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profileTimothy Houle, Ph.D.

TitleMember of the Faculty of Anaesthesia
InstitutionMassachusetts General Hospital
DepartmentAnaesthesia
AddressMassachusetts General Hospital
55 Fruit St
Boston MA 02114
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The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
P01GM113852     (EISENACH, JAMES)Apr 1, 2016 - Mar 31, 2021
NIH/NIGMS
Recovery from Pain and Disability after Surgery
Role: Co-Principal Investigator

R01NS065257     (HOULE, TIMOTHY T)May 15, 2009 - Jun 30, 2019
NIH/NINDS
Physiological Arousal and Headache
Role: Principal Investigator

M01RR007122     (APPLEGATE, WILLIAM B)Sep 30, 1992 - Aug 28, 2011
NIH/NCRR
General Clinical Research Center
Role: Co-Principal Investigator

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Collapse selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Parker MJ, Lovich MA, Tsao AC, Deng H, Houle T, Peterfreund RA. Novel Pump Control Technology Accelerates Drug Delivery Onset in a Model of Pediatric Drug Infusion. Anesth Analg. 2017 Apr; 124(4):1129-1134. PMID: 28181934.
    View in: PubMed
  2. Eikermann M, Schaller SJ, Kasotakis G, Anstey M, Houle T. Early goal-directed mobilisation after surgery - Authors' reply. Lancet. 2017 Feb 18; 389(10070):695-696. PMID: 28229868.
    View in: PubMed
  3. Eisenach JC, Curry R, Aschenbrenner CA, Coghill RC, Houle TT. Pupil responses and pain ratings to heat stimuli: Reliability and effects of expectations and a conditioning pain stimulus. J Neurosci Methods. 2017 Mar 01; 279:52-59. PMID: 28089758.
    View in: PubMed
  4. Timm FP, Houle TT, Grabitz SD, Lihn AL, Stokholm JB, Eikermann-Haerter K, Nozari A, Kurth T, Eikermann M. Migraine and risk of perioperative ischemic stroke and hospital readmission: hospital based registry study. BMJ. 2017 Jan 10; 356:i6635. PMID: 28073753.
    View in: PubMed
  5. Schaller S, Blobner M, Grabitz S, Heim M, Houle T, Mazwi N, Walz M, Eikermann M. 1518: INFLUENCE OF GLASGOW COMA SCALE ON EARLY, GOAL-DIRECTED MOBILIZATION EFFECTS. Crit Care Med. 2016 Dec; 44(12 Suppl 1):455. PMID: 27851154.
    View in: PubMed
  6. Amlong CA, Perkins MG, Houle TT, Miller KW, Pearce RA. Contrasting Effects of the ?-Aminobutyric Acid Type A Receptor ß3 Subunit N265M Mutation on Loss of Righting Reflexes Induced by Etomidate and the Novel Anesthetic Barbiturate R-mTFD-MPAB. Anesth Analg. 2016 Nov; 123(5):1241-1246. PMID: 27331778.
    View in: PubMed
  7. Schaller SJ, Anstey M, Blobner M, Edrich T, Grabitz SD, Gradwohl-Matis I, Heim M, Houle T, Kurth T, Latronico N, Lee J, Meyer MJ, Peponis T, Talmor D, Velmahos GC, Waak K, Walz JM, Zafonte R, Eikermann M. Early, goal-directed mobilisation in the surgical intensive care unit: a randomised controlled trial. Lancet. 2016 Oct 01; 388(10052):1377-1388. PMID: 27707496.
    View in: PubMed
  8. Turner DP, Golding AN, Houle TT. Using a graphical risk tool to examine willingness to take migraine prophylactic medications. Pain. 2016 Oct; 157(10):2226-2234. PMID: 27820159.
    View in: PubMed
  9. Eisenach JC, Kheterpal S, Houle TT. Reporting of Observational Research in ANESTHESIOLOGY: The Importance of the Analysis Plan. Anesthesiology. 2016 May; 124(5):998-1000. PMID: 26933796.
