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Granulocyte-Macrophage Colony-Stimulating Factor

"Granulocyte-Macrophage Colony-Stimulating Factor" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

An acidic glycoprotein of MW 23 kDa with internal disulfide bonds. The protein is produced in response to a number of inflammatory mediators by mesenchymal cells present in the hemopoietic environment and at peripheral sites of inflammation. GM-CSF is able to stimulate the production of neutrophilic granulocytes, macrophages, and mixed granulocyte-macrophage colonies from bone marrow cells and can stimulate the formation of eosinophil colonies from fetal liver progenitor cells. GM-CSF can also stimulate some functional activities in mature granulocytes and macrophages.


This graph shows the total number of publications written about "Granulocyte-Macrophage Colony-Stimulating Factor" by people in Harvard Catalyst Profiles by year, and whether "Granulocyte-Macrophage Colony-Stimulating Factor" was a major or minor topic of these publication.
Bar chart showing 519 publications over 31 distinct years, with a maximum of 34 publications in 1991 and 1996
To see the data from this visualization as text, click here.
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.