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Jay Dr Luther, M.D.

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Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Borren NZ, Tan W, Jess AT, Li PM, Garber JJ, Luther J, Colizzo FP, Khalili H, Ananthakrishnan AN. Assessment of Body Weight Changes in Patients with Inflammatory Bowel Diseases Initiating Biologic Therapy: A Prospective Cohort Study. Dig Dis Sci. 2020 12; 65(12):3672-3678. PMID: 32617768.
    Citations: 1     Fields:    Translation:Humans
  2. Luther J, Khan S, Gala MK, Kedrin D, Sridharan G, Goodman RP, Garber JJ, Masia R, Diagacomo E, Adams D, King KR, Piaker S, Reinecker HC, Yarmush ML, Argemi J, Bataller R, Dienstag JL, Chung RT, Patel SJ. Hepatic gap junctions amplify alcohol liver injury by propagating cGAS-mediated IRF3 activation. Proc Natl Acad Sci U S A. 2020 05 26; 117(21):11667-11673. PMID: 32393626.
    Citations: 22     Fields:    Translation:HumansAnimalsCells
  3. Borren NZ, Plichta D, Joshi AD, Bonilla G, Peng V, Colizzo FP, Luther J, Khalili H, Garber JJ, Janneke van der Woude C, Sadreyev R, Vlamakis H, Xavier RJ, Ananthakrishnan AN. Alterations in Fecal Microbiomes and Serum Metabolomes of Fatigued Patients With Quiescent Inflammatory Bowel Diseases. Clin Gastroenterol Hepatol. 2021 03; 19(3):519-527.e5. PMID: 32184182.
    Citations: 9     Fields:    Translation:HumansCells
  4. Borren NZ, Tan W, Colizzo FP, Luther J, Garber JJ, Khalili H, van Der Woude CJ, Ananthakrishnan AN. Longitudinal Trajectory of Fatigue With Initiation of Biologic Therapy in Inflammatory Bowel Diseases: A Prospective Cohort Study. J Crohns Colitis. 2020 Mar 13; 14(3):309-315. PMID: 31504365.
    Citations: 7     Fields:    Translation:Humans
  5. Luther J, Dave M. Rising Inflammatory Bowel Disease Prevalence Highlights the Need for Effective, Cost-Effective Therapies. Inflamm Bowel Dis. 2020 03 04; 26(4):626-627. PMID: 31854449.
    Citations: 2     Fields:    Translation:Humans
  6. Sheriff MZ, Mansoor E, Luther J, Ananthakrishnan AN, Abou Saleh M, Ho E, Briggs FBS, Dave M. Opportunistic Infections Are More Prevalent in Crohn's Disease and Ulcerative Colitis: A Large Population-Based Study. Inflamm Bowel Dis. 2020 01 06; 26(2):291-300. PMID: 31314891.
    Citations: 5     Fields:    Translation:Humans
  7. Bloom PP, Rodriguez-Lopez J, Witkin AS, Al-Samkari H, Kuter DJ, Mojtahed A, Luther J. Ammonia Predicts Hepatic Involvement and Pulmonary Hypertension in Patients With Hereditary Hemorrhagic Telangiectasia. Clin Transl Gastroenterol. 2020 01; 11(1):e00118. PMID: 31977452; PMCID: PMC7056052.
    Citations: 1     Fields:    Translation:Humans
  8. Borren NZ, Luther J, Colizzo FP, Garber JG, Khalili H, Ananthakrishnan AN. Low-dose Methotrexate has Similar Outcomes to High-dose Methotrexate in Combination with Anti-TNF Therapy in Inflammatory Bowel Diseases. J Crohns Colitis. 2019 Aug 14; 13(8):990-995. PMID: 30888405.
    Citations: 2     Fields:    Translation:Humans
  9. Borren NZ, Khalili H, Luther J, Colizzo FP, Garber JJ, Ananthakrishnan AN. Second-Look Endoscopy in Hospitalized Severe Ulcerative Colitis: A Retrospective Cohort Study. Inflamm Bowel Dis. 2019 03 14; 25(4):750-755. PMID: 30204864; PMCID: PMC6765053.