    View in: PubMed
  10. Miller AN, Deal D, Green J, Houle T, Brown W, Thore C, Stump D, Webb LX. Use of the Reamer/Irrigator/Aspirator Decreases Carotid and Cranial Embolic Events in a Canine Model. J Bone Joint Surg Am. 2016 Apr 20; 98(8):658-64. PMID: 27098324.
    View in: PubMed
  11. Eisenach JC, Warner DS, Houle TT. Reporting of Preclinical Research in Anesthesiology: Transparency and Enforcement. Anesthesiology. 2016 Apr; 124(4):763-5. PMID: 26845144.
    View in: PubMed
  12. Smitherman TA, Walters AB, Davis RE, Ambrose CE, Roland M, Houle TT, Rains JC. Randomized Controlled Pilot Trial of Behavioral Insomnia Treatment for Chronic Migraine With Comorbid Insomnia. Headache. 2016 Feb; 56(2):276-91. PMID: 26813845.
    View in: PubMed
  13. Adams LW, Aschenbrenner CA, Houle TT, Roy RC. Uncovering the History of Operating Room Attire through Photographs. Anesthesiology. 2016 Jan; 124(1):19-24. PMID: 26569168.
    View in: PubMed
  14. Irby MB, Bond DS, Lipton RB, Nicklas B, Houle TT, Penzien DB. Aerobic Exercise for Reducing Migraine Burden: Mechanisms, Markers, and Models of Change Processes. Headache. 2016 Feb; 56(2):357-69. PMID: 26643584; PMCID: PMC4813301.
  15. Houle TT. An Innovative Analysis of Analgesic Consumption in the Postoperative Period. Anesthesiology. 2015 Dec; 123(6):1227-8. PMID: 26495979.
    View in: PubMed
  16. Bellinger CR, Chatterjee AB, Adair N, Houle T, Khan I, Haponik E. Authors' Reply. Respiration. 2015; 90(2):174. PMID: 26160443.
    View in: PubMed
  17. Penzien DB, Irby MB, Smitherman TA, Rains JC, Houle TT. Well-Established and Empirically Supported Behavioral Treatments for Migraine. Curr Pain Headache Rep. 2015 Jul; 19(7):34. PMID: 26065542.
    View in: PubMed
  18. Turner DP, Smitherman TA, Black AK, Penzien DB, Porter JA, Lofland KR, Houle TT. Are migraine and tension-type headache diagnostic types or points on a severity continuum? An exploration of the latent taxometric structure of headache. Pain. 2015 Jul; 156(7):1200-7. PMID: 25775357; PMCID: PMC4524296.
  19. Peters CM, Hayashida K, Suto T, Houle TT, Aschenbrenner CA, Martin TJ, Eisenach JC. Individual differences in acute pain-induced endogenous analgesia predict time to resolution of postoperative pain in the rat. Anesthesiology. 2015 Apr; 122(4):895-907. PMID: 25581910; PMCID: PMC4366291.
  20. Brown CL, Irby MB, Houle TT, Skelton JA. Family-based obesity treatment in children with disabilities. Acad Pediatr. 2015 Mar-Apr; 15(2):197-203. PMID: 25748977; PMCID: PMC4355477 [Available on 03/01/16].
  21. Bellinger CR, Chatterjee AB, Adair N, Houle T, Khan I, Haponik E. Training in and experience with endobronchial ultrasound. Respiration. 2014; 88(6):478-83. PMID: 25402619.
    View in: PubMed
  22. Aschenbrenner CA, Houle TT, Gutierrez S, Eisenach JC. Modeling individual recovery after peripheral nerve injury in rats and the effects of parturition. Anesthesiology. 2014 Nov; 121(5):1056-67. PMID: 24979387; PMCID: PMC4276146.
