Harvard Catalyst Profiles

Contact, publication, and social network information about Harvard faculty and fellows.

Cocaine

"Cocaine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

An alkaloid ester extracted from the leaves of plants including coca. It is a local anesthetic and vasoconstrictor and is clinically used for that purpose, particularly in the eye, ear, nose, and throat. It also has powerful central nervous system effects similar to the amphetamines and is a drug of abuse. Cocaine, like amphetamines, acts by multiple mechanisms on brain catecholaminergic neurons; the mechanism of its reinforcing effects is thought to involve inhibition of dopamine uptake.


This graph shows the total number of publications written about "Cocaine" by people in Harvard Catalyst Profiles by year, and whether "Cocaine" was a major or minor topic of these publication.
Bar chart showing 647 publications over 30 distinct years, with a maximum of 30 publications in 1991
To see the data from this visualization as text, click here.
Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.