Yuan Xiong | Harvard Catalyst Profiles

Yuan Xiong, Ph.D.

Title

Research Associate in Biological Chemistry and Molecular Pharmacology

Institution

Dana-Farber Cancer Institute

Department

BCMP

Address

Dry Dock 0431
27 Dry Dock Ave
Boston MA 02210

selected publications|

Bibliographic

selected publications

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.

Qian D, Zhou H, Fan P, Yu T, Patel A, O'Brien M, Wang Z, Lu S, Tong G, Shan Y, Wang L, Gao Y, Xiong Y, Zhang L, Wang X, Liu Y, Zhou S. A Traditional Chinese Medicine Plant Extract Prevents Alcohol-Induced Osteopenia. Front Pharmacol. 2021; 12:754088. PMID: 35002697; PMCID: PMC8730326.

Citations:
Xiong Y, Donovan KA, Eleuteri NA, Kirmani N, Yue H, Razov A, Krupnick NM, Nowak RP, Fischer ES. Chemo-proteomics exploration of HDAC degradability by small molecule degraders. Cell Chem Biol. 2021 10 21; 28(10):1514-1527.e4. PMID: 34314730.

Citations: 4 Fields:
Bio Biochemistry Bio Biology Che Chemistry
Translation:Humans Cells
Nowak RP, Xiong Y, Kirmani N, Kalabathula J, Donovan KA, Eleuteri NA, Yuan JC, Fischer ES. Structure-Guided Design of a "Bump-and-Hole" Bromodomain-Based Degradation Tag. J Med Chem. 2021 08 12; 64(15):11637-11650. PMID: 34279939.

Citations: 3 Fields:
Che Chemistry
Translation:Humans Cells
Wu T, Yoon H, Xiong Y, Dixon-Clarke SE, Nowak RP, Fischer ES. Targeted protein degradation as a powerful research tool in basic biology and drug target discovery. Nat Struct Mol Biol. 2020 07; 27(7):605-614. PMID: 32541897.

Citations: 42 Fields:
Mol Molecular Biology
Translation:Humans Cells
Zeng M, Xiong Y, Safaee N, Nowak RP, Donovan KA, Yuan CJ, Nabet B, Gero TW, Feru F, Li L, Gondi S, Ombelets LJ, Quan C, Jänne PA, Kostic M, Scott DA, Westover KD, Fischer ES, Gray NS. Exploring Targeted Degradation Strategy for Oncogenic KRASG12C. Cell Chem Biol. 2020 01 16; 27(1):19-31.e6. PMID: 31883964.

Citations: 65 Fields:
Bio Biochemistry Bio Biology Che Chemistry
Translation:Humans Cells
Zeng M, Lu J, Li L, Feru F, Quan C, Gero TW, Ficarro SB, Xiong Y, Ambrogio C, Paranal RM, Catalano M, Shao J, Wong KK, Marto JA, Fischer ES, Jänne PA, Scott DA, Westover KD, Gray NS. Potent and Selective Covalent Quinazoline Inhibitors of KRAS G12C. Cell Chem Biol. 2017 Aug 17; 24(8):1005-1016.e3. PMID: 28781124.

Citations: 50 Fields:
Bio Biochemistry Bio Biology Che Chemistry
Translation:Humans Cells
Xiong Y, Lu J, Hunter J, Li L, Scott D, Choi HG, Lim SM, Manandhar A, Gondi S, Sim T, Westover KD, Gray NS. Covalent Guanosine Mimetic Inhibitors of G12C KRAS. ACS Med Chem Lett. 2017 Jan 12; 8(1):61-66. PMID: 28105276; PMCID: PMC5238463.

Citations: 28
Qi C, Xiong Y, Eschenbrenner-Lux V, Cong H, Porco JA. Asymmetric Syntheses of the Flavonoid Diels-Alder Natural Products Sanggenons C and O. J Am Chem Soc. 2016 Jan 27; 138(3):798-801. PMID: 26735066; PMCID: PMC4863937.

Citations: 5 Fields:
Che Chemistry
Translation:Cells
Xiong Y, Schaus SE, Porco JA. Metal-catalyzed cascade rearrangements of 3-alkynyl flavone ethers. Org Lett. 2013 Apr 19; 15(8):1962-5. PMID: 23574045.

Citations: 2 Fields:
Bio Biochemistry
Translation:Cells
Marié JC, Xiong Y, Min GK, Yeager AR, Taniguchi T, Berova N, Schaus SE, Porco JA. Enantioselective synthesis of 3,4-chromanediones via asymmetric rearrangement of 3-allyloxyflavones. J Org Chem. 2010 Jul 02; 75(13):4584-90. PMID: 20527786.

Citations: 9 Fields:
Che Chemistry
Translation:Cells

Year	Publications
2010	1
2013	1
2016	2
2017	1
2019	1
2020	1
2021	3

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