  23. Smitherman TA, Davis RE, Walters AB, Young J, Houle TT. Anxiety sensitivity and headache: diagnostic differences, impact, and relations with perceived headache triggers. Cephalalgia. 2015 Jul; 35(8):710-21. PMID: 25352500.
    View in: PubMed
  24. Rothrock JF, Bloudek LM, Houle TT, Andress-Rothrock D, Varon SF. Real-world economic impact of onabotulinumtoxinA in patients with chronic migraine. Headache. 2014 Nov-Dec; 54(10):1565-73. PMID: 25298117; PMCID: PMC4282490.
  25. Boada MD, Gutierrez S, Aschenbrenner CA, Houle TT, Hayashida K, Ririe DG, Eisenach JC. Nerve injury induces a new profile of tactile and mechanical nociceptor input from undamaged peripheral afferents. J Neurophysiol. 2015 Jan 01; 113(1):100-9. PMID: 25274350; PMCID: PMC4294562 [Available on 01/01/16].
  26. Boada MD, Martin TJ, Peters CM, Hayashida K, Harris MH, Houle TT, Boyden ES, Eisenach JC, Ririe DG. Fast-conducting mechanoreceptors contribute to withdrawal behavior in normal and nerve injured rats. Pain. 2014 Dec; 155(12):2646-55. PMID: 25267211; PMCID: PMC4374598.
  27. Eisenach JC, Houle TT. Replication to advance science: changes in ANESTHESIOLOGY. Anesthesiology. 2014 Aug; 121(2):209-11. PMID: 24895916.
    View in: PubMed
  28. Wells RE, Burch R, Paulsen RH, Wayne PM, Houle TT, Loder E. Meditation for migraines: a pilot randomized controlled trial. Headache. 2014 Oct; 54(9):1484-95. PMID: 25041058.
    View in: PubMed
  29. Turner KR, Fisher EC, Hade EM, Houle TT, Rocco MV. The role of perioperative sodium bicarbonate infusion affecting renal function after cardiothoracic surgery. Front Pharmacol. 2014; 5:127. PMID: 24917818; PMCID: PMC4040918.
  30. Mason KP, Turner DP, Houle TT, Fontaine PJ, Lerman J. Hemodynamic response to fluid management in children undergoing dexmedetomidine sedation for MRI. AJR Am J Roentgenol. 2014 Jun; 202(6):W574-9. PMID: 24848852.
    View in: PubMed
  31. Wells RE, Smitherman TA, Seng EK, Houle TT, Loder EW. Behavioral and mind/body interventions in headache: unanswered questions and future research directions. Headache. 2014 Jun; 54(6):1107-13. PMID: 24735261.
    View in: PubMed
  32. Peters CM, Ririe D, Houle TT, Aschenbrenner CA, Eisenach JC. Nociceptor-selective peripheral nerve block induces delayed mechanical hypersensitivity and neurotoxicity in rats. Anesthesiology. 2014 Apr; 120(4):976-86. PMID: 24296762.
    View in: PubMed
  33. Sher T, Braun L, Domas A, Bellg A, Baucom DH, Houle TT. The partners for life program: a couples approach to cardiac risk reduction. Fam Process. 2014 Mar; 53(1):131-49. PMID: 24495204; PMCID: PMC3959575.
  34. Turner DP, Smitherman TA, Penzien DB, Porter JA, Martin VT, Houle TT. Nighttime snacking, stress, and migraine activity. J Clin Neurosci. 2014 Apr; 21(4):638-43. PMID: 24417796; PMCID: PMC3959563.
  35. McDermott MJ, Tull MT, Gratz KL, Houle TT, Smitherman TA. Comorbidity of migraine and psychiatric disorders among substance-dependent inpatients. Headache. 2014 Feb; 54(2):290-302. PMID: 23848988.
    View in: PubMed
  36. Houle TT, Turner DP. Bayesian statistical inference in anesthesiology. Anesthesiology. 2013 Jul; 119(1):4-6. PMID: 23648520.
