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Kai Bao, Ph.D.

Concepts

This page shows the publications Kai Bao has written about Antineoplastic Agents.
Connection Strength

0.584
  1. Design, synthesis and bio-evaluation of novel 2-aryl-4-(3,4,5-trimethoxy-benzoyl)-5-substituted-1,2,3-triazoles as the tubulin polymerization inhibitors. Eur J Med Chem. 2020 Jan 15; 186:111846.
    View in: PubMed
    Score: 0.152
  2. Renal Clearable Theranostic Nanoplatforms for Gastrointestinal Stromal Tumors. Adv Mater. 2020 Feb; 32(6):e1905899.
    View in: PubMed
    Score: 0.038
  3. Activated carbon/Br√łnsted acid-promoted aerobic benzylic oxidation under "on-water" condition: Green and efficient synthesis of 3-benzoylquinoxalinones as potent tubulin inhibitors. Eur J Med Chem. 2020 Jan 15; 186:111894.
    View in: PubMed
    Score: 0.038
  4. Design, synthesis and biological evaluation of 3,4-diaryl-1,2,5-oxadiazole-2/5-oxides as highly potent inhibitors of tubulin polymerization. Eur J Med Chem. 2019 Sep 15; 178:287-296.
    View in: PubMed
    Score: 0.037
  5. Synthesis and bioevaluation of diarylpyrazoles as antiproliferative agents. Eur J Med Chem. 2019 Jun 01; 171:1-10.
    View in: PubMed
    Score: 0.036
  6. 3,5-Diaryl-1H-pyrazolo[3,4-b]pyridines as potent tubulin polymerization inhibitors: Rational design, synthesis and biological evaluation. Eur J Med Chem. 2019 Apr 15; 168:426-435.
    View in: PubMed
    Score: 0.036
  7. Synthesis and biological evaluation of (1-aryl-1H-pyrazol-4-yl) (3,4,5-trimethoxyphenyl)methanone derivatives as tubulin inhibitors. Eur J Med Chem. 2018 Aug 05; 156:137-147.
    View in: PubMed
    Score: 0.035
  8. Design, synthesis and bioevaluation of antitubulin agents carrying diaryl-5,5-fused-heterocycle scaffold. Eur J Med Chem. 2017 Oct 20; 139:242-249.
    View in: PubMed
    Score: 0.032
  9. Synthesis and bioevaluation of N,4-diaryl-1,3-thiazole-2-amines as tubulin inhibitors with potent antiproliferative activity. PLoS One. 2017; 12(3):e0174006.
    View in: PubMed
    Score: 0.032
  10. Development of Novel Erythromycin Derivatives with Inhibitory Activity against Proliferation of Tumor Cells. PLoS One. 2016; 11(7):e0159503.
    View in: PubMed
    Score: 0.030
  11. Ultrasound-promoted two-step synthesis of 3-arylselenylindoles and 3-arylthioindoles as novel combretastatin A-4 analogues. Sci Rep. 2016 Apr 05; 6:23986.
    View in: PubMed
    Score: 0.030
  12. Synthesis and Biological Evaluations of 1,2-Diaryl Pyrroles as Analogues of Combretastatin A-4. Chem Biol Drug Des. 2015 Dec; 86(6):1541-7.
    View in: PubMed
    Score: 0.029
  13. Synthesis and evaluation of benzimidazole carbamates bearing indole moieties for antiproliferative and antitubulin activities. Eur J Med Chem. 2014 Nov 24; 87:306-15.
    View in: PubMed
    Score: 0.027
  14. Synthesis and antiproliferative in-vitro activity of natural flavans and related compounds. Arch Pharm (Weinheim). 2007 Dec; 340(12):650-5.
    View in: PubMed
    Score: 0.017
  15. Design, synthesis and structure-activity relationship of 3,6-diaryl-7H-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazines as novel tubulin inhibitors. Sci Rep. 2017 09 20; 7(1):11997.
    View in: PubMed
    Score: 0.008
  16. 4,5-Diaryl-3H-1,2-dithiole-3-thiones and related compounds as combretastatin A-4/oltipraz hybrids: Synthesis, molecular modelling and evaluation as antiproliferative agents and inhibitors of tubulin. Eur J Med Chem. 2016 Oct 21; 122:520-529.
    View in: PubMed
    Score: 0.008
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.

Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.