Ashare RL. The nature and consequences of cognitive deficits among tobacco smokers with HIV: a comparison to tobacco smokers without HIV. J Neurovirol. 2017 08; 23(4):550-557. PMID: 28429289; PMCID: PMC5623102.
    Citations: 13     Fields:    Translation:HumansCells
  7. White RS, Bhattacharya AK, Chen Y, Byrd M, McMullen MF, Siegel SJ, Carlson GC, Kim SF. Lysosomal iron modulates NMDA receptor-mediated excitation via small GTPase, Dexras1. Mol Brain. 2016 Apr 14; 9:38. PMID: 27080392; PMCID: PMC4832449.
    Citations: 20     Fields:    Translation:AnimalsCells
  8. Siegel SJ, Tamashiro E, Weiser JN. Clearance of Pneumococcal Colonization in Infants Is Delayed through Altered Macrophage Trafficking. PLoS Pathog. 2015 Jun; 11(6):e1005004. PMID: 26107875; PMCID: PMC4479461.
    Citations: 21     Fields:    Translation:AnimalsCells
  9. Siegel SJ, Weiser JN. Mechanisms of Bacterial Colonization of the Respiratory Tract. Annu Rev Microbiol. 2015; 69:425-44. PMID: 26488280; PMCID: PMC4760621.
    Citations: 80     Fields:    Translation:HumansAnimalsCells
  10. Port RG, Gandal MJ, Roberts TP, Siegel SJ, Carlson GC. Convergence of circuit dysfunction in ASD: a common bridge between diverse genetic and environmental risk factors and common clinical electrophysiology. Front Cell Neurosci. 2014; 8:414. PMID: 25538564; PMCID: PMC4259121.
    Citations: 16     
  11. Featherstone RE, Shin R, Kogan JH, Liang Y, Matsumoto M, Siegel SJ. Mice with subtle reduction of NMDA NR1 receptor subunit expression have a selective decrease in mismatch negativity: Implications for schizophrenia prodromal population. Neurobiol Dis. 2015 Jan; 73:289-95. PMID: 25461194.
    Citations: 21     Fields:    Translation:Animals
  12. Richard AL, Siegel SJ, Erikson J, Weiser JN. TLR2 signaling decreases transmission of Streptococcus pneumoniae by limiting bacterial shedding in an infant mouse Influenza A co-infection model. PLoS Pathog. 2014 Aug; 10(8):e1004339. PMID: 25166617; PMCID: PMC4148449.
    Citations: 35     Fields:    Translation:AnimalsCells
  13. Siegel SJ, Roche AM, Weiser JN. Influenza promotes pneumococcal growth during coinfection by providing host sialylated substrates as a nutrient source. Cell Host Microbe. 2014 Jul 09; 16(1):55-67. PMID: 25011108; PMCID: PMC4096718.
    Citations: 126     Fields:    Translation:AnimalsCells
  14. Forrest AD, Coto CA, Siegel SJ. Animal Models of Psychosis: Current State and Future Directions. Curr Behav Neurosci Rep. 2014 Jun 01; 1(2):100-116. PMID: 25215267; PMCID: PMC4157659.
    Citations: 18     
  15. Billingslea EN, Tatard-Leitman VM, Anguiano J, Jutzeler CR, Suh J, Saunders JA, Morita S, Featherstone RE, Ortinski PI, Gandal MJ, Lin R, Liang Y, Gur RE, Carlson GC, Hahn CG, Siegel SJ. Parvalbumin cell ablation of NMDA-R1 causes increased resting network excitability with associated social and self-care deficits. Neuropsychopharmacology. 2014 Jun; 39(7):1603-13. PMID: 24525709; PMCID: PMC4023157.
    Citations: 52     Fields:    Translation:AnimalsCells
  16. Siegel SJ. Capacity, confidentiality and consequences: balancing responsible medical care with mental health law. Curr Psychiatry Rep. 2013 Aug; 15(8):380. PMID: 23881711; PMCID: PMC3786359.
    Citations: 1     Fields:    Translation:Humans
  17. Schoenfeld BP, Choi RJ, Choi CH, Terlizzi AM, Hinchey P, Kollaros M, Ferrick NJ, Koenigsberg E, Ferreiro D, Leibelt DA, Siegel SJ, Bell AJ, McDonald TV, Jongens TA, McBride SM. The Drosophila DmGluRA is required for social interaction and memory. Front Pharmacol. 2013; 4:64. PMID: 23720628.