    View in: PubMed
  37. Houle TT, Turner DP, Penzien DB. Type I error in headache research. Headache. 2013 Jul-Aug; 53(7):1031-3. PMID: 23773114.
    View in: PubMed
  38. Houle TT, Turner DP, Houle TA, Smitherman TA, Martin V, Penzien DB, Lipton RB. Rounding behavior in the reporting of headache frequency complicates headache chronification research. Headache. 2013 Jun; 53(6):908-19. PMID: 23721238; PMCID: PMC4546843.
  39. Houle TT, Turner DP, Smitherman TA, Penzien DB, Lipton RB. Influence of random measurement error on estimated rates of headache chronification and remission. Headache. 2013 Jun; 53(6):920-9. PMID: 23721239.
    View in: PubMed
  40. Lipton RB, Penzien DB, Turner DP, Smitherman TA, Houle TT. Methodological issues in studying rates and predictors of migraine progression and remission. Headache. 2013 Jun; 53(6):930-4. PMID: 23721240.
    View in: PubMed
  41. Turner DP, Smitherman TA, Penzien DB, Lipton RB, Houle TT. Rethinking headache chronification. Headache. 2013 Jun; 53(6):901-7. PMID: 23721237; PMCID: PMC4546844.
  42. Pan PH, Tonidandel AM, Aschenbrenner CA, Houle TT, Harris LC, Eisenach JC. Predicting acute pain after cesarean delivery using three simple questions. Anesthesiology. 2013 May; 118(5):1170-9. PMID: 23485992; PMCID: PMC3951732.
  43. Houle TT, Turner DP. Natural experimentation is a challenging method for identifying headache triggers. Headache. 2013 Apr; 53(4):636-43. PMID: 23534852.
    View in: PubMed
  44. Turner DP, Smitherman TA, Martin VT, Penzien DB, Houle TT. Causality and headache triggers. Headache. 2013 Apr; 53(4):628-35. PMID: 23534872; PMCID: PMC3628761.
  45. Martin GV, Houle T, Nicholson R, Peterlin A, Martin VT. Lightning and its association with the frequency of headache in migraineurs: an observational cohort study. Cephalalgia. 2013 Apr; 33(6):375-83. PMID: 23349357.
    View in: PubMed
  46. Gutierrez S, Liu B, Hayashida K, Houle TT, Eisenach JC. Reversal of peripheral nerve injury-induced hypersensitivity in the postpartum period: role of spinal oxytocin. Anesthesiology. 2013 Jan; 118(1):152-9. PMID: 23249932; PMCID: PMC3876486.
  47. Eisenach JC, Pan P, Smiley RM, Lavand'homme P, Landau R, Houle TT. Resolution of pain after childbirth. Anesthesiology. 2013 Jan; 118(1):143-51. PMID: 23249931; PMCID: PMC3876485.
  48. Turner DP, Houle TT. Psychological evaluation of a primary headache patient. Pain Manag. 2013 Jan 01; 3(1):19-25. PMID: 23418407.
    View in: PubMed
  49. Galovski TE, Blain LM, Mott JM, Elwood L, Houle T. Manualized therapy for PTSD: flexing the structure of cognitive processing therapy. J Consult Clin Psychol. 2012 Dec; 80(6):968-81. PMID: 23106761; PMCID: PMC3538790.
  50. Tegeler CH, Kumar SR, Conklin D, Lee SW, Gerdes L, Turner DP, Tegeler CL, C Fidali B, Houle TT. Open label, randomized, crossover pilot trial of high-resolution, relational, resonance-based, electroencephalic mirroring to relieve insomnia. Brain Behav. 2012 Nov; 2(6):814-24. PMID: 23170244; PMCID: PMC3500468.
  51. Houle TT, Butschek RA, Turner DP, Smitherman TA, Rains JC, Penzien DB. Stress and sleep duration predict headache severity in chronic headache sufferers. Pain. 2012 Dec; 153(12):2432-40. PMID: 23073072; PMCID: PMC3626265.
