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Shuning He, Ph.D.

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Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Durbin AD, Zimmerman MW, Dharia NV, Abraham BJ, Iniguez AB, Weichert-Leahey N, He S, Krill-Burger JM, Root DE, Vazquez F, Tsherniak A, Hahn WC, Golub TR, Young RA, Look AT, Stegmaier K. Selective gene dependencies in MYCN-amplified neuroblastoma include the core transcriptional regulatory circuitry. Nat Genet. 2018 09; 50(9):1240-1246. PMID: 30127528.
    Citations: 1     Fields:    
  2. Li Z, He S, Look AT. The MCL1-specific inhibitor S63845 acts synergistically with venetoclax/ABT-199 to induce apoptosis in T-cell acute lymphoblastic leukemia cells. Leukemia. 2019 01; 33(1):262-266. PMID: 30008477.
    Citations:    Fields:    
  3. Mansour MR, He S, Li Z, Lobbardi R, Abraham BJ, Hug C, Rahman S, Leon TE, Kuang YY, Zimmerman MW, Blonquist T, Gjini E, Gutierrez A, Tang Q, Garcia-Perez L, Pike-Overzet K, Anders L, Berezovskaya A, Zhou Y, Zon LI, Neuberg D, Fielding AK, Staal FJT, Langenau DM, Sanda T, Young RA, Look AT. JDP2: An oncogenic bZIP transcription factor in T cell acute lymphoblastic leukemia. J Exp Med. 2018 07 02; 215(7):1929-1945. PMID: 29941549.
    Citations:    Fields:    
  4. Zimmerman MW, Liu Y, He S, Durbin AD, Abraham BJ, Easton J, Shao Y, Xu B, Zhu S, Zhang X, Li Z, Weichert-Leahey N, Young RA, Zhang J, Look AT. MYC Drives a Subset of High-Risk Pediatric Neuroblastomas and Is Activated through Mechanisms Including Enhancer Hijacking and Focal Enhancer Amplification. Cancer Discov. 2018 03; 8(3):320-335. PMID: 29284669.
    Citations: 2     Fields:    
  5. Zhu S, Zhang X, Weichert-Leahey N, Dong Z, Zhang C, Lopez G, Tao T, He S, Wood AC, Oldridge D, Ung CY, van Ree JH, Khan A, Salazar BM, Lummertz da Rocha E, Zimmerman MW, Guo F, Cao H, Hou X, Weroha SJ, Perez-Atayde AR, Neuberg DS, Meves A, McNiven MA, van Deursen JM, Li H, Maris JM, Look AT. LMO1 Synergizes with MYCN to Promote Neuroblastoma Initiation and Metastasis. Cancer Cell. 2017 09 11; 32(3):310-323.e5. PMID: 28867147.
    Citations: 7     Fields:    Translation:HumansAnimalsCells
  6. Zhang X, Dong Z, Zhang C, Ung CY, He S, Tao T, Oliveira AM, Meves A, Ji B, Look AT, Li H, Neel BG, Zhu S. Critical Role for GAB2 in Neuroblastoma Pathogenesis through the Promotion of SHP2/MYCN Cooperation. Cell Rep. 2017 03 21; 18(12):2932-2942. PMID: 28329685.
    Citations:    Fields:    Translation:HumansAnimalsCells
  7. Ki DH, He S, Rodig S, Look AT. Overexpression of PDGFRA cooperates with loss of NF1 and p53 to accelerate the molecular pathogenesis of malignant peripheral nerve sheath tumors. Oncogene. 2017 02 23; 36(8):1058-1068. PMID: 27477693.
    Citations: 5     Fields:    Translation:HumansAnimalsCells
  8. He S, Mansour MR, Zimmerman MW, Ki DH, Layden HM, Akahane K, Gjini E, de Groh ED, Perez-Atayde AR, Zhu S, Epstein JA, Look AT. Synergy between loss of NF1 and overexpression of MYCN in neuroblastoma is mediated by the GAP-related domain. Elife. 2016 04 27; 5. PMID: 27130733.