    Citations: 7     
  18. Saunders JA, Tatard-Leitman VM, Suh J, Billingslea EN, Roberts TP, Siegel SJ. Knockout of NMDA receptors in parvalbumin interneurons recreates autism-like phenotypes. Autism Res. 2013 Apr; 6(2):69-77. PMID: 23441094; PMCID: PMC4064157.
    Citations: 53     Fields:    Translation:AnimalsCells
  19. Featherstone RE, M Tatard-Leitman V, Suh JD, Lin R, Lucki I, Siegel SJ. Electrophysiological and behavioral responses to ketamine in mice with reduced Akt1 expression. Psychopharmacology (Berl). 2013 Jun; 227(4):639-49. PMID: 23392353; PMCID: PMC3808977.
    Citations: 8     Fields:    Translation:Animals
  20. Uchil PD, Hinz A, Siegel S, Coenen-Stass A, Pertel T, Luban J, Mothes W. TRIM protein-mediated regulation of inflammatory and innate immune signaling and its association with antiretroviral activity. J Virol. 2013 Jan; 87(1):257-72. PMID: 23077300.
    Citations: 102     Fields:    Translation:HumansCells
  21. Featherstone RE, Phillips JM, Thieu T, Ehrlichman RS, Halene TB, Leiser SC, Christian E, Johnson E, Lerman C, Siegel SJ. Nicotine receptor subtype-specific effects on auditory evoked oscillations and potentials. PLoS One. 2012; 7(7):e39775. PMID: 22911690; PMCID: PMC3401200.
    Citations: 7     Fields:    Translation:HumansAnimalsCells
  22. Featherstone RE, Liang Y, Saunders JA, Tatard-Leitman VM, Ehrlichman RS, Siegel SJ. Subchronic ketamine treatment leads to permanent changes in EEG, cognition and the astrocytic glutamate transporter EAAT2 in mice. Neurobiol Dis. 2012 Sep; 47(3):338-46. PMID: 22627142.
    Citations: 36     Fields:    Translation:AnimalsCells
  23. Liao W, Gandal MJ, Ehrlichman RS, Siegel SJ, Carlson GC. MeCP2+/- mouse model of RTT reproduces auditory phenotypes associated with Rett syndrome and replicate select EEG endophenotypes of autism spectrum disorder. Neurobiol Dis. 2012 Apr; 46(1):88-92. PMID: 22249109; PMCID: PMC3299908.
    Citations: 31     Fields:    Translation:HumansAnimals
  24. Mehta MV, Gandal MJ, Siegel SJ. mGluR5-antagonist mediated reversal of elevated stereotyped, repetitive behaviors in the VPA model of autism. PLoS One. 2011; 6(10):e26077. PMID: 22016815; PMCID: PMC3189241.
    Citations: 68     Fields:    Translation:Animals
  25. Carlson GC, Talbot K, Halene TB, Gandal MJ, Kazi HA, Schlosser L, Phung QH, Gur RE, Arnold SE, Siegel SJ. Dysbindin-1 mutant mice implicate reduced fast-phasic inhibition as a final common disease mechanism in schizophrenia. Proc Natl Acad Sci U S A. 2011 Oct 25; 108(43):E962-70. PMID: 21969553.
    Citations: 61     Fields:    Translation:AnimalsCells
  26. Makadia HK, Siegel SJ. Poly Lactic-co-Glycolic Acid (PLGA) as Biodegradable Controlled Drug Delivery Carrier. Polymers (Basel). 2011 Sep 01; 3(3):1377-1397. PMID: 22577513; PMCID: PMC3347861.
    Citations: 942     
  27. Siegel SJ. What can we expect from long-acting formulations for schizophrenia? Curr Psychiatry Rep. 2011 Aug; 13(4):243-4. PMID: 21584690.
    Citations:    Fields:    
  28. Loughead J, Ray R, Wileyto EP, Ruparel K, O'Donnell GP, Senecal N, Siegel S, Gur RC, Lerman C. Brain activity and emotional processing in smokers treated with varenicline. Addict Biol. 2013 Jul; 18(4):732-8. PMID: 21507156.
