Granulocyte-Macrophage Colony-Stimulating Factor
"Granulocyte-Macrophage Colony-Stimulating Factor" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An acidic glycoprotein of MW 23 kDa with internal disulfide bonds. The protein is produced in response to a number of inflammatory mediators by mesenchymal cells present in the hemopoietic environment and at peripheral sites of inflammation. GM-CSF is able to stimulate the production of neutrophilic granulocytes, macrophages, and mixed granulocyte-macrophage colonies from bone marrow cells and can stimulate the formation of eosinophil colonies from fetal liver progenitor cells. GM-CSF can also stimulate some functional activities in mature granulocytes and macrophages.
MeSH Number(s)
D12.644.276.374.410.240.375
D12.776.395.240.300
D12.776.467.374.410.240.375
D23.529.374.410.240.375
Concept/Terms
Granulocyte-Macrophage Colony-Stimulating Factor- Granulocyte-Macrophage Colony-Stimulating Factor
- Granulocyte Macrophage Colony Stimulating Factor
- CSF-2
- Tumor-Cell Human GM Colony-Stimulating Factor
- Tumor Cell Human GM Colony Stimulating Factor
- GM-CSF
- Histamine-Producing Cell-Stimulating Factor
- Cell-Stimulating Factor, Histamine-Producing
- Histamine Producing Cell Stimulating Factor
- TC-GM-CSF
- Colony-Stimulating Factor, Granulocyte-Macrophage
- Colony Stimulating Factor, Granulocyte Macrophage
- CSF-GM
Below are MeSH descriptors whose meaning is more general than "Granulocyte-Macrophage Colony-Stimulating Factor".
Below are MeSH descriptors whose meaning is more specific than "Granulocyte-Macrophage Colony-Stimulating Factor".
This graph shows the total number of publications written about "Granulocyte-Macrophage Colony-Stimulating Factor" by people in Harvard Catalyst Profiles by year, and whether "Granulocyte-Macrophage Colony-Stimulating Factor" was a major or minor topic of these publication.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1993 | 14 | 8 | 22 |
| 1994 | 15 | 11 | 26 |
| 1995 | 10 | 13 | 23 |
| 1996 | 14 | 19 | 33 |
| 1997 | 14 | 6 | 20 |
| 1998 | 6 | 9 | 15 |
| 1999 | 10 | 9 | 19 |
| 2000 | 7 | 6 | 13 |
| 2001 | 5 | 7 | 12 |
| 2002 | 10 | 10 | 20 |
| 2003 | 6 | 11 | 17 |
| 2004 | 2 | 6 | 8 |
| 2005 | 5 | 4 | 9 |
| 2006 | 5 | 9 | 14 |
| 2007 | 3 | 1 | 4 |
| 2008 | 4 | 9 | 13 |
| 2009 | 9 | 4 | 13 |
| 2010 | 9 | 11 | 20 |
| 2011 | 4 | 12 | 16 |
| 2012 | 3 | 6 | 9 |
| 2013 | 1 | 12 | 13 |
| 2014 | 7 | 10 | 17 |
| 2015 | 6 | 11 | 17 |
| 2016 | 8 | 7 | 15 |
| 2017 | 4 | 4 | 8 |
| 2018 | 3 | 3 | 6 |
| 2019 | 6 | 8 | 14 |
| 2020 | 2 | 5 | 7 |
| 2021 | 2 | 2 | 4 |
| 2022 | 3 | 7 | 10 |
| 2023 | 7 | 3 | 10 |
Below are the most recent publications written about "Granulocyte-Macrophage Colony-Stimulating Factor" by people in Profiles.
-
Combined thermal ablation and liposomal granulocyte-macrophage colony stimulation factor increases immune cell trafficking in a small animal tumor model. PLoS One. 2023; 18(10):e0293141.
-
Granulocyte-Macrophage Colony-Stimulating Factor Influence on Soluble and Membrane-Bound ICOS in Combination with Immune Checkpoint Blockade. Cancer Immunol Res. 2023 08 03; 11(8):1100-1113.
-
Phase II Trial of Nelipepimut-S Peptide Vaccine in Women with Ductal Carcinoma In Situ. Cancer Prev Res (Phila). 2023 06 01; 16(6):333-341.
-
Gene-edited and -engineered stem cell platform drives immunotherapy for brain metastatic melanomas. Sci Transl Med. 2023 05 31; 15(698):eade8732.
-
Neutrophil Lifespan Extension with CLON-G and an In Vitro Spontaneous Death Assay. J Vis Exp. 2023 05 12; (195).
-
Steady-state memory-phenotype conventional CD4+ T cells exacerbate autoimmune neuroinflammation in a bystander manner via the Bhlhe40/GM-CSF axis. Exp Mol Med. 2023 05; 55(5):1033-1045.
-
Respiratory tract Moraxella catarrhalis and Klebsiella pneumoniae can promote pathogenicity of myelin-reactive Th17 cells. Mucosal Immunol. 2023 08; 16(4):399-407.
-
Multiparametric Profiling of Neutrophil Function via a High-Throughput Flow Cytometry-Based Assay. Cells. 2023 02 25; 12(5).
-
KIR/KIR-ligand genotypes and clinical outcomes following chemoimmunotherapy in patients with relapsed or refractory neuroblastoma: a report from the Children's Oncology Group. J Immunother Cancer. 2023 02; 11(2).
-
Recombinant GM-CSF for diseases of GM-CSF insufficiency: Correcting dysfunctional mononuclear phagocyte disorders. Front Immunol. 2022; 13:1069444.