Harvard Catalyst Profiles

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Facundo Batista, Ph.D.

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Research
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. R01AI153098 (LINGWOOD, DANIEL) Aug 19, 2020 - Jul 31, 2024
    NIH
    Triggering germline-encoded broadly neutralizing antibody responses against influenza virus
    Role: Co-Principal Investigator
  2. R01AI135052 (BATISTA, FACUNDO DAMIAN) Mar 1, 2018 - Feb 28, 2023
    NIH
    The Role of Canonical and Non-canonical Autophagy in B Cell Immunity
    Role: Principal Investigator

Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Melzi E, Willis JR, Ma KM, Lin YC, Kratochvil S, Berndsen ZT, Landais EA, Kalyuzhniy O, Nair U, Warner J, Steichen JM, Kalyuzhniy A, Le A, Pecetta S, Perez M, Kirsch K, Weldon SR, Falcone S, Himansu S, Carfi A, Sok D, Ward AB, Schief WR, Batista FD. Membrane-bound mRNA immunogens lower the threshold to activate HIV Env V2 apex-directed broadly neutralizing B cell precursors in humanized mice. Immunity. 2022 Nov 08; 55(11):2168-2186.e6. PMID: 36179690; PMCID: PMC9671093.
    Citations: 1     Fields:    Translation:HumansAnimalsCells
  2. Tas JMJ, Koo JH, Lin YC, Xie Z, Steichen JM, Jackson AM, Hauser BM, Wang X, Cottrell CA, Torres JL, Warner JE, Kirsch KH, Weldon SR, Groschel B, Nogal B, Ozorowski G, Bangaru S, Phelps N, Adachi Y, Eskandarzadeh S, Kubitz M, Burton DR, Lingwood D, Schmidt AG, Nair U, Ward AB, Schief WR, Batista FD. Antibodies from primary humoral responses modulate the recruitment of naive B cells during secondary responses. Immunity. 2022 10 11; 55(10):1856-1871.e6. PMID: 35987201; PMCID: PMC9350677.
    Citations: 1     Fields:    Translation:AnimalsCells
  3. Batista FD, Anderson KM, Böhm S, Del Alamo D, Dumstrei K, Gailite I, Klimmeck D, Teale W, Vodermaier H. The EMBO Journal at 40-here's to the future! EMBO J. 2022 01 04; 41(1):e110330. PMID: 34981519; PMCID: PMC8724766.
    Citations:    Fields:    
  4. Kratochvil S, Shen CH, Lin YC, Xu K, Nair U, Da Silva Pereira L, Tripathi P, Arnold J, Chuang GY, Melzi E, Schön A, Zhang B, Dillon M, Bonilla B, Flynn BJ, Kirsch KH, Kisalu NK, Kiyuka PK, Liu T, Ou L, Pancera M, Rawi R, Reveiz M, Seignon K, Wang LT, Waring MT, Warner J, Yang Y, Francica JR, Idris AH, Seder RA, Kwong PD, Batista FD. Vaccination in a humanized mouse model elicits highly protective PfCSP-targeting anti-malarial antibodies. Immunity. 2021 12 14; 54(12):2859-2876.e7. PMID: 34788599; PMCID: PMC9087378.
    Citations: 2     Fields:    Translation:HumansAnimalsCellsPHPublic Health
  5. Chapman JR, Barral P, Vannier JB, Borel V, Steger M, Tomas-Loba A, Sartori AA, Adams IR, Batista FD, Boulton SJ. RIF1 Is Essential for 53BP1-Dependent Nonhomologous End Joining and Suppression of DNA Double-Strand Break Resection. Mol Cell. 2021 Jul 01; 81(13):2868. PMID: 34214445.
    Citations: 1     Fields:    
  6. Batista FD. In conversation with the Chief Editor. EMBO J. 2021 04 15; 40(8):e108116. PMID: 33844305; PMCID: PMC8047437.
    Citations: 1     Fields:    
  7. Pulverer B, Batista FD. The fifth decade. EMBO J. 2021 04 15; 40(8):e108009. PMID: 33844313; PMCID: PMC8047435.
    Citations: 1     Fields:    
  8. Wang X, Ray R, Kratochvil S, Melzi E, Lin YC, Giguere S, Xu L, Warner J, Cheon D, Liguori A, Groschel B, Phelps N, Adachi Y, Tingle R, Wu L, Crotty S, Kirsch KH, Nair U, Schief WR, Batista FD. Multiplexed CRISPR/CAS9-mediated engineering of pre-clinical mouse models bearing native human B cell receptors. EMBO J. 2021 01 15; 40(2):e105926. PMID: 33258500.