    Citations: 5     Fields:    Translation:AnimalsCells
  9. Tang Q, Moore JC, Ignatius MS, Tenente IM, Hayes MN, Garcia EG, Torres Yordán N, Bourque C, He S, Blackburn JS, Look AT, Houvras Y, Langenau DM. Imaging tumour cell heterogeneity following cell transplantation into optically clear immune-deficient zebrafish. Nat Commun. 2016 Jan 21; 7:10358. PMID: 26790525.
    Citations: 15     Fields:    Translation:HumansAnimals
  10. Durbin AD, Ki DH, He S, Look AT. Malignant Peripheral Nerve Sheath Tumors. Adv Exp Med Biol. 2016; 916:495-530. PMID: 27165368.
    Citations: 2     Fields:    Translation:Animals
  11. Tulotta C, He S, Chen L, Groenewoud A, van der Ent W, Meijer AH, Spaink HP, Snaar-Jagalska BE. Imaging of Human Cancer Cell Proliferation, Invasion, and Micrometastasis in a Zebrafish Xenogeneic Engraftment Model. Methods Mol Biol. 2016; 1451:155-69. PMID: 27464807.
    Citations: 3     Fields:    Translation:HumansAnimalsCells
  12. Gjini E, Mansour MR, Sander JD, Moritz N, Nguyen AT, Kesarsing M, Gans E, He S, Chen S, Ko M, Kuang YY, Yang S, Zhou Y, Rodig S, Zon LI, Joung JK, Rao A, Look AT. A zebrafish model of myelodysplastic syndrome produced through tet2 genomic editing. Mol Cell Biol. 2015 Mar; 35(5):789-804. PMID: 25512612.
    Citations: 15     Fields:    Translation:HumansAnimalsCells
  13. Ghotra VP, He S, van der Horst G, Nijhoff S, de Bont H, Lekkerkerker A, Janssen R, Jenster G, van Leenders GJ, Hoogland AM, Verhoef EI, Baranski Z, Xiong J, van de Water B, van der Pluijm G, Snaar-Jagalska BE, Danen EH. SYK is a candidate kinase target for the treatment of advanced prostate cancer. Cancer Res. 2015 Jan 01; 75(1):230-40. PMID: 25388286.
    Citations: 16     Fields:    Translation:HumansAnimalsCells
  14. Truong HH, Xiong J, Ghotra VP, Nirmala E, Haazen L, Le Dévédec SE, Balcioglu HE, He S, Snaar-Jagalska BE, Vreugdenhil E, Meerman JH, van de Water B, Danen EH. ß1 integrin inhibition elicits a prometastatic switch through the TGFß-miR-200-ZEB network in E-cadherin-positive triple-negative breast cancer. Sci Signal. 2014 Feb 11; 7(312):ra15. PMID: 24518294.
    Citations: 24     Fields:    Translation:HumansAnimalsCells
  15. Drabsch Y, He S, Zhang L, Snaar-Jagalska BE, ten Dijke P. Transforming growth factor-ß signalling controls human breast cancer metastasis in a zebrafish xenograft model. Breast Cancer Res. 2013 Nov 07; 15(6):R106. PMID: 24196484.
    Citations: 23     Fields:    Translation:HumansAnimalsCells
  16. Shin J, Padmanabhan A, de Groh ED, Lee JS, Haidar S, Dahlberg S, Guo F, He S, Wolman MA, Granato M, Lawson ND, Wolfe SA, Kim SH, Solnica-Krezel L, Kanki JP, Ligon KL, Epstein JA, Look AT. Zebrafish neurofibromatosis type 1 genes have redundant functions in tumorigenesis and embryonic development. Dis Model Mech. 2012 Nov; 5(6):881-94. PMID: 22773753.
