Harvard Catalyst Profiles

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Hao Li, Ph.D.


Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Li H, Boulougoura A, Endo Y, Tsokos GC. Abnormalities of T cells in systemic lupus erythematosus: new insights in pathogenesis and therapeutic strategies. J Autoimmun. 2022 10; 132:102870. PMID: 35872102.
    Citations:    Fields:    
  2. Wu X, Liu Y, Jin S, Wang M, Jiao Y, Yang B, Lu X, Ji X, Fei Y, Yang H, Zhao L, Chen H, Zhang Y, Li H, Lipsky PE, Tsokos GC, Bai F, Zhang X. Single-cell sequencing of immune cells from anticitrullinated peptide antibody positive and negative rheumatoid arthritis. Nat Commun. 2021 08 17; 12(1):4977. PMID: 34404786.
    Citations: 9     Fields:    Translation:HumansCells
  3. Li P, Jiang M, Li K, Li H, Zhou Y, Xiao X, Xu Y, Krishfield S, Lipsky PE, Tsokos GC, Zhang X. Glutathione peroxidase 4-regulated neutrophil ferroptosis induces systemic autoimmunity. Nat Immunol. 2021 09; 22(9):1107-1117. PMID: 34385713; PMCID: PMC8609402.
    Citations: 22     Fields:    Translation:HumansAnimalsCells
  4. Li H, Tsokos MG, Bhargava R, Adamopoulos IE, Menn-Josephy H, Stillman IE, Rosenstiel P, Jordan J, Tsokos GC. IL-23 reshapes kidney resident cell metabolism and promotes local kidney inflammation. J Clin Invest. 2021 06 15; 131(12). PMID: 33956666; PMCID: PMC8203450.
    Citations: 6     Fields:    Translation:HumansAnimalsCells
  5. Li H, Tsokos GC. Double-negative T cells in autoimmune diseases. Curr Opin Rheumatol. 2021 03 01; 33(2):163-172. PMID: 33394752; PMCID: PMC8018563.
    Citations: 6     Fields:    Translation:HumansCells
  6. Katsuyama T, Li H, Krishfield SM, Kyttaris VC, Moulton VR. Splicing factor SRSF1 limits IFN-? production via RhoH and ameliorates experimental nephritis. Rheumatology (Oxford). 2021 01 05; 60(1):420-429. PMID: 32810232; PMCID: PMC7785303.
    Citations: 4     Fields:    Translation:HumansAnimalsCells
  7. Chen BD, Jia XM, Xu JY, Zhao LD, Ji JY, Wu BX, Ma Y, Li H, Zuo XX, Pan WY, Wang XH, Ye S, Tsokos GC, Wang J, Zhang X. An Autoimmunogenic and Proinflammatory Profile Defined by the Gut Microbiota of Patients With Untreated Systemic Lupus Erythematosus. Arthritis Rheumatol. 2021 02; 73(2):232-243. PMID: 33124780.
    Citations: 22     Fields:    Translation:HumansAnimalsCells
  8. Xiao X, Da G, Xie X, Liu X, Zhang L, Zhou B, Li H, Li P, Yang H, Chen H, Fei Y, Tsokos GC, Zhao L, Zhang X. Tuberculosis in patients with systemic lupus erythematosus-a 37-year longitudinal survey-based study. J Intern Med. 2021 07; 290(1):101-115. PMID: 33259665.
    Citations: 2     Fields:    Translation:Humans
  9. Li H, Tsokos GC. IL-23/IL-17 Axis in Inflammatory Rheumatic Diseases. Clin Rev Allergy Immunol. 2021 Feb; 60(1):31-45. PMID: 33185790.
    Citations: 1     Fields:    Translation:HumansAnimalsCells
  10. Hong H, Gao M, Wu Q, Yang P, Liu S, Li H, Burrows PD, Cua D, Chen JY, Hsu HC, Mountz JD. IL-23 Promotes a Coordinated B Cell Germinal Center Program for Class-Switch Recombination to IgG2b in BXD2 Mice. J Immunol. 2020 07 15; 205(2):346-358. PMID: 32554431; PMCID: PMC7374065.