    Citations: 6     Fields:    Translation:HumansAnimalsCells
  9. Janssen E, Tohme M, Butts J, Giguere S, Sage PT, Velázquez FE, Kam C, Milin E, Das M, Sobh A, Al-Tamemi S, Luscinskas FW, Batista F, Geha RS. DOCK8 is essential for LFA-1-dependent positioning of T follicular helper cells in germinal centers. JCI Insight. 2020 08 06; 5(15). PMID: 32573493.
    Citations: 4     Fields:    Translation:HumansAnimalsCells
  10. Steichen JM, Lin YC, Havenar-Daughton C, Pecetta S, Ozorowski G, Willis JR, Toy L, Sok D, Liguori A, Kratochvil S, Torres JL, Kalyuzhniy O, Melzi E, Kulp DW, Raemisch S, Hu X, Bernard SM, Georgeson E, Phelps N, Adachi Y, Kubitz M, Landais E, Umotoy J, Robinson A, Briney B, Wilson IA, Burton DR, Ward AB, Crotty S, Batista FD, Schief WR. A generalized HIV vaccine design strategy for priming of broadly neutralizing antibody responses. Science. 2019 12 06; 366(6470). PMID: 31672916.
    Citations: 76     Fields:    Translation:HumansAnimalsCells
  11. Farmer JR, Allard-Chamard H, Sun N, Ahmad M, Bertocchi A, Mahajan VS, Aicher T, Arnold J, Benson MD, Morningstar J, Barmettler S, Yuen G, Murphy SJH, Walter JE, Ghebremichael M, Shalek AK, Batista F, Gerszten R, Pillai S. Induction of metabolic quiescence defines the transitional to follicular B cell switch. Sci Signal. 2019 10 22; 12(604). PMID: 31641080.
    Citations: 9     Fields:    Translation:HumansAnimalsCells
  12. Tsui C, Maldonado P, Montaner B, Borroto A, Alarcon B, Bruckbauer A, Martinez-Martin N, Batista FD. Dynamic reorganisation of intermediate filaments coordinates early B-cell activation. Life Sci Alliance. 2018 Oct; 1(5):e201800060. PMID: 30456377; PMCID: PMC6238617.
    Citations: 5     Fields:    
  13. Lin YC, Pecetta S, Steichen JM, Kratochvil S, Melzi E, Arnold J, Dougan SK, Wu L, Kirsch KH, Nair U, Schief WR, Batista FD. One-step CRISPR/Cas9 method for the rapid generation of human antibody heavy chain knock-in mice. EMBO J. 2018 09 14; 37(18). PMID: 30087111; PMCID: PMC6138433.
    Citations: 15     Fields:    Translation:HumansAnimalsCells
  14. Keppler SJ, Burbage M, Gasparrini F, Hartjes L, Aggarwal S, Massaad MJ, Geha RS, Bruckbauer A, Batista FD. The Lack of WIP Binding to Actin Results in Impaired B Cell Migration and Altered Humoral Immune Responses. Cell Rep. 2018 07 17; 24(3):619-629. PMID: 30021160.
    Citations: 7     Fields:    Translation:AnimalsCells
  15. Tsui C, Martinez-Martin N, Gaya M, Maldonado P, Llorian M, Legrave NM, Rossi M, MacRae JI, Cameron AJ, Parker PJ, Leitges M, Bruckbauer A, Batista FD. Protein Kinase C-ß Dictates B Cell Fate by Regulating Mitochondrial Remodeling, Metabolic Reprogramming, and Heme Biosynthesis. Immunity. 2018 06 19; 48(6):1144-1159.e5. PMID: 29884460.
    Citations: 36     Fields:    Translation:AnimalsCells
  16. Burbage M, Gasparrini F, Aggarwal S, Gaya M, Arnold J, Nair U, Way M, Bruckbauer A, Batista FD. Tuning of in vivo cognate B-T cell interactions by Intersectin 2 is required for effective anti-viral B cell immunity. Elife. 2018 01 16; 7. PMID: 29337666; PMCID: PMC5770159.
