Granulomatous Disease, Chronic
"Granulomatous Disease, Chronic" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A recessive X-linked defect of leukocyte function in which phagocytic cells ingest but fail to digest bacteria, resulting in recurring bacterial infections with granuloma formation.
MeSH Number(s)
C15.378.553.774.535
C16.320.322.233
C20.673.774.535
Concept/Terms
Granulomatous Disease, Chronic- Granulomatous Disease, Chronic
- Chronic Granulomatous Disease
- Chronic Granulomatous Diseases
- Disease, Chronic Granulomatous
- Diseases, Chronic Granulomatous
- Granulomatous Diseases, Chronic
Below are MeSH descriptors whose meaning is more general than "Granulomatous Disease, Chronic".
Below are MeSH descriptors whose meaning is more specific than "Granulomatous Disease, Chronic".
This graph shows the total number of publications written about "Granulomatous Disease, Chronic" by people in Harvard Catalyst Profiles by year, and whether "Granulomatous Disease, Chronic" was a major or minor topic of these publication.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1993 | 3 | 1 | 4 |
| 1994 | 2 | 0 | 2 |
| 1995 | 3 | 1 | 4 |
| 1996 | 0 | 1 | 1 |
| 1998 | 1 | 0 | 1 |
| 2000 | 1 | 0 | 1 |
| 2001 | 4 | 3 | 7 |
| 2002 | 2 | 0 | 2 |
| 2003 | 0 | 1 | 1 |
| 2004 | 1 | 1 | 2 |
| 2005 | 1 | 0 | 1 |
| 2006 | 1 | 2 | 3 |
| 2007 | 0 | 1 | 1 |
| 2008 | 2 | 1 | 3 |
| 2009 | 2 | 0 | 2 |
| 2010 | 5 | 0 | 5 |
| 2011 | 1 | 0 | 1 |
| 2012 | 3 | 0 | 3 |
| 2013 | 3 | 0 | 3 |
| 2014 | 2 | 2 | 4 |
| 2015 | 3 | 1 | 4 |
| 2016 | 3 | 0 | 3 |
| 2017 | 1 | 0 | 1 |
| 2018 | 5 | 0 | 5 |
| 2019 | 2 | 0 | 2 |
| 2020 | 3 | 2 | 5 |
| 2021 | 4 | 0 | 4 |
| 2022 | 3 | 0 | 3 |
| 2023 | 1 | 0 | 1 |
Below are the most recent publications written about "Granulomatous Disease, Chronic" by people in Profiles.
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Unlocking the power of NOX2: A comprehensive review on its role in immune regulation. Redox Biol. 2023 08; 64:102795.
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EROS is a selective chaperone regulating the phagocyte NADPH oxidase and purinergic signalling. Elife. 2022 11 24; 11.
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Chronic Granulomatous Disease-Like Presentation of a Child with Autosomal Recessive PKCd Deficiency. J Clin Immunol. 2022 08; 42(6):1244-1253.
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Chronic Granulomatous Disease With Inflammatory Bowel Disease: Clinical Presentation, Treatment, and Outcomes From the USIDNET Registry. J Allergy Clin Immunol Pract. 2022 05; 10(5):1325-1333.e5.
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Neonatal Manifestations of Chronic Granulomatous Disease: MAS/HLH and Necrotizing Pneumonia as Unusual Phenotypes and Review of the Literature. J Clin Immunol. 2022 02; 42(2):299-311.
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Neutrophil-Derived Tumor Necrosis Factor Drives Fungal Acute Lung Injury in Chronic Granulomatous Disease. J Infect Dis. 2021 10 13; 224(7):1225-1235.
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Enhanced homology-directed repair for highly efficient gene editing in hematopoietic stem/progenitor cells. Blood. 2021 05 13; 137(19):2598-2608.
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Preclinical Optimization and Safety Studies of a New Lentiviral Gene Therapy for p47phox-Deficient Chronic Granulomatous Disease. Hum Gene Ther. 2021 09; 32(17-18):949-958.
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Competitive sgRNA Screen Identifies p38 MAPK as a Druggable Target to Improve HSPC Engraftment. Cells. 2020 09 29; 9(10).
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Mice Deficient in NOX2 Display Severe Thymic Atrophy, Lymphopenia, and Reduced Lymphopoiesis in a Zymosan-Induced Model of Systemic Inflammation. Inflammation. 2021 Feb; 44(1):371-382.