    Citations: 1     Fields:    Translation:AnimalsCells
  11. Li H, Adamopoulos IE, Moulton VR, Stillman IE, Herbert Z, Moon JJ, Sharabi A, Krishfield S, Tsokos MG, Tsokos GC. Systemic lupus erythematosus favors the generation of IL-17 producing double negative T cells. Nat Commun. 2020 06 05; 11(1):2859. PMID: 32503973.
    Citations: 25     Fields:    Translation:HumansAnimalsCells
  12. Zhang X, Chen BD, Zhao LD, Li H. The Gut Microbiota: Emerging Evidence in Autoimmune Diseases. Trends Mol Med. 2020 09; 26(9):862-873. PMID: 32402849.
    Citations: 39     Fields:    Translation:HumansAnimals
  13. Meidan E, Li H, Pan W, Kono M, Yu S, Kyttaris VC, Ioannidis C, Rodriguez Rodriguez N, Crispin JC, Apostolidis SA, Lee P, Manis J, Sharabi A, Tsokos MG, Tsokos GC. Serine/threonine phosphatase PP2A is essential for optimal B cell function. JCI Insight. 2020 03 12; 5(5). PMID: 32161189.
    Citations: 1     Fields:    Translation:HumansAnimalsCells
  14. Katsuyama T, Li H, Comte D, Tsokos GC, Moulton VR. Splicing factor SRSF1 controls T cell hyperactivity and systemic autoimmunity. J Clin Invest. 2019 12 02; 129(12):5411-5423. PMID: 31487268; PMCID: PMC6877308.
    Citations: 24     Fields:    Translation:HumansAnimalsCells
  15. Sharabi A, Li H, Kasper IR, Pan W, Meidan E, Tsokos MG, Moulton VR, Tsokos GC. PP2A enables IL-2 signaling by preserving IL-2Rß chain expression during Treg development. JCI Insight. 2019 03 26; 5. PMID: 30912768.
    Citations: 3     Fields:    Translation:AnimalsCells
  16. Li H, Tsokos MG, Bickerton S, Sharabi A, Li Y, Moulton VR, Kong P, Fahmy TM, Tsokos GC. Precision DNA demethylation ameliorates disease in lupus-prone mice. JCI Insight. 2018 08 23; 3(16). PMID: 30135300; PMCID: PMC6141184.
    Citations: 20     Fields:    Translation:HumansAnimalsCells
  17. Lowe RM, Li H, Hsu HC, Mountz JD. Regulation of Negative Selection in the Thymus by Cytokines: Novel Role of IL-23 to Regulate ROR?t. Signaling Mechanisms Regulating T Cell Diversity and Function. 2018. View Publication.
  18. Moulton VR, Suarez-Fueyo A, Meidan E, Li H, Mizui M, Tsokos GC. Pathogenesis of Human Systemic Lupus Erythematosus: A Cellular Perspective. Trends Mol Med. 2017 07; 23(7):615-635. PMID: 28623084.
    Citations: 109     Fields:    Translation:HumansAnimalsCells
  19. Zhang M, Bracaglia C, Prencipe G, Bemrich-Stolz CJ, Beukelman T, Dimmitt RA, Chatham WW, Zhang K, Li H, Walter MR, De Benedetti F, Grom AA, Cron RQ. A Heterozygous RAB27A Mutation Associated with Delayed Cytolytic Granule Polarization and Hemophagocytic Lymphohistiocytosis. J Immunol. 2016 Mar 15; 196(6):2492-503. PMID: 26880764; PMCID: PMC4779709.
    Citations: 24     Fields:    Translation:HumansCells
  20. Li H, Fu YX, Wu Q, Zhou Y, Crossman DK, Yang P, Li J, Luo B, Morel LM, Kabarowski JH, Yagita H, Ware CF, Hsu HC, Mountz JD. Interferon-induced mechanosensing defects impede apoptotic cell clearance in lupus. J Clin Invest. 2015 Jul 01; 125(7):2877-90. PMID: 26098211; PMCID: PMC4563689.
    Citations: 27     Fields:    Translation:HumansAnimalsCells
  21. Hamilton JA, Li J, Wu Q, Yang P, Luo B, Li H, Bradley JE, Taylor JJ, Randall TD, Mountz JD, Hsu HC. General Approach for Tetramer-Based Identification of Autoantigen-Reactive B Cells: Characterization of La- and snRNP-Reactive B Cells in Autoimmune BXD2 Mice. J Immunol. 2015 May 15; 194(10):5022-34. PMID: 25888644; PMCID: PMC4417409.