    Citations: 8     Fields:    Translation:AnimalsCells
  17. Gaya M, Barral P, Burbage M, Aggarwal S, Montaner B, Warren Navia A, Aid M, Tsui C, Maldonado P, Nair U, Ghneim K, Fallon PG, Sekaly RP, Barouch DH, Shalek AK, Bruckbauer A, Strid J, Batista FD. Initiation of Antiviral B Cell Immunity Relies on Innate Signals from Spatially Positioned NKT Cells. Cell. 2018 01 25; 172(3):517-533.e20. PMID: 29249358.
    Citations: 74     Fields:    Translation:HumansAnimalsCells
  18. Nandin IS, Fong C, Deantonio C, Torreno-Pina JA, Pecetta S, Maldonado P, Gasparrini F, Ordovas-Montanes J, Kazer SW, Kjaer S, Borley DW, Nair U, Coleman JA, Lingwood D, Shalek AK, Meffre E, Poignard P, Burton DR, Batista FD. Correction: Novel in vitro booster vaccination to rapidly generate antigen-specific human monoclonal antibodies. J Exp Med. 2017 09 04; 214(9):2811. PMID: 28827449; PMCID: PMC5584127.
    Citations: 3     Fields:    
  19. Sanjuan Nandin I, Fong C, Deantonio C, Torreno-Pina JA, Pecetta S, Maldonado P, Gasparrini F, Ordovas-Montanes J, Kazer SW, Kjaer S, Borley DW, Nair U, Coleman JA, Lingwood D, Shalek AK, Meffre E, Poignard P, Burton DR, Batista FD. Novel in vitro booster vaccination to rapidly generate antigen-specific human monoclonal antibodies. J Exp Med. 2017 Aug 07; 214(8):2471-2490. PMID: 28739603.
    Citations: 6     Fields:    
  20. Burbage M, Keppler SJ, Montaner B, Mattila PK, Batista FD. The Small Rho GTPase TC10 Modulates B Cell Immune Responses. J Immunol. 2017 09 01; 199(5):1682-1695. PMID: 28747344; PMCID: PMC5563166.
    Citations: 10     Fields:    Translation:AnimalsCells
  21. Martinez-Martin N, Maldonado P, Gasparrini F, Frederico B, Aggarwal S, Gaya M, Tsui C, Burbage M, Keppler SJ, Montaner B, Jefferies HB, Nair U, Zhao YG, Domart MC, Collinson L, Bruckbauer A, Tooze SA, Batista FD. A switch from canonical to noncanonical autophagy shapes B cell responses. Science. 2017 02 10; 355(6325):641-647. PMID: 28183981; PMCID: PMC5805088.
    Citations: 43     Fields:    Translation:AnimalsCells
  22. Manno B, Oellerich T, Schnyder T, Corso J, Lösing M, Neumann K, Urlaub H, Batista FD, Engelke M, Wienands J. The Dok-3/Grb2 adaptor module promotes inducible association of the lipid phosphatase SHIP with the BCR in a coreceptor-independent manner. Eur J Immunol. 2016 11; 46(11):2520-2530. PMID: 27550373.
    Citations: 7     Fields:    Translation:AnimalsCells
  23. Kühn J, Wong LE, Pirkuliyeva S, Schulz K, Schwiegk C, Fünfgeld KG, Keppler S, Batista FD, Urlaub H, Habeck M, Becker S, Griesinger C, Wienands J. The adaptor protein CIN85 assembles intracellular signaling clusters for B cell activation. Sci Signal. 2016 06 28; 9(434):ra66. PMID: 27353366.
    Citations: 7     Fields:    Translation:HumansCells
  24. Calvo F, Ranftl R, Hooper S, Farrugia AJ, Moeendarbary E, Bruckbauer A, Batista F, Charras G, Sahai E. Cdc42EP3/BORG2 and Septin Network Enables Mechano-transduction and the Emergence of Cancer-Associated Fibroblasts. Cell Rep. 2015 Dec 29; 13(12):2699-714. PMID: 26711338.
    Citations: 48     Fields:    Translation:HumansAnimalsCells
  25. Gasparrini F, Feest C, Bruckbauer A, Mattila PK, Müller J, Nitschke L, Bray D, Batista FD. Nanoscale organization and dynamics of the siglec CD22 cooperate with the cytoskeleton in restraining BCR signalling. EMBO J. 2016 Feb 01; 35(3):258-80. PMID: 26671981.
