"Receptors, Opioid, kappa" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A class of opioid receptors recognized by its pharmacological profile. Kappa opioid receptors bind dynorphins with a higher affinity than endorphins which are themselves preferred to enkephalins.
MeSH Number(s)
D12.776.543.750.100.620.400
D12.776.543.750.720.600.610.400
D12.776.543.750.750.555.610.400
Concept/Terms
Receptors, Opioid, kappa- Receptors, Opioid, kappa
- Opioid Receptors, kappa
- kappa Opioid Receptors
- Receptors, kappa Opioid
- Receptors, kappa
- kappa Receptor
- Receptor, kappa
- kappa Receptors
- kappa Opioid Receptor
- Opioid Receptor, kappa
- Receptor, kappa Opioid
Below are MeSH descriptors whose meaning is more general than "Receptors, Opioid, kappa".
- Chemicals and Drugs [D]
- Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
- Membrane Proteins [D12.776.543]
- Receptors, Cell Surface [D12.776.543.750]
- Receptors, G-Protein-Coupled [D12.776.543.750.100]
- Receptors, Opioid [D12.776.543.750.100.620]
- Receptors, Opioid, kappa [D12.776.543.750.100.620.400]
- Receptors, Neurotransmitter [D12.776.543.750.720]
- Receptors, Neuropeptide [D12.776.543.750.720.600]
- Receptors, Opioid [D12.776.543.750.720.600.610]
- Receptors, Opioid, kappa [D12.776.543.750.720.600.610.400]
- Receptors, Peptide [D12.776.543.750.750]
- Receptors, Neuropeptide [D12.776.543.750.750.555]
- Receptors, Opioid [D12.776.543.750.750.555.610]
- Receptors, Opioid, kappa [D12.776.543.750.750.555.610.400]
Below are MeSH descriptors whose meaning is more specific than "Receptors, Opioid, kappa".
This graph shows the total number of publications written about "Receptors, Opioid, kappa" by people in Harvard Catalyst Profiles by year, and whether "Receptors, Opioid, kappa" was a major or minor topic of these publication.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1993 | 2 | 1 | 3 |
| 1995 | 0 | 1 | 1 |
| 1998 | 1 | 1 | 2 |
| 2001 | 1 | 1 | 2 |
| 2002 | 0 | 2 | 2 |
| 2003 | 1 | 2 | 3 |
| 2004 | 1 | 0 | 1 |
| 2005 | 4 | 1 | 5 |
| 2006 | 2 | 1 | 3 |
| 2007 | 6 | 1 | 7 |
| 2008 | 3 | 0 | 3 |
| 2009 | 4 | 0 | 4 |
| 2010 | 3 | 2 | 5 |
| 2011 | 6 | 0 | 6 |
| 2012 | 4 | 1 | 5 |
| 2013 | 8 | 1 | 9 |
| 2014 | 1 | 0 | 1 |
| 2015 | 3 | 1 | 4 |
| 2016 | 4 | 1 | 5 |
| 2017 | 4 | 1 | 5 |
| 2018 | 4 | 2 | 6 |
| 2019 | 1 | 0 | 1 |
| 2020 | 2 | 1 | 3 |
| 2021 | 2 | 0 | 2 |
| 2022 | 1 | 1 | 2 |
Below are the most recent publications written about "Receptors, Opioid, kappa" by people in Profiles.
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Dichotomous regulation of striatal plasticity by dynorphin. Mol Psychiatry. 2023 01; 28(1):434-447.
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Inhibiting Kiss1 Neurons With Kappa Opioid Receptor Agonists to Treat Polycystic Ovary Syndrome and Vasomotor Symptoms. J Clin Endocrinol Metab. 2022 01 01; 107(1):e328-e347.
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Imaging Kappa Opioid Receptors in the Living Brain with Positron Emission Tomography. Handb Exp Pharmacol. 2022; 271:547-577.
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Blockade of kappa-opioid receptors amplifies microglia-mediated inflammatory responses. Pharmacol Biochem Behav. 2022 01; 212:173301.
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Interactive effects of (±)-trans-U50488 and its stereoisomers with cannabinoids. Pharmacol Biochem Behav. 2021 08; 207:173218.
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Frontal Cortical Monoamine Release, Attention, and Working Memory in a Perinatal Nicotine Exposure Mouse Model Following Kappa Opioid Receptor Antagonism. Cereb Cortex. 2021 01 01; 31(1):483-496.
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Lyophilized Kratom Tea as a Therapeutic Option for Opioid Dependence. Drug Alcohol Depend. 2020 11 01; 216:108310.
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Dipyrone is locally hydrolyzed to 4-methylaminoantipyrine and its antihyperalgesic effect depends on CB2 and kappa-opioid receptors activation. Eur J Pharmacol. 2020 May 05; 874:173005.
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Learned avoidance requires VTA KOR-mediated reductions in dopamine. Neuropharmacology. 2020 05 01; 167:107996.
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Double-blind, placebo-controlled, proof-of-concept trial of a kappa-selective opioid receptor antagonist augmentation in treatment-resistant depression. Ann Clin Psychiatry. 2020 02; 32(4):18-26.