    Citations: 12     Fields:    Translation:HumansCTClinical Trials
  29. Gandal MJ, Edgar JC, Klook K, Siegel SJ. Gamma synchrony: towards a translational biomarker for the treatment-resistant symptoms of schizophrenia. Neuropharmacology. 2012 Mar; 62(3):1504-18. PMID: 21349276; PMCID: PMC3264822.
    Citations: 127     Fields:    Translation:HumansAnimals
  30. Gandal MJ, Edgar JC, Ehrlichman RS, Mehta M, Roberts TP, Siegel SJ. Validating ? oscillations and delayed auditory responses as translational biomarkers of autism. Biol Psychiatry. 2010 Dec 15; 68(12):1100-6. PMID: 21130222; PMCID: PMC5070466.
    Citations: 142     Fields:    Translation:HumansAnimals
  31. Siegel SJ. Resurgence of long-acting antipsychotic formulations. Curr Psychiatry Rep. 2010 Aug; 12(4):276-8. PMID: 20424976.
    Citations:    Fields:    
  32. Lazarewicz MT, Ehrlichman RS, Maxwell CR, Gandal MJ, Finkel LH, Siegel SJ. Ketamine modulates theta and gamma oscillations. J Cogn Neurosci. 2010 Jul; 22(7):1452-64. PMID: 19583475.
    Citations: 105     Fields:    Translation:Animals
  33. Wang CK, Wang WY, Meyer RF, Liang Y, Winey KI, Siegel SJ. A rapid method for creating drug implants: translating laboratory-based methods into a scalable manufacturing process. J Biomed Mater Res B Appl Biomater. 2010 May; 93(2):562-72. PMID: 20225251; PMCID: PMC3049914.
    Citations: 4     Fields:    Translation:Animals
  34. Amann LC, Gandal MJ, Halene TB, Ehrlichman RS, White SL, McCarren HS, Siegel SJ. Mouse behavioral endophenotypes for schizophrenia. Brain Res Bull. 2010 Sep 30; 83(3-4):147-61. PMID: 20433908.
    Citations: 67     Fields:    Translation:HumansAnimals
  35. Amann LC, Gandal MJ, Lin R, Liang Y, Siegel SJ. In vitro-in vivo correlations of scalable PLGA-risperidone implants for the treatment of schizophrenia. Pharm Res. 2010 Aug; 27(8):1730-7. PMID: 20422263.
    Citations: 24     Fields:    Translation:HumansAnimals
  36. Rudnick ND, Strasser AA, Phillips JM, Jepson C, Patterson F, Frey JM, Turetsky BI, Lerman C, Siegel SJ. Mouse model predicts effects of smoking and varenicline on event-related potentials in humans. Nicotine Tob Res. 2010 Jun; 12(6):589-97. PMID: 20395358.
    Citations: 8     Fields:    Translation:HumansAnimals
  37. Li X, Du Y, Siegel S, Ferro-Novick S, Novick P. Activation of the mitogen-activated protein kinase, Slt2p, at bud tips blocks a late stage of endoplasmic reticulum inheritance in Saccharomyces cerevisiae. Mol Biol Cell. 2010 May 15; 21(10):1772-82. PMID: 20357006; PMCID: PMC2869382.
    Citations: 10     Fields:    Translation:AnimalsCells
  38. Satterthwaite TD, Wolf DH, Loughead J, Ruparel K, Valdez JN, Siegel SJ, Kohler CG, Gur RE, Gur RC. Association of enhanced limbic response to threat with decreased cortical facial recognition memory response in schizophrenia. Am J Psychiatry. 2010 Apr; 167(4):418-26. PMID: 20194482; PMCID: PMC4243460.
    Citations: 29     Fields:    Translation:Humans
  39. Rabin CR, Siegel SJ. Antipsychotic dosing and drug delivery. Curr Top Behav Neurosci. 2010; 4:141-77. PMID: 21312400.
    Citations: 1     Fields:    Translation:HumansAnimals
  40. Halene TB, Talmud J, Jonak GJ, Schneider F, Siegel SJ. Predator odor modulates auditory event-related potentials in mice. Neuroreport. 2009 Sep 23; 20(14):1260-4. PMID: 19625986.
    Citations: 4     Fields:    Translation:Animals
  41. Siegel SJ, Percopo CM, Dyer KD, Zhao W, Roth VL, Mercer JM, Rosenberg HF. RNase 1 genes from the family Sciuridae define a novel rodent ribonuclease cluster. Mamm Genome. 2009 Nov-Dec; 20(11-12):749-57. PMID: 19771477; PMCID: PMC2809794.