    Citations: 40     Fields:    Translation:AnimalsCells
  26. Keppler SJ, Gasparrini F, Burbage M, Aggarwal S, Frederico B, Geha RS, Way M, Bruckbauer A, Batista FD. Wiskott-Aldrich Syndrome Interacting Protein Deficiency Uncovers the Role of the Co-receptor CD19 as a Generic Hub for PI3 Kinase Signaling in B Cells. Immunity. 2015 Oct 20; 43(4):660-73. PMID: 26453379.
    Citations: 29     Fields:    Translation:AnimalsCells
  27. Lu KH, Keppler S, Leithäuser F, Mattfeldt T, Castello A, Kostezka U, Küblbeck G, Schmitt S, Klevenz A, Prokosch S, Pougialis G, Pawson T, Batista F, Tafuri A, Arnold B. Nck adaptor proteins modulate differentiation and effector function of T cells. J Leukoc Biol. 2015 Sep; 98(3):301-11. PMID: 25995205.
    Citations: 2     Fields:    Translation:HumansAnimalsCells
  28. Gaya M, Castello A, Montaner B, Rogers N, Reis e Sousa C, Bruckbauer A, Batista FD. Host response. Inflammation-induced disruption of SCS macrophages impairs B cell responses to secondary infection. Science. 2015 Feb 06; 347(6222):667-72. PMID: 25657250.
    Citations: 63     Fields:    Translation:AnimalsCells
  29. Burbage M, Keppler SJ, Gasparrini F, Martínez-Martín N, Gaya M, Feest C, Domart MC, Brakebusch C, Collinson L, Bruckbauer A, Batista FD. Cdc42 is a key regulator of B cell differentiation and is required for antiviral humoral immunity. J Exp Med. 2015 Jan 12; 212(1):53-72. PMID: 25547673; PMCID: PMC4291523.
    Citations: 36     Fields:    Translation:AnimalsCells
  30. Castello A, Gaya M, Tucholski J, Oellerich T, Lu KH, Tafuri A, Pawson T, Wienands J, Engelke M, Batista FD. Nck-mediated recruitment of BCAP to the BCR regulates the PI(3)K-Akt pathway in B cells. Nat Immunol. 2013 Sep; 14(9):966-75. PMID: 23913047.
    Citations: 30     Fields:    Translation:AnimalsCells
  31. Mattila PK, Feest C, Depoil D, Treanor B, Montaner B, Otipoby KL, Carter R, Justement LB, Bruckbauer A, Batista FD. The actin and tetraspanin networks organize receptor nanoclusters to regulate B cell receptor-mediated signaling. Immunity. 2013 Mar 21; 38(3):461-74. PMID: 23499492.
    Citations: 150     Fields:    Translation:AnimalsCells
  32. Chapman JR, Barral P, Vannier JB, Borel V, Steger M, Tomas-Loba A, Sartori AA, Adams IR, Batista FD, Boulton SJ. RIF1 is essential for 53BP1-dependent nonhomologous end joining and suppression of DNA double-strand break resection. Mol Cell. 2013 Mar 07; 49(5):858-71. PMID: 23333305; PMCID: PMC3594748.
    Citations: 321     Fields:    Translation:HumansAnimalsCells
  33. Batista FD, Dustin ML. Cell:cell interactions in the immune system. Immunol Rev. 2013 Jan; 251(1):7-12. PMID: 23278736.
    Citations: 18     Fields:    Translation:HumansAnimalsCells
  34. Thaunat O, Batista FD. Daughter B cells are not created equal: asymmetric segregation of antigen during B cell division. Cell Cycle. 2012 Jun 15; 11(12):2219-20. PMID: 22617383; PMCID: PMC3383577.
    Citations: 3     Fields:    Translation:HumansCells
  35. Barral P, Sánchez-Niño MD, van Rooijen N, Cerundolo V, Batista FD. The location of splenic NKT cells favours their rapid activation by blood-borne antigen. EMBO J. 2012 May 16; 31(10):2378-90. PMID: 22505026; PMCID: PMC3364740.
    Citations: 46     Fields:    Translation:AnimalsCells
  36. Ahrens S, Zelenay S, Sancho D, Hanc P, Kjær S, Feest C, Fletcher G, Durkin C, Postigo A, Skehel M, Batista F, Thompson B, Way M, Reis e Sousa C, Schulz O. F-actin is an evolutionarily conserved damage-associated molecular pattern recognized by DNGR-1, a receptor for dead cells. Immunity. 2012 Apr 20; 36(4):635-45. PMID: 22483800.
