Harvard Catalyst Profiles

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Nadia Alatrakchi, Ph.D., M.D.

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Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Altinbas A, Holmes JA, Salloum S, Lidofsky A, Alatrakchi N, Somsouk M, Hunt P, Deeks S, Chew KW, Lauer G, Kruger A, Lin W, Chung RT. LOXL-2 and TNC-C are markers of liver fibrogenesis in HCV/HIV-, HIV- and HCV-infected patients. Biomark Med. 2022 08; 16(11):839-846. PMID: 35786977; PMCID: PMC9437769.
    Citations: 1     Fields:    Translation:Humans
  2. Tonnerre P, Wolski D, Subudhi S, Aljabban J, Hoogeveen RC, Damasio M, Drescher HK, Bartsch LM, Tully DC, Sen DR, Bean DJ, Brown J, Torres-Cornejo A, Robidoux M, Kvistad D, Alatrakchi N, Cui A, Lieb D, Cheney JA, Gustafson J, Lewis-Ximenez LL, Massenet-Regad L, Eisenhaure T, Aneja J, Haining WN, Chung RT, Hacohen N, Allen TM, Kim AY, Lauer GM. Differentiation of exhausted CD8+ T cells after termination of chronic antigen stimulation stops short of achieving functional T cell memory. Nat Immunol. 2021 08; 22(8):1030-1041. PMID: 34312544; PMCID: PMC8323980.
    Citations: 18     Fields:    Translation:HumansCells
  3. Salloum S, Jeyarajan AJ, Kruger AJ, Holmes JA, Shao T, Sojoodi M, Kim MH, Zhuo Z, Shroff SG, Kassa A, Corey KE, Khan SK, Lin W, Alatrakchi N, Schaefer EAK, Chung RT. Fatty Acids Activate the Transcriptional Coactivator YAP1 to Promote Liver Fibrosis via p38 Mitogen-Activated Protein Kinase. Cell Mol Gastroenterol Hepatol. 2021; 12(4):1297-1310. PMID: 34118488; PMCID: PMC8463869.
    Citations: 9     Fields:    Translation:HumansAnimalsCells
  4. Holmes JA, Carlton-Smith C, Kim AY, Dumas EO, Brown J, Gustafson JL, Lauer GM, Silva ST, Robidoux M, Kvistad D, Alatrakchi N, Tonnerre P, Cohen DE, Zhang H, Shulman NS, Chung RT. Dynamic changes in innate immune responses during direct-acting antiviral therapy for HCV infection. J Viral Hepat. 2019 03; 26(3):362-372. PMID: 30450781.
    Citations: 11     Fields:    Translation:HumansCellsCTClinical Trials
  5. Lidofsky A, Holmes JA, Feeney ER, Kruger AJ, Salloum S, Zheng H, Seguin IS, Altinbas A, Masia R, Corey KE, Gustafson JL, Schaefer EA, Hunt PW, Deeks S, Somsouk M, Chew KW, Chung RT, Alatrakchi N. Macrophage Activation Marker Soluble CD163 Is a Dynamic Marker of Liver Fibrogenesis in Human Immunodeficiency Virus/Hepatitis C Virus Coinfection. J Infect Dis. 2018 09 22; 218(9):1394-1403. PMID: 29868909; PMCID: PMC6151081.
    Citations: 24     Fields:    Translation:HumansCells
  6. Kruger AJ, Fuchs BC, Masia R, Holmes JA, Salloum S, Sojoodi M, Ferreira DS, Rutledge SM, Caravan P, Alatrakchi N, Vig P, Lefebvre E, Chung RT. Prolonged cenicriviroc therapy reduces hepatic fibrosis despite steatohepatitis in a diet-induced mouse model of nonalcoholic steatohepatitis. Hepatol Commun. 2018 May; 2(5):529-545. PMID: 29761169; PMCID: PMC5944590.