    Citations: 4     Fields:    Translation:Humans
  10. Luther J, Gala MK, Borren N, Masia R, Goodman RP, Moeller IH, DiGiacomo E, Ehrlich A, Warren A, Yarmush ML, Ananthakrishnan A, Corey K, Kaplan LM, Bhatia S, Chung RT, Patel SJ. Hepatic connexin 32 associates with nonalcoholic fatty liver disease severity. Hepatol Commun. 2018 Jul; 2(7):786-797. PMID: 30202815; PMCID: PMC6123534.
    Citations: 6     Fields:    
  11. Vedamurthy A, Xu L, Luther J, Colizzo F, Garber JJ, Khalili H, Ananthakrishnan AN. Long-Term Outcomes of Immunosuppression-Naïve Steroid Responders Following Hospitalization for Ulcerative Colitis. Dig Dis Sci. 2018 10; 63(10):2740-2746. PMID: 29951797; PMCID: PMC6139272.
    Citations: 5     Fields:    Translation:Humans
  12. Nalagatla N, Falloon K, Tran G, Borren NZ, Avalos D, Luther J, Colizzo F, Garber J, Khalili H, Melia J, Bohm M, Ananthakrishnan AN. Effect of Accelerated Infliximab Induction on Short- and Long-term Outcomes of Acute Severe Ulcerative Colitis: A Retrospective Multicenter Study and Meta-analysis. Clin Gastroenterol Hepatol. 2019 02; 17(3):502-509.e1. PMID: 29944926; PMCID: PMC6309670.
    Citations: 21     Fields:    Translation:Humans
  13. Luther J, Dienstag JL. Reply to: "Primed for the spotlight: Transplantation for alcohol-associated liver disease". J Hepatol. 2018 07; 69(1):255. PMID: 29650334.
    Citations:    Fields:    Translation:Humans
  14. Luther J, Dienstag JL. Reply to: "Assessment of the risk of alcohol relapse following liver transplantation for alcoholic hepatitis using a meta-analysis approach". J Hepatol. 2018 06; 68(6):1323. PMID: 29505846.
    Citations:    Fields:    Translation:Humans
  15. Luther J, Dienstag JL. Hardened Liver Due to Fibrolamellar Hepatocellular Carcinoma. Clin Gastroenterol Hepatol. 2019 01; 17(1):A27. PMID: 29505903.
    Citations:    Fields:    Translation:Humans
  16. Luther J, Gala M, Patel SJ, Dave M, Borren N, Xavier RJ, Ananthakrishnan AN. Loss of Response to Anti-Tumor Necrosis Factor Alpha Therapy in Crohn's Disease Is Not Associated with Emergence of Novel Inflammatory Pathways. Dig Dis Sci. 2018 03; 63(3):738-745. PMID: 29372477; PMCID: PMC6152907.
    Citations: 8     Fields:    Translation:Humans
  17. Kubiliun M, Patel SJ, Hur C, Dienstag JL, Luther J. Early liver transplantation for alcoholic hepatitis: Ready for primetime? J Hepatol. 2018 03; 68(3):380-382. PMID: 29175244.
    Citations: 2     Fields:    Translation:Humans
  18. Masia R, McCarty WJ, Lahmann C, Luther J, Chung RT, Yarmush ML, Yellen G. Live cell imaging of cytosolic NADH/NAD+ ratio in hepatocytes and liver slices. Am J Physiol Gastrointest Liver Physiol. 2018 01 01; 314(1):G97-G108. PMID: 29025729; PMCID: PMC5866369.
    Citations: 4     Fields:    Translation:HumansAnimalsCells
  19. Luther J, Pierce VM. Case 21-2016: A Man in an Unresponsive State. N Engl J Med. 2016 10 27; 375(17):1697. PMID: 27783904.
    Citations:    Fields:    Translation:Humans
  20. Salloum S, Holmes JA, Jindal R, Bale SS, Brisac C, Alatrakchi N, Lidofsky A, Kruger AJ, Fusco DN, Luther J, Schaefer EA, Lin W, Yarmush ML, Chung RT. Exposure to human immunodeficiency virus/hepatitis C virus in hepatic and stellate cell lines reveals cooperative profibrotic transcriptional activation between viruses and cell types. Hepatology. 2016 12; 64(6):1951-1968. PMID: 27531241.