    Citations: 175     Fields:    Translation:HumansAnimalsCells
  37. Harwood NE, Barral P, Batista FD. Neutrophils--the unexpected helpers of B-cell activation. EMBO Rep. 2012 Feb 01; 13(2):93-4. PMID: 22240972.
    Citations: 3     Fields:    Translation:HumansCells
  38. Thaunat O, Granja AG, Barral P, Filby A, Montaner B, Collinson L, Martinez-Martin N, Harwood NE, Bruckbauer A, Batista FD. Asymmetric segregation of polarized antigen on B cell division shapes presentation capacity. Science. 2012 Jan 27; 335(6067):475-9. PMID: 22282815.
    Citations: 60     Fields:    Translation:AnimalsCells
  39. Chang PP, Barral P, Fitch J, Pratama A, Ma CS, Kallies A, Hogan JJ, Cerundolo V, Tangye SG, Bittman R, Nutt SL, Brink R, Godfrey DI, Batista FD, Vinuesa CG. Identification of Bcl-6-dependent follicular helper NKT cells that provide cognate help for B cell responses. Nat Immunol. 2011 Nov 27; 13(1):35-43. PMID: 22120117.
    Citations: 144     Fields:    Translation:HumansAnimalsCells
  40. Oellerich T, Bremes V, Neumann K, Bohnenberger H, Dittmann K, Hsiao HH, Engelke M, Schnyder T, Batista FD, Urlaub H, Wienands J. The B-cell antigen receptor signals through a preformed transducer module of SLP65 and CIN85. EMBO J. 2011 Aug 05; 30(17):3620-34. PMID: 21822214.
    Citations: 27     Fields:    Translation:HumansAnimalsCells
  41. Schnyder T, Castello A, Feest C, Harwood NE, Oellerich T, Urlaub H, Engelke M, Wienands J, Bruckbauer A, Batista FD. B cell receptor-mediated antigen gathering requires ubiquitin ligase Cbl and adaptors Grb2 and Dok-3 to recruit dynein to the signaling microcluster. Immunity. 2011 Jun 24; 34(6):905-18. PMID: 21703542.
    Citations: 42     Fields:    Translation:AnimalsCells
  42. Treanor B, Depoil D, Bruckbauer A, Batista FD. Dynamic cortical actin remodeling by ERM proteins controls BCR microcluster organization and integrity. J Exp Med. 2011 May 09; 208(5):1055-68. PMID: 21482698.
    Citations: 81     Fields:    Translation:AnimalsCells
  43. Harwood NE, Batista FD. The cytoskeleton coordinates the early events of B-cell activation. Cold Spring Harb Perspect Biol. 2011 Feb 01; 3(2). PMID: 21047917.
    Citations: 48     Fields:    Translation:HumansCells
  44. Harwood NE, Batista FD. Antigen presentation to B cells. F1000 Biol Rep. 2010 Dec 17; 2:87. PMID: 21283653.
    Citations: 11     
  45. Batista FD, Treanor B, Harwood NE. Visualizing a role for the actin cytoskeleton in the regulation of B-cell activation. Immunol Rev. 2010 Sep; 237(1):191-204. PMID: 20727037.
    Citations: 26     Fields:    Translation:HumansAnimalsCells
  46. Cerundolo V, Barral P, Batista FD. Synthetic iNKT cell-agonists as vaccine adjuvants--finding the balance. Curr Opin Immunol. 2010 Jun; 22(3):417-24. PMID: 20471232.
    Citations: 17     Fields:    Translation:HumansAnimalsCells
  47. Henderson RB, Grys K, Vehlow A, de Bettignies C, Zachacz A, Henley T, Turner M, Batista F, Tybulewicz VL. A novel Rac-dependent checkpoint in B cell development controls entry into the splenic white pulp and cell survival. J Exp Med. 2010 Apr 12; 207(4):837-53. PMID: 20308364.
    Citations: 33     Fields:    Translation:AnimalsCells
  48. Barral P, Polzella P, Bruckbauer A, van Rooijen N, Besra GS, Cerundolo V, Batista FD. CD169(+) macrophages present lipid antigens to mediate early activation of iNKT cells in lymph nodes. Nat Immunol. 2010 Apr; 11(4):303-12. PMID: 20228797; PMCID: PMC2923071.