    Citations: 2     Fields:    Translation:AnimalsCells
  42. Patterson F, Jepson C, Loughead J, Perkins K, Strasser AA, Siegel S, Frey J, Gur R, Lerman C. Working memory deficits predict short-term smoking resumption following brief abstinence. Drug Alcohol Depend. 2010 Jan 01; 106(1):61-4. PMID: 19733449; PMCID: PMC2815089.
    Citations: 111     Fields:    Translation:Humans
  43. Ehrlichman RS, Luminais SN, White SL, Rudnick ND, Ma N, Dow HC, Kreibich AS, Abel T, Brodkin ES, Hahn CG, Siegel SJ. Neuregulin 1 transgenic mice display reduced mismatch negativity, contextual fear conditioning and social interactions. Brain Res. 2009 Oct 19; 1294:116-27. PMID: 19643092.
    Citations: 54     Fields:    Translation:Animals
  44. Amann LC, Halene TB, Ehrlichman RS, Luminais SN, Ma N, Abel T, Siegel SJ. Chronic ketamine impairs fear conditioning and produces long-lasting reductions in auditory evoked potentials. Neurobiol Dis. 2009 Aug; 35(2):311-7. PMID: 19467327; PMCID: PMC2726963.
    Citations: 18     Fields:    Translation:Animals
  45. Turetsky BI, Bilker WB, Siegel SJ, Kohler CG, Gur RE. Profile of auditory information-processing deficits in schizophrenia. Psychiatry Res. 2009 Jan 30; 165(1-2):27-37. PMID: 18990453; PMCID: PMC2652872.
    Citations: 49     Fields:    Translation:Humans
  46. Rudnick ND, Koehler C, Picciotto MR, Siegel SJ. Role of beta2-containing nicotinic acetylcholine receptors in auditory event-related potentials. Psychopharmacology (Berl). 2009 Mar; 202(4):745-51. PMID: 18931833.
    Citations: 12     Fields:    Translation:Animals
  47. Dyer KD, Moser JM, Czapiga M, Siegel SJ, Percopo CM, Rosenberg HF. Functionally competent eosinophils differentiated ex vivo in high purity from normal mouse bone marrow. J Immunol. 2008 Sep 15; 181(6):4004-9. PMID: 18768855; PMCID: PMC2680436.
    Citations: 149     Fields:    Translation:AnimalsCells
  48. Ehrlichman RS, Maxwell CR, Majumdar S, Siegel SJ. Deviance-elicited changes in event-related potentials are attenuated by ketamine in mice. J Cogn Neurosci. 2008 Aug; 20(8):1403-14. PMID: 18303985.
    Citations: 69     Fields:    Translation:Animals
  49. Dankert ME, Brensinger CM, Metzger KL, Li C, Koleva SG, Mesén A, Laprade B, Wiguna T, Han C, Farooq S, Severus WE, Gayares JG, Langosch JM, Lallart X, Tateno M, Mihai A, Nair SR, Belmaker R, Rybakowski J, Owe-Larsson B, Kane JM, Johnstone EC, MacIntyre DJ, Malhotra S, González-Pinto A, Mosquera F, Babb SM, Habib pour E, Fatemi SS, Swanson C, Adler C, Young A, Hoeft F, Sivakumar K, Radoeva PD, Lallart EA, Bilker WB, Siegel SJ. Attitudes of patients and family members towards implantable psychiatric medication. Schizophr Res. 2008 Oct; 105(1-3):279-86. PMID: 18571376.
    Citations: 1     Fields:    Translation:Humans
  50. Kelly MP, Cheung YF, Favilla C, Siegel SJ, Kanes SJ, Houslay MD, Abel T. Constitutive activation of the G-protein subunit Galphas within forebrain neurons causes PKA-dependent alterations in fear conditioning and cortical Arc mRNA expression. Learn Mem. 2008 Feb; 15(2):75-83. PMID: 18230676; PMCID: PMC2216679.
    Citations: 22     Fields:    Translation:AnimalsCells
  51. Hans ML, Maxwell C, Ehrlichman RS, Metzger K, Liang Y, Siegel SJ, Lowman AM. Evaluation of in vitro release and in vivo efficacy of mPEG-PLA-haloperidol conjugate micelle-like structures. J Biomed Mater Res B Appl Biomater. 2007 Nov; 83(2):422-30. PMID: 17415770.