    Citations: 16     Fields:    Translation:HumansAnimalsCells
  22. Li J, Hsu HC, Ding Y, Li H, Wu Q, Yang P, Luo B, Rowse AL, Spalding DM, Bridges SL, Mountz JD. Inhibition of fucosylation reshapes inflammatory macrophages and suppresses type II collagen-induced arthritis. Arthritis Rheumatol. 2014 Sep; 66(9):2368-79. PMID: 24838610; PMCID: PMC4146698.
    Citations: 24     Fields:    Translation:HumansAnimalsCells
  23. Sang A, Zheng YY, Yin Y, Dozmorov I, Li H, Hsu HC, Mountz JD, Morel L. Dysregulated cytokine production by dendritic cells modulates B cell responses in the NZM2410 mouse model of lupus. PLoS One. 2014; 9(8):e102151. PMID: 25093822.
    Citations: 23     Fields:    Translation:HumansAnimalsCells
  24. Li H, Hsu HC, Wu Q, Yang P, Li J, Luo B, Oukka M, Steele CH, Cua DJ, Grizzle WE, Mountz JD. IL-23 promotes TCR-mediated negative selection of thymocytes through the upregulation of IL-23 receptor and ROR?t. Nat Commun. 2014 Jul 08; 5:4259. PMID: 25001511.
    Citations: 7     Fields:    Translation:AnimalsCells
  25. McGuire DJ, Rowse AL, Li H, Peng BJ, Sestero CM, Cashman KS, De Sarno P, Raman C. CD5 enhances Th17-cell differentiation by regulating IFN-? response and ROR?t localization. Eur J Immunol. 2014 Apr; 44(4):1137-42. PMID: 24356888.
    Citations: 11     Fields:    Translation:AnimalsCells
  26. Li J, Yang P, Wu Q, Li H, Ding Y, Hsu HC, Spalding DM, Mountz JD. Death receptor 5-targeted depletion of interleukin-23-producing macrophages, Th17, and Th1/17 associated with defective tyrosine phosphatase in mice and patients with rheumatoid arthritis. Arthritis Rheum. 2013 Oct; 65(10):2594-605. PMID: 23818173; PMCID: PMC3993980.
    Citations: 10     Fields:    Translation:HumansAnimalsCells
  27. Li H, Wu Q, Li J, Yang P, Zhu Z, Luo B, Hsu HC, Mountz JD. Cutting Edge: defective follicular exclusion of apoptotic antigens due to marginal zone macrophage defects in autoimmune BXD2 mice. J Immunol. 2013 May 01; 190(9):4465-9. PMID: 23543760; PMCID: PMC3656168.
    Citations: 15     Fields:    Translation:AnimalsCells
  28. Zhu Z, Li R, Li H, Zhou T, Davis RS. FCRL5 exerts binary and compartment-specific influence on innate-like B-cell receptor signaling. Proc Natl Acad Sci U S A. 2013 Apr 02; 110(14):E1282-90. PMID: 23509253.
    Citations: 17     Fields:    Translation:AnimalsCells
  29. Li J, Hsu HC, Yang P, Wu Q, Li H, Edgington LE, Bogyo M, Kimberly RP, Mountz JD. Treatment of arthritis by macrophage depletion and immunomodulation: testing an apoptosis-mediated therapy in a humanized death receptor mouse model. Arthritis Rheum. 2012 Apr; 64(4):1098-109. PMID: 22006294; PMCID: PMC3596268.
    Citations: 35     Fields:    Translation:HumansAnimalsCells
  30. Wang JH, Wu Q, Yang P, Li H, Li J, Mountz JD, Hsu HC. Type I interferon-dependent CD86(high) marginal zone precursor B cells are potent T cell costimulators in mice. Arthritis Rheum. 2011 Apr; 63(4):1054-64. PMID: 21225691; PMCID: PMC3310977.
    Citations: 18     Fields:    Translation:AnimalsCells
  31. Li H, Wang LY, Xu GY, Chen Y, Jiang R, Li Y. Cloning, expression and characterization of the Ste6 gene encoding a UDP-glucose dehydrogenase in Streptomyces. Yi Chuan Xue Bao. 2005 Nov; 32(11):1213-20. PMID: 16318288.
    Citations:    Fields:    Translation:Cells
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.