Hydroxymethylglutaryl-CoA Reductase Inhibitors
"Hydroxymethylglutaryl-CoA Reductase Inhibitors" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Compounds that inhibit HMG-CoA reductases. They have been shown to directly lower cholesterol synthesis.
MeSH Number(s)
D27.505.519.186.071.202.370
D27.505.519.389.370
D27.505.954.557.500.202.370
Concept/Terms
Hydroxymethylglutaryl-CoA Reductase Inhibitors- Hydroxymethylglutaryl-CoA Reductase Inhibitors
- Hydroxymethylglutaryl CoA Reductase Inhibitors
- Inhibitors, Hydroxymethylglutaryl-CoA Reductase
- Reductase Inhibitors, Hydroxymethylglutaryl-CoA
- Statins, HMG-CoA
- HMG-CoA Statins
- Statins, HMG CoA
- Inhibitors, Hydroxymethylglutaryl-CoA
- Hydroxymethylglutaryl-CoA Inhibitors
- Inhibitors, Hydroxymethylglutaryl CoA
- Inhibitors, Hydroxymethylglutaryl-Coenzyme A
- Hydroxymethylglutaryl-Coenzyme A Inhibitors
- Inhibitors, Hydroxymethylglutaryl Coenzyme A
- HMG-CoA Reductase Inhibitors
- HMG CoA Reductase Inhibitors
- Reductase Inhibitors, HMG-CoA
- Inhibitors, HMG-CoA Reductase
- Inhibitors, HMG CoA Reductase
Below are MeSH descriptors whose meaning is more general than "Hydroxymethylglutaryl-CoA Reductase Inhibitors".
Below are MeSH descriptors whose meaning is more specific than "Hydroxymethylglutaryl-CoA Reductase Inhibitors".
This graph shows the total number of publications written about "Hydroxymethylglutaryl-CoA Reductase Inhibitors" by people in Harvard Catalyst Profiles by year, and whether "Hydroxymethylglutaryl-CoA Reductase Inhibitors" was a major or minor topic of these publication.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1993 | 1 | 0 | 1 |
| 1994 | 1 | 3 | 4 |
| 1995 | 0 | 1 | 1 |
| 1997 | 3 | 0 | 3 |
| 1998 | 7 | 1 | 8 |
| 1999 | 3 | 1 | 4 |
| 2000 | 13 | 6 | 19 |
| 2001 | 17 | 4 | 21 |
| 2002 | 29 | 3 | 32 |
| 2003 | 27 | 12 | 39 |
| 2004 | 31 | 6 | 37 |
| 2005 | 45 | 3 | 48 |
| 2006 | 45 | 23 | 68 |
| 2007 | 48 | 17 | 65 |
| 2008 | 38 | 24 | 62 |
| 2009 | 52 | 14 | 66 |
| 2010 | 51 | 18 | 69 |
| 2011 | 69 | 26 | 95 |
| 2012 | 66 | 21 | 87 |
| 2013 | 63 | 22 | 85 |
| 2014 | 78 | 20 | 98 |
| 2015 | 97 | 28 | 125 |
| 2016 | 60 | 35 | 95 |
| 2017 | 82 | 27 | 109 |
| 2018 | 75 | 26 | 101 |
| 2019 | 70 | 35 | 105 |
| 2020 | 71 | 36 | 107 |
| 2021 | 68 | 14 | 82 |
| 2022 | 94 | 4 | 98 |
| 2023 | 47 | 3 | 50 |
Below are the most recent publications written about "Hydroxymethylglutaryl-CoA Reductase Inhibitors" by people in Profiles.
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Investigating the ability to adhere to cardiometabolic medications with different properties: a retrospective cohort study of >500 000 patients in the USA. BMJ Open. 2023 Nov 10; 13(11):e075840.
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Impact of statins based on high-risk plaque features on coronary plaque progression in mild stenosis lesions: results from the PARADIGM study. Eur Heart J Cardiovasc Imaging. 2023 Oct 27; 24(11):1536-1543.
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Serum Cholesterol and Impact of Age on Coronary Heart Disease Death in More Than 4?Million Veterans. J Am Heart Assoc. 2023 Nov 07; 12(21):e030496.
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Statin Use and Coronary Artery Calcification: a Systematic Review and Meta-analysis of Observational Studies and Randomized Controlled Trials. Curr Atheroscler Rep. 2023 11; 25(11):769-784.
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Aggressive LDL-C Lowering and the Brain: Impact on Risk for Dementia and Hemorrhagic Stroke: A Scientific Statement From the American Heart Association. Arterioscler Thromb Vasc Biol. 2023 10; 43(10):e404-e442.
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Adenosine Triphosphate Citrate Lyase and Fatty Acid Synthesis Inhibition: A Narrative Review. JAMA Cardiol. 2023 09 01; 8(9):879-887.
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Association of Statin Use With Risk of Stroke Recurrence After Intracerebral Hemorrhage. Neurology. 2023 Oct 31; 101(18):e1793-e1806.
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Evaluation of Large-Scale Proteomics for Prediction of Cardiovascular Events. JAMA. 2023 08 22; 330(8):725-735.
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Low-Dose Colchicine for Secondary Prevention of Coronary Artery Disease: JACC Review Topic of the Week. J Am Coll Cardiol. 2023 08 15; 82(7):648-660.
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Equation-Based Low-Density Lipoprotein Cholesterol Reclassification and Implications For Lipid-Lowering Therapy. Mayo Clin Proc. 2023 08; 98(8):1258-1259.