    Citations: 3     Fields:    Translation:Animals
  52. Majewski-Tiedeken CR, Rabin CR, Siegel SJ. Ketamine exposure in adult mice leads to increased cell death in C3H, DBA2 and FVB inbred mouse strains. Drug Alcohol Depend. 2008 Jan 01; 92(1-3):217-27. PMID: 17920787; PMCID: PMC2234578.
    Citations: 15     Fields:    Translation:AnimalsCells
  53. Halene TB, Siegel SJ. PDE inhibitors in psychiatry--future options for dementia, depression and schizophrenia? Drug Discov Today. 2007 Oct; 12(19-20):870-8. PMID: 17933689.
    Citations: 23     Fields:    Translation:HumansAnimals
  54. Lerman C, LeSage MG, Perkins KA, O'Malley SS, Siegel SJ, Benowitz NL, Corrigall WA. Translational research in medication development for nicotine dependence. Nat Rev Drug Discov. 2007 Sep; 6(9):746-62. PMID: 17690709.
    Citations: 86     Fields:    Translation:HumansAnimals
  55. Dyer KD, Czapiga M, Foster B, Foster PS, Kang EM, Lappas CM, Moser JM, Naumann N, Percopo CM, Siegel SJ, Swartz JM, Ting-De Ravin S, Rosenberg HF. Eosinophils from lineage-ablated Delta dblGATA bone marrow progenitors: the dblGATA enhancer in the promoter of GATA-1 is not essential for differentiation ex vivo. J Immunol. 2007 Aug 01; 179(3):1693-9. PMID: 17641035.
    Citations: 16     Fields:    Translation:AnimalsCells
  56. Siegel SJ, O'Neill C, Dubé LM, Kaldeway P, Morris R, Jackson D, Sebree T. A unique iontophoretic patch for optimal transdermal delivery of sumatriptan. Pharm Res. 2007 Oct; 24(10):1919-26. PMID: 17577644.
    Citations: 11     Fields:    Translation:HumansCTClinical Trials
  57. Budhian A, Siegel SJ, Winey KI. Controlling the in vitro release profiles for a system of haloperidol-loaded PLGA nanoparticles. Int J Pharm. 2008 Jan 04; 346(1-2):151-9. PMID: 17681683.
    Citations: 38     Fields:    
  58. Gur RE, Turetsky BI, Loughead J, Snyder W, Kohler C, Elliott M, Pratiwadi R, Ragland JD, Bilker WB, Siegel SJ, Kanes SJ, Arnold SE, Gur RC. Visual attention circuitry in schizophrenia investigated with oddball event-related functional magnetic resonance imaging. Am J Psychiatry. 2007 Mar; 164(3):442-9. PMID: 17329469.
    Citations: 37     Fields:    Translation:Humans
  59. Budhian A, Siegel SJ, Winey KI. Haloperidol-loaded PLGA nanoparticles: systematic study of particle size and drug content. Int J Pharm. 2007 May 24; 336(2):367-75. PMID: 17207944.
    Citations: 82     Fields:    Translation:Cells
  60. Metzger KL, Shoemaker JM, Kahn JB, Maxwell CR, Liang Y, Tokarczyk J, Kanes SJ, Hans M, Lowman AM, Dan N, Winey KI, Swerdlow NR, Siegel SJ. Pharmacokinetic and behavioral characterization of a long-term antipsychotic delivery system in rodents and rabbits. Psychopharmacology (Berl). 2007 Feb; 190(2):201-11. PMID: 17119931.
    Citations: 4     Fields:    Translation:Animals
  61. Moberg PJ, Arnold SE, Doty RL, Gur RE, Balderston CC, Roalf DR, Gur RC, Kohler CG, Kanes SJ, Siegel SJ, Turetsky BI. Olfactory functioning in schizophrenia: relationship to clinical, neuropsychological, and volumetric MRI measures. J Clin Exp Neuropsychol. 2006 Nov; 28(8):1444-61. PMID: 17050269.
    Citations: 41     Fields:    Translation:Humans
  62. Irani F, Platek SM, Panyavin IS, Calkins ME, Kohler C, Siegel SJ, Schachter M, Gur RE, Gur RC. Self-face recognition and theory of mind in patients with schizophrenia and first-degree relatives. Schizophr Res. 2006 Dec; 88(1-3):151-60. PMID: 16979876.
