Harvard Catalyst Profiles

Contact, publication, and social network information about Harvard faculty and fellows.

Christopher D.M. Fletcher, M.D., M.B.,B.S.

Co-Author

This page shows the publications co-authored by Christopher Fletcher and Jason Hornick.
Connection Strength

12.307
  1. Hornick JL, Fletcher CD. Pseudomyogenic hemangioendothelioma: a distinctive, often multicentric tumor with indolent behavior. Am J Surg Pathol. 2011 Feb; 35(2):190-201.
    View in: PubMed
    Score: 0.521
  2. Hornick JL, Bundock EA, Fletcher CD. Hybrid schwannoma/perineurioma: clinicopathologic analysis of 42 distinctive benign nerve sheath tumors. Am J Surg Pathol. 2009 Oct; 33(10):1554-61.
    View in: PubMed
    Score: 0.475
  3. Hornick JL, Dal Cin P, Fletcher CD. Loss of INI1 expression is characteristic of both conventional and proximal-type epithelioid sarcoma. Am J Surg Pathol. 2009 Apr; 33(4):542-50.
    View in: PubMed
    Score: 0.459
  4. Hornick JL, Fletcher CD. Sclerosing PEComa: clinicopathologic analysis of a distinctive variant with a predilection for the retroperitoneum. Am J Surg Pathol. 2008 Apr; 32(4):493-501.
    View in: PubMed
    Score: 0.428
  5. Hornick JL, Fletcher CD. The role of KIT in the management of patients with gastrointestinal stromal tumors. Hum Pathol. 2007 May; 38(5):679-87.
    View in: PubMed
    Score: 0.402
  6. Hornick JL, Fletcher CD. Cellular neurothekeoma: detailed characterization in a series of 133 cases. Am J Surg Pathol. 2007 Mar; 31(3):329-40.
    View in: PubMed
    Score: 0.397
  7. Hornick JL, Fletcher CD. Intraarticular nodular fasciitis--a rare lesion: clinicopathologic analysis of a series. Am J Surg Pathol. 2006 Feb; 30(2):237-41.
    View in: PubMed
    Score: 0.368
  8. Hornick JL, Fletcher CD. PEComa: what do we know so far? Histopathology. 2006 Jan; 48(1):75-82.
    View in: PubMed
    Score: 0.366
  9. Hornick JL, Fletcher CD. Soft tissue perineurioma: clinicopathologic analysis of 81 cases including those with atypical histologic features. Am J Surg Pathol. 2005 Jul; 29(7):845-58.
    View in: PubMed
    Score: 0.354
  10. Hornick JL, Fletcher CD. Intestinal perineuriomas: clinicopathologic definition of a new anatomic subset in a series of 10 cases. Am J Surg Pathol. 2005 Jul; 29(7):859-65.
    View in: PubMed
    Score: 0.354
  11. Hornick JL, Fletcher CD. Intraabdominal cystic lymphangiomas obscured by marked superimposed reactive changes: clinicopathological analysis of a series. Hum Pathol. 2005 Apr; 36(4):426-32.
    View in: PubMed
    Score: 0.348
  12. Hornick JL, Bosenberg MW, Mentzel T, McMenamin ME, Oliveira AM, Fletcher CD. Pleomorphic liposarcoma: clinicopathologic analysis of 57 cases. Am J Surg Pathol. 2004 Oct; 28(10):1257-67.
    View in: PubMed
    Score: 0.336
  13. Hornick JL, Jaffe ES, Fletcher CD. Extranodal histiocytic sarcoma: clinicopathologic analysis of 14 cases of a rare epithelioid malignancy. Am J Surg Pathol. 2004 Sep; 28(9):1133-44.
    View in: PubMed
    Score: 0.334
  14. Hornick JL, Fletcher CD. The significance of KIT (CD117) in gastrointestinal stromal tumors. Int J Surg Pathol. 2004 Apr; 12(2):93-7.
    View in: PubMed
    Score: 0.324
  15. Hornick JL, Fletcher CD. Cutaneous myoepithelioma: a clinicopathologic and immunohistochemical study of 14 cases. Hum Pathol. 2004 Jan; 35(1):14-24.
    View in: PubMed
    Score: 0.319
  16. Hornick JL, Fletcher CD. Myoepithelial tumors of soft tissue: a clinicopathologic and immunohistochemical study of 101 cases with evaluation of prognostic parameters. Am J Surg Pathol. 2003 Sep; 27(9):1183-96.
