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Kai Uwe Frerichs, M.D.

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Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Cerecedo-Lopez CD, Cantu-Aldana A, Patel NJ, Aziz-Sultan MA, Frerichs KU, Du R. Insulin in the Management of Acute Ischemic Stroke: A Systematic Review and Meta-Analysis. World Neurosurg. 2020 Apr; 136:e514-e534. PMID: 31954893.
    Citations:    
  2. Dasenbrock HH, Smith TR, Gormley WB, Castlen JP, Patel NJ, Frerichs KU, Aziz-Sultan MA, Du R. Predictive Score of Adverse Events After Carotid Endarterectomy: The NSQIP Registry Carotid Endarterectomy Scale. J Am Heart Assoc. 2019 11 05; 8(21):e013412. PMID: 31662028.
    Citations:    
  3. Subat YW, Dasenbrock HH, Gross BA, Patel NJ, Frerichs KU, Du R, Aziz-Sultan MA. Periprocedural intracranial hemorrhage after embolization of cerebral arteriovenous malformations: a meta-analysis. J Neurosurg. 2019 Sep 13; 1-11. PMID: 31518979.
    Citations:    
  4. Lai PMR, Gormley WB, Patel N, Frerichs KU, Aziz-Sultan MA, Du R. Age-Dependent Radiographic Vasospasm and Delayed Cerebral Ischemia in Women After Aneurysmal Subarachnoid Hemorrhage. World Neurosurg. 2019 Oct; 130:e230-e235. PMID: 31203057.
    Citations:    
  5. Dasenbrock HH, See AP, Smalley RJ, Bi WL, Dolati P, Frerichs KU, Golby AJ, Chiocca EA, Aziz-Sultan MA. Frameless Stereotactic Navigation during Insular Glioma Resection using Fusion of Three-Dimensional Rotational Angiography and Magnetic Resonance Imaging. World Neurosurg. 2019 Jun; 126:322-330. PMID: 30898738.
    Citations:    
  6. Dasenbrock HH, Rudy RF, Smith TR, Gormley WB, Patel NJ, Frerichs KU, Aziz-Sultan MA, Du R. Adverse events after clipping of unruptured intracranial aneurysms: the NSQIP unruptured aneurysm scale. J Neurosurg. 2019 Mar 15; 1-10. PMID: 30875693.
    Citations:    
  7. Dasenbrock HH, Rudy RF, Gormley WB, Frerichs KU, Aziz-Sultan MA, Du R. The Timing of Tracheostomy and Outcomes After Aneurysmal Subarachnoid Hemorrhage: A Nationwide Inpatient Sample Analysis. Neurocrit Care. 2018 12; 29(3):326-335. PMID: 30298335.
    Citations:    
  8. Lai PMR, See AP, Silva MA, Gormley WB, Frerichs KU, Aziz-Sultan MA, Du R. Noninfectious Fever in Aneurysmal Subarachnoid Hemorrhage: Association with Cerebral Vasospasm and Clinical Outcome. World Neurosurg. 2019 Feb; 122:e1014-e1019. PMID: 30414522.
    Citations:    Fields:    
  9. Lin N, Cahill KS, Frerichs KU, Friedlander RM, Claus EB. Treatment of ruptured and unruptured cerebral aneurysms in the USA: a paradigm shift. J Neurointerv Surg. 2018 Jul; 10(Suppl 1):i69-i76. PMID: 30037962.
    Citations:    Fields:    Translation:Humans
  10. Silva MA, See AP, Khandelwal P, Mahapatra A, Frerichs KU, Du R, Patel NJ, Aziz-Sultan MA. Comparison of flow diversion with clipping and coiling for the treatment of paraclinoid aneurysms in 115 patients. J Neurosurg. 2018 Jun 01; 1-8. PMID: 29932380.
    Citations:    Fields:    
  11. Dasenbrock HH, Rudy RF, Rosalind Lai PM, Smith TR, Frerichs KU, Gormley WB, Aziz-Sultan MA, Du R. Cigarette smoking and outcomes after aneurysmal subarachnoid hemorrhage: a nationwide analysis. J Neurosurg. 2018 08; 129(2):446-457. PMID: 29076779.