    Citations: 16     Fields:    Translation:AnimalsCells
  17. He S, Lamers GE, Beenakker JW, Cui C, Ghotra VP, Danen EH, Meijer AH, Spaink HP, Snaar-Jagalska BE. Neutrophil-mediated experimental metastasis is enhanced by VEGFR inhibition in a zebrafish xenograft model. J Pathol. 2012 Aug; 227(4):431-45. PMID: 22374800.
    Citations: 46     Fields:    Translation:HumansAnimalsCells
  18. Ghotra VP, He S, de Bont H, van der Ent W, Spaink HP, van de Water B, Snaar-Jagalska BE, Danen EH. Automated whole animal bio-imaging assay for human cancer dissemination. PLoS One. 2012; 7(2):e31281. PMID: 22347456.
    Citations: 21     Fields:    Translation:HumansAnimalsCells
  19. Camus S, Quevedo C, Menéndez S, Paramonov I, Stouten PF, Janssen RA, Rueb S, He S, Snaar-Jagalska BE, Laricchia-Robbio L, Izpisua Belmonte JC. Identification of phosphorylase kinase as a novel therapeutic target through high-throughput screening for anti-angiogenesis compounds in zebrafish. Oncogene. 2012 Sep 27; 31(39):4333-42. PMID: 22179836.
    Citations: 11     Fields:    Translation:HumansAnimalsCells
  20. He S, Krens SG, Zhan H, Gong Z, Hogendoorn PC, Spaink HP, Snaar-Jagalska BE. A ?Raf1-ER-inducible oncogenic zebrafish liver cell model identifies hepatocellular carcinoma signatures. J Pathol. 2011 Sep; 225(1):19-28. PMID: 21744342.
    Citations: 5     Fields:    Translation:HumansAnimalsCells
  21. Kabli S, He S, Spaink HP, Hurlstone A, Jagalska ES, De Groot HJ, Alia A. In vivo magnetic resonance imaging to detect malignant melanoma in adult zebrafish. Zebrafish. 2010 Jun; 7(2):143-8. PMID: 20515295.
    Citations: 5     Fields:    Translation:Animals
  22. Krens SF, He S, Lamers GE, Meijer AH, Bakkers J, Schmidt T, Spaink HP, Snaar-Jagalska BE. Distinct functions for ERK1 and ERK2 in cell migration processes during zebrafish gastrulation. Dev Biol. 2008 Jul 15; 319(2):370-83. PMID: 18514184.
    Citations: 25     Fields:    Translation:AnimalsCells
  23. Krens SF, Corredor-Adámez M, He S, Snaar-Jagalska BE, Spaink HP. ERK1 and ERK2 MAPK are key regulators of distinct gene sets in zebrafish embryogenesis. BMC Genomics. 2008 Apr 28; 9:196. PMID: 18442396.
    Citations: 15     Fields:    Translation:AnimalsCells
  24. Krens SF, He S, Spaink HP, Snaar-Jagalska BE. Characterization and expression patterns of the MAPK family in zebrafish. Gene Expr Patterns. 2006 Oct; 6(8):1019-26. PMID: 16774848.
    Citations: 20     Fields:    Translation:AnimalsCells
  25. He S, Salas-Vidal E, Rueb S, Krens SF, Meijer AH, Snaar-Jagalska BE, Spaink HP. Genetic and transcriptome characterization of model zebrafish cell lines. Zebrafish. 2006; 3(4):441-53. PMID: 18377224.
    Citations: 11     Fields:    
  26. Meijer AH, Gabby Krens SF, Medina Rodriguez IA, He S, Bitter W, Ewa Snaar-Jagalska B, Spaink HP. Expression analysis of the Toll-like receptor and TIR domain adaptor families of zebrafish. Mol Immunol. 2004 Jan; 40(11):773-83. PMID: 14687934.
    Citations: 80     Fields:    Translation:AnimalsCells
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.