    View in: PubMed
    Score: 0.312
  17. Hornick JL, Fletcher CD. Validating immunohistochemical staining for KIT (CD117). Am J Clin Pathol. 2003 Mar; 119(3):325-7.
    View in: PubMed
    Score: 0.301
  18. Hornick JL, Fletcher CD. Criteria for malignancy in nonvisceral smooth muscle tumors. Ann Diagn Pathol. 2003 Feb; 7(1):60-6.
    View in: PubMed
    Score: 0.299
  19. Hornick JL, Fletcher CD. Immunohistochemical staining for KIT (CD117) in soft tissue sarcomas is very limited in distribution. Am J Clin Pathol. 2002 Feb; 117(2):188-93.
    View in: PubMed
    Score: 0.279
  20. Baranov E, McBride MJ, Bellizzi AM, Ligon AH, Fletcher CDM, Kadoch C, Hornick JL. A Novel SS18-SSX Fusion-specific Antibody for the Diagnosis of Synovial Sarcoma. Am J Surg Pathol. 2020 Jul; 44(7):922-933.
    View in: PubMed
    Score: 0.250
  21. Shanmugam V, Griffin GK, Jacobsen ED, Fletcher CDM, Sholl LM, Hornick JL. Identification of diverse activating mutations of the RAS-MAPK pathway in histiocytic sarcoma. Mod Pathol. 2019 06; 32(6):830-843.
    View in: PubMed
    Score: 0.226
  22. Jo VY, Mariño-Enríquez A, Fletcher CDM, Hornick JL. Expression of PAX3 Distinguishes Biphenotypic Sinonasal Sarcoma From Histologic Mimics. Am J Surg Pathol. 2018 10; 42(10):1275-1285.
    View in: PubMed
    Score: 0.222
  23. Hung YP, Fletcher CDM, Hornick JL. Evaluation of pan-TRK immunohistochemistry in infantile fibrosarcoma, lipofibromatosis-like neural tumour and histological mimics. Histopathology. 2018 Oct; 73(4):634-644.
    View in: PubMed
    Score: 0.218
  24. Hung YP, Fletcher CD, Hornick JL. FOSB is a Useful Diagnostic Marker for Pseudomyogenic Hemangioendothelioma. Am J Surg Pathol. 2017 May; 41(5):596-606.
    View in: PubMed
    Score: 0.201
  25. Schaefer IM, Agaimy A, Fletcher CD, Hornick JL. Claudin-4 expression distinguishes SWI/SNF complex-deficient undifferentiated carcinomas from sarcomas. Mod Pathol. 2017 04; 30(4):539-548.
    View in: PubMed
    Score: 0.197
  26. Hung YP, Fletcher CD, Hornick JL. Evaluation of ETV4 and WT1 expression in CIC-rearranged sarcomas and histologic mimics. Mod Pathol. 2016 11; 29(11):1324-1334.
    View in: PubMed
    Score: 0.190
  27. Hung YP, Fletcher CD, Hornick JL. Evaluation of NKX2-2 expression in round cell sarcomas and other tumors with EWSR1 rearrangement: imperfect specificity for Ewing sarcoma. Mod Pathol. 2016 Apr; 29(4):370-80.
    View in: PubMed
    Score: 0.184
  28. Doyle LA, Fletcher CD, Hornick JL. Nuclear Expression of CAMTA1 Distinguishes Epithelioid Hemangioendothelioma From Histologic Mimics. Am J Surg Pathol. 2016 Jan; 40(1):94-102.
    View in: PubMed
    Score: 0.183
  29. Schaefer IM, Fletcher CD, Hornick JL. Loss of H3K27 trimethylation distinguishes malignant peripheral nerve sheath tumors from histologic mimics. Mod Pathol. 2016 Jan; 29(1):4-13.
    View in: PubMed
    Score: 0.182
  30. Griffin GK, Sholl LM, Lindeman NI, Fletcher CD, Hornick JL. Targeted genomic sequencing of follicular dendritic cell sarcoma reveals recurrent alterations in NF-?B regulatory genes. Mod Pathol. 2016 Jan; 29(1):67-74.
    View in: PubMed
    Score: 0.181
  31. Doyle LA, Mariño-Enriquez A, Fletcher CD, Hornick JL. ALK rearrangement and overexpression in epithelioid fibrous histiocytoma. Mod Pathol. 2015 Jul; 28(7):904-12.