    Citations: 1     Fields:    
  12. Dasenbrock HH, Angriman F, Smith TR, Gormley WB, Frerichs KU, Aziz-Sultan MA, Du R. Readmission After Aneurysmal Subarachnoid Hemorrhage: A Nationwide Readmission Database Analysis. Stroke. 2017 09; 48(9):2383-2390. PMID: 28754828.
    Citations:    Fields:    Translation:Humans
  13. Dasenbrock HH, Rudy RF, Gormley WB, Smith TR, Frerichs KU, Aziz-Sultan MA, Du R. 111 Predictors of Complications After Clipping of Unruptured Intracranial Aneurysms: A National Surgical Quality Improvement Program Analysis. Neurosurgery. 2016 Aug; 63 Suppl 1:147. PMID: 27399391.
    Citations:    
  14. Dasenbrock HH, Smith TR, Gormley WB, Frerichs KU, Aziz-Sultan MA, Du R. 108 Adverse Events After Carotid Endarterectomy: A National Surgical Quality Improvement Program Analysis. Neurosurgery. 2016 Aug; 63 Suppl 1:146. PMID: 27399388.
    Citations:    
  15. Dasenbrock HH, Nguyen MO, Frerichs KU, Guttieres D, Gormley WB, Ali Aziz-Sultan M, Du R. The impact of body habitus on outcomes after aneurysmal subarachnoid hemorrhage: a Nationwide Inpatient Sample analysis. J Neurosurg. 2017 Jul; 127(1):36-46. PMID: 27419827.
    Citations:    Fields:    
  16. See AP, Gross BA, Penn DL, Du R, Frerichs KU. Hemodynamic Impact of a Spontaneous Cervical Dissection on an Ipsilateral Saccular Aneurysm. J Cerebrovasc Endovasc Neurosurg. 2016 Jun; 18(2):110-114. PMID: 27790401.
    Citations:    
  17. Silva MA, See AP, Dasenbrock HH, Ashour R, Khandelwal P, Patel NJ, Frerichs KU, Aziz-Sultan MA. Stent deployment protocol for optimized real-time visualization during endovascular neurosurgery. J Neurosurg. 2017 May; 126(5):1614-1621. PMID: 27341046.
    Citations:    Fields:    
  18. Dasenbrock HH, Yan SC, Gross BA, Guttieres D, Gormley WB, Frerichs KU, Ali Aziz-Sultan M, Du R. The impact of aspirin and anticoagulant usage on outcomes after aneurysmal subarachnoid hemorrhage: a Nationwide Inpatient Sample analysis. J Neurosurg. 2017 Feb; 126(2):537-547. PMID: 27058205.
    Citations: 3     Fields:    
  19. Dasenbrock HH, Bartolozzi AR, Gormley WB, Frerichs KU, Aziz-Sultan MA, Du R. Clostridium difficile Infection After Subarachnoid Hemorrhage: A Nationwide Analysis. Neurosurgery. 2016 Mar; 78(3):412-20. PMID: 26485334.
    Citations:    Fields:    Translation:HumansCells
  20. Dasenbrock HH, Rudy RF, Smith TR, Guttieres D, Frerichs KU, Gormley WB, Aziz-Sultan MA, Du R. Hospital-Acquired Infections after Aneurysmal Subarachnoid Hemorrhage: A Nationwide Analysis. World Neurosurg. 2016 Apr; 88:459-474. PMID: 26546996.
    Citations: 3     Fields:    Translation:Humans
  21. Ho AL, Lin N, Frerichs KU, Du R. Intrinsic, Transitional, and Extrinsic Morphological Factors Associated With Rupture of Intracranial Aneurysms. Neurosurgery. 2015 Sep; 77(3):433-41; discussion 441-2. PMID: 26075307.
    Citations: 1     Fields:    Translation:Humans
  22. Ho AL, Lin N, Frerichs KU, Du R. Smoking and Intracranial Aneurysm Morphology. Neurosurgery. 2015 Jul; 77(1):59-66; discussion 66. PMID: 25839377.