    Citations: 25     Fields:    
  7. Exley MA, Friedlander P, Alatrakchi N, Vriend L, Yue S, Sasada T, Zeng W, Mizukami Y, Clark J, Nemer D, LeClair K, Canning C, Daley H, Dranoff G, Giobbie-Hurder A, Hodi FS, Ritz J, Balk SP. Adoptive Transfer of Invariant NKT Cells as Immunotherapy for Advanced Melanoma: A Phase I Clinical Trial. Clin Cancer Res. 2017 Jul 15; 23(14):3510-3519. PMID: 28193627; PMCID: PMC5511564.
    Citations: 68     Fields:    Translation:HumansCellsCTClinical Trials
  8. Salloum S, Holmes JA, Jindal R, Bale SS, Brisac C, Alatrakchi N, Lidofsky A, Kruger AJ, Fusco DN, Luther J, Schaefer EA, Lin W, Yarmush ML, Chung RT. Exposure to human immunodeficiency virus/hepatitis C virus in hepatic and stellate cell lines reveals cooperative profibrotic transcriptional activation between viruses and cell types. Hepatology. 2016 12; 64(6):1951-1968. PMID: 27531241.
    Citations: 24     Fields:    Translation:HumansCells
  9. Brisac C, Salloum S, Yang V, Schaefer EA, Holmes JA, Chevaliez S, Hong J, Carlton-Smith C, Alatrakchi N, Kruger A, Lin W, Chung RT. IQGAP2 is a novel interferon-alpha antiviral effector gene acting non-conventionally through the NF-?B pathway. J Hepatol. 2016 11; 65(5):972-979. PMID: 27401546; PMCID: PMC5656012.
    Citations: 9     Fields:    Translation:HumansCells
  10. Mueller JL, Feeney ER, Zheng H, Misdraji J, Kruger AJ, Alatrakchi N, King LY, Gelrud L, Corey KE, Chung RT. Circulating Soluble CD163 is Associated with Steatohepatitis and Advanced Fibrosis in Nonalcoholic Fatty Liver Disease. Clin Transl Gastroenterol. 2015 Oct 08; 6:e114. PMID: 26448455.
    Citations: 19     Fields:    
  11. Alatrakchi N. Bregs in Chronic HBV: Is It Time for Bragging Rights? Dig Dis Sci. 2015 May; 60(5):1115-7. PMID: 25686744.
    Citations: 3     Fields:    Translation:HumansCells
  12. Yanagisawa K, Yue S, van der Vliet HJ, Wang R, Alatrakchi N, Golden-Mason L, Schuppan D, Koziel MJ, Rosen HR, Exley MA. Ex vivo analysis of resident hepatic pro-inflammatory CD1d-reactive T cells and hepatocyte surface CD1d expression in hepatitis C. J Viral Hepat. 2013 Aug; 20(8):556-65. PMID: 23808994.
    Citations: 15     Fields:    Translation:HumansAnimalsCells
  13. Li S, Vriend LE, Nasser IA, Popov Y, Afdhal NH, Koziel MJ, Schuppan D, Exley MA, Alatrakchi N. Hepatitis C virus-specific T-cell-derived transforming growth factor beta is associated with slow hepatic fibrogenesis. Hepatology. 2012 Dec; 56(6):2094-105. PMID: 22806830; PMCID: PMC3508175.
    Citations: 7     Fields:    Translation:HumansCells
  14. Exley MA, Lynch L, Varghese B, Nowak M, Alatrakchi N, Balk SP. Developing understanding of the roles of CD1d-restricted T cell subsets in cancer: reversing tumor-induced defects. Clin Immunol. 2011 Aug; 140(2):184-95. PMID: 21646050.
    Citations: 25     Fields:    Translation:HumansCells
  15. Gandhi RT, Zheng L, Bosch RJ, Chan ES, Margolis DM, Read S, Kallungal B, Palmer S, Medvik K, Lederman MM, Alatrakchi N, Jacobson JM, Wiegand A, Kearney M, Coffin JM, Mellors JW, Eron JJ. The effect of raltegravir intensification on low-level residual viremia in HIV-infected patients on antiretroviral therapy: a randomized controlled trial. PLoS Med. 2010 Aug 10; 7(8). PMID: 20711481.
