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profileJohn S Albin, M.D., Ph.D.

TitleResearch Fellow in Medicine (EXT)
InstitutionMassachusetts General Hospital
DepartmentMedicine
AddressMassachusetts General Hospital
Infectious Disease Unit GRJ-504
55 Fruit St
Boston MA 02114
Phone617/643-3856
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The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
F30DA026310     (ALBIN, JOHN SQUIRE)May 25, 2009 - May 24, 2013
NIH/NIDA
Determining the Role of APOBEC3 Proteins in HIV-1 Drug Resistance
Role: Principal Investigator

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Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Richards C, Albin JS, Demir Ö, Shaban NM, Luengas EM, Land AM, Anderson BD, Holten JR, Anderson JS, Harki DA, Amaro RE, Harris RS. The Binding Interface between Human APOBEC3F and HIV-1 Vif Elucidated by Genetic and Computational Approaches. Cell Rep. 2015 Dec 01; 13(9):1781-8. PMID: 26628363; PMCID: PMC4684092.
  2. Land AM, Shaban NM, Evans L, Hultquist JF, Albin JS, Harris RS. APOBEC3F determinants of HIV-1 Vif sensitivity. J Virol. 2014 Nov; 88(21):12923-7. PMID: 25142588; PMCID: PMC4248952.
  3. Albin JS, Brown WL, Harris RS. Catalytic activity of APOBEC3F is required for efficient restriction of Vif-deficient human immunodeficiency virus. Virology. 2014 Feb; 450-451:49-54. PMID: 24503066; PMCID: PMC3932626.
  4. Bohn MF, Shandilya SM, Albin JS, Kouno T, Anderson BD, McDougle RM, Carpenter MA, Rathore A, Evans L, Davis AN, Zhang J, Lu Y, Somasundaran M, Matsuo H, Harris RS, Schiffer CA. Crystal structure of the DNA cytosine deaminase APOBEC3F: the catalytically active and HIV-1 Vif-binding domain. Structure. 2013 Jun 04; 21(6):1042-50. PMID: 23685212; PMCID: PMC3805256.
  5. Albin JS, Anderson JS, Johnson JR, Harjes E, Matsuo H, Krogan NJ, Harris RS. Dispersed sites of HIV Vif-dependent polyubiquitination in the DNA deaminase APOBEC3F. J Mol Biol. 2013 Apr 12; 425(7):1172-82. PMID: 23318957; PMCID: PMC3602375.
  6. Albin JS, Harris RS. Human Immunodeficiency Virus Reverse Transcriptase: A Bench-to-Bedside Success, Eds. Stuart LeGrice and Matthias Gotte. APOBECs and Their Role in Proviral DNA Synthesis. 2013; 253-280.
  7. Albin JS, LaRue RS, Weaver JA, Brown WL, Shindo K, Harjes E, Matsuo H, Harris RS. A single amino acid in human APOBEC3F alters susceptibility to HIV-1 Vif. J Biol Chem. 2010 Dec 24; 285(52):40785-92. PMID: 20971849; PMCID: PMC3003379.
  8. Albin JS, Haché G, Hultquist JF, Brown WL, Harris RS. Long-term restriction by APOBEC3F selects human immunodeficiency virus type 1 variants with restored Vif function. J Virol. 2010 Oct; 84(19):10209-19. PMID: 20686027; PMCID: PMC2937771.
  9. Refsland EW, Stenglein MD, Shindo K, Albin JS, Brown WL, Harris RS. Quantitative profiling of the full APOBEC3 mRNA repertoire in lymphocytes and tissues: implications for HIV-1 restriction. Nucleic Acids Res. 2010 Jul; 38(13):4274-84. PMID: 20308164; PMCID: PMC2910054.
  10. Albin JS, Harris RS. Interactions of host APOBEC3 restriction factors with HIV-1 in vivo: implications for therapeutics. Expert Rev Mol Med. 2010 Jan 22; 12:e4. PMID: 20096141; PMCID: PMC2860793.
  11. Haché G, Shindo K, Albin JS, Harris RS. Evolution of HIV-1 isolates that use a novel Vif-independent mechanism to resist restriction by human APOBEC3G. Curr Biol. 2008 Jun 03; 18(11):819-24. PMID: 18501607; PMCID: PMC2491687.
  12. Sundaram P, Han W, Cohen N, Echalier B, Albin J, Timmons L. Caenorhabditis elegans ABCRNAi transporters interact genetically with rde-2 and mut-7. Genetics. 2008 Feb; 178(2):801-14. PMID: 18245353; PMCID: PMC2248369.
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