Harvard Catalyst Profiles

The original member of the family of endothelial cell growth factors referred to as VASCULAR ENDOTHELIAL GROWTH FACTORS. Vascular endothelial growth factor-A was originally isolated from tumor cells and referred to as "tumor angiogenesis factor" and "vascular permeability factor". Although expressed at high levels in certain tumor-derived cells it is produced by a wide variety of cell types. In addition to stimulating vascular growth and vascular permeability it may play a role in stimulating VASODILATION via NITRIC OXIDE-dependent pathways. Alternative splicing of the mRNA for vascular endothelial growth factor A results in several isoforms of the protein being produced.

Below are MeSH descriptors whose meaning is more general than "Vascular Endothelial Growth Factor A".

Below are MeSH descriptors whose meaning is related to "Vascular Endothelial Growth Factor A".

Below are MeSH descriptors whose meaning is more specific than "Vascular Endothelial Growth Factor A".