Harvard Catalyst Profiles

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Receptors, sigma

"Receptors, sigma" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

A class of cell surface receptors recognized by its pharmacological profile. Sigma receptors were originally considered to be opioid receptors because they bind certain synthetic opioids. However they also interact with a variety of other psychoactive drugs, and their endogenous ligand is not known (although they can react to certain endogenous steroids). Sigma receptors are found in the immune, endocrine, and nervous systems, and in some peripheral tissues.


This graph shows the total number of publications written about "Receptors, sigma" by people in Harvard Catalyst Profiles by year, and whether "Receptors, sigma" was a major or minor topic of these publication.
Bar chart showing 24 publications over 12 distinct years, with a maximum of 6 publications in 2017
To see the data from this visualization as text, click here.
Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.