    View in: PubMed
    Score: 0.174
  32. Vivero M, Doyle LA, Fletcher CD, Mertens F, Hornick JL. GRIA2 is a novel diagnostic marker for solitary fibrous tumour identified through gene expression profiling. Histopathology. 2014 Jul; 65(1):71-80.
    View in: PubMed
    Score: 0.162
  33. Doyle LA, Hornick JL, Fletcher CD. PEComa of the gastrointestinal tract: clinicopathologic study of 35 cases with evaluation of prognostic parameters. Am J Surg Pathol. 2013 Dec; 37(12):1769-82.
    View in: PubMed
    Score: 0.158
  34. Doyle LA, Vivero M, Fletcher CD, Mertens F, Hornick JL. Nuclear expression of STAT6 distinguishes solitary fibrous tumor from histologic mimics. Mod Pathol. 2014 Mar; 27(3):390-5.
    View in: PubMed
    Score: 0.156
  35. Jo VY, Antonescu CR, Zhang L, Dal Cin P, Hornick JL, Fletcher CD. Cutaneous syncytial myoepithelioma: clinicopathologic characterization in a series of 38 cases. Am J Surg Pathol. 2013 May; 37(5):710-8.
    View in: PubMed
    Score: 0.152
  36. Antonescu CR, Romeo S, Zhang L, Nafa K, Hornick JL, Nielsen GP, Mino-Kenudson M, Huang HY, Mosquera JM, Dei Tos PA, Fletcher CD. Dedifferentiation in gastrointestinal stromal tumor to an anaplastic KIT-negative phenotype: a diagnostic pitfall: morphologic and molecular characterization of 8 cases occurring either de novo or after imatinib therapy. Am J Surg Pathol. 2013 Mar; 37(3):385-92.
    View in: PubMed
    Score: 0.150
  37. Doyle LA, Wang WL, Dal Cin P, Lopez-Terrada D, Mertens F, Lazar AJ, Fletcher CD, Hornick JL. MUC4 is a sensitive and extremely useful marker for sclerosing epithelioid fibrosarcoma: association with FUS gene rearrangement. Am J Surg Pathol. 2012 Oct; 36(10):1444-51.
    View in: PubMed
    Score: 0.146
  38. Sioletic S, Dal Cin P, Fletcher CD, Hornick JL. Well-differentiated and dedifferentiated liposarcomas with prominent myxoid stroma: analysis of 56 cases. Histopathology. 2013 Jan; 62(2):287-93.
    View in: PubMed
    Score: 0.146
  39. Chen BJ, Mariño-Enríquez A, Fletcher CD, Hornick JL. Loss of retinoblastoma protein expression in spindle cell/pleomorphic lipomas and cytogenetically related tumors: an immunohistochemical study with diagnostic implications. Am J Surg Pathol. 2012 Aug; 36(8):1119-28.
    View in: PubMed
    Score: 0.144
  40. Doyle LA, Möller E, Dal Cin P, Fletcher CD, Mertens F, Hornick JL. MUC4 is a highly sensitive and specific marker for low-grade fibromyxoid sarcoma. Am J Surg Pathol. 2011 May; 35(5):733-41.
    View in: PubMed
    Score: 0.132
  41. Mariño-Enríquez A, Wang WL, Roy A, Lopez-Terrada D, Lazar AJ, Fletcher CD, Coffin CM, Hornick JL. Epithelioid inflammatory myofibroblastic sarcoma: An aggressive intra-abdominal variant of inflammatory myofibroblastic tumor with nuclear membrane or perinuclear ALK. Am J Surg Pathol. 2011 Jan; 35(1):135-44.
    View in: PubMed
    Score: 0.129
  42. Mariño-Enríquez A, Fletcher CD, Dal Cin P, Hornick JL. Dedifferentiated liposarcoma with "homologous" lipoblastic (pleomorphic liposarcoma-like) differentiation: clinicopathologic and molecular analysis of a series suggesting revised diagnostic criteria. Am J Surg Pathol. 2010 Aug; 34(8):1122-31.
    View in: PubMed
    Score: 0.126
  43. Liegl B, Hornick JL, Corless CL, Fletcher CD. Monoclonal antibody DOG1.1 shows higher sensitivity than KIT in the diagnosis of gastrointestinal stromal tumors, including unusual subtypes. Am J Surg Pathol. 2009 Mar; 33(3):437-46.