    Citations:    
  23. De Los Reyes KM, Gross BA, Frerichs KU, Dunn IF, Lin N, Rincon-Torroella J, Annino DJ, Laws ER. Incidence, risk factors and management of severe post-transsphenoidal epistaxis. J Clin Neurosci. 2015 Jan; 22(1):116-22. PMID: 25150759.
    Citations: 1     Fields:    Translation:Humans
  24. Yanamadala V, Lin N, Zarzour H, Frerichs KU, Walcott BP, Thomas AJ, Puri AS. Endovascular coiling of a ruptured basilar apex aneurysm with associated pseudoaneurysm. J Clin Neurosci. 2014 Sep; 21(9):1637-40. PMID: 24768151.
    Citations: 1     Fields:    Translation:Humans
  25. Ho A, Lin N, Charoenvimolphan N, Stanley M, Frerichs KU, Day AL, Du R. Morphological parameters associated with ruptured posterior communicating aneurysms. PLoS One. 2014; 9(4):e94837. PMID: 24733151.
    Citations: 5     Fields:    Translation:Humans
  26. Gross BA, Thomas AJ, Frerichs KU. Endovascular treatment of symptomatic moyamoya. Neurosurg Rev. 2014 Oct; 37(4):579-83. PMID: 24696002.
    Citations:    Fields:    Translation:Humans
  27. Thiex R, Gross BA, Gupta R, Wyers MC, Frerichs KU, Thomas AJ. Transvenous approach to carotid-cavernous fistula via facial vein cut down. J Clin Neurosci. 2014 Jul; 21(7):1238-40. PMID: 24387933.
    Citations:    Fields:    Translation:Humans
  28. Lin N, Ho A, Charoenvimolphan N, Frerichs KU, Day AL, Du R. Analysis of morphological parameters to differentiate rupture status in anterior communicating artery aneurysms. PLoS One. 2013; 8(11):e79635. PMID: 24236149.
    Citations: 9     Fields:    Translation:Humans
  29. Agarwalla PK, Walcott BP, Dunn IF, Thiex R, Frerichs K, Narang S, Friedlander RM. Fusiform aneurysms of the lenticulostriate artery. J Clin Neurosci. 2014 Mar; 21(3):373-7. PMID: 24156904.
    Citations: 1     Fields:    Translation:Humans
  30. Chavakula V, Gross BA, Frerichs KU, Du R. Contrast-induced nephropathy in patients with aneurysmal subarachnoid hemorrhage. Neurocrit Care. 2013 Oct; 19(2):157-60. PMID: 23839706.
    Citations: 3     Fields:    Translation:Humans
  31. Gross BA, Rosalind Lai PM, Frerichs KU, Du R. Treatment modality and vasospasm after aneurysmal subarachnoid hemorrhage. World Neurosurg. 2014 Dec; 82(6):e725-30. PMID: 23954735.
    Citations: 3     Fields:    Translation:Humans
  32. Gross BA, Frerichs KU, Du R. Microsurgical treatment of a ruptured dissecting labyrinthine artery aneurysm. Clin Neurol Neurosurg. 2013 Oct; 115(10):2277-9. PMID: 23932471.
    Citations: 1     Fields:    Translation:Humans
  33. Gross BA, Frerichs KU. The natural history of cerebrovascular disease: a closer look at paraclinoid aneurysms and epileptogenic AVMs. J Neurol Neurosurg Psychiatry. 2014 Mar; 85(3):247. PMID: 23868945.
    Citations:    Fields:    Translation:Humans
  34. Gross BA, Lai PM, Frerichs KU, Du R. Angiotensin-converting enzyme-inhibitors, statins and the risk of hemorrhage from cerebral dural arteriovenous fistulae. J Clin Neurosci. 2013 Sep; 20(9):1228-31. PMID: 23706184.
    Citations:    Fields:    Translation:Humans
  35. Gross BA, Thomas AJ, Frerichs KU, Du R. Cerebrovascular neurosurgery in 2012. J Clin Neurosci. 2013 Jun; 20(6):776-82. PMID: 23632292.