    Citations: 108     Fields:    Translation:AnimalsCells
  49. Treanor B, Depoil D, Gonzalez-Granja A, Barral P, Weber M, Dushek O, Bruckbauer A, Batista FD. The membrane skeleton controls diffusion dynamics and signaling through the B cell receptor. Immunity. 2010 Feb 26; 32(2):187-99. PMID: 20171124.
    Citations: 140     Fields:    Translation:AnimalsCells
  50. Harwood NE, Batista FD. Early events in B cell activation. Annu Rev Immunol. 2010; 28:185-210. PMID: 20192804.
    Citations: 149     Fields:    Translation:HumansAnimalsCells
  51. Randall KL, Lambe T, Johnson AL, Johnson A, Treanor B, Kucharska E, Domaschenz H, Whittle B, Tze LE, Enders A, Crockford TL, Bouriez-Jones T, Alston D, Cyster JG, Lenardo MJ, Mackay F, Deenick EK, Tangye SG, Chan TD, Camidge T, Brink R, Vinuesa CG, Batista FD, Cornall RJ, Goodnow CC. Dock8 mutations cripple B cell immunological synapses, germinal centers and long-lived antibody production. Nat Immunol. 2009 Dec; 10(12):1283-91. PMID: 19898472; PMCID: PMC3437189.
    Citations: 133     Fields:    Translation:HumansAnimalsCells
  52. Treanor B, Harwood NE, Batista FD. Microsignalosomes: spatially resolved receptor signalling. Biochem Soc Trans. 2009 Oct; 37(Pt 5):1014-8. PMID: 19754442.
    Citations: 10     Fields:    Translation:AnimalsCells
  53. Depoil D, Weber M, Treanor B, Fleire SJ, Carrasco YR, Harwood NE, Batista FD. Early events of B cell activation by antigen. Sci Signal. 2009 Mar 24; 2(63):pt1. PMID: 19318623.
    Citations: 21     Fields:    Translation:Cells
  54. Harwood NE, Batista FD. The antigen expressway: follicular conduits carry antigen to B cells. Immunity. 2009 Feb 20; 30(2):177-9. PMID: 19239901.
    Citations: 6     Fields:    Translation:Cells
  55. Eckl-Dorna J, Batista FD. BCR-mediated uptake of antigen linked to TLR9 ligand stimulates B-cell proliferation and antigen-specific plasma cell formation. Blood. 2009 Apr 23; 113(17):3969-77. PMID: 19144984.
    Citations: 67     Fields:    Translation:AnimalsCellsPHPublic Health
  56. Harwood NE, Batista FD. Visualizing the molecular and cellular events underlying the initiation of B-cell activation. Curr Top Microbiol Immunol. 2009; 334:153-77. PMID: 19521685.
    Citations: 12     Fields:    Translation:HumansAnimalsCells
  57. Fleire SJ, Batista FD. Studying cell-to-cell interactions: an easy method of tethering ligands on artificial membranes. Methods Mol Biol. 2009; 462:145-54. PMID: 19160666.
    Citations: 8     Fields:    Translation:AnimalsCells
  58. Batista FD, Harwood NE. The who, how and where of antigen presentation to B cells. Nat Rev Immunol. 2009 Jan; 9(1):15-27. PMID: 19079135.
    Citations: 259     Fields:    Translation:HumansAnimalsCells
  59. Meyer-Bahlburg A, Becker-Herman S, Humblet-Baron S, Khim S, Weber M, Bouma G, Thrasher AJ, Batista FD, Rawlings DJ. Wiskott-Aldrich syndrome protein deficiency in B cells results in impaired peripheral homeostasis. Blood. 2008 Nov 15; 112(10):4158-69. PMID: 18687984; PMCID: PMC2582000.
    Citations: 43     Fields:    Translation:AnimalsCells
  60. Batista F. Facundo Batista: watching B cells spread and grab antigens. Interview by Hema Bashyam. J Exp Med. 2008 Aug 04; 205(8):1718-9. PMID: 18678734; PMCID: PMC2525592.
    Citations:    Fields:    Translation:AnimalsCells
  61. Arana E, Harwood NE, Batista FD. Regulation of integrin activation through the B-cell receptor. J Cell Sci. 2008 Jul 15; 121(Pt 14):2279-86. PMID: 18596256.
