Harvard Catalyst Profiles

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Peng Li, Ph.D.

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Biography
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2016
2016 Partners Healthcare Innovation Discovery, Partners Healthcare (now Mass General Brigham)
2018
Trainee Professional Development Award, Society for Neuroscience
2019
Brigham Research Institute Microgrant Award, Brigham and Women's Hospital
2020
1st place of Club Hypnos Cup Data Blitz competition (virtual due to COVID19), Sleep Research Society
2020
Travel Award, the International Workshop on HIV & Aging (converted to fee waiver due to COVID 19)
2021
Young Investigators Research Forum Award, American Academy of Sleep Medicine
2022
Early Career Mentoring Award, Brigham and Women's Hospital Department of Medicine
2024
Nominated for the Excellence in Mentoring Awards, Harvard Medical School

Overview
overview
Dr. Li is a biomedical engineer and computational physiologist with a cross-disciplinary background in biomedical signal processing, physiological measurement, sleep and circadian physiology, and neurophysiology research. Dr. Li directs the Laboratory for Sleep and Digital Health (LSDH) and serves as the Research Director of the Medical Biodynamics Center (MBC). While his primary focus is on research, Dr. Li is equally passionate about teaching and mentoring others—a pursuit he considers essential to his professional and personal growth. Dr. Li was honored to receive the 2022 Early Career Mentoring Award from the Department of Medicine at Brigham and Women’s Hospital. Additionally, Dr. Li is privileged to serve on the Editorial Board of the journal SLEEP and as an Assistant Editor for the Journal of the American Heart Association.

In LSDH, the research focuses on identifying individuals at elevated risk of cognitive impairment, Alzheimer’s disease, and related dementias by utilizing novel digital biomarkers linked to sleep and circadian rhythms. The LSDH also investigates the role of sleep and circadian regulation in cognitive function and resilience across diverse populations, with a special emphasis on vulnerable and underrepresented groups. To support individualized, proactive management of sleep and circadian health, the LSDH is also dedicated to developing innovative, cost-effective, and non-invasive contactless monitoring solutions including cutting-edge products and algorithms.
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Research
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The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
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  1. (LI, PENG) Jun 1, 2023 - May 31, 2024
    Brigham Research Institute
    Circadian rest-activity rhythms and links with cognitive function in women aging with HIV
    Role: Principal Investigator
  2. 290-FP-22 (GAO, CHENLU) Jan 1, 2023 - Dec 31, 2023
    American Academy of Sleep Medicine
    Daytime napping and Alzheimer's disease in middle-to-older aged adults: Timing, irregularity, and interaction with genetic risks
    Role: Primary Mentor
  3. AARFD-22-928372 (GAO, CHENLU) Mar 1, 2022 - Feb 28, 2025
    Alzheimer's Association
    Timing and irregularity of daytime napping and Alzheimer’s disease
    Role: Primary Mentor
  4. UWSC12802 (LI, PENG) May 1, 2021 - Oct 31, 2022
    NIH/NIA
    Association between rest activity circadian rhythm and cognition in PLWH
    Role: Principal Investigator
  5. CFAR-BWH-21-1-LI (LI, PENG) Feb 1, 2021 - May 31, 2022
    Harvard University Center for AIDS Research
    Circadian disturbances and cognitive impairment in people living with HIV
    Role: Principal Investigator

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© 2025 President and Fellows of Harvard College
Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.