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Neil T Umbreit, Ph.D.

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Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Gutierrez A, Kim JO, Umbreit NT, Asbury CL, Davis TN, Miller MP, Biggins S. Cdk1 Phosphorylation of the Dam1 Complex Strengthens Kinetochore-Microtubule Attachments. Curr Biol. 2020 Sep 08. PMID: 32946748.
    Citations:    
  2. McBride MJ, Mashtalir N, Winter EB, Dao HT, Filipovski M, D'Avino AR, Seo HS, Umbreit NT, St Pierre R, Valencia AM, Qian K, Zullow HJ, Jaffe JD, Dhe-Paganon S, Muir TW, Kadoch C. The nucleosome acidic patch and H2A ubiquitination underlie mSWI/SNF recruitment in synovial sarcoma. Nat Struct Mol Biol. 2020 Sep; 27(9):836-845. PMID: 32747783.
    Citations:    
  3. Umbreit NT, Zhang CZ, Lynch LD, Blaine LJ, Cheng AM, Tourdot R, Sun L, Almubarak HF, Judge K, Mitchell TJ, Spektor A, Pellman D. Mechanisms generating cancer genome complexity from a single cell division error. Science. 2020 04 17; 368(6488). PMID: 32299917.
    Citations:    
  4. Jiao AL, Perales R, Umbreit NT, Haswell JR, Piper ME, Adams BD, Pellman D, Kennedy S, Slack FJ. Human nuclear RNAi-defective 2 (NRDE2) is an essential RNA splicing factor. RNA. 2019 03; 25(3):352-363. PMID: 30538148.
    Citations:    Fields:    
  5. Spektor A, Umbreit NT, Pellman D. Cell Biology: When Your Own Chromosomes Act like Foreign DNA. Curr Biol. 2017 11 20; 27(22):R1228-R1231. PMID: 29161564.
    Citations:    Fields:    
  6. Umbreit NT, Pellman D. Cancer biology: Genome jail-break triggers lockdown. Nature. 2017 10 19; 550(7676):340-341. PMID: 28976957.
    Citations:    Fields:    Translation:Humans
  7. Viswanath S, Bonomi M, Kim SJ, Klenchin VA, Taylor KC, Yabut KC, Umbreit NT, Van Epps HA, Meehl J, Jones MH, Russel D, Velazquez-Muriel JA, Winey M, Rayment I, Davis TN, Sali A, Muller EG. The molecular architecture of the yeast spindle pole body core determined by Bayesian integrative modeling. Mol Biol Cell. 2017 Nov 07; 28(23):3298-3314. PMID: 28814505.
    Citations: 5     Fields:    Translation:AnimalsCells
  8. Kim JO, Zelter A, Umbreit NT, Bollozos A, Riffle M, Johnson R, MacCoss MJ, Asbury CL, Davis TN. The Ndc80 complex bridges two Dam1 complex rings. Elife. 2017 02 13; 6. PMID: 28191870.
    Citations: 7     Fields:    Translation:AnimalsCells
  9. Zelter A, Bonomi M, Kim JO, Umbreit NT, Hoopmann MR, Johnson R, Riffle M, Jaschob D, MacCoss MJ, Moritz RL, Davis TN. The molecular architecture of the Dam1 kinetochore complex is defined by cross-linking based structural modelling. Nat Commun. 2015 Nov 12; 6:8673. PMID: 26560693.
    Citations: 11     Fields:    Translation:HumansAnimalsCells
  10. Kudalkar EM, Scarborough EA, Umbreit NT, Zelter A, Gestaut DR, Riffle M, Johnson RS, MacCoss MJ, Asbury CL, Davis TN. Regulation of outer kinetochore Ndc80 complex-based microtubule attachments by the central kinetochore Mis12/MIND complex. Proc Natl Acad Sci U S A. 2015 Oct 13; 112(41):E5583-9. PMID: 26430240.
    Citations: 10     Fields:    Translation:AnimalsCells
  11. Umbreit NT, Miller MP, Tien JF, Ortol√° JC, Gui L, Lee KK, Biggins S, Asbury CL, Davis TN. Kinetochores require oligomerization of Dam1 complex to maintain microtubule attachments against tension and promote biorientation. Nat Commun. 2014 Sep 19; 5:4951. PMID: 25236177.
    Citations: 15     Fields:    Translation:AnimalsCells
  12. Tien JF, Umbreit NT, Zelter A, Riffle M, Hoopmann MR, Johnson RS, Fonslow BR, Yates JR, MacCoss MJ, Moritz RL, Asbury CL, Davis TN. Kinetochore biorientation in Saccharomyces cerevisiae requires a tightly folded conformation of the Ndc80 complex. Genetics. 2014 Dec; 198(4):1483-93. PMID: 25230952.
    Citations: 7     Fields:    Translation:AnimalsCells
  13. Tien JF, Fong KK, Umbreit NT, Payen C, Zelter A, Asbury CL, Dunham MJ, Davis TN. Coupling unbiased mutagenesis to high-throughput DNA sequencing uncovers functional domains in the Ndc80 kinetochore protein of Saccharomyces cerevisiae. Genetics. 2013 Sep; 195(1):159-70. PMID: 23833183.
    Citations: 10     Fields:    Translation:AnimalsCells
  14. Umbreit NT, Gestaut DR, Tien JF, Vollmar BS, Gonen T, Asbury CL, Davis TN. The Ndc80 kinetochore complex directly modulates microtubule dynamics. Proc Natl Acad Sci U S A. 2012 Oct 02; 109(40):16113-8. PMID: 22908300.
    Citations: 41     Fields:    Translation:HumansCells
  15. Umbreit NT, Davis TN. Mitosis puts sisters in a strained relationship: force generation at the kinetochore. Exp Cell Res. 2012 Jul 15; 318(12):1361-6. PMID: 22564894.
    Citations: 4     Fields:    Translation:HumansAnimalsCells
  16. Tien JF, Umbreit NT, Gestaut DR, Franck AD, Cooper J, Wordeman L, Gonen T, Asbury CL, Davis TN. Cooperation of the Dam1 and Ndc80 kinetochore complexes enhances microtubule coupling and is regulated by aurora B. J Cell Biol. 2010 May 17; 189(4):713-23. PMID: 20479468.
    Citations: 91     Fields:    Translation:AnimalsCells
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.