    Citations: 38     Fields:    Translation:HumansPHPublic Health
  63. Hahn CG, Wang HY, Cho DS, Talbot K, Gur RE, Berrettini WH, Bakshi K, Kamins J, Borgmann-Winter KE, Siegel SJ, Gallop RJ, Arnold SE. Altered neuregulin 1-erbB4 signaling contributes to NMDA receptor hypofunction in schizophrenia. Nat Med. 2006 Jul; 12(7):824-8. PMID: 16767099.
    Citations: 258     Fields:    Translation:HumansAnimalsCells
  64. Kelly MP, Isiegas C, Cheung YF, Tokarczyk J, Yang X, Esposito MF, Rapoport DA, Fabian SA, Siegel SJ, Wand G, Houslay MD, Kanes SJ, Abel T. Constitutive activation of Galphas within forebrain neurons causes deficits in sensorimotor gating because of PKA-dependent decreases in cAMP. Neuropsychopharmacology. 2007 Mar; 32(3):577-88. PMID: 16738544; PMCID: PMC3303872.
    Citations: 36     Fields:    Translation:AnimalsCells
  65. Maxwell CR, Ehrlichman RS, Liang Y, Gettes DR, Evans DL, Kanes SJ, Abel T, Karp J, Siegel SJ. Corticosterone modulates auditory gating in mouse. Neuropsychopharmacology. 2006 May; 31(5):897-903. PMID: 16123740.
    Citations: 9     Fields:    Translation:Animals
  66. Siegel SJ, Irani F, Brensinger CM, Kohler CG, Bilker WB, Ragland JD, Kanes SJ, Gur RC, Gur RE. Prognostic variables at intake and long-term level of function in schizophrenia. Am J Psychiatry. 2006 Mar; 163(3):433-41. PMID: 16513864.
    Citations: 28     Fields:    Translation:Humans
  67. Metzger KL, Maxwell CR, Liang Y, Siegel SJ. Effects of nicotine vary across two auditory evoked potentials in the mouse. Biol Psychiatry. 2007 Jan 01; 61(1):23-30. PMID: 16497274.
    Citations: 29     Fields:    Translation:Animals
  68. Roalf DR, Turetsky BI, Owzar K, Balderston CC, Johnson SC, Brensinger CM, Gur RE, Siegel SJ, Moberg PJ. Unirhinal olfactory function in schizophrenia patients and first-degree relatives. J Neuropsychiatry Clin Neurosci. 2006; 18(3):389-96. PMID: 16963589.
    Citations: 12     Fields:    Translation:Humans
  69. Budhian A, Siegel SJ, Winey KI. Production of haloperidol-loaded PLGA nanoparticles for extended controlled drug release of haloperidol. J Microencapsul. 2005 Nov; 22(7):773-85. PMID: 16421087.
    Citations: 18     Fields:    
  70. Ragland JD, Gur RC, Valdez JN, Loughead J, Elliott M, Kohler C, Kanes S, Siegel SJ, Moelter ST, Gur RE. Levels-of-processing effect on frontotemporal function in schizophrenia during word encoding and recognition. Am J Psychiatry. 2005 Oct; 162(10):1840-8. PMID: 16199830; PMCID: PMC4332803.
    Citations: 46     Fields:    Translation:Humans
  71. Maxwell CR, Ehrlichman RS, Liang Y, Trief D, Kanes SJ, Karp J, Siegel SJ. Ketamine produces lasting disruptions in encoding of sensory stimuli. J Pharmacol Exp Ther. 2006 Jan; 316(1):315-24. PMID: 16192313.
    Citations: 63     Fields:    Translation:Animals
  72. Hans M, Shimoni K, Danino D, Siegel SJ, Lowman A. Synthesis and characterization of mPEG-PLA prodrug micelles. Biomacromolecules. 2005 Sep-Oct; 6(5):2708-17. PMID: 16153110.
    Citations: 7     Fields:    
  73. Irani F, Dankert M, Siegel SJ. Patient and family attitudes toward schizophrenia treatment. Curr Psychiatry Rep. 2004 Aug; 6(4):283-8. PMID: 15260944.
