p120 GTPase Activating Protein

"p120 GTPase Activating Protein" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A 120-kDa RAS GTPase-activating protein that binds to tyrosine phosphoproteins through its SH2 domains. The 100-kDa RNA-splicing variant (p100 GAP protein) is expressed in placenta.

Descriptor ID

D020729

MeSH Number(s)

D12.644.360.325.150.500.500

D12.776.402.150.500.500

D12.776.476.325.150.500.500

Concept/Terms

p120 GTPase Activating Protein

p100-GAP Protein

Below are MeSH descriptors whose meaning is more general than "p120 GTPase Activating Protein".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Peptides [D12.644]
Intracellular Signaling Peptides and Proteins [D12.644.360]
GTP-Binding Protein Regulators [D12.644.360.325]
GTPase-Activating Proteins [D12.644.360.325.150]
ras GTPase-Activating Proteins [D12.644.360.325.150.500]
p120 GTPase Activating Protein [D12.644.360.325.150.500.500]
Proteins [D12.776]
GTP-Binding Protein Regulators [D12.776.402]
GTPase-Activating Proteins [D12.776.402.150]
ras GTPase-Activating Proteins [D12.776.402.150.500]
p120 GTPase Activating Protein [D12.776.402.150.500.500]
Intracellular Signaling Peptides and Proteins [D12.776.476]
GTP-Binding Protein Regulators [D12.776.476.325]
GTPase-Activating Proteins [D12.776.476.325.150]
ras GTPase-Activating Proteins [D12.776.476.325.150.500]
p120 GTPase Activating Protein [D12.776.476.325.150.500.500]

Below are MeSH descriptors whose meaning is related to "p120 GTPase Activating Protein".

Below are MeSH descriptors whose meaning is more specific than "p120 GTPase Activating Protein".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "p120 GTPase Activating Protein" by people in Harvard Catalyst Profiles by year, and whether "p120 GTPase Activating Protein" was a major or minor topic of these publication.

Below are the most recent publications written about "p120 GTPase Activating Protein" by people in Profiles.

Mutation of key signaling regulators of cerebrovascular development in vein of Galen malformations. Nat Commun. 2023 11 17; 14(1):7452.

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Spectrum of lymphatic anomalies in patients with RASA1-related CM-AVM. Pediatr Dermatol. 2023 Nov-Dec; 40(6):1028-1034.

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Parkes Weber syndrome with lymphedema caused by a somatic KRAS variant. Cold Spring Harb Mol Case Stud. 2021 12; 7(6).

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Clinical and molecular characterization of patients with hereditary hemorrhagic telangiectasia: Experience from an HHT Center of Excellence. Am J Med Genet A. 2021 07; 185(7):1981-1990.

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Atypical capillary malformations with subsequent diplegia: A difficult case of capillary malformation-arteriovenous malformation syndrome. Pediatr Dermatol. 2020 Jan; 37(1):162-164.

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EphrinB2-EphB4-RASA1 Signaling in Human Cerebrovascular Development and Disease. Trends Mol Med. 2019 04; 25(4):265-286.

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Expanding the clinical and molecular findings in RASA1 capillary malformation-arteriovenous malformation. Eur J Hum Genet. 2018 10; 26(10):1521-1536.

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RASA1/NF1-Mutant Lung Cancer: Racing to the Clinic? Clin Cancer Res. 2018 03 15; 24(6):1243-1245.

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Germline Loss-of-Function Mutations in EPHB4 Cause a Second Form of Capillary Malformation-Arteriovenous Malformation (CM-AVM2) Deregulating RAS-MAPK Signaling. Circulation. 2017 Sep 12; 136(11):1037-1048.

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Genetic Variants Associated with Port-Wine Stains. PLoS One. 2015; 10(7):e0133158.

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