    Citations: 22     Fields:    Translation:HumansCells
  21. Fenves AZ, Schaefer PW, Luther J, Pierce VM. CASE RECORDS of the MASSACHUSETTS GENERAL HOSPITAL. Case 21-2016. A 32-Year-Old Man in an Unresponsive State. N Engl J Med. 2016 Jul 14; 375(2):163-71. PMID: 27410926.
    Citations:    Fields:    Translation:Humans
  22. Patel SJ, Luther J, Bohr S, Iracheta-Vellve A, Li M, King KR, Chung RT, Yarmush ML. A Novel Resolvin-Based Strategy for Limiting Acetaminophen Hepatotoxicity. Clin Transl Gastroenterol. 2016 Mar 17; 7:e153. PMID: 26986653.
    Citations: 13     Fields:    
  23. Dave M, Mehta K, Luther J, Baruah A, Dietz AB, Faubion WA. Mesenchymal Stem Cell Therapy for Inflammatory Bowel Disease: A Systematic Review and Meta-analysis. Inflamm Bowel Dis. 2015 Nov; 21(11):2696-707. PMID: 26230863; PMCID: PMC4615553.
    Citations: 42     Fields:    Translation:HumansAnimals
  24. Luther J, Garber JJ, Khalili H, Dave M, Bale SS, Jindal R, Motola DL, Luther S, Bohr S, Jeoung SW, Deshpande V, Singh G, Turner JR, Yarmush ML, Chung RT, Patel SJ. Hepatic Injury in Nonalcoholic Steatohepatitis Contributes to Altered Intestinal Permeability. Cell Mol Gastroenterol Hepatol. 2015 Mar; 1(2):222-232. PMID: 26405687.
    Citations: 99     Fields:    
  25. Jilg N, Lin W, Hong J, Schaefer EA, Wolski D, Meixong J, Goto K, Brisac C, Chusri P, Fusco DN, Chevaliez S, Luther J, Kumthip K, Urban TJ, Peng LF, Lauer GM, Chung RT. Kinetic differences in the induction of interferon stimulated genes by interferon-a and interleukin 28B are altered by infection with hepatitis C virus. Hepatology. 2014 Apr; 59(4):1250-61. PMID: 23913866.
    Citations: 60     Fields:    Translation:HumansCells
  26. Berndt BE, Zhang M, Owyang SY, Cole TS, Wang TW, Luther J, Veniaminova NA, Merchant JL, Chen CC, Huffnagle GB, Kao JY. Butyrate increases IL-23 production by stimulated dendritic cells. Am J Physiol Gastrointest Liver Physiol. 2012 Dec 15; 303(12):G1384-92. PMID: 23086919.
    Citations: 54     Fields:    Translation:AnimalsCells
  27. Luther J, Faje AJ, Al-Hawary M, Kao JY. Anaplastic lymphoma masquerading as sclerosing mesenteritis: a case report. J Gastrointest Cancer. 2012 Jun; 43(2):364-6. PMID: 21360272.
    Citations: 3     Fields:    Translation:Humans
  28. Cole TS, Zhang M, Standiford TJ, Newstead M, Luther J, Zhang J, Chen CC, Kao JY. IRAK-M modulates expression of IL-10 and cell surface markers CD80 and MHC II after bacterial re-stimulation of tolerized dendritic cells. Immunol Lett. 2012 May 30; 144(1-2):49-59. PMID: 22472665.
    Citations: 9     Fields:    Translation:AnimalsCells
  29. Owyang SY, Luther J, Owyang CC, Zhang M, Kao JY. Helicobacter pylori DNA's anti-inflammatory effect on experimental colitis. Gut Microbes. 2012 Mar-Apr; 3(2):168-71. PMID: 22356863.
    Citations: 20     Fields:    Translation:HumansAnimalsCells
  30. Owyang SY, Luther J, Kao JY. Helicobacter pylori: beneficial for most? Expert Rev Gastroenterol Hepatol. 2011 Dec; 5(6):649-51. PMID: 22017690.
    Citations: 4     Fields:    Translation:HumansCells
  31. Kaur N, Chen CC, Luther J, Kao JY. Intestinal dysbiosis in inflammatory bowel disease. Gut Microbes. 2011 Jul-Aug; 2(4):211-6. PMID: 21983063.
