Harvard Catalyst Profiles

Contact, publication, and social network information about Harvard faculty and fellows.

Caspase 2

"Caspase 2" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

A long pro-domain caspase that contains a caspase recruitment domain in its pro-domain region. Activation of this enzyme can occur via the interaction of its caspase recruitment domain with CARD SIGNALING ADAPTOR PROTEINS. Caspase 2 plays a role in APOPTOSIS by cleaving and activating effector pro-caspases. Several isoforms of this protein exist due to multiple alternative splicing of its MESSENGER RNA.


This graph shows the total number of publications written about "Caspase 2" by people in Harvard Catalyst Profiles by year, and whether "Caspase 2" was a major or minor topic of these publication.
Bar chart showing 18 publications over 13 distinct years, with a maximum of 3 publications in 1998 and 2012
To see the data from this visualization as text, click here.
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.