  52. King RB, Hartke RJ, Houle T, Lee J, Herring G, Alexander-Peterson BS, Raad J. A problem-solving early intervention for stroke caregivers: one year follow-up. Rehabil Nurs. 2012 Sep-Oct; 37(5):231-43. PMID: 22949276; PMCID: PMC4060889.
  53. Turner DP, Smitherman TA, Eisenach JC, Penzien DB, Houle TT. Predictors of headache before, during, and after pregnancy: a cohort study. Headache. 2012 Mar; 52(3):348-62. PMID: 22268840; PMCID: PMC3299832.
  54. Houle TT, Turner DP, Penzien DB. How does the migraine attack stop? It is NOT the trigger: common headache triggers do not predict cessation of pain. Headache. 2012 Jan; 52(1):189-90. PMID: 22221183; PMCID: PMC3265576.
  55. McCormick JG, Houle TT, Saltzman HA, Whaley RC, Roy RC. Treatment of acute stroke with hyperbaric oxygen: time window for efficacy. Undersea Hyperb Med. 2011 Sep-Oct; 38(5):321-34. PMID: 22013759.
    View in: PubMed
  56. Boada MD, Gutierrez S, Houle T, Eisenach JC, Ririe DG. Developmental differences in peripheral glabrous skin mechanosensory nerve receptive field and intracellular electrophysiologic properties: phenotypic characterization in infant and juvenile rats. Int J Dev Neurosci. 2011 Dec; 29(8):847-54. PMID: 21856407; PMCID: PMC3381879.
  57. Schafer AM, Rains JC, Penzien DB, Groban L, Smitherman TA, Houle TT. Direct costs of preventive headache treatments: comparison of behavioral and pharmacologic approaches. Headache. 2011 Jun; 51(6):985-91. PMID: 21631481; PMCID: PMC3303196.
  58. Brock MF, Grace BE, Morley B, Hillegass G, Houle TT, Groban L. Does lidocaine more effectively prevent pain upon induction with propofol or etomidate when given preemptively than when mixed with the drug? J Clin Anesth. 2010 Nov; 22(7):505-9. PMID: 21056806.
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  59. Hadzic A, Houle TT, Capdevila X, Ilfeld BM. Femoral nerve block for analgesia in patients having knee arthroplasty. Anesthesiology. 2010 Nov; 113(5):1014-5. PMID: 20881593.
    View in: PubMed
  60. Boada MD, Houle TT, Eisenach JC, Ririe DG. Differing neurophysiologic mechanosensory input from glabrous and hairy skin in juvenile rats. J Neurophysiol. 2010 Dec; 104(6):3568-75. PMID: 20926608; PMCID: PMC3007645.
  61. Reed J, deShazo RD, Houle TT, Stringer S, Wright L, Moak JS. Clinical features of sarcoid rhinosinusitis. Am J Med. 2010 Sep; 123(9):856-62. PMID: 20800155.
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  62. King RB, Hartke RJ, Houle TT. Patterns of relationships between background characteristics, coping, and stroke caregiver outcomes. Top Stroke Rehabil. 2010 Jul-Aug; 17(4):308-17. PMID: 20826419; PMCID: PMC3148896.
  63. Starr CJ, Houle TT, Coghill RC. Psychological and sensory predictors of experimental thermal pain: a multifactorial model. J Pain. 2010 Dec; 11(12):1394-402. PMID: 20570569; PMCID: PMC2954262.
  64. Eisenach JC, Curry R, Tong C, Houle TT, Yaksh TL. Effects of intrathecal ketorolac on human experimental pain. Anesthesiology. 2010 May; 112(5):1216-24. PMID: 20395821; PMCID: PMC2924167.
  65. Ray P, Le Manach Y, Riou B, Houle TT. Statistical evaluation of a biomarker. Anesthesiology. 2010 Apr; 112(4):1023-40. PMID: 20234303.