    Citations: 46     Fields:    Translation:HumansCells
  32. Luther J, Owyang SY, Takeuchi T, Cole TS, Zhang M, Liu M, Erb-Downward J, Rubenstein JH, Chen CC, Pierzchala AV, Paul JA, Kao JY. Helicobacter pylori DNA decreases pro-inflammatory cytokine production by dendritic cells and attenuates dextran sodium sulphate-induced colitis. Gut. 2011 Nov; 60(11):1479-86. PMID: 21471567; PMCID: PMC3466055.
    Citations: 50     Fields:    Translation:HumansAnimalsCells
  33. Luther J, Chey WD, Saad RJ. A clinician's guide to salvage therapy for persistent Helicobacter pylori infection. Hosp Pract (1995). 2011 Feb; 39(1):133-40. PMID: 21441768.
    Citations: 3     Fields:    Translation:HumansCells
  34. Higgins PD, Johnson LA, Luther J, Zhang M, Sauder KL, Blanco LP, Kao JY. Prior Helicobacter pylori infection ameliorates Salmonella typhimurium-induced colitis: mucosal crosstalk between stomach and distal intestine. Inflamm Bowel Dis. 2011 Jun; 17(6):1398-408. PMID: 21560200.
    Citations: 47     Fields:    Translation:HumansAnimalsCells
  35. Zhang M, Liu M, Luther J, Kao JY. Helicobacter pylori directs tolerogenic programming of dendritic cells. Gut Microbes. 2010 Sep; 1(5):325-329. PMID: 21327041.
    Citations: 20     Fields:    
  36. Luther J, Dave M, Higgins PD, Kao JY. Association between Helicobacter pylori infection and inflammatory bowel disease: a meta-analysis and systematic review of the literature. Inflamm Bowel Dis. 2010 Jun; 16(6):1077-84. PMID: 19760778.
    Citations: 110     Fields:    Translation:HumansAnimalsCells
  37. Luther J, Kao JY. Considering global vaccination against Helicobacter pylori. South Med J. 2010 Mar; 103(3):185-6. PMID: 20134368.
    Citations: 3     Fields:    Translation:HumansCells
  38. Luther J, Chey WD. ACP Journal Club. Psyllium increased symptom relief in patients with the irritable bowel syndrome more than bran or placebo. Ann Intern Med. 2010 Jan 19; 152(2):JC1-11. PMID: 20083814.
    Citations: 2     Fields:    
  39. Kao JY, Zhang M, Miller MJ, Mills JC, Wang B, Liu M, Eaton KA, Zou W, Berndt BE, Cole TS, Takeuchi T, Owyang SY, Luther J. Helicobacter pylori immune escape is mediated by dendritic cell-induced Treg skewing and Th17 suppression in mice. Gastroenterology. 2010 Mar; 138(3):1046-54. PMID: 19931266; PMCID: PMC2831148.
    Citations: 136     Fields:    Translation:AnimalsCells
  40. Luther J, Higgins PD, Schoenfeld PS, Moayyedi P, Vakil N, Chey WD. Empiric quadruple vs. triple therapy for primary treatment of Helicobacter pylori infection: Systematic review and meta-analysis of efficacy and tolerability. Am J Gastroenterol. 2010 Jan; 105(1):65-73. PMID: 19755966.
    Citations: 58     Fields:    Translation:HumansCells
  41. Luther J, Chey WD. Sequential therapy for Helicobacter pylori: a two for one deal that's worth the extra effort? Gastroenterology. 2009 Feb; 136(2):720-2. PMID: 19109960.
    Citations: 2     Fields:    
  42. Luther J, Glesby MJ. Dermatologic adverse effects of antiretroviral therapy: recognition and management. Am J Clin Dermatol. 2007; 8(4):221-33. PMID: 17645377.
    Citations: 2     Fields:    Translation:Humans
  43. Spadaro JA, Horton JA, Margulies BS, Luther J, Strauss JA, Farnum CE, Damron TA. Radioprotectant combinations spare radiation-induced damage to the physis more than fractionation alone. Int J Radiat Biol. 2005 Oct; 81(10):759-65. PMID: 16449083.
    Citations: 5     Fields:    Translation:AnimalsPHPublic Health
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.