    Citations: 25     Fields:    Translation:HumansAnimalsCells
  62. Barral P, Eckl-Dorna J, Harwood NE, De Santo C, Salio M, Illarionov P, Besra GS, Cerundolo V, Batista FD. B cell receptor-mediated uptake of CD1d-restricted antigen augments antibody responses by recruiting invariant NKT cell help in vivo. Proc Natl Acad Sci U S A. 2008 Jun 17; 105(24):8345-50. PMID: 18550831.
    Citations: 103     Fields:    Translation:AnimalsCellsPHPublic Health
  63. Harwood NE, Batista FD. New insights into the early molecular events underlying B cell activation. Immunity. 2008 May; 28(5):609-19. PMID: 18482567.
    Citations: 61     Fields:    Translation:HumansAnimalsCells
  64. Weber M, Treanor B, Depoil D, Shinohara H, Harwood NE, Hikida M, Kurosaki T, Batista FD. Phospholipase C-gamma2 and Vav cooperate within signaling microclusters to propagate B cell spreading in response to membrane-bound antigen. J Exp Med. 2008 Apr 14; 205(4):853-68. PMID: 18362175.
    Citations: 72     Fields:    Translation:AnimalsCells
  65. Lin KB, Freeman SA, Zabetian S, Brugger H, Weber M, Lei V, Dang-Lawson M, Tse KW, Santamaria R, Batista FD, Gold MR. The rap GTPases regulate B cell morphology, immune-synapse formation, and signaling by particulate B cell receptor ligands. Immunity. 2008 Jan; 28(1):75-87. PMID: 18191594.
    Citations: 34     Fields:    Translation:HumansAnimalsCells
  66. Arana E, Vehlow A, Harwood NE, Vigorito E, Henderson R, Turner M, Tybulewicz VL, Batista FD. Activation of the small GTPase Rac2 via the B cell receptor regulates B cell adhesion and immunological-synapse formation. Immunity. 2008 Jan; 28(1):88-99. PMID: 18191593.
    Citations: 68     Fields:    Translation:AnimalsCells
  67. Depoil D, Fleire S, Treanor BL, Weber M, Harwood NE, Marchbank KL, Tybulewicz VL, Batista FD. CD19 is essential for B cell activation by promoting B cell receptor-antigen microcluster formation in response to membrane-bound ligand. Nat Immunol. 2008 Jan; 9(1):63-72. PMID: 18059271.
    Citations: 158     Fields:    Translation:AnimalsCells
  68. Batista FD, Arana E, Barral P, Carrasco YR, Depoil D, Eckl-Dorna J, Fleire S, Howe K, Vehlow A, Weber M, Treanor B. The role of integrins and coreceptors in refining thresholds for B-cell responses. Immunol Rev. 2007 Aug; 218:197-213. PMID: 17624954.
    Citations: 8     Fields:    Translation:HumansAnimalsCells
  69. Treanor B, Batista FD. Mechanistic insight into lymphocyte activation through quantitative imaging and theoretical modelling. Curr Opin Immunol. 2007 Aug; 19(4):476-83. PMID: 17659866.
    Citations: 9     Fields:    Translation:Cells
  70. Carrasco YR, Batista FD. B cells acquire particulate antigen in a macrophage-rich area at the boundary between the follicle and the subcapsular sinus of the lymph node. Immunity. 2007 Jul; 27(1):160-71. PMID: 17658276.
    Citations: 265     Fields:    Translation:AnimalsCells
  71. McCarthy C, Shepherd D, Fleire S, Stronge VS, Koch M, Illarionov PA, Bossi G, Salio M, Denkberg G, Reddington F, Tarlton A, Reddy BG, Schmidt RR, Reiter Y, Griffiths GM, van der Merwe PA, Besra GS, Jones EY, Batista FD, Cerundolo V. The length of lipids bound to human CD1d molecules modulates the affinity of NKT cell TCR and the threshold of NKT cell activation. J Exp Med. 2007 May 14; 204(5):1131-44. PMID: 17485514; PMCID: PMC2118584.
    Citations: 121     Fields:    Translation:HumansCells
  72. Fleire SJ, Goldman JP, Carrasco YR, Weber M, Bray D, Batista FD. B cell ligand discrimination through a spreading and contraction response. Science. 2006 May 05; 312(5774):738-41. PMID: 16675699.
