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Nestor Uribe-Patarroyo, Ph.D.


I am an Assistant Professor at Harvard Medical School and the Wellman Center for Photomedicine at Massachusetts General Hospital, and a faculty member of the Center for Biomedical OCT Research and Translation (CBORT, https://octresearch.org/). I am a physicist by training (Universidad del Valle, Colombia), and received my PhD in Advanced Optics (Universidad Complutense de Madrid, Spain). Before joining Wellman, I worked on optical instrumentation for space science missions and quantum optics. I am a PI with major NIH funding and also manage three sub-projects from the Department of Defense/Air Force Office of Scientific Research. My research is focused on the development of functional imaging and enhanced endogenous contrast in OCT for diagnostics and guided therapy.

The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. R01EB033306 (URIBE-PATARROYO, NESTOR)) Aug 1, 2022 - Apr 30, 2026
    Intravascular microstructural, chemical and biomechanical characterization of coronary plaques
    Role Description: The most prevalent type of heart disease is caused by atherosclerosis, the thickening of the vessel wall and creation of atherosclerotic plaque. In this project, we will develop an imaging tool for the compre- hensive assessment of atherosclerotic plaque composition and vulnerability, with a clear pathway for translation into the clinical environment to enable the determination of the optimal treatment strategy in individual patients.
    Role: Principal investigator
  2. P41EB015903 (BOUMA, BRETT) Jul 1, 2022 - Mar 31, 2027
    Center for Biomedical OCT Research and Translation. TRD1: Functional Imaging
    Role Description: The proposed NCBIB will develop and provide broad access to powerful new microscopic imaging tools for biological and clinical research. These instruments will open new avenues of biomedical research and may enable the identification of new methods for diagnosis, provide new insights into disease or disease progression, or lead to the formulation of new therapeutic strategies or drug targets.
    Role: Project Co-Lead
  3. Collaborative Research Travel Grant (URIBE-PATARROYO, NESTOR) Jun 1, 2018 - Dec 31, 2019
    Burroughs Wellcome Fund
    OCT velocimetry for quantifying corneal biomechanics
    Role: Principal Investigator
  4. K25EB024595 (URIBE-PATARROYO, NESTOR) Aug 1, 2017 - May 31, 2022
    Blood flow-based guidance and diagnostics using OCT
    Role Description: Coronary artery disease (CAD) and visual disorders like diabetic retinopathy, macular degeneration and glaucoma are among the leading causes of mortality and morbidity in the US, and are diagnosed using the qualitative assessment of blood flow using invasive dye contrast techniques. This project develops a fully validated flowmetry technique to guide CAD treatment and to provide early eye disease diagnosis, with the potential to extend into a wide range of clinical applications, meeting the large demand for accurate blood flowmetry in healthcare.
    Role: Principal Investigator

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.