    View in: PubMed
    Score: 0.114
  44. Liegl B, Hornick JL, Antonescu CR, Corless CL, Fletcher CD. Rhabdomyosarcomatous differentiation in gastrointestinal stromal tumors after tyrosine kinase inhibitor therapy: a novel form of tumor progression. Am J Surg Pathol. 2009 Feb; 33(2):218-26.
    View in: PubMed
    Score: 0.113
  45. Liegl B, Hornick JL, Fletcher CD. Primary cutaneous PEComa: distinctive clear cell lesions of skin. Am J Surg Pathol. 2008 Apr; 32(4):608-14.
    View in: PubMed
    Score: 0.107
  46. Coffin CM, Hornick JL, Fletcher CD. Inflammatory myofibroblastic tumor: comparison of clinicopathologic, histologic, and immunohistochemical features including ALK expression in atypical and aggressive cases. Am J Surg Pathol. 2007 Apr; 31(4):509-20.
    View in: PubMed
    Score: 0.100
  47. Coffin CM, Hornick JL, Zhou H, Fletcher CD. Gardner fibroma: a clinicopathologic and immunohistochemical analysis of 45 patients with 57 fibromas. Am J Surg Pathol. 2007 Mar; 31(3):410-6.
    View in: PubMed
    Score: 0.099
  48. Carter MR, Hornick JL, Lester S, Fletcher CD. Spindle cell (sarcomatoid) carcinoma of the breast: a clinicopathologic and immunohistochemical analysis of 29 cases. Am J Surg Pathol. 2006 Mar; 30(3):300-9.
    View in: PubMed
    Score: 0.093
  49. Medeiros F, Corless CL, Duensing A, Hornick JL, Oliveira AM, Heinrich MC, Fletcher JA, Fletcher CD. KIT-negative gastrointestinal stromal tumors: proof of concept and therapeutic implications. Am J Surg Pathol. 2004 Jul; 28(7):889-94.
    View in: PubMed
    Score: 0.083
  50. Nascimento AF, Ruiz R, Hornick JL, Fletcher CD. Calcifying fibrous 'pseudotumor': clinicopathologic study of 15 cases and analysis of its relationship to inflammatory myofibroblastic tumor. Int J Surg Pathol. 2002 Jul; 10(3):189-96.
    View in: PubMed
    Score: 0.072
  51. Kolin DL, Quick CM, Dong F, Fletcher CDM, Stewart CJR, Soma A, Hornick JL, Nucci MR, Howitt BE. SMARCA4-deficient Uterine Sarcoma and Undifferentiated Endometrial Carcinoma Are Distinct Clinicopathologic Entities. Am J Surg Pathol. 2020 02; 44(2):263-270.
    View in: PubMed
    Score: 0.061
  52. Mito JK, Bishop JA, Sadow PM, Stelow EB, Faquin WC, Mills SE, Krane JF, French CA, Fletcher CDM, Hornick JL, Sholl LM, Jo VY. Immunohistochemical Detection and Molecular Characterization of IDH-mutant Sinonasal Undifferentiated Carcinomas. Am J Surg Pathol. 2018 08; 42(8):1067-1075.
    View in: PubMed
    Score: 0.055
  53. Tian X, Xu J, Fletcher C, Hornick JL, Dorfman DM. Expression of enhancer of zeste homolog 2 (EZH2) protein in histiocytic and dendritic cell neoplasms with evidence for p-ERK1/2-related, but not MYC- or p-STAT3-related cell signaling. Mod Pathol. 2018 04; 31(4):553-561.
    View in: PubMed
    Score: 0.053
  54. Schaefer IM, Hornick JL, Barysauskas CM, Raut CP, Patel SA, Royce TJ, Fletcher CDM, Baldini EH. Histologic Appearance After Preoperative Radiation Therapy for Soft Tissue Sarcoma: Assessment of the European Organization for Research and Treatment of Cancer-Soft Tissue and Bone Sarcoma Group Response Score. Int J Radiat Oncol Biol Phys. 2017 06 01; 98(2):375-383.
    View in: PubMed
    Score: 0.050
  55. Xu J, Sun HH, Fletcher CD, Hornick JL, Morgan EA, Freeman GJ, Hodi FS, Pinkus GS, Rodig SJ. Expression of Programmed Cell Death 1 Ligands (PD-L1 and PD-L2) in Histiocytic and Dendritic Cell Disorders. Am J Surg Pathol. 2016 Apr; 40(4):443-53.