    View in: PubMed
  66. Jain RK, Antonio BL, Bowton DL, Houle TT, MacGregor DA. Variability in central venous pressure measurements and the potential impact on fluid management. Shock. 2010 Mar; 33(3):253-7. PMID: 19543151.
    View in: PubMed
  67. Groban L, Sanders DM, Houle TT, Antonio BL, Ntuen EC, Zvara DA, Kon ND, Kincaid EH. Prognostic value of tissue Doppler-Derived E/e' on early morbid events after cardiac surgery. Echocardiography. 2010 Feb; 27(2):131-8. PMID: 20380676; PMCID: PMC4451185.
  68. Nelson KE, Houle TT, Eisenach JC. Blood pressure, but not cerebrospinal fluid fentanyl concentration, predicts duration of labor analgesia from spinal fentanyl. Anesthesiology. 2010 Jan; 112(1):174-80. PMID: 19996953.
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  69. Sinha SK, Abrams JH, Houle TT, Weller RS. Ultrasound-guided obturator nerve block: an interfascial injection approach without nerve stimulation. Reg Anesth Pain Med. 2009 May-Jun; 34(3):261-4. PMID: 19587627.
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  70. Houle TT. Reporting the results of a study that did not go according to plan. Anesthesiology. 2009 May; 110(5):957-8. PMID: 19387171.
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  71. Milne CT, Trigilia D, Houle TL, Delong S, Rosenblum D. Reducing pressure ulcer prevalence rates in the long-term acute care setting. Ostomy Wound Manage. 2009 Apr; 55(4):50-9. PMID: 19387096.
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  72. Miano TA, Reichert MG, Houle TT, MacGregor DA, Kincaid EH, Bowton DL. Nosocomial pneumonia risk and stress ulcer prophylaxis: a comparison of pantoprazole vs ranitidine in cardiothoracic surgery patients. Chest. 2009 Aug; 136(2):440-7. PMID: 19318661.
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  73. Lerman J, Houle TT, Matthews BT, Houck J, Burrows FA. Propofol for tracheal intubation in children anesthetized with sevoflurane: a dose-response study. Paediatr Anaesth. 2009 Mar; 19(3):218-24. PMID: 19236643.
    View in: PubMed
  74. Ramsdell R, Lerman J, Pickhardt D, Feldman D, Foster J, Houle TT. Subspecialty impact factors: the contribution of pediatric anesthesia and pain articles. Anesth Analg. 2009 Jan; 108(1):105-10. PMID: 19095837.
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  75. Harden RN, Cottrill J, Gagnon CM, Smitherman TA, Weinland SR, Tann B, Joseph P, Lee TS, Houle TT. Botulinum toxin a in the treatment of chronic tension-type headache with cervical myofascial trigger points: a randomized, double-blind, placebo-controlled pilot study. Headache. 2009 May; 49(5):732-43. PMID: 19178577.
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  76. Eisenach JC, Pan PH, Smiley R, Lavand'homme P, Landau R, Houle TT. Severity of acute pain after childbirth, but not type of delivery, predicts persistent pain and postpartum depression. Pain. 2008 Nov 15; 140(1):87-94. PMID: 18818022; PMCID: PMC2605246.
  77. Groban L, Jobe H, Lin M, Houle T, Kitzman DA, Sonntag W. Effects of short-term treadmill exercise training or growth hormone supplementation on diastolic function and exercise tolerance in old rats. J Gerontol A Biol Sci Med Sci. 2008 Sep; 63(9):911-20. PMID: 18840795; PMCID: PMC2821700.
  78. Houle TT, Stump DA. Statistical significance versus clinical significance. Semin Cardiothorac Vasc Anesth. 2008 Mar; 12(1):5-6. PMID: 18403377.
