"RNA, Small Nucleolar" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Small nuclear RNAs that are involved in the processing of pre-ribosomal RNA in the nucleolus. Box C/D containing snoRNAs (U14, U15, U16, U20, U21 and U24-U63) direct site-specific methylation of various ribose moieties. Box H/ACA containing snoRNAs (E2, E3, U19, U23, and U64-U72) direct the conversion of specific uridines to pseudouridine. Site-specific cleavages resulting in the mature ribosomal RNAs are directed by snoRNAs U3, U8, U14, U22 and the snoRNA components of RNase MRP and RNase P.
MeSH Number(s)
D13.444.735.628.818.800
D13.444.735.790.552.937.800
Below are MeSH descriptors whose meaning is more general than "RNA, Small Nucleolar".
Below are MeSH descriptors whose meaning is more specific than "RNA, Small Nucleolar".
This graph shows the total number of publications written about "RNA, Small Nucleolar" by people in Harvard Catalyst Profiles by year, and whether "RNA, Small Nucleolar" was a major or minor topic of these publication.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2006 | 1 | 0 | 1 |
| 2008 | 1 | 1 | 2 |
| 2011 | 1 | 2 | 3 |
| 2012 | 0 | 1 | 1 |
| 2013 | 1 | 0 | 1 |
| 2014 | 0 | 1 | 1 |
| 2015 | 2 | 1 | 3 |
| 2016 | 1 | 1 | 2 |
| 2017 | 2 | 1 | 3 |
| 2018 | 2 | 0 | 2 |
| 2019 | 0 | 2 | 2 |
| 2020 | 1 | 2 | 3 |
| 2021 | 1 | 1 | 2 |
| 2022 | 0 | 2 | 2 |
| 2023 | 0 | 1 | 1 |
Below are the most recent publications written about "RNA, Small Nucleolar" by people in Profiles.
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FUS regulates a subset of snoRNA expression and modulates the level of rRNA modifications. Sci Rep. 2023 Feb 20; 13(1):2974.
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Circulating U13 Small Nucleolar RNA as a Potential Biomarker in Huntington's Disease: A Pilot Study. Int J Mol Sci. 2022 Oct 18; 23(20).
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Studies of mutations of assembly factor Hit1 in budding yeast suggest translation defects as the molecular basis for PEHO syndrome. J Biol Chem. 2022 09; 298(9):102261.
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Longitudinal change in blood DNA epigenetic signature after smoking cessation. Epigenetics. 2022 10; 17(10):1098-1109.
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Loss of SNORA73 reprograms cellular metabolism and protects against steatohepatitis. Nat Commun. 2021 09 01; 12(1):5214.
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Reassessment of the involvement of Snord115 in the serotonin 2c receptor pathway in a genetically relevant mouse model. Elife. 2020 10 05; 9.
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Noncoding RNAs in Cardiovascular Disease: Current Knowledge, Tools and Technologies for Investigation, and Future Directions: A Scientific Statement From the American Heart Association. Circ Genom Precis Med. 2020 08; 13(4):e000062.
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Death by lipids: The role of small nucleolar RNAs in metabolic stress. J Biol Chem. 2020 06 19; 295(25):8628-8635.
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DNA-PKcs has KU-dependent function in rRNA processing and haematopoiesis. Nature. 2020 03; 579(7798):291-296.
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Germline NPM1 mutations lead to altered rRNA 2'-O-methylation and cause dyskeratosis congenita. Nat Genet. 2019 10; 51(10):1518-1529.