"Uracil-DNA Glycosidase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An enzyme that catalyzes the HYDROLYSIS of the N-glycosidic bond between sugar phosphate backbone and URACIL residue during DNA synthesis.
Concept/Terms
Uracil-DNA Glycosidase- Uracil-DNA Glycosidase
- Glycosidase, Uracil-DNA
- Uracil DNA Glycosidase
- Ura-DNA Glycosidase
- Glycosidase, Ura-DNA
- Ura DNA Glycosidase
- Uracil-DNA Glycosylase
- Glycosylase, Uracil-DNA
- Uracil DNA Glycosylase
- DNA Glycosylase, Uracil
- Glycosylase, Uracil DNA
- Uracil N-Glycosidase
- N-Glycosidase, Uracil
- Uracil N Glycosidase
- Uracil N-Glycosylase
- N-Glycosylase, Uracil
- Uracil N Glycosylase
- Ung DNA Glycosylase
- DNA Glycosylase, Ung
- Glycosylase, Ung DNA
- Ura-DNA Glycosylase
- Glycosylase, Ura-DNA
- Ura DNA Glycosylase
Below are MeSH descriptors whose meaning is more general than "Uracil-DNA Glycosidase".
Below are MeSH descriptors whose meaning is more specific than "Uracil-DNA Glycosidase".
This graph shows the total number of publications written about "Uracil-DNA Glycosidase" by people in Harvard Catalyst Profiles by year, and whether "Uracil-DNA Glycosidase" was a major or minor topic of these publication.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1999 | 0 | 1 | 1 |
| 2000 | 0 | 1 | 1 |
| 2001 | 0 | 3 | 3 |
| 2003 | 0 | 2 | 2 |
| 2004 | 0 | 1 | 1 |
| 2010 | 1 | 0 | 1 |
| 2011 | 0 | 1 | 1 |
| 2012 | 1 | 0 | 1 |
| 2013 | 2 | 0 | 2 |
| 2014 | 4 | 0 | 4 |
| 2015 | 1 | 0 | 1 |
| 2016 | 1 | 0 | 1 |
| 2018 | 1 | 1 | 2 |
| 2019 | 0 | 1 | 1 |
| 2021 | 1 | 0 | 1 |
| 2022 | 0 | 1 | 1 |
Below are the most recent publications written about "Uracil-DNA Glycosidase" by people in Profiles.
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Mechanisms of APOBEC3 mutagenesis in human cancer cells. Nature. 2022 07; 607(7920):799-807.
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An effective human uracil-DNA glycosylase inhibitor targets the open pre-catalytic active site conformation. Prog Biophys Mol Biol. 2021 08; 163:143-159.
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Classification of human Herpesviridae proteins using Domain-architecture Aware Inference of Orthologs (DAIO). Virology. 2019 03; 529:29-42.
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N-terminal domain of human uracil DNA glycosylase (hUNG2) promotes targeting to uracil sites adjacent to ssDNA-dsDNA junctions. Nucleic Acids Res. 2018 08 21; 46(14):7169-7178.
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Site-Specific Protein Labeling with N-Hydroxysuccinimide-Esters and the Analysis of Ubiquitin Ligase Mechanisms. J Am Chem Soc. 2018 08 01; 140(30):9374-9378.
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Poxvirus uracil-DNA glycosylase-An unusual member of the family I uracil-DNA glycosylases. Protein Sci. 2016 12; 25(12):2113-2131.
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Selenium-Mediated Dehalogenation of Halogenated Nucleosides and its Relevance to the DNA Repair Pathway. Angew Chem Int Ed Engl. 2015 Aug 03; 54(32):9298-302.
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Partial uracil-DNA-glycosylase treatment for screening of ancient DNA. Philos Trans R Soc Lond B Biol Sci. 2015 Jan 19; 370(1660):20130624.
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Is there a role for base excision repair in estrogen/estrogen receptor-driven breast cancers? Antioxid Redox Signal. 2014 Dec 01; 21(16):2262-8.
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Genomic uracil homeostasis during normal B cell maturation and loss of this balance during B cell cancer development. Mol Cell Biol. 2014 Nov; 34(21):4019-32.