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  79. Groban L, Yamaleyeva LM, Westwood BM, Houle TT, Lin M, Kitzman DW, Chappell MC. Progressive diastolic dysfunction in the female mRen(2). Lewis rat: influence of salt and ovarian hormones. J Gerontol A Biol Sci Med Sci. 2008 Jan; 63(1):3-11. PMID: 18245755.
    View in: PubMed
  80. Houle T, Nash JM. Stress and headache chronification. Headache. 2008 Jan; 48(1):40-4. PMID: 18184284.
    View in: PubMed
  81. Nuttall GA, Houle TT. Liars, damn liars, and propensity scores. Anesthesiology. 2008 Jan; 108(1):3-4. PMID: 18156873.
    View in: PubMed
  82. Maizels M, Houle T. Results of screening with the brief headache screen compared with a modified IDMigraine. Headache. 2008 Mar; 48(3):385-94. PMID: 18028378.
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  83. Harden RN, Remble TA, Houle TT, Long JF, Markov MS, Gallizzi MA. Prospective, randomized, single-blind, sham treatment-controlled study of the safety and efficacy of an electromagnetic field device for the treatment of chronic low back pain: a pilot study. Pain Pract. 2007 Sep; 7(3):248-55. PMID: 17714104.
    View in: PubMed
  84. Houle TT. Statistical reporting for current and future readers. Anesthesiology. 2007 Aug; 107(2):193-4. PMID: 17667559.
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  85. Stribling WK, Slaughter TF, Houle TT, Sane DC. Beyond the platelet count: heparin antibodies as independent risk predictors. Am Heart J. 2007 Jun; 153(6):900-6. PMID: 17540189.
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  86. Smitherman TA, Huerkamp JK, Miller BI, Houle TT, O'Jile JR. The relation of depression and anxiety to measures of executive functioning in a mixed psychiatric sample. Arch Clin Neuropsychol. 2007 Jun; 22(5):647-54. PMID: 17521865.
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  87. Nicholson RA, Houle TT, Rhudy JL, Norton PJ. Psychological risk factors in headache. Headache. 2007 Mar; 47(3):413-26. PMID: 17371358; PMCID: PMC2408884.
  88. Houle TT. Importance of effect sizes for the accumulation of knowledge. Anesthesiology. 2007 Mar; 106(3):415-7. PMID: 17325496.
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  89. Harden RN, Revivo G, Song S, Nampiaparampil D, Golden G, Kirincic M, Houle TT. A critical analysis of the tender points in fibromyalgia. Pain Med. 2007 Mar; 8(2):147-56. PMID: 17305686.
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  90. Corcoran W, Butterworth J, Weller RS, Beck JC, Gerancher JC, Houle TT, Groban L. Local anesthetic-induced cardiac toxicity: a survey of contemporary practice strategies among academic anesthesiology departments. Anesth Analg. 2006 Nov; 103(5):1322-6. PMID: 17056977.
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  91. Houle TD, Ram ML, McMurray WJ, Cala SE. Different endoplasmic reticulum trafficking and processing pathways for calsequestrin (CSQ) and epitope-tagged CSQ. Exp Cell Res. 2006 Dec 10; 312(20):4150-61. PMID: 17045261.
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  92. Houle TT, Dhingra LK, Remble TA, Rokicki LA, Penzien DB. Not tonight, I have a headache? Headache. 2006 Jun; 46(6):983-90. PMID: 16732844.
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  93. Stanos S, Houle TT. Multidisciplinary and interdisciplinary management of chronic pain. Phys Med Rehabil Clin N Am. 2006 May; 17(2):435-50, vii. PMID: 16616276.
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  94. Pan PH, Coghill R, Houle TT, Seid MH, Lindel WM, Parker RL, Washburn SA, Harris L, Eisenach JC. Multifactorial preoperative predictors for postcesarean section pain and analgesic requirement. Anesthesiology. 2006 Mar; 104(3):417-25. PMID: 16508387.
