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TNF-Related Apoptosis-Inducing Ligand

"TNF-Related Apoptosis-Inducing Ligand" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

A transmembrane-protein belonging to the TNF family of intercellular signaling proteins. It is a widely expressed ligand that activates APOPTOSIS by binding to TNF-RELATED APOPTOSIS-INDUCING LIGAND RECEPTORS. The membrane-bound form of the protein can be cleaved by specific CYSTEINE ENDOPEPTIDASES to form a soluble ligand form.


This graph shows the total number of publications written about "TNF-Related Apoptosis-Inducing Ligand" by people in Harvard Catalyst Profiles by year, and whether "TNF-Related Apoptosis-Inducing Ligand" was a major or minor topic of these publication.
Bar chart showing 139 publications over 21 distinct years, with a maximum of 12 publications in 2008 and 2013
To see the data from this visualization as text, click here.
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.