    Citations: 174     Fields:    Translation:HumansCells
  16. Alatrakchi N, Koziel M. Regulatory T cells and viral liver disease. J Viral Hepat. 2009 Apr; 16(4):223-9. PMID: 19222744.
    Citations: 32     Fields:    Translation:HumansCells
  17. Alatrakchi N, Graham CS, van der Vliet HJ, Sherman KE, Exley MA, Koziel MJ. Hepatitis C virus (HCV)-specific CD8+ cells produce transforming growth factor beta that can suppress HCV-specific T-cell responses. J Virol. 2007 Jun; 81(11):5882-92. PMID: 17376924; PMCID: PMC1900307.
    Citations: 45     Fields:    Translation:HumansCells
  18. Alatrakchi N, Damond F, Matheron S, Beretta-Tempelhoff S, Campa P, Carcelain G, Brun-Vezinet F, Autran B. Proliferative, IFNgamma and IL-2-producing T-cell responses to HIV-2 in untreated HIV-2 infection. AIDS. 2006 Jan 02; 20(1):29-34. PMID: 16327316.
    Citations: 9     Fields:    Translation:HumansCells
  19. Alatrakchi N, Graham CS, He Q, Sherman KE, Koziel MJ. CD8+ cell responses to hepatitis C virus (HCV) in the liver of persons with HCV-HIV coinfection versus HCV monoinfection. J Infect Dis. 2005 Mar 01; 191(5):702-9. PMID: 15688283.
    Citations: 15     Fields:    Translation:HumansCells
  20. Alatrakchi N, Duvivier C, Costagliola D, Samri A, Marcelin AG, Kamkamidze G, Astriti M, Agher R, Calvez V, Autran B, Katlama C. Persistent low viral load on antiretroviral therapy is associated with T cell-mediated control of HIV replication. AIDS. 2005 Jan 03; 19(1):25-33. PMID: 15627030.
    Citations: 17     Fields:    Translation:HumansCells
  21. Alatrakchi N, Di Martino V, Thibault V, Benhamou Y, Katlama C, Poynard T, Autran B. Decreased frequencies of virus-specific T helper type 1 cells during interferon alpha plus ribavirin treatment in HIV-hepatitis C virus co-infection. AIDS. 2004 Jan 02; 18(1):121-3. PMID: 15090839.
    Citations: 4     Fields:    Translation:HumansCells
  22. Alatrakchi N, Koziel MJ. A tale of two viruses: hepatitis C in the age of HAART. Lancet. 2003 Nov 22; 362(9397):1687-8. PMID: 14643113.
    Citations: 3     Fields:    Translation:HumansCells
  23. Alatrakchi N, Koziel MJ. Antiviral T-cell responses and therapy in chronic hepatitis B. J Hepatol. 2003 Oct; 39(4):631-4. PMID: 12971976.
    Citations: 7     Fields:    Translation:HumansCells
  24. De La Lande B, Hacene K, Floiras JL, Alatrakchi N, Pichon MF. Prognostic value of CA 15.3 kinetics for metastatic breast cancer. Int J Biol Markers. 2002 Oct-Dec; 17(4):231-8. PMID: 12521126.
    Citations: 5     Fields:    Translation:Humans
  25. Alatrakchi N, Di Martino V, Thibault V, Autran B. Strong CD4 Th1 responses to HIV and hepatitis C virus in HIV-infected long-term non-progressors co-infected with hepatitis C virus. AIDS. 2002 Mar 29; 16(5):713-7. PMID: 11964527.
    Citations: 17     Fields:    Translation:HumansCells
  26. Alatrakchi N, Farace F, Frau E, Carde P, Munck JN, Triebel F. T-cell clonal expansion in patients with B-cell lymphoproliferative disorders. J Immunother. 1998 Sep; 21(5):363-70. PMID: 9789198.
    Citations: 4     Fields:    Translation:HumansCells
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.