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  95. Martin VT, Penzien DB, Houle TT, Andrew ME, Lofland KR. The predictive value of abbreviated migraine diagnostic criteria. Headache. 2005 Oct; 45(9):1102-12. PMID: 16178941.
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  96. Harden RN, Houle TT, Remble TA, Lin W, Wang K, Saltz S. Topiramate for phantom limb pain: a time-series analysis. Pain Med. 2005 Sep-Oct; 6(5):375-8. PMID: 16266358.
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  97. Harden RN, Weinland SR, Remble TA, Houle TT, Colio S, Steedman S, Kee WG. Medication Quantification Scale Version III: update in medication classes and revised detriment weights by survey of American Pain Society Physicians. J Pain. 2005 Jun; 6(6):364-71. PMID: 15943958.
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  98. Penzien DB, Andrasik F, Freidenberg BM, Houle TT, Lake AE, Lipchik GL, Holroyd KA, Lipton RB, McCrory DC, Nash JM, Nicholson RA, Powers SW, Rains JC, Wittrock DA. Guidelines for trials of behavioral treatments for recurrent headache, first edition: American Headache Society Behavioral Clinical Trials Workgroup. Headache. 2005 May; 45 Suppl 2:S110-32. PMID: 15921503.
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  99. Houle TT, Lauzon JJ. Comment: "the premonitory symptoms (prodrome): a tertiary care study of 893 migraineurs". Headache. 2005 May; 45(5):616-7. PMID: 15953288.
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  100. Houle TT, Penzien DB, Rains JC. Time-series features of headache: individual distributions, patterns, and predictability of pain. Headache. 2005 May; 45(5):445-58. PMID: 15953261.
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  101. Houle TT, Remble TA, Houle TA. The examination of headache activity using time-series research designs. Headache. 2005 May; 45(5):438-44. PMID: 15953260.
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  102. Houle TT, Penzien DB, Houle CK. Statistical power and sample size estimation for headache research: an overview and power calculation tools. Headache. 2005 May; 45(5):414-8. PMID: 15953257.
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  103. Harden RN, Houle TT, Green S, Remble TA, Weinland SR, Colio S, Lauzon J, Kuiken T. Biofeedback in the treatment of phantom limb pain: a time-series analysis. Appl Psychophysiol Biofeedback. 2005 Mar; 30(1):83-93. PMID: 15889588.
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  104. Dhaher YY, Tsoumanis AD, Houle TT, Rymer WZ. Neuromuscular reflexes contribute to knee stiffness during valgus loading. J Neurophysiol. 2005 May; 93(5):2698-709. PMID: 15615832.
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  105. Brander VA, Stulberg SD, Adams AD, Harden RN, Bruehl S, Stanos SP, Houle T. Predicting total knee replacement pain: a prospective, observational study. Clin Orthop Relat Res. 2003 Nov; (416):27-36. PMID: 14646737.
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  106. Rokicki LA, Houle TT, Dhingra LK, Weinland SR, Urban AM, Bhalla RK. A preliminary analysis of EMG variance as an index of change in EMG biofeedback treatment of tension-type headache. Appl Psychophysiol Biofeedback. 2003 Sep; 28(3):205-15. PMID: 12964452.
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  107. King AC, Houle T, de Wit H, Holdstock L, Schuster A. Biphasic alcohol response differs in heavy versus light drinkers. Alcohol Clin Exp Res. 2002 Jun; 26(6):827-35. PMID: 12068251.
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  108. Hsu C, Harden RN, Houle T. Nicotine and caffeine intake in complex regional pain syndrome. J Back Musculoskelet Rehabil. 2002 Jan 01; 16(1):33-8. PMID: 22387362.
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  109. Rokicki LA, Semenchuk EM, Bruehl S, Lofland KR, Houle TT. An examination of the validity of the IHS classification system for migraine and tension-type headache in the college student population. Headache. 1999 Nov-Dec; 39(10):720-7. PMID: 11279948.
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