    Citations: 2     Fields:    Translation:Humans
  36. Wong JM, Ho AL, Lin N, Zenonos GA, Martel CB, Frerichs K, Du R, Gormley WB. Radiation exposure in patients with subarachnoid hemorrhage: a quality improvement target. J Neurosurg. 2013 Jul; 119(1):215-20. PMID: 23621604.
    Citations: 1     Fields:    Translation:HumansPHPublic Health
  37. Gross BA, Rosalind Lai PM, Frerichs KU, Du R. Aspirin and aneurysmal subarachnoid hemorrhage. World Neurosurg. 2014 Dec; 82(6):1127-30. PMID: 23548847.
    Citations: 8     Fields:    Translation:Humans
  38. Thiex R, Harris MB, Sides C, Bono CM, Frerichs KU. The role of preoperative transarterial embolization in spinal tumors. A large single-center experience. Spine J. 2013 Feb; 13(2):141-9. PMID: 23218826.
    Citations: 8     Fields:    Translation:Humans
  39. Gross BA, Frerichs KU. Stent usage in the treatment of intracranial aneurysms: past, present and future. J Neurol Neurosurg Psychiatry. 2013 Mar; 84(3):244-53. PMID: 23138770.
    Citations: 11     Fields:    Translation:Humans
  40. Wong JM, Ziewacz JE, Panchmatia JR, Bader AM, Pandey AS, Thompson BG, Frerichs K, Gawande AA. Patterns in neurosurgical adverse events: endovascular neurosurgery. Neurosurg Focus. 2012 Nov; 33(5):E14. PMID: 23116094.
    Citations: 3     Fields:    Translation:Humans
  41. Lin N, Ho A, Gross BA, Pieper S, Frerichs KU, Day AL, Du R. Differences in simple morphological variables in ruptured and unruptured middle cerebral artery aneurysms. J Neurosurg. 2012 Nov; 117(5):913-9. PMID: 22957531.
    Citations: 17     Fields:    Translation:Humans
  42. Puri AS, Zada G, Zarzour H, Laws E, Frerichs K. Cerebral vasospasm after transsphenoidal resection of pituitary macroadenomas: report of 3 cases and review of the literature. Neurosurgery. 2012 Sep; 71(1 Suppl Operative):173-80; discussion 180-1. PMID: 22249952.
    Citations: 5     Fields:    Translation:Humans
  43. Gross BA, Frerichs KU, Du R. Sensitivity of CT angiography, T2-weighted MRI, and magnetic resonance angiography in detecting cerebral arteriovenous malformations and associated aneurysms. J Clin Neurosci. 2012 Aug; 19(8):1093-5. PMID: 22705129.
    Citations: 5     Fields:    Translation:Humans
  44. Wang H, Du R, Stary J, Gkogkas C, Kim D, Day A, Frerichs K. Dissecting aneurysms of the posterior cerebral artery: current endovascular/surgical evaluation and treatment strategies. Neurosurgery. 2012 Jun; 70(6):1581-8; discussion 1588. PMID: 22273602.
    Citations: 3     Fields:    Translation:Humans
  45. Lin N, Zenonos G, Kim AH, Nalbach SV, Du R, Frerichs KU, Friedlander RM, Gormley WB. Angiogram-negative subarachnoid hemorrhage: relationship between bleeding pattern and clinical outcome. Neurocrit Care. 2012 Jun; 16(3):389-98. PMID: 22350856.
    Citations: 7     Fields:    Translation:Humans
  46. Gross BA, Lin N, Frerichs KU, Du R. Vasospasm after spontaneous angiographically negative subarachnoid hemorrhage. Acta Neurochir (Wien). 2012 Jul; 154(7):1127-33. PMID: 22588341.
    Citations: 4     Fields:    Translation:Humans
  47. Ropper AE, Lin N, Gross BA, Zarzour HK, Thiex R, Chi JH, Du R, Frerichs KU. Rotational angiography for diagnosis and surgical planning in the management of spinal vascular lesions. Neurosurg Focus. 2012 May; 32(5):E6. PMID: 22537132.
