Harvard Catalyst Profiles

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Kellen Diamond Winden, M.D.

Concepts

This page shows the publications Kellen Winden has written about Humans.
Connection Strength

0.048
  1. Biallelic Mutations in TSC2 Lead to Abnormalities Associated with Cortical Tubers in Human iPSC-Derived Neurons. J Neurosci. 2019 11 20; 39(47):9294-9305.
    View in: PubMed
    Score: 0.010
  2. Abnormal mTOR Activation in Autism. Annu Rev Neurosci. 2018 07 08; 41:1-23.
    View in: PubMed
    Score: 0.009
  3. Megalencephaly and Macrocephaly. Semin Neurol. 2015 Jun; 35(3):277-87.
    View in: PubMed
    Score: 0.007
  4. 16p11.2 deletion is associated with hyperactivation of human iPSC-derived dopaminergic neuron networks and is rescued by RHOA inhibition in vitro. Nat Commun. 2021 05 18; 12(1):2897.
    View in: PubMed
    Score: 0.003
  5. Subependymal giant cell astrocytomas are characterized by mTORC1 hyperactivation, a very low somatic mutation rate, and a unique gene expression profile. Mod Pathol. 2021 02; 34(2):264-279.
    View in: PubMed
    Score: 0.003
  6. Phenotypic Screen with TSC-Deficient Neurons Reveals Heat-Shock Machinery as a Druggable Pathway for mTORC1 and Reduced Cilia. Cell Rep. 2020 06 23; 31(12):107780.
    View in: PubMed
    Score: 0.003
  7. Purkinje cells derived from TSC patients display hypoexcitability and synaptic deficits associated with reduced FMRP levels and reversed by rapamycin. Mol Psychiatry. 2018 11; 23(11):2167-2183.
    View in: PubMed
    Score: 0.002
  8. Cell-type-specific miR-431 dysregulation in a motor neuron model of spinal muscular atrophy. Hum Mol Genet. 2016 06 01; 25(11):2168-2181.
    View in: PubMed
    Score: 0.002
  9. Stroke in primary hyperoxaluria type I. J Neuroimaging. 2014 Jul-Aug; 24(4):411-3.
    View in: PubMed
    Score: 0.002
  10. Human-specific transcriptional networks in the brain. Neuron. 2012 Aug 23; 75(4):601-17.
    View in: PubMed
    Score: 0.001
  11. Absence of CNTNAP2 leads to epilepsy, neuronal migration abnormalities, and core autism-related deficits. Cell. 2011 Sep 30; 147(1):235-46.
    View in: PubMed
    Score: 0.001
  12. Functional genomic analyses identify pathways dysregulated by progranulin deficiency, implicating Wnt signaling. Neuron. 2011 Sep 22; 71(6):1030-42.
    View in: PubMed
    Score: 0.001
  13. Substrate sequence influences ?-secretase modulator activity, role of the transmembrane domain of the amyloid precursor protein. J Biol Chem. 2011 Nov 18; 286(46):39794-803.
    View in: PubMed
    Score: 0.001
  14. CCDC22: a novel candidate gene for syndromic X-linked intellectual disability. Mol Psychiatry. 2012 Jan; 17(1):4-7.
    View in: PubMed
    Score: 0.001
  15. Human-specific transcriptional regulation of CNS development genes by FOXP2. Nature. 2009 Nov 12; 462(7270):213-7.
    View in: PubMed
    Score: 0.001
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.

Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.