    View in: PubMed
    Score: 0.047
  56. Wojcik JB, Bellizzi AM, Dal Cin P, Bredella MA, Fletcher CD, Hornicek FJ, Deshpande V, Hornick JL, Nielsen GP. Primary sclerosing epithelioid fibrosarcoma of bone: analysis of a series. Am J Surg Pathol. 2014 Nov; 38(11):1538-44.
    View in: PubMed
    Score: 0.042
  57. Al-Zaid T, Wang WL, Lopez-Terrada D, Lev D, Hornick JL, Hafeez Diwan A, Fletcher CD, Lazar AJ. Pleomorphic fibroma and dermal atypical lipomatous tumor: are they related? J Cutan Pathol. 2013 Apr; 40(4):379-84.
    View in: PubMed
    Score: 0.038
  58. Trombetta D, Magnusson L, von Steyern FV, Hornick JL, Fletcher CD, Mertens F. Translocation t(7;19)(q22;q13)-a recurrent chromosome aberration in pseudomyogenic hemangioendothelioma? Cancer Genet. 2011 Apr; 204(4):211-5.
    View in: PubMed
    Score: 0.033
  59. Saab ST, Hornick JL, Fletcher CD, Olson SJ, Coffin CM. IgG4 plasma cells in inflammatory myofibroblastic tumor: inflammatory marker or pathogenic link? Mod Pathol. 2011 Apr; 24(4):606-12.
    View in: PubMed
    Score: 0.033
  60. Savage K, Lambros MB, Robertson D, Jones RL, Jones C, Mackay A, James M, Hornick JL, Pereira EM, Milanezi F, Fletcher CD, Schmitt FC, Ashworth A, Reis-Filho JS. Caveolin 1 is overexpressed and amplified in a subset of basal-like and metaplastic breast carcinomas: a morphologic, ultrastructural, immunohistochemical, and in situ hybridization analysis. Clin Cancer Res. 2007 Jan 01; 13(1):90-101.
    View in: PubMed
    Score: 0.025
  61. Reis-Filho JS, Pinheiro C, Lambros MB, Milanezi F, Carvalho S, Savage K, Simpson PT, Jones C, Swift S, Mackay A, Reis RM, Hornick JL, Pereira EM, Baltazar F, Fletcher CD, Ashworth A, Lakhani SR, Schmitt FC. EGFR amplification and lack of activating mutations in metaplastic breast carcinomas. J Pathol. 2006 Aug; 209(4):445-53.
    View in: PubMed
    Score: 0.024
  62. Carrasco DR, Fenton T, Sukhdeo K, Protopopova M, Enos M, You MJ, Di Vizio D, Divicio D, Nogueira C, Stommel J, Pinkus GS, Fletcher C, Hornick JL, Cavenee WK, Furnari FB, Depinho RA. The PTEN and INK4A/ARF tumor suppressors maintain myelolymphoid homeostasis and cooperate to constrain histiocytic sarcoma development in humans. Cancer Cell. 2006 May; 9(5):379-90.
    View in: PubMed
    Score: 0.023
  63. Duensing A, Joseph NE, Medeiros F, Smith F, Hornick JL, Heinrich MC, Corless CL, Demetri GD, Fletcher CD, Fletcher JA. Protein Kinase C theta (PKCtheta) expression and constitutive activation in gastrointestinal stromal tumors (GISTs). Cancer Res. 2004 Aug 01; 64(15):5127-31.
    View in: PubMed
    Score: 0.021
  64. Johnson BE, Fischer T, Fischer B, Dunlop D, Rischin D, Silberman S, Kowalski MO, Sayles D, Dimitrijevic S, Fletcher C, Hornick J, Salgia R, Le Chevalier T. Phase II study of imatinib in patients with small cell lung cancer. Clin Cancer Res. 2003 Dec 01; 9(16 Pt 1):5880-7.
    View in: PubMed
    Score: 0.020
  65. George S, Hornick JL, Bertagnolli MM, Fletcher CD, Demetri GD. Current management of metastatic gastrointestinal stromal tumor: a case report. Clin Adv Hematol Oncol. 2003 Jan; 1(1):63-4; discussion 65.
    View in: PubMed
    Score: 0.019
Connection Strength
The connection strength for co-authors is the sum of the scores for each of their shared publications.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.
Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.