    Citations: 1     Fields:    Translation:Humans
  48. Lin N, Cahill KS, Frerichs KU, Friedlander RM, Claus EB. Treatment of ruptured and unruptured cerebral aneurysms in the USA: a paradigm shift. J Neurointerv Surg. 2012 May; 4(3):182-9. PMID: 21990481.
    Citations: 17     Fields:    Translation:Humans
  49. Thiex R, Norbash AM, Frerichs KU. The safety of dedicated-team catheter-based diagnostic cerebral angiography in the era of advanced noninvasive imaging. AJNR Am J Neuroradiol. 2010 Feb; 31(2):230-4. PMID: 19779004.
    Citations: 18     Fields:    Translation:Humans
  50. Fennessy BG, Kozakewich HP, Silvera M, Frerichs K, Lillhei CW, Poe D, Rahbar R. The presentation and management of multiple paraganglioma in head and neck. Ir J Med Sci. 2011 Sep; 180(3):757-60. PMID: 19421704.
    Citations: 3     Fields:    Translation:Humans
  51. Pujol S, Frerichs K, Norbash A, Kikinis R, Westin CF. Preliminary results of nonfluoroscopy-based 3D navigation for neurointerventional procedures. J Vasc Interv Radiol. 2007 Feb; 18(2):289-98. PMID: 17327564.
    Citations: 1     Fields:    Translation:Humans
  52. Dunn IF, Chumnanvej S, Gormley WB, Friedlander RM, Gkogkas C, Frerichs KU, Day AL, Kim DH. Comparison of Computed Tomographic Angiography and Digital Subtraction Angiography in the Initial Management of Patients with Subarachnoid Hemorrhage 809. Neurosurgery. 2006 Aug 01; 59(2):456. PMID: 28180636.
    Citations:    
  53. Kacher DF, Frerichs K, Pettit J, Campbell PK, Meunch T, Norbash AM. DuraSeal magnetic resonance and computed tomography imaging: evaluation in a canine craniotomy model. Neurosurgery. 2006 Feb; 58(1 Suppl):ONS140-7; discussion ONS140-7. PMID: 16543872.
    Citations: 5     Fields:    Translation:Animals
  54. Chen P, Dunn IF, Aglio LS, Day AL, Frerichs KU, Friedlander RM. Intraoperative awakening for vision examination during ophthalmic artery aneurysm clipping: technical case report. Neurosurgery. 2005 Apr; 56(2 Suppl):E440; discussion E440. PMID: 15794844.
    Citations: 3     Fields:    Translation:HumansCells
  55. Chen PR, Frerichs K, Spetzler R. Current treatment options for unruptured intracranial aneurysms. Neurosurg Focus. 2004 Nov 15; 17(5):E5. PMID: 15633982.
    Citations:    Fields:    Translation:Humans
  56. Chen PR, Frerichs K, Spetzler R. Natural history and general management of unruptured intracranial aneurysms. Neurosurg Focus. 2004 Nov 15; 17(5):E1. PMID: 15633974.
    Citations: 1     Fields:    Translation:Humans
  57. Frerichs K, Baker J, Norbash A. Intra-arterial stroke thrombolysis and carotid stenting: methods for the treatment of ischemic cerebrovascular disease. Semin Roentgenol. 2002 Oct; 37(4):255-65. PMID: 12455124.
    Citations:    Fields:    Translation:Humans
  58. Chen Y, Matsushita M, Nairn AC, Damuni Z, Cai D, Frerichs KU, Hallenbeck JM. Mechanisms for increased levels of phosphorylation of elongation factor-2 during hibernation in ground squirrels. Biochemistry. 2001 Sep 25; 40(38):11565-70. PMID: 11560506.
    Citations: 17     Fields:    Translation:AnimalsCells
  59. Frerichs KU, Stieg PE, Friedlander RM. Prediction of aneurysm rupture site by an angiographically identified bleb at the aneurysm neck. J Neurosurg. 2000 Sep; 93(3):517. PMID: 10969960.