    Citations: 174     Fields:    Translation:AnimalsCells
  73. Carrasco YR, Batista FD. B cell recognition of membrane-bound antigen: an exquisite way of sensing ligands. Curr Opin Immunol. 2006 Jun; 18(3):286-91. PMID: 16616474.
    Citations: 43     Fields:    Translation:HumansAnimalsCells
  74. Carrasco YR, Batista FD. B-cell activation by membrane-bound antigens is facilitated by the interaction of VLA-4 with VCAM-1. EMBO J. 2006 Feb 22; 25(4):889-99. PMID: 16456548; PMCID: PMC1383545.
    Citations: 57     Fields:    Translation:AnimalsCells
  75. Smith A, Carrasco YR, Stanley P, Kieffer N, Batista FD, Hogg N. A talin-dependent LFA-1 focal zone is formed by rapidly migrating T lymphocytes. J Cell Biol. 2005 Jul 04; 170(1):141-51. PMID: 15983060; PMCID: PMC2171377.
    Citations: 85     Fields:    Translation:HumansCells
  76. Carrasco YR, Fleire SJ, Cameron T, Dustin ML, Batista FD. LFA-1/ICAM-1 interaction lowers the threshold of B cell activation by facilitating B cell adhesion and synapse formation. Immunity. 2004 May; 20(5):589-99. PMID: 15142527.
    Citations: 148     Fields:    Translation:AnimalsCells
  77. Lanoue A, Batista FD, Stewart M, Neuberger MS. Interaction of CD22 with alpha2,6-linked sialoglycoconjugates: innate recognition of self to dampen B cell autoreactivity? Eur J Immunol. 2002 02; 32(2):348-55. PMID: 11807774.
    Citations: 39     Fields:    Translation:AnimalsCells
  78. de Fougerolles AR, Batista F, Johnsson E, Fearon DT. IgM and stromal cell-associated heparan sulfate/heparin as complement-independent ligands for CD19. Eur J Immunol. 2001 Jul; 31(7):2189-99. PMID: 11449373.
    Citations: 6     Fields:    Translation:AnimalsCells
  79. Batista FD, Iber D, Neuberger MS. B cells acquire antigen from target cells after synapse formation. Nature. 2001 May 24; 411(6836):489-94. PMID: 11373683.
    Citations: 212     Fields:    Translation:HumansAnimalsCells
  80. Batista FD, Neuberger MS. B cells extract and present immobilized antigen: implications for affinity discrimination. EMBO J. 2000 Feb 15; 19(4):513-20. PMID: 10675320; PMCID: PMC305589.
    Citations: 62     Fields:    Translation:AnimalsCells
  81. Neuberger MS, Lanoue A, Ehrenstein MR, Batista FD, Sale JE, Williams GT. Antibody diversification and selection in the mature B-cell compartment. Cold Spring Harb Symp Quant Biol. 1999; 64:211-6. PMID: 11232288.
    Citations: 5     Fields:    Translation:HumansAnimalsCells
  82. Batista FD, Neuberger MS. Affinity dependence of the B cell response to antigen: a threshold, a ceiling, and the importance of off-rate. Immunity. 1998 Jun; 8(6):751-9. PMID: 9655489.
    Citations: 172     Fields:    Translation:AnimalsCells
  83. Batista FD, Anand S, Presani G, Efremov DG, Burrone OR. The two membrane isoforms of human IgE assemble into functionally distinct B cell antigen receptors. J Exp Med. 1996 Dec 01; 184(6):2197-205. PMID: 8976175; PMCID: PMC2196392.
    Citations: 11     Fields:    Translation:HumansCells
  84. Batista FD, Efremov DG, Burrone OR. Characterization of a second secreted IgE isoform and identification of an asymmetric pathway of IgE assembly. Proc Natl Acad Sci U S A. 1996 Apr 16; 93(8):3399-404. PMID: 8622947; PMCID: PMC39620.
    Citations: 4     Fields:    Translation:HumansAnimalsCells
  85. Batista FD, Efremov DG, Burrone OR. Characterization and expression of alternatively spliced IgE heavy chain transcripts produced by peripheral blood lymphocytes. J Immunol. 1995 Jan 01; 154(1):209-18. PMID: 7995941.
    Citations: 10     Fields:    Translation:HumansAnimalsCells
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.