Harvard Catalyst Profiles

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Nikki Kong, Ph.D.


Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Cruite JT, Dann GP, Che J, Donovan KA, Ferrao S, Ficarro SB, Fischer ES, Gray NS, Huerta F, Kong NR, Liu H, Marto JA, Metivier RJ, Nowak RP, Zerfas BL, Jones LH. Cereblon covalent modulation through structure-based design of histidine targeting chemical probes. RSC Chem Biol. 2022 Aug 31; 3(9):1105-1110. PMID: 36128501; PMCID: PMC9428674.
    Citations: 4     
  2. Kong NR, Liu H, Che J, Jones LH. Physicochemistry of Cereblon Modulating Drugs Determines Pharmacokinetics and Disposition. ACS Med Chem Lett. 2021 Nov 11; 12(11):1861-1865. PMID: 34795877; PMCID: PMC8591734.
  3. Yang J, Gao C, Liu M, Liu YC, Kwon J, Qi J, Tian X, Stein A, Liu YV, Kong NR, Wu Y, Yin S, Xi J, Chen Z, Kumari K, Wong H, Luo H, Silberstein LE, Thoms JAI, Unnikrishnan A, Pimanda JE, Tenen DG, Chai L. Targeting an Inducible SALL4-Mediated Cancer Vulnerability with Sequential Therapy. Cancer Res. 2021 12 01; 81(23):6018-6028. PMID: 34593523; PMCID: PMC8639708.
    Citations:    Fields:    Translation:HumansAnimalsCells
  4. Kong NR, Chai L, Tenen DG, Bassal MA. A modified CUT&RUN protocol and analysis pipeline to identify transcription factor binding sites in human cell lines. STAR Protoc. 2021 09 17; 2(3):100750. PMID: 34458869; PMCID: PMC8379522.
    Citations:    Fields:    Translation:HumansCells
  5. Lee JD, Paulo JA, Posey RR, Mugoni V, Kong NR, Cheloni G, Lee YR, Slack FJ, Tenen DG, Clohessy JG, Gygi SP, Pandolfi PP. Dual DNA and protein tagging of open chromatin unveils dynamics of epigenomic landscapes in leukemia. Nat Methods. 2021 03; 18(3):293-302. PMID: 33649590; PMCID: PMC8272231.
    Citations:    Fields:    Translation:HumansCells
  6. Kong NR, Bassal MA, Tan HK, Kurland JV, Yong KJ, Young JJ, Yang Y, Li F, Lee JD, Liu Y, Wu CS, Stein A, Luo HR, Silberstein LE, Bulyk ML, Tenen DG, Chai L. Zinc Finger Protein SALL4 Functions through an AT-Rich Motif to Regulate Gene Expression. Cell Rep. 2021 01 05; 34(1):108574. PMID: 33406418.
    Citations: 7     Fields:    Translation:HumansCells
  7. Tan JL, Li F, Yeo JZ, Yong KJ, Bassal MA, Ng GH, Lee MY, Leong CY, Tan HK, Wu CS, Liu BH, Chan TH, Tan ZH, Chan YS, Wang S, Lim ZH, Toh TB, Hooi L, Low KN, Ma S, Kong NR, Stein AJ, Wu Y, Thangavelu MT, Suzuki A, Periyasamy G, Asara JM, Dan YY, Bonney GK, Chow EK, Lu GD, Ng HH, Kanagasundaram Y, Ng SB, Tam WL, Tenen DG, Chai L. New High-Throughput Screening Identifies Compounds That Reduce Viability Specifically in Liver Cancer Cells That Express High Levels of SALL4 by Inhibiting Oxidative Phosphorylation. Gastroenterology. 2019 12; 157(6):1615-1629.e17. PMID: 31446059; PMCID: PMC7309153.
    Citations: 14     Fields:    Translation:HumansAnimalsCells
  8. Kong NR, Davis M, Chai L, Winoto A, Tjian R. MEF2C and EBF1 Co-regulate B Cell-Specific Transcription. PLoS Genet. 2016 Feb; 12(2):e1005845. PMID: 26900922; PMCID: PMC4762780.
    Citations: 14     Fields:    Translation:HumansCells
  9. Tatetsu H, Kong NR, Chong G, Amabile G, Tenen DG, Chai L. SALL4, the missing link between stem cells, development and cancer. Gene. 2016 Jun 15; 584(2):111-9. PMID: 26892498.
    Citations: 34     Fields:    Translation:HumansCells
  10. Young JJ, Kjolby RA, Kong NR, Monica SD, Harland RM. Spalt-like 4 promotes posterior neural fates via repression of pou5f3 family members in Xenopus. Development. 2014 Apr; 141(8):1683-93. PMID: 24715458.
    Citations: 16     Fields:    Translation:AnimalsCells
  11. Wang F, Zhao W, Kong N, Cui W, Chai L. The next new target in leukemia: The embryonic stem cell gene SALL4. Mol Cell Oncol. 2014; 1(4):e969169. PMID: 25977939; PMCID: PMC4428154.
    Citations: 9     
  12. Gao C, Kong NR, Li A, Tatetu H, Ueno S, Yang Y, He J, Yang J, Ma Y, Kao GS, Tenen DG, Chai L. SALL4 is a key transcription regulator in normal human hematopoiesis. Transfusion. 2013 May; 53(5):1037-49. PMID: 22934838.
    Citations: 27     Fields:    Translation:HumansAnimalsCells
  13. Gao C, Kong NR, Chai L. The role of stem cell factor SALL4 in leukemogenesis. Crit Rev Oncog. 2011; 16(1-2):117-27. PMID: 22150312.
    Citations: 17     Fields:    Translation:HumansAnimals
  14. Lu J, Jeong HW, Jeong H, Kong N, Yang Y, Carroll J, Luo HR, Silberstein LE, Chai L. Stem cell factor SALL4 represses the transcriptions of PTEN and SALL1 through an epigenetic repressor complex. PLoS One. 2009; 4(5):e5577. PMID: 19440552.
    Citations: 80     Fields:    Translation:HumansAnimalsCells
  15. Cui W, Kong NR, Ma Y, Amin HM, Lai R, Chai L. Differential expression of the novel oncogene, SALL4, in lymphoma, plasma cell myeloma, and acute lymphoblastic leukemia. Mod Pathol. 2006 Dec; 19(12):1585-92. PMID: 16998462.
    Citations: 34     Fields:    Translation:HumansCells
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.