    Citations:    Fields:    Translation:Humans
  60. Drew KL, Osborne PG, Frerichs KU, Hu Y, Koren RE, Hallenbeck JM, Rice ME. Ascorbate and glutathione regulation in hibernating ground squirrels. Brain Res. 1999 Dec 18; 851(1-2):1-8. PMID: 10642822.
    Citations: 12     Fields:    Translation:Animals
  61. Frerichs KU. Neuroprotective strategies in nature--novel clues for the treatment of stroke and trauma. Acta Neurochir Suppl. 1999; 73:57-61. PMID: 10494342.
    Citations: 7     Fields:    Translation:AnimalsCells
  62. Frerichs KU, Smith CB, Brenner M, DeGracia DJ, Krause GS, Marrone L, Dever TE, Hallenbeck JM. Suppression of protein synthesis in brain during hibernation involves inhibition of protein initiation and elongation. Proc Natl Acad Sci U S A. 1998 Nov 24; 95(24):14511-6. PMID: 9826731.
    Citations: 67     Fields:    Translation:AnimalsCells
  63. Ohtsuki T, Jaffe H, Brenner M, Azzam N, Azzam R, Frerichs KU, Hallenbeck JM. Stimulation of tyrosine phosphorylation of a brain protein by hibernation. J Cereb Blood Flow Metab. 1998 Sep; 18(9):1040-5. PMID: 9740108.
    Citations: 3     Fields:    Translation:AnimalsCells
  64. Frerichs KU, Hallenbeck JM. Hibernation in ground squirrels induces state and species-specific tolerance to hypoxia and aglycemia: an in vitro study in hippocampal slices. J Cereb Blood Flow Metab. 1998 Feb; 18(2):168-75. PMID: 9469159.
    Citations: 46     Fields:    Translation:AnimalsCells
  65. Lindsberg PJ, Frerichs KU, Sirén AL, Hallenbeck JM, Nowak TS. Heat-shock protein and C-fos expression in focal microvascular brain damage. J Cereb Blood Flow Metab. 1996 Jan; 16(1):82-91. PMID: 8530560.
    Citations:    
  66. Frerichs KU, Dienel GA, Cruz NF, Sokoloff L, Hallenbeck JM. Rates of glucose utilization in brain of active and hibernating ground squirrels. Am J Physiol. 1995 Feb; 268(2 Pt 2):R445-53. PMID: 7864240.
    Citations: 10     Fields:    Translation:Animals
  67. Frerichs KU, Kennedy C, Sokoloff L, Hallenbeck JM. Local cerebral blood flow during hibernation, a model of natural tolerance to "cerebral ischemia". J Cereb Blood Flow Metab. 1994 Mar; 14(2):193-205. PMID: 8113316.
    Citations: 61     Fields:    Translation:AnimalsCells
  68. Frerichs KU, Sirén AL, Feuerstein GZ, Hallenbeck JM. The onset of postischemic hypoperfusion in rats is precipitous and may be controlled by local neurons. Stroke. 1992 Mar; 23(3):399-406. PMID: 1542903.
    Citations: 2     Fields:    Translation:AnimalsCells
  69. Lindsberg PJ, Yue TL, Frerichs KU, Hallenbeck JM, Feuerstein G. Evidence for platelet-activating factor as a novel mediator in experimental stroke in rabbits. Stroke. 1990 Oct; 21(10):1452-7. PMID: 2219210.
    Citations: 15     Fields:    Translation:Animals
  70. Frerichs KU, Lindsberg PJ, Hallenbeck JM, Feuerstein GZ. Platelet-activating factor and progressive brain damage following focal brain injury. J Neurosurg. 1990 Aug; 73(2):223-33. PMID: 2366079.
    Citations: 6     Fields:    Translation:AnimalsCells
  71. Frerichs KU, Lindsberg PJ, Hallenbeck JM, Feuerstein GZ. Increased cerebral lactate output to cerebral venous blood after forebrain ischemia in rats. Stroke. 1990 Apr; 21(4):614-7. PMID: 2326843.
    Citations: 1     Fields:    Translation:Animals
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.