    Citations: 2     Fields:    Translation:Humans
  74. Connolly PM, Maxwell C, Liang Y, Kahn JB, Kanes SJ, Abel T, Gur RE, Turetsky BI, Siegel SJ. The effects of ketamine vary among inbred mouse strains and mimic schizophrenia for the P80, but not P20 or N40 auditory ERP components. Neurochem Res. 2004 Jun; 29(6):1179-88. PMID: 15176475.
    Citations: 41     Fields:    Translation:HumansAnimals
  75. Irani F, Dankert M, Brensinger C, Bilker WB, Nair SR, Kohler CG, Kanes SJ, Turetsky BI, Moberg PJ, Ragland JD, Gur RC, Gur RE, Siegel SJ. Patient attitudes towards surgically implantable, long-term delivery of psychiatric medicine. Neuropsychopharmacology. 2004 May; 29(5):960-8. PMID: 14970826.
    Citations: 5     Fields:    Translation:Humans
  76. Maxwell CR, Liang Y, Weightman BD, Kanes SJ, Abel T, Gur RE, Turetsky BI, Bilker WB, Lenox RH, Siegel SJ. Effects of chronic olanzapine and haloperidol differ on the mouse N1 auditory evoked potential. Neuropsychopharmacology. 2004 Apr; 29(4):739-46. PMID: 14735128.
    Citations: 26     Fields:    Translation:Animals
  77. Gelber EI, Kohler CG, Bilker WB, Gur RC, Brensinger C, Siegel SJ, Gur RE. Symptom and demographic profiles in first-episode schizophrenia. Schizophr Res. 2004 Apr 01; 67(2-3):185-94. PMID: 14984877.
    Citations: 11     Fields:    Translation:Humans
  78. Gur RE, Kohler C, Turetsky BI, Siegel SJ, Kanes SJ, Bilker WB, Brennan AR, Gur RC. A sexually dimorphic ratio of orbitofrontal to amygdala volume is altered in schizophrenia. Biol Psychiatry. 2004 Mar 01; 55(5):512-7. PMID: 15023579.
    Citations: 41     Fields:    Translation:HumansCTClinical Trials
  79. Ragland JD, Moelter ST, McGrath C, Hill SK, Gur RE, Bilker WB, Siegel SJ, Gur RC. Levels-of-processing effect on word recognition in schizophrenia. Biol Psychiatry. 2003 Dec 01; 54(11):1154-61. PMID: 14643082; PMCID: PMC4332587.
    Citations: 32     Fields:    Translation:Humans
  80. Connolly PM, Maxwell CR, Kanes SJ, Abel T, Liang Y, Tokarczyk J, Bilker WB, Turetsky BI, Gur RE, Siegel SJ. Inhibition of auditory evoked potentials and prepulse inhibition of startle in DBA/2J and DBA/2Hsd inbred mouse substrains. Brain Res. 2003 Nov 28; 992(1):85-95. PMID: 14604776.
    Citations: 28     Fields:    Translation:Animals
  81. Gur RE, Kohler C, Ragland JD, Siegel SJ, Bilker WB, Loughead J, Phend N, Gur RC. Neurocognitive performance and clinical changes in olanzapine-treated patients with schizophrenia. Neuropsychopharmacology. 2003 Nov; 28(11):2029-36. PMID: 12902996.
    Citations: 5     Fields:    Translation:Humans
  82. Kohler CG, Turner TH, Bilker WB, Brensinger CM, Siegel SJ, Kanes SJ, Gur RE, Gur RC. Facial emotion recognition in schizophrenia: intensity effects and error pattern. Am J Psychiatry. 2003 Oct; 160(10):1768-74. PMID: 14514489.
    Citations: 226     Fields:    Translation:Humans
  83. Siegel SJ, Connolly P, Liang Y, Lenox RH, Gur RE, Bilker WB, Kanes SJ, Turetsky BI. Effects of strain, novelty, and NMDA blockade on auditory-evoked potentials in mice. Neuropsychopharmacology. 2003 Apr; 28(4):675-82. PMID: 12655312.
    Citations: 46     Fields:    Translation:Animals
  84. Siegel SJ, Winey KI, Gur RE, Lenox RH, Bilker WB, Ikeda D, Gandhi N, Zhang WX. Surgically implantable long-term antipsychotic delivery systems for the treatment of schizophrenia. Neuropsychopharmacology. 2002 Jun; 26(6):817-23. PMID: 12007752.
    Citations: 11     Fields:    Translation:Animals
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.